Details for: ASAH1

Gene ID: 427

Symbol: ASAH1

Ensembl ID: ENSG00000104763

Description: N-acylsphingosine amidohydrolase 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 5.17
    Marker Score: 4049
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.43
    Marker Score: 8642
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 3.41
    Marker Score: 190659
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 3.3
    Marker Score: 7964
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 3.27
    Marker Score: 73010
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 3.18
    Marker Score: 20734
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 3.05
    Marker Score: 5944
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 2.97
    Marker Score: 3582
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.93
    Marker Score: 2928
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.87
    Marker Score: 73429
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 2.78
    Marker Score: 5065.5
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 2.75
    Marker Score: 14432
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.72
    Marker Score: 4369
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2.67
    Marker Score: 3703
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 2.57
    Marker Score: 6390
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.53
    Marker Score: 2889.5
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 2.48
    Marker Score: 1692
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.45
    Marker Score: 10192
  • Cell Name: basophil (CL0000767)
    Fold Change: 2.41
    Marker Score: 1143
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.39
    Marker Score: 27789
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.35
    Marker Score: 4776
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.35
    Marker Score: 3459
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.32
    Marker Score: 3286
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.32
    Marker Score: 1548
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 2.31
    Marker Score: 1037
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 2.28
    Marker Score: 658
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 2.27
    Marker Score: 13795.5
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 2.26
    Marker Score: 943
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 2.26
    Marker Score: 3592
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.25
    Marker Score: 918
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 2.23
    Marker Score: 19224
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 2.21
    Marker Score: 1218
  • Cell Name: club cell (CL0000158)
    Fold Change: 2.2
    Marker Score: 2563
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 2.18
    Marker Score: 977
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.16
    Marker Score: 5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.15
    Marker Score: 8308
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 2.15
    Marker Score: 1530
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.14
    Marker Score: 34300
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 2.14
    Marker Score: 2578
  • Cell Name: tracheobronchial goblet cell (CL0019003)
    Fold Change: 2.12
    Marker Score: 580
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.09
    Marker Score: 3467
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.08
    Marker Score: 7392
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: 2.06
    Marker Score: 1291
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.98
    Marker Score: 1092
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.96
    Marker Score: 68064
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 1.95
    Marker Score: 1191
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.95
    Marker Score: 3557.5
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.95
    Marker Score: 1979
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.94
    Marker Score: 7636
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 1.93
    Marker Score: 1725
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.93
    Marker Score: 1841
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.92
    Marker Score: 14306
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.92
    Marker Score: 2313
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.91
    Marker Score: 2007
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.91
    Marker Score: 1110
  • Cell Name: platelet (CL0000233)
    Fold Change: 1.9
    Marker Score: 858
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 1.89
    Marker Score: 1786
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 1.89
    Marker Score: 705
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.88
    Marker Score: 992
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.88
    Marker Score: 760
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 1.87
    Marker Score: 782
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.86
    Marker Score: 6618
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.85
    Marker Score: 1999
  • Cell Name: glandular cell of esophagus (CL0002657)
    Fold Change: 1.85
    Marker Score: 585
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.81
    Marker Score: 1206.5
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.81
    Marker Score: 7577.5
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 1.8
    Marker Score: 4670
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.8
    Marker Score: 429
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.79
    Marker Score: 1902
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.78
    Marker Score: 13938
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 1.78
    Marker Score: 844
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 1.77
    Marker Score: 872
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.76
    Marker Score: 1862
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.76
    Marker Score: 1173
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.76
    Marker Score: 344
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.74
    Marker Score: 815
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 1.73
    Marker Score: 525
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.72
    Marker Score: 14985
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 1.72
    Marker Score: 579
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.72
    Marker Score: 1244
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.72
    Marker Score: 1784
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 1.71
    Marker Score: 913
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.7
    Marker Score: 3869
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: 1.68
    Marker Score: 669
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.68
    Marker Score: 724
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.67
    Marker Score: 537
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.66
    Marker Score: 534
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 1.66
    Marker Score: 1140
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.64
    Marker Score: 6857
  • Cell Name: ventricular cardiac muscle cell (CL2000046)
    Fold Change: 1.64
    Marker Score: 680
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.64
    Marker Score: 384
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 1.63
    Marker Score: 1365
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 1.63
    Marker Score: 658
  • Cell Name: macrophage (CL0000235)
    Fold Change: 1.63
    Marker Score: 1815
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.63
    Marker Score: 952.5
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.63
    Marker Score: 3695
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 1.62
    Marker Score: 362
  • Cell Name: stem cell (CL0000034)
    Fold Change: 1.62
    Marker Score: 3846
  • Cell Name: monocyte (CL0000576)
    Fold Change: 1.61
    Marker Score: 2095
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.61
    Marker Score: 813

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Other Information

**Key characteristics:** - Gene name: ASAH1 - Ensembl ID: ENSG00000104763 - Protein name: N-acylsphingosine amidohydrolase 1 - Protein function: Ceramide biosynthetic process, immune system, Keratinocyte differentiation, Metabolism, Metabolism of lipids **Pathways and functions:** - Ceramidase activity: ASAH1 is a ceramidase enzyme, which catalyzes the hydrolysis of ceramide molecules to produce sphingosine. - Ceramide biosynthetic process: ASAH1 is involved in the synthesis of ceramide from precursors such as sphingomyelin, a precursor molecule. - Fatty acid amide hydrolase activity: ASAH1 also has a fatty acid amide hydrolase activity, which may be involved in the metabolism of other lipids. - Fatty acid metabolic process: ASAH1 is involved in the metabolism of fatty acids, as it can hydrolyze fatty acids to produce free fatty acids and hydrogen ions. - Glycosphingolipid catabolism: ASAH1 can also participate in the catabolism of glycosphingolipids, a class of lipids that are derived from the breakdown of phospholipids. - Glycosphingolipid metabolism: ASAH1 is involved in the metabolism of glycosphingolipids, including the synthesis of ceramide from sphingosine. - Hydrolase activity: ASAH1 is a hydrolase enzyme, which means that it can break hydrogen bonds between molecules. In this context, ASAH1 can hydrolyze carbon-nitrogen (but not peptide) bonds in linear amides. - Acting on carbon-nitrogen (but not peptide) bonds: ASAH1 can act on carbon-nitrogen (but not peptide) bonds in linear amides, indicating its involvement in the metabolism of ceramide and other lipid molecules. **Clinical significance:** - ASAH1 gene is significantly expressed in cells of the immune system, including thyroid follicular cell, kidney collecting duct principal cell, monocyte subsets, and macrophages. - Mutations in the ASAH1 gene have been linked to several human diseases, including autoimmune disorders and cancer. - ASAH1 inhibitors are being investigated as potential therapeutic agents for these diseases.

Genular Protein ID: 875613905

Symbol: ASAH1_HUMAN

Name: Acylsphingosine deacylase

UniProtKB Accession Codes:

Q13510 E9PDS0 Q6W898 Q96AS2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEBI 48 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 9 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 22 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MEROPS 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 2 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 Rhea 25 SABIO-RK 1 SMR 1 STRING 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8955159

Title: Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease.

PubMed ID: 8955159

DOI: 10.1074/jbc.271.51.33110

PubMed ID: 10993717

Title: Human acid ceramidase gene: novel mutations in Farber disease.

PubMed ID: 10993717

DOI: 10.1006/mgme.2000.3029

PubMed ID: 10610716

Title: The human acid ceramidase gene (ASAH): structure, chromosomal location, mutation analysis, and expression.

PubMed ID: 10610716

DOI: 10.1006/geno.1999.5940

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7744740

Title: Purification, characterization, and biosynthesis of human acid ceramidase.

PubMed ID: 7744740

DOI: 10.1074/jbc.270.19.11098

PubMed ID: 11451951

Title: Human acid ceramidase: processing, glycosylation, and lysosomal targeting.

PubMed ID: 11451951

DOI: 10.1074/jbc.m103066200

PubMed ID: 12764132

Title: The reverse activity of human acid ceramidase.

PubMed ID: 12764132

DOI: 10.1074/jbc.m303310200

PubMed ID: 12815059

Title: Purification and characterization of recombinant, human acid ceramidase. Catalytic reactions and interactions with acid sphingomyelinase.

PubMed ID: 12815059

DOI: 10.1074/jbc.m301936200

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 15655246

Title: Molecular characterization of N-acylethanolamine-hydrolyzing acid amidase, a novel member of the choloylglycine hydrolase family with structural and functional similarity to acid ceramidase.

PubMed ID: 15655246

DOI: 10.1074/jbc.m413473200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16263699

Title: Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

PubMed ID: 16263699

DOI: 10.1074/mcp.m500324-mcp200

PubMed ID: 17713573

Title: Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes.

PubMed ID: 17713573

DOI: 10.1038/sj.jid.5701025

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22927646

Title: Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor.

PubMed ID: 22927646

DOI: 10.1128/mcb.00378-12

PubMed ID: 22261821

Title: Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression.

PubMed ID: 22261821

DOI: 10.1210/me.2011-1150

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 30525581

Title: Molecular mechanism of inhibition of acid ceramidase by carmofur.

PubMed ID: 30525581

DOI: 10.1021/acs.jmedchem.8b01723

PubMed ID: 29692406

Title: Structural basis for the activation of acid ceramidase.

PubMed ID: 29692406

DOI: 10.1038/s41467-018-03844-2

PubMed ID: 11241842

Title: Molecular analysis of acid ceramidase deficiency in patients with Farber disease.

PubMed ID: 11241842

DOI: 10.1002/humu.5

PubMed ID: 12638942

Title: Mutation analysis of the acid ceramidase gene in Japanese patients with Farber disease.

PubMed ID: 12638942

DOI: 10.1023/a:1022047408477

PubMed ID: 16951918

Title: Farber lipogranulomatosis: clinical and molecular genetic analysis reveals a novel mutation in an Indian family.

PubMed ID: 16951918

DOI: 10.1007/s10038-006-0019-z

PubMed ID: 20609603

Title: Farber lipogranulomatosis type 1--late presentation and early death in a Croatian boy with a novel homozygous ASAH1 mutation.

PubMed ID: 20609603

DOI: 10.1016/j.ejpn.2010.06.002

PubMed ID: 22703880

Title: Spinal muscular atrophy associated with progressive myoclonic epilepsy is caused by mutations in ASAH1.

PubMed ID: 22703880

DOI: 10.1016/j.ajhg.2012.05.001

PubMed ID: 21893389

Title: Novel V97G ASAH1 mutation found in Farber disease patients: unique appearance of the disease with an intermediate severity, and marked early involvement of central and peripheral nervous system.

PubMed ID: 21893389

DOI: 10.1016/j.braindev.2011.07.003

PubMed ID: 21982811

Title: A novel mutation in an atypical presentation of the rare infantile Farber disease.

PubMed ID: 21982811

DOI: 10.1016/j.braindev.2011.09.006

PubMed ID: 24164096

Title: Evidence for clinical, genetic and biochemical variability in spinal muscular atrophy with progressive myoclonic epilepsy.

PubMed ID: 24164096

DOI: 10.1111/cge.12307

PubMed ID: 27411168

Title: Atypical presentation of infantile-onset farber disease with novel ASAH1 mutations.

PubMed ID: 27411168

DOI: 10.1002/ajmg.a.37846

PubMed ID: 26945816

Title: Brief Report: Peripheral Osteolysis in Adults Linked to ASAH1 (Acid Ceramidase) Mutations: A New Presentation of Farber's Disease.

PubMed ID: 26945816

DOI: 10.1002/art.39659

PubMed ID: 27026573

Title: ASAH1 variant causing a mild SMA phenotype with no myoclonic epilepsy: a clinical, biochemical and molecular study.

PubMed ID: 27026573

DOI: 10.1038/ejhg.2016.28

PubMed ID: 33798445

Title: Progressive myoclonus epilepsies-Residual unsolved cases have marked genetic heterogeneity including dolichol-dependent protein glycosylation pathway genes.

PubMed ID: 33798445

DOI: 10.1016/j.ajhg.2021.03.013

Sequence Information:

  • Length: 395
  • Mass: 44660
  • Checksum: 83467DBE8917DB6D
  • Sequence:
    • MPGRSCVALV LLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY TINLDLPPYK 
RWHELMLDKA PVLKVIVNSL KNMINTFVPS GKIMQVVDEK LPGLLGNFPG PFEEEMKGIA 
AVTDIPLGEI ISFNIFYELF TICTSIVAED KKGHLIHGRN MDFGVFLGWN INNDTWVITE 
QLKPLTVNLD FQRNNKTVFK ASSFAGYVGM LTGFKPGLFS LTLNERFSIN GGYLGILEWI 
LGKKDVMWIG FLTRTVLENS TSYEEAKNLL TKTKILAPAY FILGGNQSGE GCVITRDRKE 
SLDVYELDAK QGRWYVVQTN YDRWKHPFFL DDRRTPAKMC LNRTSQENIS FETMYDVLST 
KPVLNKLTVY TTLIDVTKGQ FETYLRDCPD PCIGW

Genular Protein ID: 1185543240

Symbol: Q53H01_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53H01

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 EC 1 EMBL 2 GO 5 Genevisible 1 GenomeRNAi 1 InterPro 3 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PROSITE 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 3 Rhea 1 SAM 1 SMR 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 395
  • Mass: 44692
  • Checksum: A20FCC0E1B139F72
  • Sequence:
    • MPGRSCVALV LLAVAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY TINLDLPPYK 
RWHELMLDKA PMLKVIVNSL KNMINTFVPS GKVMQVVDEK LPGLLGNFPG PFEEEMKGIA 
AVTDIPLGEI ISFNIFYELF TICTSIVAED KKGHLIHGRN MDFGVFLGWN INNDTWVITE 
QLRPLTVNLD FQRNNKTVFK ASSFAGYVGM LTGFKPGLFS LTLNERFSIN GGYLGILEWI 
LGKKDAMWIG FLTRTVLENS TSYEEAKNLL TKTKILAPAY FVLGGNQSGE GCVITRDRKE 
SLDVYELDAK QGRWYVVQTN YDRWKHPFFL DDRRTPAKMC LNRTSQENIS FETMYDVLST 
KPVLNKLTVY TTLIDVTKGQ FETYLRDCPD PCIGW

Genular Protein ID: 2273286424

Symbol: A8K0B6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K0B6

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 4 DNASU 1 EC 1 EMBL 2 GO 5 Genevisible 1 GenomeRNAi 1 InterPro 3 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PROSITE 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 3 Rhea 1 SAM 1 SMR 1

Sequence Information:

  • Length: 395
  • Mass: 44674
  • Checksum: CC66BC47663C0351
  • Sequence:
    • MPGRSCVALV HLAAAVSCAV AQHAPPWTED CRKSTYPPSG PTYRGAVPWY TINLDLPPYK 
RWHELMLDKA PMLKVIVNSL KNMINTFVPS GKVMQVVDEK LPGLLGNFPG PFEEEMKGIA 
AVTDIPLGEI ISFNIFYELF TICTSIVAED KKGHLIHGRN MDFGVFLGWN INNDTWVITE 
QLKPLTVNLD FQRNNKTVFK ASSFAGYVGM LTGFKPGLFS LTLNERFSIN GGYLGILEWI 
LGKKDAMWIG FLTRTVLENS TSYEEAKNLL TKTKILAPAY FILGGNQSGE GCVITRDRKE 
SLDVYELDAK QGRWYVVQTN YDRWKHPFFL DDRRTPAKMC LNRTSQENIS FETMYDVLST 
KPVLNKLTVY TTLIDVTKGQ FETYLRDCPD PCIGW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.