Details for: CAPZA2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
Fold Change: 3.41
Marker Score: 4,932 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: 2.94
Marker Score: 3,547 - Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 2.8
Marker Score: 7,108 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 2.76
Marker Score: 2,379 - Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 2.62
Marker Score: 1,642 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 2.5
Marker Score: 4,984 - Cell Name: lung macrophage (CL1001603)
Fold Change: 2.49
Marker Score: 2,850 - Cell Name: supporting cell (CL0000630)
Fold Change: 2.44
Marker Score: 4,578 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 2.43
Marker Score: 136,103 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.42
Marker Score: 3,522 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: 2.38
Marker Score: 60,990 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.37
Marker Score: 5,780 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 2.33
Marker Score: 3,033 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.31
Marker Score: 78,597 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.3
Marker Score: 9,935 - Cell Name: erythroblast (CL0000765)
Fold Change: 2.27
Marker Score: 1,420 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 2.26
Marker Score: 8,028 - Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.25
Marker Score: 3,727 - Cell Name: eurydendroid cell (CL0000253)
Fold Change: 2.24
Marker Score: 916 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.24
Marker Score: 77,542 - Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 2.22
Marker Score: 4,328 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 2.22
Marker Score: 5,948 - Cell Name: non-classical monocyte (CL0000875)
Fold Change: 2.21
Marker Score: 5,331 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.21
Marker Score: 4,607 - Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 2.18
Marker Score: 5,493 - Cell Name: Kupffer cell (CL0000091)
Fold Change: 2.16
Marker Score: 2,165 - Cell Name: blood cell (CL0000081)
Fold Change: 2.15
Marker Score: 25,037 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 2.15
Marker Score: 2,315 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.15
Marker Score: 18,527 - Cell Name: kidney cell (CL1000497)
Fold Change: 2.14
Marker Score: 1,429 - Cell Name: ependymal cell (CL0000065)
Fold Change: 2.12
Marker Score: 740 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 2.12
Marker Score: 4,307 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 2.12
Marker Score: 1,669 - Cell Name: endothelial cell (CL0000115)
Fold Change: 2.12
Marker Score: 1,898 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 2.1
Marker Score: 1,154 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 2.08
Marker Score: 868 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.07
Marker Score: 495 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 2.07
Marker Score: 2,206 - Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 2.07
Marker Score: 2,095 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 2.06
Marker Score: 699 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.05
Marker Score: 45,853 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 2.04
Marker Score: 1,052 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.04
Marker Score: 4,804 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 2.03
Marker Score: 3,444 - Cell Name: platelet (CL0000233)
Fold Change: 2.03
Marker Score: 920 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 2.03
Marker Score: 2,147 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2
Marker Score: 3,401 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.97
Marker Score: 12,567 - Cell Name: endothelial cell of artery (CL1000413)
Fold Change: 1.97
Marker Score: 816 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 1.96
Marker Score: 1,846 - Cell Name: Bergmann glial cell (CL0000644)
Fold Change: 1.96
Marker Score: 797 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.95
Marker Score: 2,359 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.95
Marker Score: 7,503 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 1.94
Marker Score: 736 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.94
Marker Score: 4,265 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.94
Marker Score: 4,833 - Cell Name: secretory cell (CL0000151)
Fold Change: 1.91
Marker Score: 3,489 - Cell Name: smooth muscle cell (CL0000192)
Fold Change: 1.91
Marker Score: 1,255 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.9
Marker Score: 2,136 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: 1.9
Marker Score: 1,985 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.9
Marker Score: 7,458 - Cell Name: enterocyte (CL0000584)
Fold Change: 1.89
Marker Score: 9,070 - Cell Name: club cell (CL0000158)
Fold Change: 1.88
Marker Score: 2,198 - Cell Name: Mueller cell (CL0000636)
Fold Change: 1.88
Marker Score: 2,606 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 1.87
Marker Score: 1,692 - Cell Name: microglial cell (CL0000129)
Fold Change: 1.87
Marker Score: 3,403 - Cell Name: epithelial cell (CL0000066)
Fold Change: 1.86
Marker Score: 2,960 - Cell Name: neutrophil (CL0000775)
Fold Change: 1.85
Marker Score: 1,127 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: 1.85
Marker Score: 1,229 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 1.84
Marker Score: 1,759 - Cell Name: granulocyte (CL0000094)
Fold Change: 1.84
Marker Score: 825 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 1.84
Marker Score: 1,307 - Cell Name: basophil (CL0000767)
Fold Change: 1.83
Marker Score: 870 - Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.82
Marker Score: 1,932 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.82
Marker Score: 1,715 - Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 1.82
Marker Score: 1,958 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 1.81
Marker Score: 3,210 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.81
Marker Score: 2,664 - Cell Name: stromal cell (CL0000499)
Fold Change: 1.81
Marker Score: 2,117 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.79
Marker Score: 945 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 1.79
Marker Score: 576 - Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 1.79
Marker Score: 2,538 - Cell Name: muscle cell (CL0000187)
Fold Change: 1.79
Marker Score: 507 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 1.77
Marker Score: 1,055 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 1.75
Marker Score: 5,509 - Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 1.75
Marker Score: 410 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.75
Marker Score: 869 - Cell Name: podocyte (CL0000653)
Fold Change: 1.74
Marker Score: 642 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.73
Marker Score: 699 - Cell Name: fibroblast (CL0000057)
Fold Change: 1.73
Marker Score: 1,674 - Cell Name: fetal cardiomyocyte (CL0002495)
Fold Change: 1.73
Marker Score: 570 - Cell Name: small pre-B-II cell (CL0000954)
Fold Change: 1.73
Marker Score: 2,080 - Cell Name: melanocyte (CL0000148)
Fold Change: 1.73
Marker Score: 701 - Cell Name: hepatocyte (CL0000182)
Fold Change: 1.73
Marker Score: 1,179 - Cell Name: elicited macrophage (CL0000861)
Fold Change: 1.73
Marker Score: 10,493 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 1.73
Marker Score: 2,131 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: 1.73
Marker Score: 367 - Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
Fold Change: 1.72
Marker Score: 841 - Cell Name: decidual natural killer cell, human (CL0002343)
Fold Change: 1.72
Marker Score: 4,758 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.72
Marker Score: 3,898
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 53438944
Symbol: CAZA2_HUMAN
Name: F-actin-capping protein subunit alpha-2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7665558
Title: Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families.
PubMed ID: 7665558
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9331217
Title: Vertebrates have conserved capping protein alpha isoforms with specific expression patterns.
PubMed ID: 9331217
DOI: 10.1002/(sici)1097-0169(1997)38:2<120::aid-cm2>3.0.co;2-b
PubMed ID: 12665801
Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.
PubMed ID: 12665801
DOI: 10.1038/nbt810
PubMed ID: 15850461
Title: The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ.
PubMed ID: 15850461
DOI: 10.1042/bj20050387
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19922875
Title: The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.
PubMed ID: 19922875
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 30361697
Title: Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via beta-catenin.
PubMed ID: 30361697
Sequence Information:
- Length: 286
- Mass: 32949
- Checksum: B5E1B617A38E758B
- Sequence:
MADLEEQLSD EEKVRIAAKF IIHAPPGEFN EVFNDVRLLL NNDNLLREGA AHAFAQYNLD QFTPVKIEGY EDQVLITEHG DLGNGKFLDP KNRICFKFDH LRKEATDPRP CEVENAVESW RTSVETALRA YVKEHYPNGV CTVYGKKIDG QQTIIACIES HQFQAKNFWN GRWRSEWKFT ITPSTTQVVG ILKIQVHYYE DGNVQLVSHK DIQDSLTVSN EVQTAKEFIK IVEAAENEYQ TAISENYQTM SDTTFKALRR QLPVTRTKID WNKILSYKIG KEMQNA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.