Details for: HSPA6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 151.8529
Cell Significance Index: -23.6200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 94.0691
Cell Significance Index: -23.8600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 49.2432
Cell Significance Index: -25.3300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 19.4573
Cell Significance Index: -23.9900 - Cell Name: theca cell (CL0000503)
Fold Change: 11.5472
Cell Significance Index: 67.8400 - Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: 11.4756
Cell Significance Index: 43.9400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.2315
Cell Significance Index: -24.7300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 7.9363
Cell Significance Index: 227.5000 - Cell Name: glomerular capillary endothelial cell (CL1001005)
Fold Change: 7.4511
Cell Significance Index: 27.7700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.1124
Cell Significance Index: -24.1200 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 4.8081
Cell Significance Index: 37.0600 - Cell Name: kidney cell (CL1000497)
Fold Change: 3.3510
Cell Significance Index: 26.7600 - Cell Name: vasa recta ascending limb cell (CL1001131)
Fold Change: 1.2780
Cell Significance Index: 8.3300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.1475
Cell Significance Index: 60.2500 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.0556
Cell Significance Index: 8.7300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.7805
Cell Significance Index: 148.5300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.6999
Cell Significance Index: 18.4100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 0.6899
Cell Significance Index: -1.5100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.5696
Cell Significance Index: 19.8000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5607
Cell Significance Index: 55.4700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5351
Cell Significance Index: 483.1200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.5122
Cell Significance Index: 60.4000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2912
Cell Significance Index: 57.7900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2456
Cell Significance Index: 12.7600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2041
Cell Significance Index: 33.2000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.1968
Cell Significance Index: 2.5200 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.1863
Cell Significance Index: 0.4200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1157
Cell Significance Index: 7.7800 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0877
Cell Significance Index: 11.2400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0739
Cell Significance Index: 8.0400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.0706
Cell Significance Index: 1.3100 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0640
Cell Significance Index: 0.9900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0564
Cell Significance Index: 0.7700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0341
Cell Significance Index: 21.2800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0247
Cell Significance Index: 2.8800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0235
Cell Significance Index: 10.4100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0207
Cell Significance Index: 15.6800 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0174
Cell Significance Index: 1.7800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0170
Cell Significance Index: 2.3400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0012
Cell Significance Index: 0.0400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0046
Cell Significance Index: -0.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0076
Cell Significance Index: -0.3500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0133
Cell Significance Index: -9.8200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0137
Cell Significance Index: -7.7500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0313
Cell Significance Index: -9.0000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0344
Cell Significance Index: -25.2300 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0352
Cell Significance Index: -0.8800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0375
Cell Significance Index: -6.4100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0411
Cell Significance Index: -22.4400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0417
Cell Significance Index: -8.7800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0479
Cell Significance Index: -17.1900 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0692
Cell Significance Index: -3.5000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0797
Cell Significance Index: -5.5100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0805
Cell Significance Index: -14.5100 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: -0.0933
Cell Significance Index: -0.2500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0939
Cell Significance Index: -4.4200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0997
Cell Significance Index: -4.6500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1002
Cell Significance Index: -11.4800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1069
Cell Significance Index: -21.4400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1152
Cell Significance Index: -3.2200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1163
Cell Significance Index: -2.5200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1191
Cell Significance Index: -14.6400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1356
Cell Significance Index: -5.5600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1362
Cell Significance Index: -3.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1515
Cell Significance Index: -22.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1654
Cell Significance Index: -21.3700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1845
Cell Significance Index: -21.0600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2083
Cell Significance Index: -14.7300 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.2390
Cell Significance Index: -3.3500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2573
Cell Significance Index: -19.1800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2608
Cell Significance Index: -15.9900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2711
Cell Significance Index: -3.0800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3066
Cell Significance Index: -18.4100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3199
Cell Significance Index: -24.5500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3199
Cell Significance Index: -5.4800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3315
Cell Significance Index: -20.9000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3692
Cell Significance Index: -23.8200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3744
Cell Significance Index: -10.1900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3825
Cell Significance Index: -14.0400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3949
Cell Significance Index: -24.2700 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.4011
Cell Significance Index: -5.7100 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.4157
Cell Significance Index: -5.8400 - Cell Name: urothelial cell (CL0000731)
Fold Change: -0.4402
Cell Significance Index: -3.0700 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: -0.4472
Cell Significance Index: -4.8100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.4551
Cell Significance Index: -25.5400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4673
Cell Significance Index: -12.5000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4743
Cell Significance Index: -15.1900 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.4897
Cell Significance Index: -7.1100 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.4984
Cell Significance Index: -2.6100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.5433
Cell Significance Index: -24.0300 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.5446
Cell Significance Index: -3.6900 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.5582
Cell Significance Index: -2.4300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.5810
Cell Significance Index: -3.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.5981
Cell Significance Index: -15.9700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.6101
Cell Significance Index: -12.7700 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.6121
Cell Significance Index: -19.3600 - Cell Name: mature T cell (CL0002419)
Fold Change: -0.6170
Cell Significance Index: -4.4400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.6234
Cell Significance Index: -21.8400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6362
Cell Significance Index: -24.0900 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.6434
Cell Significance Index: -11.3700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3366780090
Symbol: HSP76_HUMAN
Name: Heat shock 70 kDa protein 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2327978
Title: The human heat-shock protein family. Expression of a novel heat-inducible HSP70 (HSP70B') and isolation of its cDNA and genomic DNA.
PubMed ID: 2327978
DOI: 10.1042/bj2670125
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1346391
Title: The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1.
PubMed ID: 1346391
PubMed ID: 3184191
Title: Cis-acting elements involved in the regulated expression of a human HSP70 gene.
PubMed ID: 3184191
PubMed ID: 23921388
Title: Identification and characterization of a novel human methyltransferase modulating Hsp70 function through lysine methylation.
PubMed ID: 23921388
PubMed ID: 26865365
Title: The human HSP70 family of chaperones: where do we stand?
PubMed ID: 26865365
PubMed ID: 20072699
Title: Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78.
PubMed ID: 20072699
Sequence Information:
- Length: 643
- Mass: 71028
- Checksum: BCE348F0226DB70B
- Sequence:
MQAPRELAVG IDLGTTYSCV GVFQQGRVEI LANDQGNRTT PSYVAFTDTE RLVGDAAKSQ AALNPHNTVF DAKRLIGRKF ADTTVQSDMK HWPFRVVSEG GKPKVRVCYR GEDKTFYPEE ISSMVLSKMK ETAEAYLGQP VKHAVITVPA YFNDSQRQAT KDAGAIAGLN VLRIINEPTA AAIAYGLDRR GAGERNVLIF DLGGGTFDVS VLSIDAGVFE VKATAGDTHL GGEDFDNRLV NHFMEEFRRK HGKDLSGNKR ALRRLRTACE RAKRTLSSST QATLEIDSLF EGVDFYTSIT RARFEELCSD LFRSTLEPVE KALRDAKLDK AQIHDVVLVG GSTRIPKVQK LLQDFFNGKE LNKSINPDEA VAYGAAVQAA VLMGDKCEKV QDLLLLDVAP LSLGLETAGG VMTTLIQRNA TIPTKQTQTF TTYSDNQPGV FIQVYEGERA MTKDNNLLGR FELSGIPPAP RGVPQIEVTF DIDANGILSV TATDRSTGKA NKITITNDKG RLSKEEVERM VHEAEQYKAE DEAQRDRVAA KNSLEAHVFH VKGSLQEESL RDKIPEEDRR KMQDKCREVL AWLEHNQLAE KEEYEHQKRE LEQICRPIFS RLYGGPGVPG GSSCGTQARQ GDPSTGPIIE EVD
Genular Protein ID: 3866297538
Symbol: B3KSM6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 643
- Mass: 70972
- Checksum: E5121DEC9E04132D
- Sequence:
MQAPRELAVG IDLGTTYSCA GVFQQGRVEI LANDQGNRTT PSYVAFTDTE RLVGDAAKSQ AALNPHNTVF DAKRLIGRKF ADTTVQSDMK HWPFRVVSEG GKPKVRVCYR GEDKTFYPEE ISSMVLSKMK ETAEAYLGQP VKHAVITVPA YFNDSQRQAT KDAGAIAGLN VLRIINEPTA AAIAYGLDRR GAGERNVLIF DLGGGTFDVS VLSIDAGVFE VKATAGDTHL GGEDFDNRLV NHFMEEFRRK HGKDLSGNKR ALRRLRTACE RAKRTLSSST QATLEIDSLF EGVDFYTSIT RARFEELCSD LFRSTLEPVE KALRDAKLDK AQIHDVVLVG GSTRIPKVQK LLQDFFNGKE LNKSINPDEA VAYGAAAQAA VLMGDKCEKV QDLLLLDVAP LSLGLETAGG VMTTLIQRNA TIPTKQTQTF TTYSDNQPGV FIQVYEGERA MTKDNNLLGR FELSGIPPAP RGVPQIEVTF DIDANGILSV TATDRSTGKA NKITITNDKG RLSKEEVERM VHEAEQYKAE DEAQRDRVAA KNSLEAHVFH VKGSLQEESL RDKIPEEDRR KMQDKCREVL AWLEHNQLAE KEEYEHQKRE LEQICRPIFS RLYGGPGVPG GSSCGTQARQ GDPSTGPIIE EVD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.