Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: granular cell of epidermis (CL0002189)
Fold Change: 11.7966
Cell Significance Index: 13.5800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 3.3124
Cell Significance Index: 82.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.9191
Cell Significance Index: 93.5000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 2.8956
Cell Significance Index: 177.5300 - Cell Name: epidermal cell (CL0000362)
Fold Change: 2.5708
Cell Significance Index: 5.8000 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 1.3285
Cell Significance Index: 32.1800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.8127
Cell Significance Index: 154.6600 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 0.7493
Cell Significance Index: 11.3800 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 0.7061
Cell Significance Index: 2.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5815
Cell Significance Index: 57.5200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5088
Cell Significance Index: 10.8400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4665
Cell Significance Index: 421.1800 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.3723
Cell Significance Index: 5.3000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3383
Cell Significance Index: 36.8000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.3249
Cell Significance Index: 143.6600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3192
Cell Significance Index: 51.9200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2455
Cell Significance Index: 14.7400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1781
Cell Significance Index: 12.3200 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.1716
Cell Significance Index: 1.3700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1586
Cell Significance Index: 12.1700 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.1536
Cell Significance Index: 1.9100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1224
Cell Significance Index: 1.6700 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.0933
Cell Significance Index: 1.0900 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.0892
Cell Significance Index: 1.5000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0732
Cell Significance Index: 1.0800 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.0588
Cell Significance Index: 0.5900 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.0443
Cell Significance Index: 0.5600 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.0402
Cell Significance Index: 1.2700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0322
Cell Significance Index: 1.2200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0285
Cell Significance Index: 1.2600 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.0253
Cell Significance Index: 0.2500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0232
Cell Significance Index: 4.6500 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.0180
Cell Significance Index: 0.4500 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.0174
Cell Significance Index: 0.2200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0166
Cell Significance Index: 0.3600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0149
Cell Significance Index: 0.4000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0148
Cell Significance Index: 1.0500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0139
Cell Significance Index: 2.0200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0135
Cell Significance Index: 0.6100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0099
Cell Significance Index: 18.3300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0098
Cell Significance Index: 1.9400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0065
Cell Significance Index: 8.7900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0057
Cell Significance Index: 2.0600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0044
Cell Significance Index: 6.7600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0032
Cell Significance Index: 5.9900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0004
Cell Significance Index: 0.2300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0020
Cell Significance Index: -0.0700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0024
Cell Significance Index: -1.7800 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.0025
Cell Significance Index: -0.0300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0025
Cell Significance Index: -1.8700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0025
Cell Significance Index: -1.9300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0031
Cell Significance Index: -0.9000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0032
Cell Significance Index: -2.0000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0033
Cell Significance Index: -1.5000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0033
Cell Significance Index: -1.7800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0034
Cell Significance Index: -1.8900 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0040
Cell Significance Index: -0.1000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0042
Cell Significance Index: -0.0900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0058
Cell Significance Index: -0.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0060
Cell Significance Index: -1.0800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0060
Cell Significance Index: -0.0900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0077
Cell Significance Index: -0.1600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0088
Cell Significance Index: -1.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0090
Cell Significance Index: -1.9000 - Cell Name: acinar cell (CL0000622)
Fold Change: -0.0092
Cell Significance Index: -0.1200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0109
Cell Significance Index: -0.2900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0110
Cell Significance Index: -1.2800 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0120
Cell Significance Index: -0.1900 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: -0.0126
Cell Significance Index: -0.1400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0130
Cell Significance Index: -1.6000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0137
Cell Significance Index: -0.7100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0141
Cell Significance Index: -1.9300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0151
Cell Significance Index: -1.7400 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.0156
Cell Significance Index: -0.2100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0174
Cell Significance Index: -2.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0182
Cell Significance Index: -1.9000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0188
Cell Significance Index: -1.9200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0203
Cell Significance Index: -0.2900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0220
Cell Significance Index: -0.3700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0228
Cell Significance Index: -0.5000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0231
Cell Significance Index: -1.5500 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.0248
Cell Significance Index: -0.3200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0256
Cell Significance Index: -0.7100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0288
Cell Significance Index: -1.7700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0291
Cell Significance Index: -1.0700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0291
Cell Significance Index: -1.1900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0312
Cell Significance Index: -1.7500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0315
Cell Significance Index: -2.3500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0335
Cell Significance Index: -2.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0344
Cell Significance Index: -1.7900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0347
Cell Significance Index: -1.2100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0365
Cell Significance Index: -1.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0408
Cell Significance Index: -2.1400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0428
Cell Significance Index: -2.0100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0436
Cell Significance Index: -1.3900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0442
Cell Significance Index: -1.1400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0452
Cell Significance Index: -0.5800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0485
Cell Significance Index: -1.7000 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: -0.0488
Cell Significance Index: -0.5500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1749292223
Symbol: DSC1_HUMAN
Name: Desmocollin-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8507556
Title: Differential synthesis of type 1 and type 2 desmocollin mRNAs in human stratified epithelia.
PubMed ID: 8507556
PubMed ID: 8288219
Title: Cloning of the cDNA (DSC1) coding for human type 1 desmocollin and its assignment to chromosome 18.
PubMed ID: 8288219
PubMed ID: 11027496
Title: Genomic organization and amplification of the human desmosomal cadherin genes DSC1 and DSC3, encoding desmocollin types 1 and 3.
PubMed ID: 11027496
PubMed ID: 1713860
Title: Keratinization is associated with the expression of a new protein related to the desmosomal cadherins DGII/III.
PubMed ID: 1713860
PubMed ID: 17487921
Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.
PubMed ID: 17487921
PubMed ID: 19759396
Title: Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
PubMed ID: 19759396
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
Sequence Information:
- Length: 894
- Mass: 99987
- Checksum: 2E0C835F6FE2E77F
- Sequence:
MALASAAPGS IFCKQLLFSL LVLTLLCDAC QKVYLRVPSH LQAETLVGKV NLEECLKSAS LIRSSDPAFR ILEDGSIYTT HDLILSSERK SFSIFLSDGQ RREQQEIKVV LSARENKSPK KRHTKDTALK RSKRRWAPIP ASLMENSLGP FPQHVQQIQS DAAQNYTIFY SISGPGVDKE PFNLFYIEKD TGDIFCTRSI DREKYEQFAL YGYATTADGY APEYPLPLII KIEDDNDNAP YFEHRVTIFT VPENCRSGTS VGKVTATDLD EPDTLHTRLK YKILQQIPDH PKHFSIHPDT GVITTTTPFL DREKCDTYQL IMEVRDMGGQ PFGLFNTGTI TISLEDENDN PPSFTETSYV TEVEENRIDV EILRMKVQDQ DLPNTPHSKA VYKILQGNEN GNFIISTDPN TNEGVLCVVK PLNYEVNRQV ILQVGVINEA QFSKAASSQT PTMCTTTVTV KIIDSDEGPE CHPPVKVIQS QDGFPAGQEL LGYKALDPEI SSGEGLRYQK LGDEDNWFEI NQHTGDLRTL KVLDRESKFV KNNQYNISVV AVDAVGRSCT GTLVVHLDDY NDHAPQIDKE VTICQNNEDF AVLKPVDPDG PENGPPFQFF LDNSASKNWN IEEKDGKTAI LRQRQNLDYN YYSVPIQIKD RHGLVATHML TVRVCDCSTP SECRMKDKST RDVRPNVILG RWAILAMVLG SVLLLCILFT CFCVTAKRTV KKCFPEDIAQ QNLIVSNTEG PGEEVTEANI RLPMQTSNIC DTSMSVGTVG GQGIKTQQSF EMVKGGYTLD SNKGGGHQTL ESVKGVGQGD TGRYAYTDWQ SFTQPRLGEK VYLCGQDEEH KHCEDYVCSY NYEGKGSLAG SVGCCSDRQE EEGLEFLDHL EPKFRTLAKT CIKK
Genular Protein ID: 3456259431
Symbol: Q9HB00_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11027496
Title: Genomic organization and amplification of the human desmosomal cadherin genes DSC1 and DSC3, encoding desmocollin types 1 and 3.
PubMed ID: 11027496
PubMed ID: 11181995
Sequence Information:
- Length: 840
- Mass: 93835
- Checksum: DF66432C933CC9D1
- Sequence:
MALASAAPGS IFCKQLLFSL LVLTLLCDAC QKVYLRVPSH LQAETLVGKV NLEECLKSAS LIRSSDPAFR ILEDGSIYTT HDLILSSERK SFSIFLSDGQ RREQQEIKVV LSARENKSPK KRHTKDTALK RSKRRWAPIP ASLMENSLGP FPQHVQQIQS DAAQNYTIFY SISGPGVDKE PFNLFYIEKD TGDIFCTRSI DREKYEQFAL YGYATTADGY APEYPLPLII KIEDDNDNAP YFEHRVTIFT VPENCRSGTS VGKVTATDLD EPDTLHTRLK YKILQQIPDH PKHFSIHPDT GVITTTTPFL DREKCDTYQL IMEVRDMGGQ PFGLFNTGTI TISLEDENDN PPSFTETSYV TEVEENRIDV EILRMKVQDQ DLPNTPHSKA VYKILQGNEN GNFIISTDPN TNEGVLCVVK PLNYEVNRQV ILQVGVINEA QFSKAASSQT PTMCTTTVTV KIIDSDEGPE CHPPVKVIQS QDGFPAGQEL LGYKALDPEI SSGEGLRYQK LGDEDNWFEI NQHTGDLRTL KVLDRESKFV KNNQYNISVV AVDAVGRSCT GTLVVHLDDY NDHAPQIDKE VTICQNNEDF AVLKPVDPDG PENGPPFQFF LDNSASKNWN IEEKDGKTAI LRQRQNLDYN YYSVPIQIKD RHGLVATHML TVRVCDCSTP SECRMKDKST RDVRPNVILG RWAILAMVLG SVLLLCILFT CFCVTAKRTV KKCFPEDIAQ QNLIVSNTEG PGEEVTEANI RLPMQTSNIC DTSMSVGTVG GQGIKTQQSF EMVKGGYTLD SNKGGGHQTL ESVKGVGQGD TGRYAYTDWQ SFTQPRLGEE SIRGHTLIKN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.