Details for: IMPDH2

Gene ID: 3615

Symbol: IMPDH2

Ensembl ID: ENSG00000178035

Description: inosine monophosphate dehydrogenase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 226.4293
    Cell Significance Index: -35.2200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 111.7011
    Cell Significance Index: -46.0200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 101.6050
    Cell Significance Index: -47.9700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 100.4167
    Cell Significance Index: -40.8000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 93.0237
    Cell Significance Index: -47.8500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 71.6668
    Cell Significance Index: -48.0900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 46.9163
    Cell Significance Index: -11.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 43.4672
    Cell Significance Index: -41.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.7028
    Cell Significance Index: -44.0200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.2523
    Cell Significance Index: -38.1800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.8980
    Cell Significance Index: -46.9500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.9290
    Cell Significance Index: -27.4300
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 8.3484
    Cell Significance Index: 106.9200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 7.0522
    Cell Significance Index: 821.8500
  • Cell Name: theca cell (CL0000503)
    Fold Change: 6.9378
    Cell Significance Index: 40.7600
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 6.3534
    Cell Significance Index: 69.0700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 5.8861
    Cell Significance Index: 157.4500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.8460
    Cell Significance Index: 335.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 4.1898
    Cell Significance Index: 87.7000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 4.0707
    Cell Significance Index: 525.9100
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 3.5595
    Cell Significance Index: 28.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.8575
    Cell Significance Index: 392.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.6851
    Cell Significance Index: 189.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.4325
    Cell Significance Index: 66.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.2568
    Cell Significance Index: 145.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 2.2392
    Cell Significance Index: 105.2400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.0126
    Cell Significance Index: 150.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.0046
    Cell Significance Index: 1094.7700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.9668
    Cell Significance Index: 45.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.9386
    Cell Significance Index: 1750.4500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.8021
    Cell Significance Index: 221.5900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.7899
    Cell Significance Index: 92.9800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 1.6977
    Cell Significance Index: 200.2100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.6087
    Cell Significance Index: 42.3000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.5767
    Cell Significance Index: 269.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.5511
    Cell Significance Index: 53.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5482
    Cell Significance Index: 279.1000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 1.5252
    Cell Significance Index: 674.3200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.4834
    Cell Significance Index: 13.6600
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 1.3885
    Cell Significance Index: 8.5900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.3714
    Cell Significance Index: 15.5800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.1578
    Cell Significance Index: 20.4600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.1396
    Cell Significance Index: 32.8400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.0432
    Cell Significance Index: 48.6400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.0038
    Cell Significance Index: 29.4800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.9054
    Cell Significance Index: 116.0700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8232
    Cell Significance Index: 37.3200
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.8019
    Cell Significance Index: 6.0600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7505
    Cell Significance Index: 16.2600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.5021
    Cell Significance Index: 3.0900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4764
    Cell Significance Index: 13.6600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.4337
    Cell Significance Index: 11.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3737
    Cell Significance Index: 74.1700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3491
    Cell Significance Index: 11.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2728
    Cell Significance Index: 51.9100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2569
    Cell Significance Index: 7.1800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.2235
    Cell Significance Index: 3.7400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1525
    Cell Significance Index: 5.3600
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.1294
    Cell Significance Index: 0.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1268
    Cell Significance Index: 95.9400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.1232
    Cell Significance Index: 76.9400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0680
    Cell Significance Index: 3.5400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0550
    Cell Significance Index: 5.4400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0212
    Cell Significance Index: 14.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0120
    Cell Significance Index: 1.9600
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.0108
    Cell Significance Index: -0.0500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0137
    Cell Significance Index: -0.3500
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: -0.0175
    Cell Significance Index: -0.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0181
    Cell Significance Index: -34.1500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0209
    Cell Significance Index: -2.1400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0213
    Cell Significance Index: -15.6400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0215
    Cell Significance Index: -15.9400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0244
    Cell Significance Index: -8.7600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0285
    Cell Significance Index: -52.4700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0312
    Cell Significance Index: -6.2600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0349
    Cell Significance Index: -53.7000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0421
    Cell Significance Index: -57.2900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0597
    Cell Significance Index: -33.6600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0630
    Cell Significance Index: -40.0100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.0631
    Cell Significance Index: -0.6700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0651
    Cell Significance Index: -3.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0886
    Cell Significance Index: -2.3700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0994
    Cell Significance Index: -45.1300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1239
    Cell Significance Index: -14.1900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1255
    Cell Significance Index: -26.4400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1385
    Cell Significance Index: -39.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1796
    Cell Significance Index: -4.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2548
    Cell Significance Index: -13.3800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2888
    Cell Significance Index: -2.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2950
    Cell Significance Index: -42.8800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.3149
    Cell Significance Index: -35.9500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3459
    Cell Significance Index: -2.0900
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.3640
    Cell Significance Index: -3.8000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3907
    Cell Significance Index: -5.3300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3994
    Cell Significance Index: -24.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4245
    Cell Significance Index: -23.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4484
    Cell Significance Index: -46.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4597
    Cell Significance Index: -36.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5131
    Cell Significance Index: -32.3400
  • Cell Name: chondroblast (CL0000058)
    Fold Change: -0.5554
    Cell Significance Index: -3.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IMPDH2 is a bifunctional enzyme that catalyzes the conversion of inosine monophosphate (IMP) to xanthosine-5'-monophosphate (XMP) and guanosine-5'-monophosphate (GMP). This reaction is a rate-limiting step in the de novo biosynthesis of guanosine nucleotides. IMPDH2 is composed of two subunits, which are encoded by separate genes. The human IMPDH2 gene (IMPDH2) is located on chromosome 22q13.32. **Pathways and Functions** IMPDH2 is involved in several critical pathways, including: 1. **Purine biosynthesis**: IMPDH2 is a key enzyme in the de novo biosynthesis of guanosine nucleotides, which are essential for RNA and DNA synthesis. 2. **Cell growth and proliferation**: IMPDH2 regulates cell growth and proliferation by controlling the availability of guanosine nucleotides. 3. **Immune response**: IMPDH2 is highly expressed in immune cells, such as T cells and B cells, and plays a crucial role in the regulation of immune responses. 4. **Antiviral responses**: IMPDH2 has been implicated in the antiviral response to viral infections, including HIV and SARS-CoV. **Clinical Significance** IMPDH2 has been implicated in several diseases, including: 1. **Cancer**: IMPDH2 overexpression has been observed in various types of cancer, including leukemia, lymphoma, and solid tumors. 2. **Autoimmune disorders**: IMPDH2 has been implicated in autoimmune disorders, such as rheumatoid arthritis and lupus. 3. **Viral infections**: IMPDH2 has been shown to play a role in the antiviral response to viral infections, including HIV and SARS-CoV. 4. **Neurodegenerative diseases**: IMPDH2 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In conclusion, IMPDH2 is a critical enzyme involved in the biosynthesis of guanosine nucleotides and plays a pivotal role in regulating cell growth, proliferation, and differentiation. Its dysregulation has been implicated in various diseases, making it an attractive target for the development of therapeutic agents. As an expert immunologist, I emphasize the importance of understanding the complex role of IMPDH2 in the immune system and its potential applications in the treatment of various diseases.

Genular Protein ID: 1852624224

Symbol: IMDH2_HUMAN

Name: N/A

UniProtKB Accession Codes:

P12268 Q6LEF3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 20 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 10 DrugCentral 1 EC 1 EMBL 7 EMDB 17 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HAMAP 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 2 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 22 PDBsum 22 PIR 1 PIRSF 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 REPRODUCTION-2DPAGE 2 RNAct 1 Reactome 4 RefSeq 1 Rhea 1 SABIO-RK 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2902093

Title: Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.

PubMed ID: 2902093

DOI: 10.1016/s0021-9258(19)37654-9

PubMed ID: 1969416

Title: Two distinct cDNAs for human IMP dehydrogenase.

PubMed ID: 1969416

DOI: 10.1016/s0021-9258(19)34120-1

PubMed ID: 7999076

Title: Cloning and sequence of the human type II IMP dehydrogenase gene.

PubMed ID: 7999076

DOI: 10.1006/bbrc.1994.2698

PubMed ID: 7896827

Title: Characterization of the human inosine-5'-monophosphate dehydrogenase type II gene.

PubMed ID: 7896827

DOI: 10.1074/jbc.270.12.6808

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8098009

Title: Chromosomal localization and structure of the human type II IMP dehydrogenase gene.

PubMed ID: 8098009

DOI: 10.1006/geno.1993.1177

PubMed ID: 7903306

Title: Characterization of human type I and type II IMP dehydrogenases.

PubMed ID: 7903306

DOI: 10.1016/s0021-9258(19)74247-1

PubMed ID: 7763314

Title: Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.

PubMed ID: 7763314

DOI: 10.1016/0006-2952(95)00026-v

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 14766016

Title: Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.

PubMed ID: 14766016

DOI: 10.1042/bj20031585

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17496727

Title: A novel variant L263F in human inosine 5'-monophosphate dehydrogenase 2 is associated with diminished enzyme activity.

PubMed ID: 17496727

DOI: 10.1097/fpc.0b013e328012b8cf

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28985504

Title: CLOCK acetylates ASS1 to drive circadian rhythm of ureagenesis.

PubMed ID: 28985504

DOI: 10.1016/j.molcel.2017.09.008

PubMed ID: 24477477

Title: Glutamine deprivation initiates reversible assembly of mammalian rods and rings.

PubMed ID: 24477477

DOI: 10.1007/s00018-014-1567-6

PubMed ID: 30293565

Title: ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase.

PubMed ID: 30293565

DOI: 10.1016/j.bbadis.2018.07.001

PubMed ID: 31337707

Title: ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly.

PubMed ID: 31337707

DOI: 10.1074/jbc.ra119.008231

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 10097070

Title: Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.

PubMed ID: 10097070

DOI: 10.1073/pnas.96.7.3531

Sequence Information:

  • Length: 514
  • Mass: 55805
  • Checksum: 876BEA0EC1DDBEE9
  • Sequence:
    • MADYLISGGT SYVPDDGLTA QQLFNCGDGL TYNDFLILPG YIDFTADQVD LTSALTKKIT 
LKTPLVSSPM DTVTEAGMAI AMALTGGIGF IHHNCTPEFQ ANEVRKVKKY EQGFITDPVV 
LSPKDRVRDV FEAKARHGFC GIPITDTGRM GSRLVGIISS RDIDFLKEEE HDCFLEEIMT 
KREDLVVAPA GITLKEANEI LQRSKKGKLP IVNEDDELVA IIARTDLKKN RDYPLASKDA 
KKQLLCGAAI GTHEDDKYRL DLLAQAGVDV VVLDSSQGNS IFQINMIKYI KDKYPNLQVI 
GGNVVTAAQA KNLIDAGVDA LRVGMGSGSI CITQEVLACG RPQATAVYKV SEYARRFGVP 
VIADGGIQNV GHIAKALALG ASTVMMGSLL AATTEAPGEY FFSDGIRLKK YRGMGSLDAM 
DKHLSSQNRY FSEADKIKVA QGVSGAVQDK GSIHKFVPYL IAGIQHSCQD IGAKSLTQVR 
AMMYSGELKF EKRTSSAQVE GGVHSLHSYE KRLF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.