Details for: ZEB1

Gene ID: 6935

Symbol: ZEB1

Ensembl ID: ENSG00000148516

Description: zinc finger E-box binding homeobox 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 521.6971
    Cell Significance Index: -81.1500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 309.0560
    Cell Significance Index: -78.3900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 165.8891
    Cell Significance Index: -78.3200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 147.1851
    Cell Significance Index: -59.8000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 66.4582
    Cell Significance Index: -81.9400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 63.1269
    Cell Significance Index: -60.2700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 27.5229
    Cell Significance Index: -73.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 25.2811
    Cell Significance Index: -55.3300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 20.8259
    Cell Significance Index: -82.1800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 19.6129
    Cell Significance Index: -60.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 8.5479
    Cell Significance Index: 166.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 6.3163
    Cell Significance Index: 354.4400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 6.1067
    Cell Significance Index: 87.8300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 5.7449
    Cell Significance Index: 147.6700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 4.5199
    Cell Significance Index: 30.6300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.3965
    Cell Significance Index: 176.9200
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 3.2778
    Cell Significance Index: 33.9500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.9735
    Cell Significance Index: 63.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.6002
    Cell Significance Index: 199.5400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.3343
    Cell Significance Index: 103.2500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.2669
    Cell Significance Index: 85.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.2243
    Cell Significance Index: 797.8200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1495
    Cell Significance Index: 431.1900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.8319
    Cell Significance Index: 1267.0200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5731
    Cell Significance Index: 312.1800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.5383
    Cell Significance Index: 698.1900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.4987
    Cell Significance Index: 92.1200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.3714
    Cell Significance Index: 32.8900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.2237
    Cell Significance Index: 82.2800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.0942
    Cell Significance Index: 55.3000
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.9980
    Cell Significance Index: 6.0300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.8092
    Cell Significance Index: 11.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.5297
    Cell Significance Index: 100.8100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5046
    Cell Significance Index: 69.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4716
    Cell Significance Index: 888.0100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.3997
    Cell Significance Index: 6.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3986
    Cell Significance Index: 359.9500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3530
    Cell Significance Index: 224.1900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.2904
    Cell Significance Index: 9.3000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.2873
    Cell Significance Index: 7.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2775
    Cell Significance Index: 427.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2157
    Cell Significance Index: 397.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1216
    Cell Significance Index: 165.3000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0587
    Cell Significance Index: 5.8100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0260
    Cell Significance Index: -0.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0411
    Cell Significance Index: -30.4400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0511
    Cell Significance Index: -3.1400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0582
    Cell Significance Index: -0.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0591
    Cell Significance Index: -33.3100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0607
    Cell Significance Index: -37.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0907
    Cell Significance Index: -66.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0921
    Cell Significance Index: -11.3300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0982
    Cell Significance Index: -17.7000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.1058
    Cell Significance Index: -17.2200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1176
    Cell Significance Index: -89.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1387
    Cell Significance Index: -75.7400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1415
    Cell Significance Index: -62.5500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1755
    Cell Significance Index: -25.5100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1779
    Cell Significance Index: -6.2500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2393
    Cell Significance Index: -68.8400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2480
    Cell Significance Index: -29.2500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2622
    Cell Significance Index: -55.2200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3041
    Cell Significance Index: -4.4900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3045
    Cell Significance Index: -52.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3558
    Cell Significance Index: -45.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.3969
    Cell Significance Index: -43.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.4109
    Cell Significance Index: -11.8400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.4280
    Cell Significance Index: -19.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4336
    Cell Significance Index: -45.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4749
    Cell Significance Index: -11.8700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4944
    Cell Significance Index: -31.1600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5261
    Cell Significance Index: -15.0800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5512
    Cell Significance Index: -71.2100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6067
    Cell Significance Index: -61.9700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6682
    Cell Significance Index: -76.2700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6690
    Cell Significance Index: -77.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.7752
    Cell Significance Index: -40.7000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7792
    Cell Significance Index: -89.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.8354
    Cell Significance Index: -57.7800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.8476
    Cell Significance Index: -12.5100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.8490
    Cell Significance Index: -67.2400
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.8678
    Cell Significance Index: -9.0400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.9093
    Cell Significance Index: -64.3100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.9225
    Cell Significance Index: -18.5200
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.9568
    Cell Significance Index: -13.3800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.9686
    Cell Significance Index: -72.1900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9876
    Cell Significance Index: -20.9600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.1074
    Cell Significance Index: -71.4500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.1195
    Cell Significance Index: -67.2100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.1281
    Cell Significance Index: -53.0200
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -1.1513
    Cell Significance Index: -8.3700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.1949
    Cell Significance Index: -14.9000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2202
    Cell Significance Index: -39.9500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.2641
    Cell Significance Index: -26.4600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.2754
    Cell Significance Index: -40.6200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.3223
    Cell Significance Index: -22.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.3693
    Cell Significance Index: -71.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3833
    Cell Significance Index: -48.0700
  • Cell Name: glioblast (CL0000030)
    Fold Change: -1.5081
    Cell Significance Index: -9.4700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.5280
    Cell Significance Index: -26.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ZEB1 is a homeobox gene that belongs to the E-box family of transcription factors. It is characterized by its ability to bind to specific DNA sequences, known as E-boxes, which are involved in the regulation of gene expression. ZEB1 is a negative regulator of several signaling pathways, including those involved in cell proliferation, differentiation, and survival. It is also involved in the regulation of gene expression through the binding of specific transcription factors, such as NF-κB and AP-1. **Pathways and Functions** ZEB1 is involved in several signaling pathways, including: 1. **Cell differentiation**: ZEB1 is involved in the regulation of cell differentiation in various cell types, including neurons, photoreceptor cells, and immune cells. 2. **Immune system function**: ZEB1 is involved in the regulation of immune system function, including the regulation of T-cell differentiation and the response to transforming growth factor beta (TGF-β) signaling. 3. **Cell proliferation**: ZEB1 is involved in the regulation of cell proliferation in various cell types, including keratinocytes and smooth muscle cells. 4. **Chromatin regulation**: ZEB1 is involved in the regulation of chromatin structure and function, including the regulation of gene expression through the binding of specific transcription factors. 5. **Cytokine signaling**: ZEB1 is involved in the regulation of cytokine signaling, including the regulation of interleukin-4 (IL-4) and interleukin-13 (IL-13) signaling. ZEB1 functions as a transcription factor that regulates gene expression by binding to specific DNA sequences, known as E-boxes. It also interacts with other transcription factors, such as NF-κB and AP-1, to regulate gene expression. **Clinical Significance** ZEB1 has been implicated in several diseases, including: 1. **Cancer**: ZEB1 has been shown to be overexpressed in several types of cancer, including breast cancer, lung cancer, and colon cancer. It is involved in the regulation of cell proliferation, differentiation, and survival, and is thought to play a role in the development and progression of cancer. 2. **Neurological disorders**: ZEB1 has been implicated in several neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. It is involved in the regulation of gene expression in neurons and is thought to play a role in the development and progression of these diseases. 3. **Immunological disorders**: ZEB1 has been implicated in several immunological disorders, including rheumatoid arthritis and lupus. It is involved in the regulation of immune system function and is thought to play a role in the development and progression of these diseases. Overall, ZEB1 is a critical transcription factor that regulates gene expression in various cell types and is involved in several signaling pathways. Its dysregulation has been implicated in several diseases, highlighting the importance of further study of this gene.

Genular Protein ID: 3793996728

Symbol: ZEB1_HUMAN

Name: Negative regulator of IL2

UniProtKB Accession Codes:

P37275 B4DJV0 B4DUW9 E9PCM7 F5H4I8 Q12924 Q13800 Q2KJ05 Q5T968 Q5VZ84 Q8NB68

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CORUM 1 CPTC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 12 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 1 RefSeq 6 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8138542

Title: Transcription factors positively and negatively regulating the Na,K-ATPase alpha 1 subunit gene.

PubMed ID: 8138542

DOI: 10.1093/oxfordjournals.jbchem.a124267

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1840704

Title: Identification of a zinc finger protein that inhibits IL-2 gene expression.

PubMed ID: 1840704

DOI: 10.1126/science.1840704

PubMed ID: 16252232

Title: Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells.

PubMed ID: 16252232

DOI: 10.1086/497348

PubMed ID: 16061479

Title: Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.

PubMed ID: 16061479

DOI: 10.1074/jbc.m504477200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19935649

Title: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

PubMed ID: 19935649

DOI: 10.1038/ncb1998

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20175752

Title: ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus.

PubMed ID: 20175752

DOI: 10.1042/bj20091578

PubMed ID: 20418909

Title: ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.

PubMed ID: 20418909

DOI: 10.1038/onc.2010.102

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29119051

Title: USP51 promotes deubiquitination and stabilization of ZEB1.

PubMed ID: 29119051

PubMed ID: 20036349

Title: Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p.

PubMed ID: 20036349

DOI: 10.1016/j.ajhg.2009.12.001

PubMed ID: 23599324

Title: Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.

PubMed ID: 23599324

DOI: 10.1167/iovs.13-11781

PubMed ID: 25190660

Title: Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.

PubMed ID: 25190660

DOI: 10.1167/iovs.14-15247

Sequence Information:

  • Length: 1124
  • Mass: 124074
  • Checksum: 0A2714CC37C848D1
  • Sequence:
    • MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD 
LPTDQTVLPG RSSEREGNAK NCWEDDRKEG QEILGPEAQA DEAGCTVKDD ECESDAENEQ 
NHDPNVEEFL QQQDTAVIFP EAPEEDQRQG TPEASGHDEN GTPDAFSQLL TCPYCDRGYK 
RFTSLKEHIK YRHEKNEDNF SCSLCSYTFA YRTQLERHMT SHKSGRDQRH VTQSGCNRKF 
KCTECGKAFK YKHHLKEHLR IHSGEKPYEC PNCKKRFSHS GSYSSHISSK KCISLIPVNG 
RPRTGLKTSQ CSSPSLSASP GSPTRPQIRQ KIENKPLQEQ LSVNQIKTEP VDYEFKPIVV 
ASGINCSTPL QNGVFTGGGP LQATSSPQGM VQAVVLPTVG LVSPISINLS DIQNVLKVAV 
DGNVIRQVLE NNQANLASKE QETINASPIQ QGGHSVISAI SLPLVDQDGT TKIIINYSLE 
QPSQLQVVPQ NLKKENPVAT NSCKSEKLPE DLTVKSEKDK SFEGGVNDST CLLCDDCPGD 
INALPELKHY DLKQPTQPPP LPAAEAEKPE SSVSSATGDG NLSPSQPPLK NLLSLLKAYY 
ALNAQPSAEE LSKIADSVNL PLDVVKKWFE KMQAGQISVQ SSEPSSPEPG KVNIPAKNND 
QPQSANANEP QDSTVNLQSP LKMTNSPVLP VGSTTNGSRS STPSPSPLNL SSSRNTQGYL 
YTAEGAQEEP QVEPLDLSLP KQQGELLERS TITSVYQNSV YSVQEEPLNL SCAKKEPQKD 
SCVTDSEPVV NVIPPSANPI NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ 
VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE 
NGMYACDLCD KIFQKSSSLL RHKYEHTGKR PHECGICKKA FKHKHHLIEH MRLHSGEKPY 
QCDKCGKRFS HSGSYSQHMN HRYSYCKREA EERDSTEQEE AGPEILSNEH VGARASPSQG 
DSDERESLTR EEDEDSEKEE EEEDKEMEEL QEEKECEKPQ GDEEEEEEEE EVEEEEVEEA 
ENEGEEAKTE GLMKDDRAES QASSLGQKVG ESSEQVSEEK TNEA

Genular Protein ID: 2696943909

Symbol: B4DGU2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DGU2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 906
  • Mass: 99336
  • Checksum: C0D6C7726A054262
  • Sequence:
    • MTSHKSGRDQ RHVTQSGCNR KFKCTECGKA FKYKHHLKEH LRIHSGEKPY ECPNCKKRFS 
HSGSYSSHIS SKKCISLIPV NGRPRTGLKT SQCSSPSLSA SPGSPTRPQI RQKIENKPLQ 
EQLSVNQIKT EPVDYEFKPI VVASGINCST PLQNGVFTGG GPLQATSSPQ GMVQAVVLPT 
VGLVSPISIN LSDIQNVLKV AVDGNVIRQV LENNQANLAS KEQEIINASP IQQGGHSVIS 
AISLPLVDQD GTTKIIINYS LEQPSQLQVV PQNLKKENPV ATNSCKSEKL PEDLTVKSEK 
DKSFEGGVND STCLLCDDCP GDINALPELK HYDLKQPTQP PPLPAAEAEK PESSVSSATG 
DGNLSPSQPP LKNLLSLLKA YYALNAQPSA EELSKIADSV NLPLDVVKKW FEKMQAGQIS 
VQSSEPSSPE PGKVNIPAKN NDQPQSANAN EPQDSTVNLQ SPLKMTNSPV LPVGSTTNGS 
RSSTPSPSPL NLSSSRNTQG YLYTAEGAQE EPQVEPLDLS LPKQQGELLE RSTITSVYQN 
SVYSVQEEPL NLSCAKKEPQ KDSCVTDSEP VVNVIPPSAN PINIAIPTVT AQLPTIVAIA 
DQNSVPCLRA LAANKQTILI PQVAYTYSTT VSPAVQEPPL KVIQPNGNQD ERQDTSSEGV 
SNVEDQNDSD STPPKKKMRK TENGMYACDL CDKIFQKSSS LLRHKYEHTG KRPHECGICK 
KAFKHKHHLI EHMRLHSGEK PYQCDKCGKR FSHSGSYSQH MNHRYSYCKR EAEERDSTEQ 
EEAGPEILSN EHVGARASPS QGDSDERESL TREEDEDSEK EEEEEDKEME ELQEEKECEK 
PQGDEEEEEE EEEVEEEEVE EAENEGEEAK TEGLMKDDRA ESQASSLGQK VGESSEQVSE 
EKTNEA

Genular Protein ID: 578465824

Symbol: B2RBI8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2RBI8

Database IDs:

ARBA 10 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 4 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 1124
  • Mass: 124060
  • Checksum: 109715DD36D859D0
  • Sequence:
    • MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD 
LPTDQTVLPG RSSEREGNAK NCWEDDRKEG QEILGPEAQA DEAGCTVKDD ECESDAENEQ 
NHDPNVEEFL QQQDTAVIFP EAPEEDQRQG TPEASGHDEN GTPDAFSQLL TCPYCDRGYK 
RFTSLKEHIK YRHEKNEDNF SCSLCSYTFA YRTQLERHMT SHKSGRDQRH VTQSGCNRKF 
KCTECGKAFK YKHHLKEHLR IHSGEKPYEC PNCKKRFSHS GSYSSHISSK KCISLIPVNG 
RPRTGLKTSQ CSSPSLSASP GSPTRPQIRQ KIENKPLQEQ LSVNQIKTEP VDYEFKPIVV 
ASGINCSTPL QNGVFTGGGP LQATSSPQGM VQAVVLPTVG LVSPISINLS DIQNVLKVAV 
DGNVIRQVLE NNQANLASKE QETINASPIQ QGGHSVISAI SLPLVDQDGT TKIIINYSLE 
QPSQLQVVPQ NLKKENPVAT NSCKSEKLPE DLTVKSEKDK SFEGGVNDST CLLCDDCPGD 
INALPELKHY DLKQPTQPPP LPAAEAEKPE SSVSSATGDG NLSPSQPPLK NLLSLLKAYY 
ALNAQPSAEE LSKIADSVNL PLDVVKKWFE KMQAGQISVQ SSEPSSPEPG KVNIPAKNND 
QPQSANANEP QDSTVNLQSP LKMTNSPVLP VGSTTNGSRS STPSPSPLNL SSSRNTQGYL 
YTAEGAQEEP QVEPLDLSLP KQQGELLERS TITSVYQNSV YSVQEEPLNL SCAKKEPQKD 
SCVTDSEPVV NVIPPSANPI NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ 
VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE 
NGMYACDLCD KIFQKSSSLL RHKYEHTGKR PHECGICKKA FKHKHHLIEH MRLHSGEKPY 
QCDKCGKRFS HSGSYSQHMN HRYSYCKREA EERDSTEQEE AGPEILSNEH VGARASPSQG 
DSDERESLTR EEDDDSEKEE EEEDKEMEEL QEEKECEKPQ GDEEEEEEEE EVEEEEVEEA 
ENEGEEAKTE GLMKDDRAES QASSLGQKVG ESSEQVSEEK TNEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.