Details for: HLA DPB1

Gene ID: 3115

Symbol: HLA DPB1

Ensembl ID: ENSG00000223865

Description: major histocompatibility complex, class II, DP beta 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: thymocyte (CL0000893)
    Fold Change: 17.79
    Marker Score: 18630
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 5.43
    Marker Score: 11391
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 5.4
    Marker Score: 3809
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 4.74
    Marker Score: 2877
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 4.13
    Marker Score: 4064
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 3.94
    Marker Score: 3153
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 3.86
    Marker Score: 2351
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 3.78
    Marker Score: 4321.5
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 3.36
    Marker Score: 6548
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 3.34
    Marker Score: 2985
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 3.22
    Marker Score: 21008
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 3.2
    Marker Score: 8301
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 3.16
    Marker Score: 1903
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 3.15
    Marker Score: 9357
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 3.13
    Marker Score: 4525
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 3.02
    Marker Score: 1069
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 3.01
    Marker Score: 77040
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.98
    Marker Score: 9408
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 2.96
    Marker Score: 3497.5
  • Cell Name: centroblast (CL0009112)
    Fold Change: 2.96
    Marker Score: 1460
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.93
    Marker Score: 2757.5
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 2.92
    Marker Score: 7415
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 2.9
    Marker Score: 1497
  • Cell Name: cord blood hematopoietic stem cell (CL2000095)
    Fold Change: 2.88
    Marker Score: 2171
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 2.87
    Marker Score: 15064
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.83
    Marker Score: 4927
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.81
    Marker Score: 32714
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 2.73
    Marker Score: 635
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.72
    Marker Score: 151911
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.71
    Marker Score: 2049
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 2.68
    Marker Score: 3947
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 2.65
    Marker Score: 6391
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2.61
    Marker Score: 7317
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.59
    Marker Score: 4156
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.58
    Marker Score: 26184
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.57
    Marker Score: 1864
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 2.56
    Marker Score: 1498
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: 2.53
    Marker Score: 15362
  • Cell Name: exhausted T cell (CL0011025)
    Fold Change: 2.51
    Marker Score: 1444
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.4
    Marker Score: 2016
  • Cell Name: immature B cell (CL0000816)
    Fold Change: 2.38
    Marker Score: 1575
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 2.33
    Marker Score: 2005
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 2.31
    Marker Score: 2504
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.31
    Marker Score: 3183
  • Cell Name: centrocyte (CL0009111)
    Fold Change: 2.29
    Marker Score: 544
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 2.26
    Marker Score: 2181
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 2.22
    Marker Score: 721
  • Cell Name: B-1b B cell (CL0000821)
    Fold Change: 2.22
    Marker Score: 510
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 2.19
    Marker Score: 911
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 2.17
    Marker Score: 1058
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 2.16
    Marker Score: 1489
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.1
    Marker Score: 3553
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 2.09
    Marker Score: 5687
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.05
    Marker Score: 1744
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.02
    Marker Score: 8407
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.97
    Marker Score: 8077
  • Cell Name: IgM plasma cell (CL0000986)
    Fold Change: 1.95
    Marker Score: 681
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.9
    Marker Score: 3788
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 1.89
    Marker Score: 736
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.85
    Marker Score: 11860
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.85
    Marker Score: 975
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: 1.85
    Marker Score: 1137
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 1.82
    Marker Score: 553
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 1.82
    Marker Score: 2199
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 1.75
    Marker Score: 398
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 1.75
    Marker Score: 445
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 1.73
    Marker Score: 746
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 1.72
    Marker Score: 504
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 1.7
    Marker Score: 587
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.69
    Marker Score: 1690.5
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.67
    Marker Score: 1697
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 1.65
    Marker Score: 2709
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.64
    Marker Score: 349
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.64
    Marker Score: 814
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 1.62
    Marker Score: 1461
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.6
    Marker Score: 559
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.6
    Marker Score: 400
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.59
    Marker Score: 511
  • Cell Name: B cell (CL0000236)
    Fold Change: 1.58
    Marker Score: 1507
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 1.58
    Marker Score: 3094
  • Cell Name: pre-B-I cell (CL0000956)
    Fold Change: 1.57
    Marker Score: 401
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 1.57
    Marker Score: 1572
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 1.53
    Marker Score: 4470
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.5
    Marker Score: 1022
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 1.5
    Marker Score: 418
  • Cell Name: Langerhans cell (CL0000453)
    Fold Change: 1.5
    Marker Score: 448
  • Cell Name: plasmacytoid dendritic cell, human (CL0001058)
    Fold Change: 1.49
    Marker Score: 391
  • Cell Name: macrophage (CL0000235)
    Fold Change: 1.49
    Marker Score: 1653
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 1.49
    Marker Score: 513
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.47
    Marker Score: 980
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.47
    Marker Score: 1465
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 1.47
    Marker Score: 497
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 1.47
    Marker Score: 1006
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.45
    Marker Score: 3301
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.45
    Marker Score: 3996
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.44
    Marker Score: 283
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 1.44
    Marker Score: 347
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 1.44
    Marker Score: 774
  • Cell Name: mature B cell (CL0000785)
    Fold Change: 1.44
    Marker Score: 1054
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 1.43
    Marker Score: 311

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Other Information

**Key characteristics:** * The DPB1 gene is located on chromosome 15q21.1. * It is a member of the HLA class II family of antigens. * The DPB1 protein is a heterodimeric protein composed of two identical heavy chains and two identical light chains. * The DPB1 protein is expressed on the surface of antigen-presenting cells, such as dendritic cells and macrophages. * The DPB1 protein is responsible for the processing and presentation of exogenous peptide antigens to T cells. **Pathways and functions:** * The DPB1 protein is expressed in high levels in dendritic cells and macrophages, which are the cells that take up and process antigens and present them to T cells. * The DPB1 protein is also expressed in naive B cells, which are the cells that are responsible for the immune response. * The DPB1 protein is involved in the adaptive immune response, as it is expressed on the surface of antigen-presenting cells and is responsible for the processing and presentation of peptide antigens to T cells. * The DPB1 protein is also involved in the regulation of the immune response, as it can interact with the immune checkpoint molecule PD-1 and block its activity. **Clinical significance:** * Mutations in the DPB1 gene have been linked to a number of autoimmune diseases, including systemic sclerosis, lupus, and rheumatoid arthritis. * The DPB1 gene is also a target for immunotherapy, as it can be used to develop drugs that block the activity of the DPB1 protein and inhibit the immune response.

Genular Protein ID: 374868705

Symbol: DPB1_HUMAN

Name: HLA class II histocompatibility antigen, DP beta 1 chain

UniProtKB Accession Codes:

P04440 A0PFJ7 A5I886 A8YPB3 B5U8B4 B7VF80 B7VF87 B8ZX68 B8ZYT0 B9W5S8 B9W6F7 B9W6F9 C0MPP5 C0MPQ2 C0MPQ3 C0MPQ5 C0MPQ6 C0MPQ7 C4R9J5 C5IZL1 O00259 O19698 O19700 O19702 O19749 O46884 O77952 O98215 O98216 O98217 O98218 O98219 O98222 O98223 P01916 P04232 P13763 P79493 P79608 Q0P0L4 Q0ZFN3 Q14279 Q27S71 Q29682 Q29684 Q29698 Q29714 Q29775 Q29776 Q29778 Q29779 Q29781 Q29827 Q29828 Q29879 Q29880 Q29898 Q29977 Q2MGW3 Q30015 Q30031 Q30032 Q30033 Q30034 Q30050 Q30051 Q30052 Q30053 Q30054 Q30055 Q30174 Q4GY31 Q4JHD8 Q5ENE0 Q5ENE1 Q5ENW3 Q5EP46 Q5EP47 Q5EP49 Q5EP51 Q5EP52 Q5EP53 Q5EP56 Q5I4H8 Q5I4H9 Q5ISH4 Q5ISH5 Q5SQ73 Q5STP2 Q5YLA6 Q6IVX1 Q6LBX2 Q6LBX3 Q6LBX4 Q6LBX5 Q6LBX6 Q6LBX7 Q6PWX6 Q6TAS4 Q714U1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 100 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 10 PIR 17 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 6098459

Title: Structure and polymorphism of the HLA class II SB light chain genes.

PubMed ID: 6098459

DOI: 10.1002/j.1460-2075.1984.tb02245.x

PubMed ID: 2998758

Title: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression.

PubMed ID: 2998758

DOI: 10.1002/j.1460-2075.1985.tb04012.x

PubMed ID: 2987832

Title: Complete nucleotide sequence of a functional HLA-DP beta gene and the region between the DP beta 1 and DP alpha 1 genes: comparison of the 5' ends of HLA class II genes.

PubMed ID: 2987832

DOI: 10.1093/nar/13.5.1607

PubMed ID: 3036829

Title: Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes.

PubMed ID: 3036829

DOI: 10.1016/s0021-9258(18)47483-2

PubMed ID: 2838415

Title: The beta-chains of DP4 molecules from different haplotypes are encoded by the same gene.

PubMed ID: 2838415

DOI: 10.1016/0888-7543(88)90103-6

PubMed ID: 1529429

Title: A new HLA-DPB1 allele from a patient with systemic lupus erythematosus.

PubMed ID: 1529429

DOI: 10.1111/j.1399-0039.1992.tb01938.x

PubMed ID: 16189666

Title: Extended HLA-DPB1 polymorphism: an RNA approach for HLA-DPB1 typing.

PubMed ID: 16189666

DOI: 10.1007/s00251-005-0043-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2714855

Title: Sequence polymorphism of HLA-DP beta chains.

PubMed ID: 2714855

DOI: 10.1007/bf00352845

PubMed ID: 7638863

Title: HLA-DPB1 alleles in a population from north India and description of a new variant (DPB1*5601).

PubMed ID: 7638863

DOI: 10.1111/j.1399-0039.1995.tb02450.x

PubMed ID: 1481203

Title: Characterization of novel HLA-DPB1 alleles by oligotyping and nucleotide sequencing.

PubMed ID: 1481203

DOI: 10.1111/j.1399-0039.1992.tb02055.x

PubMed ID: 8896187

Title: DPB1*TF, a novel HLA class II DPB1 allele (DPB1*6701) identified in a Turkish family.

PubMed ID: 8896187

DOI: 10.1111/j.1399-0039.1996.tb02637.x

PubMed ID: 9756410

Title: Identification of two new DPB1 alleles, DPB1*7701 and *7801, by sequence-based typing.

PubMed ID: 9756410

DOI: 10.1111/j.1399-0039.1998.tb02285.x

PubMed ID: 9756411

Title: Identification of a new DPB1 allele (DPB1*7901) by sequence-based typing.

PubMed ID: 9756411

DOI: 10.1111/j.1399-0039.1998.tb02286.x

PubMed ID: 16147881

Title: DNA-sequence determination of exon 2 of a novel HLA-DPB1 allele, HLA-DPB1*0403.

PubMed ID: 16147881

DOI: 10.1080/10425170500061442

PubMed ID: 1440570

Title: Genetic diversity within the HLA class II region: ten new DPB1 alleles and their population distribution.

PubMed ID: 1440570

DOI: 10.1111/j.1399-0039.1992.tb02109.x

PubMed ID: 7806296

Title: Identification of the novel HLA-DPB1*5801 allele detected by sequenced based typing.

PubMed ID: 7806296

DOI: 10.1007/bf00182337

PubMed ID: 8773318

Title: Three new DPB1 alleles identified in a Bantu-speaking population from central Cameroon.

PubMed ID: 8773318

DOI: 10.1111/j.1399-0039.1996.tb02556.x

PubMed ID: 6330724

Title: Molecular organization of the HLA-SB region of the human major histocompatibility complex and evidence for two SB beta-chain genes.

PubMed ID: 6330724

DOI: 10.1073/pnas.81.13.3934

PubMed ID: 19775376

Title: In a study for acne vulgaris, sequence-based HLA typing showed a novel DPB1 allele, DPB1*2402.

PubMed ID: 19775376

DOI: 10.1111/j.1399-0039.2009.01325.x

PubMed ID: 2460556

Title: Analysis of HLA-DP allelic sequence polymorphism using the in vitro enzymatic DNA amplification of DP-alpha and DP-beta loci.

PubMed ID: 2460556

PubMed ID: 2242906

Title: Rapid HLA-DPB typing using enzymatically amplified DNA and nonradioactive sequence-specific oligonucleotide probes.

PubMed ID: 2242906

DOI: 10.1007/bf00187094

PubMed ID: 8344726

Title: Novel class II HLA-DRB4 and DPB1 alleles found in the Belgian population.

PubMed ID: 8344726

DOI: 10.1007/bf00210483

PubMed ID: 7901923

Title: Identification of a new HLA-DPB1 allele detected by PCR-RFLP and its nucleotide sequence determination by direct sequencing after PCR amplification.

PubMed ID: 7901923

DOI: 10.1111/j.1399-0039.1993.tb02016.x

PubMed ID: 7912859

Title: A new HLA-DPB1 allele, DPB1*SUT (DPB1*4701).

PubMed ID: 7912859

DOI: 10.1111/j.1399-0039.1994.tb02297.x

PubMed ID: 7839356

Title: Direct sequencing of a novel DPB1 allele (DPB1*5101) of the heterozygote from the membrane of reverse dot blot analysis.

PubMed ID: 7839356

DOI: 10.1111/j.1399-0039.1994.tb02382.x

PubMed ID: 8781129

Title: DPB1*BR: an Mhc class II DPB1 allele (DPB1*6601) of negroid origin.

PubMed ID: 8781129

DOI: 10.1007/s002510050145

PubMed ID: 8824162

Title: Identification of a new HLA-DPB1*6501 allele in a Caucasian individual.

PubMed ID: 8824162

DOI: 10.1007/bf02602812

PubMed ID: 11169249

Title: Two new HLA DPB1 alleles identified by sequence-based typing: DPB1*8201 and DPB1*8301.

PubMed ID: 11169249

DOI: 10.1034/j.1399-0039.2000.560613.x

PubMed ID: 11556983

Title: DPB1*8601, a previously unrecognized DPB1 variant in the Caucasoid population.

PubMed ID: 11556983

DOI: 10.1034/j.1399-0039.2001.057006536.x

PubMed ID: 11782281

Title: Three new DP alleles identified in a study of 800 unrelated bone marrow donor-recipient pairs.

PubMed ID: 11782281

DOI: 10.1034/j.1399-0039.2001.580410.x

PubMed ID: 12135440

Title: Identification of a new HLA-DPB1 allele,HLA-DPB1*9001.

PubMed ID: 12135440

DOI: 10.1034/j.1399-0039.2002.590419.x

PubMed ID: 12694578

Title: Identification of a novel DPB1 allele, DPB1*9301, by sequence-based typing in a Lahu ethnic minority of China.

PubMed ID: 12694578

DOI: 10.1046/j.0001-2815.2002.00143.x

PubMed ID: 12890000

Title: High resolution sequence-based DPB1 typing identified two novel DPB1 alleles, DPB1*9401 and DPB1*9501, from a Kenyan population.

PubMed ID: 12890000

DOI: 10.1034/j.1399-0039.2003.00066.x

PubMed ID: 12890001

Title: Sequence-based typing identifies a novel HLA-DPB1 allele, DPB1*9601.

PubMed ID: 12890001

DOI: 10.1034/j.1399-0039.2003.00081.x

PubMed ID: 15361132

Title: Identification of a novel HLA-DPB1 allele--DPB1*0102.

PubMed ID: 15361132

DOI: 10.1111/j.1399-0039.2004.00276.x

PubMed ID: 16866899

Title: Identification of a novel HLA-DPB1 allele, DPB1*1702.

PubMed ID: 16866899

DOI: 10.1111/j.1399-0039.2006.00630.x

PubMed ID: 8085260

Title: Seven new DPB1 alleles and their population distribution.

PubMed ID: 8085260

DOI: 10.1111/j.1399-0039.1994.tb02333.x

PubMed ID: 9174146

Title: Six new DPB1 alleles identified in a study of 1,302 unrelated bone marrow donor-recipient pairs.

PubMed ID: 9174146

DOI: 10.1111/j.1399-0039.1997.tb02788.x

PubMed ID: 10090623

Title: Four new DP alleles identified in a study of 500 unrelated bone marrow donor-recipient pairs.

PubMed ID: 10090623

DOI: 10.1034/j.1399-0039.1999.530213.x

PubMed ID: 15140044

Title: Identification of a novel HLA-DPB1 allele, DPB1*9701, by sequence-based typing.

PubMed ID: 15140044

DOI: 10.1111/j.0001-2815.2004.00198.x

PubMed ID: 7744621

Title: Novel HLA-DPB1 alleles detected in the Ethiopian population.

PubMed ID: 7744621

DOI: 10.1016/0198-8859(94)00100-5

PubMed ID: 8851734

Title: DPB1*5901a: a novel HLA-DPB1 allele from a Caucasian family with insulin-dependent diabetes mellitus.

PubMed ID: 8851734

DOI: 10.1111/j.1399-0039.1996.tb02533.x

PubMed ID: 15982263

Title: Identification of a new allele in a Sicilian individual: HLA-DPB1*0302.

PubMed ID: 15982263

DOI: 10.1111/j.1399-0039.2005.00429.x

PubMed ID: 1412421

Title: DPB1*WA4 - an additional HLA class II allele identified in west Africa.

PubMed ID: 1412421

DOI: 10.1111/j.1399-0039.1992.tb01966.x

PubMed ID: 1358867

Title: Family study on HLA-DPB1 polymorphism: linkage analysis with HLA-DR/DQ and two 'new' alleles.

PubMed ID: 1358867

DOI: 10.1016/0198-8859(92)90113-2

PubMed ID: 7817379

Title: A novel HLA-DPB1 allele, DPB1*3601 (DPB1*KT).

PubMed ID: 7817379

DOI: 10.1111/j.1399-0039.1994.tb02370.x

PubMed ID: 9694359

Title: Three new DP alleles identified in sub-Saharan Africa: DPB1*7401, DPA1*02013, and DPA1*0302.

PubMed ID: 9694359

DOI: 10.1111/j.1399-0039.1998.tb03009.x

PubMed ID: 8525482

Title: Characterization of a new DPB1 allele (DPB1*5701) isolated from a Caucasian individual.

PubMed ID: 8525482

DOI: 10.1111/j.1399-0039.1995.tb03122.x

PubMed ID: 10958363

Title: The nucleotide sequence of two new DP alleles, DPA1*02015 and DPB1*8401, identified in a Chinese subject.

PubMed ID: 10958363

DOI: 10.1034/j.1399-0039.2000.560114.x

PubMed ID: 6310612

Title: Genetic mapping of a human class II antigen beta-chain cDNA clone to the SB region of the HLA complex.

PubMed ID: 6310612

DOI: 10.1073/pnas.80.19.6036

PubMed ID: 8598037

Title: Invariant chain structure and MHC class II function.

PubMed ID: 8598037

DOI: 10.1016/s0092-8674(00)81025-9

PubMed ID: 11684289

Title: Presentation of antigens by MHC class II molecules: getting the most out of them.

PubMed ID: 11684289

DOI: 10.1016/s0161-5890(01)00069-4

PubMed ID: 18046453

Title: MHC class II molecules on the move for successful antigen presentation.

PubMed ID: 18046453

DOI: 10.1038/sj.emboj.7601945

PubMed ID: 17241953

Title: Autophagy in MHC class II presentation: sampling from within.

PubMed ID: 17241953

DOI: 10.1016/j.immuni.2007.01.005

PubMed ID: 19092054

Title: MHC class II transport at a glance.

PubMed ID: 19092054

DOI: 10.1242/jcs.035089

PubMed ID: 19533806

Title: CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract.

PubMed ID: 19533806

DOI: 10.3748/wjg.15.2855

Sequence Information:

  • Length: 258
  • Mass: 29159
  • Checksum: E74777D438DE9C41
  • Sequence:
    • MMVLQVSAAP RTVALTALLM VLLTSVVQGR ATPENYLFQG RQECYAFNGT QRFLERYIYN 
REEFARFDSD VGEFRAVTEL GRPAAEYWNS QKDILEEKRA VPDRMCRHNY ELGGPMTLQR 
RVQPRVNVSP SKKGPLQHHN LLVCHVTDFY PGSIQVRWFL NGQEETAGVV STNLIRNGDW 
TFQILVMLEM TPQQGDVYTC QVEHTSLDSP VTVEWKAQSD SARSKTLTGA GGFVLGLIIC 
GVGIFMHRRS KKVQRGSA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.