Details for: FCER2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 26.8732
Cell Significance Index: -4.1800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 16.9924
Cell Significance Index: -4.3100 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 5.1968
Cell Significance Index: 23.2400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 3.3253
Cell Significance Index: -4.1000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.1234
Cell Significance Index: 17.3800 - Cell Name: follicular B cell (CL0000843)
Fold Change: 0.7757
Cell Significance Index: 3.8800 - Cell Name: centrocyte (CL0009111)
Fold Change: 0.6843
Cell Significance Index: 2.1100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.4357
Cell Significance Index: 51.3800 - Cell Name: B-1b B cell (CL0000821)
Fold Change: 0.3908
Cell Significance Index: 1.9600 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.1540
Cell Significance Index: 0.9300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.1115
Cell Significance Index: 2.7800 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.0849
Cell Significance Index: 1.0500 - Cell Name: helper T cell (CL0000912)
Fold Change: 0.0352
Cell Significance Index: 0.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0333
Cell Significance Index: 0.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0039
Cell Significance Index: 0.7900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0014
Cell Significance Index: -2.5500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0040
Cell Significance Index: -7.4300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0050
Cell Significance Index: -3.7900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0050
Cell Significance Index: -7.6400 - Cell Name: mucous neck cell (CL0000651)
Fold Change: -0.0052
Cell Significance Index: -0.0200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0055
Cell Significance Index: -4.0900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0057
Cell Significance Index: -3.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0058
Cell Significance Index: -7.9300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0067
Cell Significance Index: -4.2100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0069
Cell Significance Index: -2.4700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0070
Cell Significance Index: -3.9400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0071
Cell Significance Index: -0.1900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0072
Cell Significance Index: -1.4200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0080
Cell Significance Index: -0.3500 - Cell Name: centroblast (CL0009112)
Fold Change: -0.0086
Cell Significance Index: -0.0200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0105
Cell Significance Index: -1.7900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0108
Cell Significance Index: -4.8900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0123
Cell Significance Index: -2.2200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0129
Cell Significance Index: -3.7000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0158
Cell Significance Index: -1.0200 - Cell Name: naive B cell (CL0000788)
Fold Change: -0.0190
Cell Significance Index: -0.2000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0197
Cell Significance Index: -2.8600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0197
Cell Significance Index: -4.1400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0296
Cell Significance Index: -3.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0312
Cell Significance Index: -3.8400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0355
Cell Significance Index: -4.8800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0368
Cell Significance Index: -4.7500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0419
Cell Significance Index: -4.3600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0440
Cell Significance Index: -4.4900 - Cell Name: transitional stage B cell (CL0000818)
Fold Change: -0.0524
Cell Significance Index: -0.4600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0540
Cell Significance Index: -0.4400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0552
Cell Significance Index: -3.7100 - Cell Name: memory B cell (CL0000787)
Fold Change: -0.0667
Cell Significance Index: -0.7100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0669
Cell Significance Index: -5.1300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0690
Cell Significance Index: -1.8500 - Cell Name: osteoclast (CL0000092)
Fold Change: -0.0700
Cell Significance Index: -0.7200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0702
Cell Significance Index: -1.4700 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.0718
Cell Significance Index: -1.0500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0768
Cell Significance Index: -3.8800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0809
Cell Significance Index: -4.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0814
Cell Significance Index: -2.2700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0831
Cell Significance Index: -4.3300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0841
Cell Significance Index: -2.1600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0863
Cell Significance Index: -4.0600 - Cell Name: B-1a B cell (CL0000820)
Fold Change: -0.0875
Cell Significance Index: -0.4700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0925
Cell Significance Index: -4.3200 - Cell Name: mature B cell (CL0000785)
Fold Change: -0.0956
Cell Significance Index: -0.6200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0973
Cell Significance Index: -3.4100 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.0983
Cell Significance Index: -1.6700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1004
Cell Significance Index: -1.9600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1030
Cell Significance Index: -5.3500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1049
Cell Significance Index: -4.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.1052
Cell Significance Index: -3.3500 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.1083
Cell Significance Index: -1.5400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1085
Cell Significance Index: -6.0900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1103
Cell Significance Index: -3.6100 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1104
Cell Significance Index: -2.0400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1212
Cell Significance Index: -4.5900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1250
Cell Significance Index: -3.6700 - Cell Name: B cell (CL0000236)
Fold Change: -0.1286
Cell Significance Index: -1.5200 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.1286
Cell Significance Index: -1.4100 - Cell Name: ionocyte (CL0005006)
Fold Change: -0.1301
Cell Significance Index: -1.3600 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1308
Cell Significance Index: -5.3600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.1348
Cell Significance Index: -1.4700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1359
Cell Significance Index: -3.6300 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: -0.1389
Cell Significance Index: -1.3300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1402
Cell Significance Index: -4.0000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1414
Cell Significance Index: -3.8500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1450
Cell Significance Index: -4.2700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1467
Cell Significance Index: -3.6600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1468
Cell Significance Index: -3.8600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1495
Cell Significance Index: -3.8200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1526
Cell Significance Index: -2.1900 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1615
Cell Significance Index: -2.3500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1619
Cell Significance Index: -3.5500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1633
Cell Significance Index: -4.6800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1685
Cell Significance Index: -3.6400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1710
Cell Significance Index: -3.6300 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1742
Cell Significance Index: -2.9300 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1759
Cell Significance Index: -4.4800 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.1780
Cell Significance Index: -1.5400 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1800
Cell Significance Index: -3.5600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1804
Cell Significance Index: -6.3400 - Cell Name: lymphocyte (CL0000542)
Fold Change: -0.1808
Cell Significance Index: -2.4600 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1814
Cell Significance Index: -6.6600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1313073264
Symbol: FCER2_HUMAN
Name: Low affinity immunoglobulin epsilon Fc receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2949326
Title: Human lymphocyte Fc receptor for IgE: sequence homology of its cloned cDNA with animal lectins.
PubMed ID: 2949326
PubMed ID: 2877743
Title: Molecular structure of human lymphocyte receptor for immunoglobulin E.
PubMed ID: 2877743
PubMed ID: 3034567
Title: Cloning and expression of the cDNA coding for a human lymphocyte IgE receptor.
PubMed ID: 3034567
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 2972386
Title: Two species of human Fc epsilon receptor II (Fc epsilon RII/CD23): tissue-specific and IL-4-specific regulation of gene expression.
PubMed ID: 2972386
PubMed ID: 1417742
Title: Partial characterization of natural and recombinant human soluble CD23.
PubMed ID: 1417742
DOI: 10.1042/bj2860819
PubMed ID: 2167225
Title: IgE-dependent antigen focusing by human B lymphocytes is mediated by the low-affinity receptor for IgE.
PubMed ID: 2167225
PubMed ID: 1386409
Title: CD21 is a ligand for CD23 and regulates IgE production.
PubMed ID: 1386409
DOI: 10.1038/358505a0
PubMed ID: 7544003
Title: The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen.
PubMed ID: 7544003
PubMed ID: 17389606
Title: The low affinity IgE receptor (CD23) is cleaved by the metalloproteinase ADAM10.
PubMed ID: 17389606
PubMed ID: 22615937
Title: Proteomic analysis of S-acylated proteins in human B cells reveals palmitoylation of the immune regulators CD20 and CD23.
PubMed ID: 22615937
PubMed ID: 37453717
Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.
PubMed ID: 37453717
PubMed ID: 8142907
Title: Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23).
PubMed ID: 8142907
PubMed ID: 8745401
Title: Structure-based modeling of the ligand binding domain of the human cell surface receptor CD23 and comparison of two independently derived molecular models.
PubMed ID: 8745401
PubMed ID: 16172256
Title: The structure of human CD23 and its interactions with IgE and CD21.
PubMed ID: 16172256
DOI: 10.1084/jem.20050811
PubMed ID: 16765898
Title: Structural changes in the lectin domain of CD23, the low-affinity IgE receptor, upon calcium binding.
PubMed ID: 16765898
PubMed ID: 23424103
Title: Mutations in the autoregulatory domain of beta-tubulin 4a cause hereditary dystonia.
PubMed ID: 23424103
DOI: 10.1002/ana.23832
Sequence Information:
- Length: 321
- Mass: 36469
- Checksum: F86708C0E6515B87
- Sequence:
MEEGQYSEIE ELPRRRCCRR GTQIVLLGLV TAALWAGLLT LLLLWHWDTT QSLKQLEERA ARNVSQVSKN LESHHGDQMA QKSQSTQISQ ELEELRAEQQ RLKSQDLELS WNLNGLQADL SSFKSQELNE RNEASDLLER LREEVTKLRM ELQVSSGFVC NTCPEKWINF QRKCYYFGKG TKQWVHARYA CDDMEGQLVS IHSPEEQDFL TKHASHTGSW IGLRNLDLKG EFIWVDGSHV DYSNWAPGEP TSRSQGEDCV MMRGSGRWND AFCDRKLGAW VCDRLATCTP PASEGSAESM GPDSRPDPDG RLPTPSAPLH S
Genular Protein ID: 2792490569
Symbol: K3W4U1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 320
- Mass: 36299
- Checksum: 7BAE201DC57FCF85
- Sequence:
MNPPSQEIEE LPRRRCCRRG TQIVLLGLVT AALWAGLLTL LLLWHWDTTQ SLKQLEERAA RNVSQVSKNL ESHHGDQMAQ KSQSTQISQE LEELRAEQQR LKSQDLELSW NLNGLQADLS SFKSQELNER NEASDLLERL REEVTKLRME LQVSSGFVCN TCPEKWINFQ RKCYYFGKGT KQWVHARYAC DDMEGQLVSI HSPEEQDFLT KHASHTGSWI GLRNLDLKGE FIWVDGSHVD YSNWAPGEPT SRSQGEDCVM MRGSGRWNDA FCDRKLGAWV CDRLATCTPP ASEGSAESMG PDSRPDPDGR LPTPSAPLHS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.