Details for: SF3A2

Gene ID: 8175

Symbol: SF3A2

Ensembl ID: ENSG00000104897

Description: splicing factor 3a subunit 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 158.4748
    Cell Significance Index: -24.6500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 93.5171
    Cell Significance Index: -23.7200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 78.0318
    Cell Significance Index: -32.1500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 69.2542
    Cell Significance Index: -28.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 65.1102
    Cell Significance Index: -30.7400
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 62.2879
    Cell Significance Index: -32.0400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.7567
    Cell Significance Index: -28.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.1638
    Cell Significance Index: -28.5600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.4887
    Cell Significance Index: -22.7400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.4353
    Cell Significance Index: -29.3400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 5.7725
    Cell Significance Index: -17.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.8564
    Cell Significance Index: -8.4400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.8130
    Cell Significance Index: 36.0300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 2.0384
    Cell Significance Index: 22.1600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 1.9073
    Cell Significance Index: 31.9200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6800
    Cell Significance Index: 198.1200
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.5965
    Cell Significance Index: 12.0600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.2813
    Cell Significance Index: 26.8200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.1870
    Cell Significance Index: 34.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9489
    Cell Significance Index: 154.3400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.9123
    Cell Significance Index: 58.8600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7787
    Cell Significance Index: 10.6300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7472
    Cell Significance Index: 674.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5582
    Cell Significance Index: 76.6600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5502
    Cell Significance Index: 59.8400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5380
    Cell Significance Index: 237.8700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5309
    Cell Significance Index: 68.5900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5278
    Cell Significance Index: 37.3300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4367
    Cell Significance Index: 32.5500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3799
    Cell Significance Index: 19.7900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3661
    Cell Significance Index: 16.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3630
    Cell Significance Index: 10.4600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3528
    Cell Significance Index: 16.5800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3379
    Cell Significance Index: 184.5600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3070
    Cell Significance Index: 39.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2915
    Cell Significance Index: 57.8500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2885
    Cell Significance Index: 8.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2839
    Cell Significance Index: 7.5800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2507
    Cell Significance Index: 50.2900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2499
    Cell Significance Index: 17.2800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2278
    Cell Significance Index: 5.9900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2265
    Cell Significance Index: 27.8600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2083
    Cell Significance Index: 5.8200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1947
    Cell Significance Index: 35.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1877
    Cell Significance Index: 18.5700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1852
    Cell Significance Index: 9.6200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1684
    Cell Significance Index: 4.5800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1620
    Cell Significance Index: 3.5100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1400
    Cell Significance Index: 50.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1354
    Cell Significance Index: 25.7700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1246
    Cell Significance Index: 6.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1136
    Cell Significance Index: 3.9900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1031
    Cell Significance Index: 71.2800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1008
    Cell Significance Index: 6.3500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0636
    Cell Significance Index: 1.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0215
    Cell Significance Index: 40.4400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0071
    Cell Significance Index: 13.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0071
    Cell Significance Index: 10.9500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0060
    Cell Significance Index: -0.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0075
    Cell Significance Index: -0.2400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0107
    Cell Significance Index: -0.6000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0135
    Cell Significance Index: -18.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0158
    Cell Significance Index: -1.6100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0201
    Cell Significance Index: -15.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0276
    Cell Significance Index: -17.5200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0323
    Cell Significance Index: -23.6500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0338
    Cell Significance Index: -25.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0431
    Cell Significance Index: -19.5600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0450
    Cell Significance Index: -25.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0517
    Cell Significance Index: -32.3100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0534
    Cell Significance Index: -9.1200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0599
    Cell Significance Index: -1.5300
  • Cell Name: kidney cell (CL1000497)
    Fold Change: -0.0676
    Cell Significance Index: -0.5400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0845
    Cell Significance Index: -24.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1129
    Cell Significance Index: -13.1600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1136
    Cell Significance Index: -16.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1205
    Cell Significance Index: -13.8100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1572
    Cell Significance Index: -12.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1635
    Cell Significance Index: -34.4400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1716
    Cell Significance Index: -4.2900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1886
    Cell Significance Index: -11.5900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.2374
    Cell Significance Index: -4.2000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2422
    Cell Significance Index: -4.1500
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2581
    Cell Significance Index: -3.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2599
    Cell Significance Index: -27.0600
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: -0.2652
    Cell Significance Index: -1.2900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.2903
    Cell Significance Index: -4.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3077
    Cell Significance Index: -3.1900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3268
    Cell Significance Index: -6.9600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3387
    Cell Significance Index: -6.2600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -0.3427
    Cell Significance Index: -2.1200
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.3688
    Cell Significance Index: -4.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3718
    Cell Significance Index: -25.0000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3741
    Cell Significance Index: -29.6300
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.4128
    Cell Significance Index: -2.7400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.4357
    Cell Significance Index: -3.6600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4516
    Cell Significance Index: -27.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.4610
    Cell Significance Index: -20.3900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.4767
    Cell Significance Index: -3.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4779
    Cell Significance Index: -12.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Splicing Factor**: SF3A2 is a subunit of the spliceosome, a complex molecular machine responsible for catalyzing the splicing of introns from pre-mRNA. 2. **RNA Binding**: SF3A2 interacts with RNA, specifically with U2 snRNP, a component of the spliceosome. 3. **Zinc Ion Binding**: SF3A2 contains a zinc ion-binding motif, which is essential for its function in the spliceosome. 4. **Cell Type Specificity**: SF3A2 is significantly expressed in specific cell types, including B cells, hematopoietic stem cells, and immune cells. **Pathways and Functions** 1. **Catalytic Step 2 Spliceosome**: SF3A2 is involved in the catalytic step 2 of the spliceosome, where the lariat-shaped intron is removed from the pre-mRNA. 2. **Metabolism of RNA**: SF3A2 is involved in the metabolism of RNA, specifically in the splicing of introns from pre-mRNA. 3. **mRNA 3'-Splice Site Recognition**: SF3A2 recognizes the 3'-splice site of the intron, which is essential for the splicing process. 4. **mRNA Processing**: SF3A2 is involved in the processing of capped intron-containing pre-mRNA. 5. **Spliceosomal Complex Assembly**: SF3A2 is involved in the assembly of the spliceosomal complex, which is essential for the splicing process. **Clinical Significance** 1. **RNA Splicing Defects**: SF3A2 mutations or dysregulation can lead to defects in RNA splicing, resulting in abnormalities in protein expression and function. 2. **Immune Cell Dysfunction**: SF3A2 dysregulation in immune cells can lead to impaired immune function and increased susceptibility to infections. 3. **Cancer**: SF3A2 dysregulation has been implicated in the development of certain types of cancer, such as lymphoma and leukemia. 4. **Neurological Disorders**: SF3A2 dysregulation has been implicated in neurological disorders, such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). In conclusion, SF3A2 is a crucial gene involved in the process of RNA splicing, which is essential for the production of mature mRNA from pre-mRNA. Its dysregulation can lead to defects in RNA splicing, resulting in abnormalities in protein expression and function, and can be implicated in various diseases, including cancer and neurological disorders. Further research is needed to fully understand the role of SF3A2 in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 2810690294

Symbol: SF3A2_HUMAN

Name: Splicing factor 3A subunit 2

UniProtKB Accession Codes:

Q15428 B2RBU1 D6W605 O75245

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 9 EMDB 31 Ensembl 1 ExpressionAtlas 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 33 PDBsum 33 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8211113

Title: Correspondence between a mammalian spliceosome component and an essential yeast splicing factor.

PubMed ID: 8211113

DOI: 10.1126/science.8211113

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9710584

Title: CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif.

PubMed ID: 9710584

DOI: 10.1128/mcb.18.9.5000

PubMed ID: 10882114

Title: Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.

PubMed ID: 10882114

DOI: 10.1016/s1097-2765(00)80318-4

PubMed ID: 11533230

Title: Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation.

PubMed ID: 11533230

DOI: 10.1128/mcb.21.19.6406-6417.2001

PubMed ID: 11991638

Title: Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis.

PubMed ID: 11991638

DOI: 10.1017/s1355838202021088

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21349847

Title: Interaction domains and nuclear targeting signals in subunits of the U2 small nuclear ribonucleoprotein particle-associated splicing factor SF3a.

PubMed ID: 21349847

DOI: 10.1074/jbc.m110.201491

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 29361316

Title: Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.

PubMed ID: 29361316

DOI: 10.1016/j.cell.2018.01.010

PubMed ID: 29360106

Title: Structure of the human activated spliceosome in three conformational states.

PubMed ID: 29360106

DOI: 10.1038/cr.2018.14

PubMed ID: 30315277

Title: Structures of the human pre-catalytic spliceosome and its precursor spliceosome.

PubMed ID: 30315277

DOI: 10.1038/s41422-018-0094-7

PubMed ID: 32494006

Title: Molecular architecture of the human 17S U2 snRNP.

PubMed ID: 32494006

DOI: 10.1038/s41586-020-2344-3

PubMed ID: 34822310

Title: Structural basis of branch site recognition by the human spliceosome.

PubMed ID: 34822310

DOI: 10.1126/science.abm4245

PubMed ID: 36797247

Title: Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.

PubMed ID: 36797247

DOI: 10.1038/s41467-023-36489-x

Sequence Information:

  • Length: 464
  • Mass: 49256
  • Checksum: FA46F064A55EA2CE
  • Sequence:
    • MDFQHRPGGK TGSGGVASSS ESNRDRRERL RQLALETIDI NKDPYFMKNH LGSYECKLCL 
TLHNNEGSYL AHTQGKKHQT NLARRAAKEA KEAPAQPAPE KVKVEVKKFV KIGRPGYKVT 
KQRDSEMGQQ SLLFQIDYPE IAEGIMPRHR FMSAYEQRIE PPDRRWQYLL MAAEPYETIA 
FKVPSREIDK AEGKFWTHWN RETKQFFLQF HFKMEKPPAP PSLPAGPPGV KRPPPPLMNG 
LPPRPPLPES LPPPPPGGLP LPPMPPTGPA PSGPPGPPQL PPPAPGVHPP APVVHPPASG 
VHPPAPGVHP PAPGVHPPAP GVHPPTSGVH PPAPGVHPPA PGVHPPAPGV HPPAPGVHPP 
APGVHPPPSA GVHPQAPGVH PAAPAVHPQA PGVHPPAPGM HPQAPGVHPQ PPGVHPSAPG 
VHPQPPGVHP SNPGVHPPTP MPPMLRPPLP SEGPGNIPPP PPTN

Genular Protein ID: 338267837

Symbol: Q05DF2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q05DF2

Database IDs:

ARBA 8 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 481
  • Mass: 51476
  • Checksum: ADF3180150B6F5E2
  • Sequence:
    • MDFQHRPGGK TGSGGVASSS ESNRDRRERL RQLALETIDI NKDPYFMKNH LGSYECKLCL 
TLHNNEGSYL AHTQGKKHQT NLARRAAKEA KEAPAQPAPE KVKVEVKKFV KIGRPGYKVT 
KQRDSEMGQQ SLLFQIDYPE IAEGIMPRHR FMSAYEQRIE PPDRRWQYLL MAAEPYETIA 
FKVPSREIDK AEGKFWTHWN RETKQFFLQF HFKMEKPPAP PSLPAGPPGV KRPPPPLMNG 
LPPRPPLPES LPPPPPGGLP LPPMPPTGPA PSGPPGPPQL PPPAPGVHPP APVVHPPASG 
VHPPAPGVHP PAPGVHPPAP GVHPPTSGVH PPAPGVHPPA PGVHPPAPGV HPPAPGVHPP 
APGVHPPPSA GVHPQAPGVH PAAPAVHPQA PGVHPPAPGM HPQAPGVHPQ PPGVHPSAPG 
VHPQPPGVHP SNPGVHPPTP MPPMLRPPLP SEGPGNIPPP PPKKKKKKKK KKKKKKKKKK 
K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.