Details for: CYFIP2

Gene ID: 26999

Symbol: CYFIP2

Ensembl ID: ENSG00000055163

Description: cytoplasmic FMR1 interacting protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 263.9104
    Cell Significance Index: -41.0500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 144.0014
    Cell Significance Index: -36.5300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 92.3061
    Cell Significance Index: -37.5000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.4214
    Cell Significance Index: -42.6900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 84.7808
    Cell Significance Index: -43.6100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 39.6756
    Cell Significance Index: -37.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.2778
    Cell Significance Index: -41.0300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.8269
    Cell Significance Index: -45.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.6957
    Cell Significance Index: -34.0100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.6103
    Cell Significance Index: -10.0900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.7557
    Cell Significance Index: 78.6400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.6077
    Cell Significance Index: 175.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4029
    Cell Significance Index: 482.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.0208
    Cell Significance Index: 724.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.8624
    Cell Significance Index: 82.3800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.8396
    Cell Significance Index: 69.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.8117
    Cell Significance Index: 179.2200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.6858
    Cell Significance Index: 103.6200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.6781
    Cell Significance Index: 40.2500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.2898
    Cell Significance Index: 27.4700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.1320
    Cell Significance Index: 782.9700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.1144
    Cell Significance Index: 8.5900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.0599
    Cell Significance Index: 154.0700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.9818
    Cell Significance Index: 115.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9500
    Cell Significance Index: 857.7700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.8972
    Cell Significance Index: 26.3500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.8819
    Cell Significance Index: 19.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8562
    Cell Significance Index: 65.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6040
    Cell Significance Index: 98.2300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.5671
    Cell Significance Index: 7.9300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.5285
    Cell Significance Index: 14.1600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5279
    Cell Significance Index: 34.0600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5141
    Cell Significance Index: 55.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5115
    Cell Significance Index: 26.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.4828
    Cell Significance Index: 353.9700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4415
    Cell Significance Index: 5.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.3971
    Cell Significance Index: 31.4500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.3763
    Cell Significance Index: 4.8800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3291
    Cell Significance Index: 5.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2981
    Cell Significance Index: 59.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2324
    Cell Significance Index: 41.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.2056
    Cell Significance Index: 11.5400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1215
    Cell Significance Index: 23.1300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1102
    Cell Significance Index: 203.1500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1043
    Cell Significance Index: 56.9800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0718
    Cell Significance Index: 135.2700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0716
    Cell Significance Index: 110.2700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0715
    Cell Significance Index: 45.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0705
    Cell Significance Index: 95.8600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0167
    Cell Significance Index: 0.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0098
    Cell Significance Index: -6.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0101
    Cell Significance Index: -7.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0274
    Cell Significance Index: -12.4200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0363
    Cell Significance Index: -27.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0430
    Cell Significance Index: -1.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0437
    Cell Significance Index: -24.6300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0463
    Cell Significance Index: -2.1000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0488
    Cell Significance Index: -21.5800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0888
    Cell Significance Index: -15.1700
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0893
    Cell Significance Index: -0.8500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0896
    Cell Significance Index: -9.1500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0901
    Cell Significance Index: -18.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1008
    Cell Significance Index: -12.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1231
    Cell Significance Index: -35.4200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1339
    Cell Significance Index: -1.6700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1352
    Cell Significance Index: -9.3500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1555
    Cell Significance Index: -3.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1597
    Cell Significance Index: -18.6100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1758
    Cell Significance Index: -2.6000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1788
    Cell Significance Index: -3.5900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1878
    Cell Significance Index: -19.5500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.2167
    Cell Significance Index: -29.7600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2225
    Cell Significance Index: -4.4000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2336
    Cell Significance Index: -14.7200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2354
    Cell Significance Index: -5.1000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2549
    Cell Significance Index: -13.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2554
    Cell Significance Index: -29.2600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2598
    Cell Significance Index: -2.8300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.2599
    Cell Significance Index: -2.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2704
    Cell Significance Index: -34.9400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2759
    Cell Significance Index: -35.3700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2897
    Cell Significance Index: -6.0100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2973
    Cell Significance Index: -33.9400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3267
    Cell Significance Index: -8.7200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3460
    Cell Significance Index: -8.8400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3474
    Cell Significance Index: -21.3000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3615
    Cell Significance Index: -6.0900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3630
    Cell Significance Index: -11.8900
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3684
    Cell Significance Index: -6.3700
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.3771
    Cell Significance Index: -4.7600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3841
    Cell Significance Index: -5.5000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4087
    Cell Significance Index: -13.0900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4154
    Cell Significance Index: -13.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4287
    Cell Significance Index: -5.1100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4309
    Cell Significance Index: -6.3600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.4340
    Cell Significance Index: -12.1300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4370
    Cell Significance Index: -9.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4973
    Cell Significance Index: -37.0700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5124
    Cell Significance Index: -11.0700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.5216
    Cell Significance Index: -6.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Cellular localization**: CYFIP2 is localized to the cytoplasm, where it interacts with other proteins and regulates various cellular processes. 2. **Expression pattern**: CYFIP2 is expressed in multiple cell types, including inhibitory interneurons, astrocytes, and epithelial cells of the kidney. 3. **Interactions with FMR1**: CYFIP2 interacts with FMR1, a protein associated with Fragile X syndrome, suggesting a potential role in regulating FMR1-mediated signaling pathways. 4. **Signaling pathways**: CYFIP2 is involved in multiple signaling pathways, including those regulating actin dynamics, protein binding, and GTPase cycles. **Pathways and Functions** CYFIP2 is involved in various signaling pathways, including: 1. **Actin dynamics regulation**: CYFIP2 regulates actin dynamics, which is essential for cellular processes such as phagocytosis, cell migration, and neuronal development. 2. **Protein binding**: CYFIP2 interacts with various proteins, including FMR1, to regulate protein-protein interactions and signaling pathways. 3. **GTPase cycles**: CYFIP2 is involved in GTPase cycles, including those regulating Rho GTPases, Rac1 GTPases, and Miro GTPases, which are essential for regulating cellular processes such as cytoskeleton dynamics and cell migration. 4. **Neurotrophin signaling pathway**: CYFIP2 is involved in the positive regulation of neurotrophin trk receptor signaling pathway, which is essential for neuronal development and survival. 5. **Immune response**: CYFIP2 is involved in the regulation of immune responses, including phagocytosis and Fcγ receptor-mediated phagocytosis. **Clinical Significance** The dysregulation of CYFIP2 has been implicated in various diseases, including: 1. **Fragile X syndrome**: CYFIP2 interacts with FMR1, a protein associated with Fragile X syndrome, suggesting a potential role in regulating FMR1-mediated signaling pathways. 2. **Neurodegenerative diseases**: CYFIP2's involvement in neurotrophin signaling pathway and GTPase cycles suggests a potential role in neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. 3. **Immune disorders**: CYFIP2's involvement in immune response regulation suggests a potential role in immune disorders such as rheumatoid arthritis and multiple sclerosis. In conclusion, CYFIP2 is a gene that plays a crucial role in regulating various cellular processes, including immune response, neuronal development, and cell morphology. Its involvement in multiple signaling pathways highlights its importance in regulating cellular functions, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the role of CYFIP2 in human disease.

Genular Protein ID: 3773202695

Symbol: CYFP2_HUMAN

Name: Cytoplasmic FMR1-interacting protein 2

UniProtKB Accession Codes:

Q96F07 A6NLT2 D3DQJ3 Q53EN5 Q9NTK4 Q9ULQ2 Q9UN29

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 3 ExpressionAtlas 1 GO 21 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 6 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10449408

Title: Increased apoptosis induction by 121F mutant p53.

PubMed ID: 10449408

DOI: 10.1093/emboj/18.16.4424

PubMed ID: 10574461

Title: Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.

PubMed ID: 10574461

DOI: 10.1093/dnares/6.5.329

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15048733

Title: CYFIP2 is highly abundant in CD4+ cells from multiple sclerosis patients and is involved in T cell adhesion.

PubMed ID: 15048733

DOI: 10.1002/eji.200324726

PubMed ID: 15731336

Title: Evolutionarily conserved human targets of adenosine to inosine RNA editing.

PubMed ID: 15731336

DOI: 10.1093/nar/gki239

PubMed ID: 17245118

Title: CYFIP2, a direct p53 target, is leptomycin-B sensitive.

PubMed ID: 17245118

DOI: 10.4161/cc.6.1.3665

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24658146

Title: Subcellular fractionation and localization studies reveal a direct interaction of the fragile X mental retardation protein (FMRP) with nucleolin.

PubMed ID: 24658146

DOI: 10.1371/journal.pone.0091465

PubMed ID: 29534297

Title: De novo hotspot variants in CYFIP2 cause early-onset epileptic encephalopathy.

PubMed ID: 29534297

DOI: 10.1002/ana.25208

Sequence Information:

  • Length: 1278
  • Mass: 148399
  • Checksum: D6562B1204DC2463
  • Sequence:
    • MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN AFVTGIARYI 
EQATVHSSMN EMLEEGHEYA VMLYTWRSCS RAIPQVKCNE QPNRVEIYEK TVEVLEPEVT 
KLMKFMYFQR KAIERFCSEV KRLCHAERRK DFVSEAYLLT LGKFINMFAV LDELKNMKCS 
VKNDHSAYKR AAQFLRKMAD PQSIQESQNL SMFLANHNRI TQCLHQQLEV IPGYEELLAD 
IVNICVDYYE NKMYLTPSEK HMLLKVMGFG LYLMDGNVSN IYKLDAKKRI NLSKIDKFFK 
QLQVVPLFGD MQIELARYIK TSAHYEENKS KWTCTQSSIS PQYNICEQMV QIRDDHIRFI 
SELARYSNSE VVTGSGLDSQ KSDEEYRELF DLALRGLQLL SKWSAHVMEV YSWKLVHPTD 
KFCNKDCPGT AEEYERATRY NYTSEEKFAF VEVIAMIKGL QVLMGRMESV FNQAIRNTIY 
AALQDFAQVT LREPLRQAVR KKKNVLISVL QAIRKTICDW EGGREPPNDP CLRGEKDPKG 
GFDIKVPRRA VGPSSTQACQ WSPRALFHPT GGTQGRRGCR SLLYMVRTML ESLIADKSGS 
KKTLRSSLDG PIVLAIEDFH KQSFFFTHLL NISEALQQCC DLSQLWFREF FLELTMGRRI 
QFPIEMSMPW ILTDHILETK EPSMMEYVLY PLDLYNDSAY YALTKFKKQF LYDEIEAEVN 
LCFDQFVYKL ADQIFAYYKA MAGSVLLDKR FRAECKNYGV IIPYPPSNRY ETLLKQRHVQ 
LLGRSIDLNR LITQRISAAM YKSLDQAISR FESEDLTSIV ELEWLLEINR LTHRLLCKHM 
TLDSFDAMFR EANHNVSAPY GRITLHVFWE LNFDFLPNYC YNGSTNRFVR TAIPFTQEPQ 
RDKPANVQPY YLYGSKPLNI AYSHIYSSYR NFVGPPHFKT ICRLLGYQGI AVVMEELLKI 
VKSLLQGTIL QYVKTLIEVM PKICRLPRHE YGSPGILEFF HHQLKDIIEY AELKTDVFQS 
LREVGNAILF CLLIEQALSQ EEVCDLLHAA PFQNILPRVY IKEGERLEVR MKRLEAKYAP 
LHLVPLIERL GTPQQIAIAR EGDLLTKERL CCGLSMFEVI LTRIRSYLQD PIWRGPPPTN 
GVMHVDECVE FHRLWSAMQF VYCIPVGTNE FTAEQCFGDG LNWAGCSIIV LLGQQRRFDL 
FDFCYHLLKV QRQDGKDEII KNVPLKKMAD RIRKYQILNN EVFAILNKYM KSVETDSSTV 
EHVRCFQPPI HQSLATTC

Genular Protein ID: 2648910735

Symbol: B7Z8N7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z8N7

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRINTS 1 PeptideAtlas 1 Pfam 3 RefSeq 1

Sequence Information:

  • Length: 1227
  • Mass: 142588
  • Checksum: 06089AEF1973E007
  • Sequence:
    • MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN AFVTGIARYI 
EQATVHSSMV KCNEQPNRVE IYEKTVEVLE PEVTKLMKFM YFQRKAIERF CSEVKRLCHA 
ERRKDFVSEA YLLTLGKFIN MFAVLDELKN MKCSVKNDHS AYKRAAQFLR KMADPQSIQE 
SQNLSMFLAN HNRITQCLHQ QLEVIPGYEE LLADIVNICV DYYENKMYLT PSEKHMLLKV 
MGFGLYLMDG NVSNIYKLDA KKRINLSKID KFFKQLQVVP LFGDMQIELA RYIETSAHYE 
ENKSKWTCTQ SSISPQYNIC EQMVQIRDDH IRFISELARY SNSEVVTGSG LDSQKSDEEY 
RELFDLALRG LQLLSKWSAH VMEVYSWKLV HPTDKFCNKD CPGTAEEYER ATRYNYTSEE 
KFAFVEVIAM IKGLQVLMGR MESVFNQAIR NTIYAALQDF AQVTLREPLR QAVRKKKNVL 
ISVLQAIRKT ICDWEGGREP PNDPCLRGEK DPKGGFDIKV PRRAVGPPST QLYMVRTMLE 
SLIADKSGSK KTLRSSLDGP IVLAIEDFHK QSFFFTHLLN ISEALQQCCD LSQLWFREFF 
LELTMGRRIQ FPIEMSMPWI LTDHILETKE PSMMEYVLYP LDLYNDSAYY ALTKFKKQFL 
YDEIEAEVNL CFDQFVYKLA DQIFAYYKAM AGSVLLDKRF RAECKNYGVI IPYPPSNRYE 
TLLKQRHVQL LGRSIDLNRL ITQRISAAMY KSLDQAISRF ESEDLTSIVE LEWLLEINRL 
THRLLCKHMT LDSFDAMFRE ANHNVSAPYG RITLHVFWEL NFDFLPNYCY NGSTNRFVRT 
AIPFTQEPQR DKPANVQPYY LYGSKPLNIA YSHIYSSYRN FVGPPHFKTI CRLLGYQGIA 
VVMEELLKIV KSLLQGTILQ YVKTLIEVMP KICRLPRHEY GSPGILEFFH HQLKDIIEYA 
ELKTDVFQSL REVGNAILFC LLIEQALSQE EVCDLLHAAP FQNILPRVYI KEGERLEVRM 
KRLEAKYAPL HLVPLIERLG TPQQIAIARE GDLLTKERLC CGLSMFEVIL TRIRSYLQDP 
IWRGPPPTNG VMHVDECVEF HRLWSAMQFV YCIPVGTNEF TAEQCFGDGL NWAGCSIIVL 
LGQQRRFDLF DFCYHLLKVQ RQDGKDEIIK NVPLKKMADR IRKYQILNNE VFAILNKYMK 
SVETDSSTVE HVRCFQPPIH QSLATTC

Genular Protein ID: 1145219384

Symbol: E7EVJ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EVJ5

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 ExpressionAtlas 1 GO 4 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PRIDE 1 PRINTS 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMR 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 1227
  • Mass: 142577
  • Checksum: 497CC1C4B258515C
  • Sequence:
    • MTTHVTLEDA LSNVDLLEEL PLPDQQPCIE PPPSSIMYQA NFDTNFEDRN AFVTGIARYI 
EQATVHSSMV KCNEQPNRVE IYEKTVEVLE PEVTKLMKFM YFQRKAIERF CSEVKRLCHA 
ERRKDFVSEA YLLTLGKFIN MFAVLDELKN MKCSVKNDHS AYKRAAQFLR KMADPQSIQE 
SQNLSMFLAN HNRITQCLHQ QLEVIPGYEE LLADIVNICV DYYENKMYLT PSEKHMLLKV 
MGFGLYLMDG NVSNIYKLDA KKRINLSKID KFFKQLQVVP LFGDMQIELA RYIKTSAHYE 
ENKSKWTCTQ SSISPQYNIC EQMVQIRDDH IRFISELARY SNSEVVTGSG LDSQKSDEEY 
RELFDLALRG LQLLSKWSAH VMEVYSWKLV HPTDKFCNKD CPGTAEEYER ATRYNYTSEE 
KFAFVEVIAM IKGLQVLMGR MESVFNQAIR NTIYAALQDF AQVTLREPLR QAVRKKKNVL 
ISVLQAIRKT ICDWEGGREP PNDPCLRGEK DPKGGFDIKV PRRAVGPSST QLYMVRTMLE 
SLIADKSGSK KTLRSSLDGP IVLAIEDFHK QSFFFTHLLN ISEALQQCCD LSQLWFREFF 
LELTMGRRIQ FPIEMSMPWI LTDHILETKE PSMMEYVLYP LDLYNDSAYY ALTKFKKQFL 
YDEIEAEVNL CFDQFVYKLA DQIFAYYKAM AGSVLLDKRF RAECKNYGVI IPYPPSNRYE 
TLLKQRHVQL LGRSIDLNRL ITQRISAAMY KSLDQAISRF ESEDLTSIVE LEWLLEINRL 
THRLLCKHMT LDSFDAMFRE ANHNVSAPYG RITLHVFWEL NFDFLPNYCY NGSTNRFVRT 
AIPFTQEPQR DKPANVQPYY LYGSKPLNIA YSHIYSSYRN FVGPPHFKTI CRLLGYQGIA 
VVMEELLKIV KSLLQGTILQ YVKTLIEVMP KICRLPRHEY GSPGILEFFH HQLKDIIEYA 
ELKTDVFQSL REVGNAILFC LLIEQALSQE EVCDLLHAAP FQNILPRVYI KEGERLEVRM 
KRLEAKYAPL HLVPLIERLG TPQQIAIARE GDLLTKERLC CGLSMFEVIL TRIRSYLQDP 
IWRGPPPTNG VMHVDECVEF HRLWSAMQFV YCIPVGTNEF TAEQCFGDGL NWAGCSIIVL 
LGQQRRFDLF DFCYHLLKVQ RQDGKDEIIK NVPLKKMADR IRKYQILNNE VFAILNKYMK 
SVETDSSTVE HVRCFQPPIH QSLATTC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.