Details for: POLD4

Gene ID: 57804

Symbol: POLD4

Ensembl ID: ENSG00000175482

Description: DNA polymerase delta 4, accessory subunit

Associated with

Other Information

Genular Protein ID: 172742314

Symbol: DPOD4_HUMAN

Name: DNA polymerase delta subunit 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10751307

Title: Identification of a fourth subunit of mammalian DNA polymerase delta.

PubMed ID: 10751307

DOI: 10.1074/jbc.m001217200

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12403614

Title: Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme.

PubMed ID: 12403614

DOI: 10.1021/bi0262707

PubMed ID: 12522211

Title: Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen.

PubMed ID: 12522211

DOI: 10.1074/jbc.m208694200

PubMed ID: 15670210

Title: Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.

PubMed ID: 15670210

DOI: 10.1111/j.1365-2443.2004.00812.x

PubMed ID: 16934752

Title: The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins.

PubMed ID: 16934752

DOI: 10.1016/j.bbrc.2006.08.049

PubMed ID: 16510448

Title: Functional roles of p12, the fourth subunit of human DNA polymerase delta.

PubMed ID: 16510448

DOI: 10.1074/jbc.m600322200

PubMed ID: 17317665

Title: A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta.

PubMed ID: 17317665

DOI: 10.1074/jbc.m610356200

PubMed ID: 19074196

Title: DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers.

PubMed ID: 19074196

DOI: 10.1093/nar/gkn1000

PubMed ID: 20334433

Title: The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis.

PubMed ID: 20334433

DOI: 10.1021/bi100042b

PubMed ID: 22801543

Title: Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage.

PubMed ID: 22801543

DOI: 10.4161/cc.21280

PubMed ID: 24035200

Title: Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase delta.

PubMed ID: 24035200

DOI: 10.1016/j.dnarep.2013.08.008

PubMed ID: 23233665

Title: Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase delta for degradation in response to DNA damage.

PubMed ID: 23233665

DOI: 10.1074/jbc.m112.423392

PubMed ID: 23913683

Title: A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase delta in response to DNA damage and during the S phase.

PubMed ID: 23913683

DOI: 10.1074/jbc.m113.490466

PubMed ID: 24022480

Title: Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage.

PubMed ID: 24022480

DOI: 10.1074/jbc.c113.505586

PubMed ID: 24300032

Title: The tail that wags the dog: p12, the smallest subunit of DNA polymerase delta, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression.

PubMed ID: 24300032

DOI: 10.4161/cc.27407

PubMed ID: 24310611

Title: Break-induced replication repair of damaged forks induces genomic duplications in human cells.

PubMed ID: 24310611

DOI: 10.1126/science.1243211

Sequence Information:

  • Length: 107
  • Mass: 12433
  • Checksum: 6F412738E4D9A19C
  • Sequence:
  • MGRKRLITDS YPVVKRREGP AGHSKGELAP ELGEEPQPRD EEEAELELLR QFDLAWQYGP 
    CTGITRLQRW CRAKQMGLEP PPEVWQVLKT HPGDPRFQCS LWHLYPL

Genular Protein ID: 2308432971

Symbol: Q6NSD7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 107
  • Mass: 12442
  • Checksum: 79034308E4D9A19C
  • Sequence:
  • MGRKRLITDS YPVVKRREGP AGHSKGELAP ELGEEPQPRD EEEAELELLR QFDLAWQYGP 
    CTGITRLQRW CRAKHMGLEP PPEVWQVLKT HPGDPRFQCS LWHLYPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.