Cell ID: CL0000767

Cell Name: basophil

CSI Thresholds:

Select	Context	Threshold
	Overall	9.2022
	Blood	25.7902
	Liver + Healthy	12.1395
	Liver	9.7363
	Bone marrow + Healthy	9.3292
	Blood + Healthy	8.4764
	Lung	7.4476
	Healthy	7.4367
	Bone marrow	4.5127
	Lung + Healthy	3.5168

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(Cell Significance Index is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers.)

Description: Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.

Synonyms: polymorphonuclear leucocyte, polymorphonuclear leukocyte, basophilic leucocyte, basophilic leukocyte