Details for: ZEB1
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: photoreceptor cell (CL0000210)
Fold Change: 4.23
Marker Score: 3188 - Cell Name: stellate neuron (CL0000122)
Fold Change: 3.81
Marker Score: 20442 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 3.8
Marker Score: 19929 - Cell Name: contractile cell (CL0000183)
Fold Change: 3.77
Marker Score: 2041 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 3.68
Marker Score: 8071 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 3.66
Marker Score: 2410 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 3.55
Marker Score: 1992 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 3.49
Marker Score: 11706 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 3.48
Marker Score: 4892 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 3.44
Marker Score: 3960 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.86
Marker Score: 1660 - Cell Name: cardiac neuron (CL0010022)
Fold Change: 2.8
Marker Score: 3488 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 2.79
Marker Score: 2662 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 2.78
Marker Score: 1336 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 2.77
Marker Score: 4030.5 - Cell Name: granule cell (CL0000120)
Fold Change: 2.63
Marker Score: 19856 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 2.63
Marker Score: 56127 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 2.63
Marker Score: 681 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.59
Marker Score: 22696 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 2.56
Marker Score: 1529 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.55
Marker Score: 5867 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.54
Marker Score: 37987 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 2.45
Marker Score: 93108 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 2.42
Marker Score: 1347 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.38
Marker Score: 10997 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 2.35
Marker Score: 4521 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.34
Marker Score: 17953 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 2.31
Marker Score: 51561 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.27
Marker Score: 45234 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.26
Marker Score: 9364 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 2.24
Marker Score: 2769 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.23
Marker Score: 25090 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 2.21
Marker Score: 9240 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.2
Marker Score: 81066 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 2.17
Marker Score: 1070 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.11
Marker Score: 618 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.06
Marker Score: 19417 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 2.05
Marker Score: 5124 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.04
Marker Score: 125177 - Cell Name: decidual cell (CL2000002)
Fold Change: 2.03
Marker Score: 8745 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 2.01
Marker Score: 2434 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2
Marker Score: 7723 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.99
Marker Score: 1311 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.94
Marker Score: 20037 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 1.9
Marker Score: 1110 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.88
Marker Score: 2009 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.85
Marker Score: 15874 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.84
Marker Score: 17514 - Cell Name: fat cell (CL0000136)
Fold Change: 1.81
Marker Score: 1009 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.78
Marker Score: 5087 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 1.77
Marker Score: 668 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.76
Marker Score: 1025 - Cell Name: neuron (CL0000540)
Fold Change: 1.72
Marker Score: 7015 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 1.72
Marker Score: 4046 - Cell Name: bronchus fibroblast of lung (CL2000093)
Fold Change: 1.71
Marker Score: 2353 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 1.65
Marker Score: 2223 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 1.64
Marker Score: 637 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.64
Marker Score: 630 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.63
Marker Score: 1414 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.63
Marker Score: 1736 - Cell Name: thymocyte (CL0000893)
Fold Change: 1.61
Marker Score: 1688 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.6
Marker Score: 835 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.59
Marker Score: 2456 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.58
Marker Score: 663 - Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 1.58
Marker Score: 2055 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.54
Marker Score: 1121 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.5
Marker Score: 3001 - Cell Name: germ cell (CL0000586)
Fold Change: 1.5
Marker Score: 2625 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.5
Marker Score: 476 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 1.48
Marker Score: 490 - Cell Name: endothelial cell (CL0000115)
Fold Change: 1.48
Marker Score: 1326 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 1.48
Marker Score: 407 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.45
Marker Score: 1449 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 1.44
Marker Score: 366 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.4
Marker Score: 441 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: 1.39
Marker Score: 1054 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.38
Marker Score: 521 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.38
Marker Score: 8879 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.38
Marker Score: 46840 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 1.36
Marker Score: 327 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.36
Marker Score: 4834.5 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.35
Marker Score: 1267 - Cell Name: endocardial cell (CL0002350)
Fold Change: 1.34
Marker Score: 760 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.34
Marker Score: 487 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.34
Marker Score: 420 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 1.32
Marker Score: 1478 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 1.28
Marker Score: 637.5 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.28
Marker Score: 5512 - Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 1.27
Marker Score: 309 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 1.26
Marker Score: 6758 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.24
Marker Score: 19438 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.22
Marker Score: 387 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 1.22
Marker Score: 283 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.2
Marker Score: 582 - Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 1.18
Marker Score: 739 - Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 1.18
Marker Score: 1265 - Cell Name: keratocyte (CL0002363)
Fold Change: 1.17
Marker Score: 270 - Cell Name: vein endothelial cell (CL0002543)
Fold Change: 1.17
Marker Score: 1059 - Cell Name: skeletal muscle satellite cell (CL0000594)
Fold Change: 1.16
Marker Score: 778 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1.16
Marker Score: 732
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Other Information
Genular Protein ID: 3793996728
Symbol: ZEB1_HUMAN
Name: Negative regulator of IL2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8138542
Title: Transcription factors positively and negatively regulating the Na,K-ATPase alpha 1 subunit gene.
PubMed ID: 8138542
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1840704
Title: Identification of a zinc finger protein that inhibits IL-2 gene expression.
PubMed ID: 1840704
PubMed ID: 16252232
Title: Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells.
PubMed ID: 16252232
DOI: 10.1086/497348
PubMed ID: 16061479
Title: Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.
PubMed ID: 16061479
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19935649
Title: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
PubMed ID: 19935649
DOI: 10.1038/ncb1998
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20175752
Title: ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus.
PubMed ID: 20175752
DOI: 10.1042/bj20091578
PubMed ID: 20418909
Title: ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.
PubMed ID: 20418909
DOI: 10.1038/onc.2010.102
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 20036349
Title: Missense mutations in TCF8 cause late-onset Fuchs corneal dystrophy and interact with FCD4 on chromosome 9p.
PubMed ID: 20036349
PubMed ID: 23599324
Title: Mutational spectrum of the ZEB1 gene in corneal dystrophies supports a genotype-phenotype correlation.
PubMed ID: 23599324
PubMed ID: 25190660
Title: Functional impact of ZEB1 mutations associated with posterior polymorphous and Fuchs' endothelial corneal dystrophies.
PubMed ID: 25190660
Sequence Information:
- Length: 1124
- Mass: 124074
- Checksum: 0A2714CC37C848D1
- Sequence:
MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDRKEG QEILGPEAQA DEAGCTVKDD ECESDAENEQ NHDPNVEEFL QQQDTAVIFP EAPEEDQRQG TPEASGHDEN GTPDAFSQLL TCPYCDRGYK RFTSLKEHIK YRHEKNEDNF SCSLCSYTFA YRTQLERHMT SHKSGRDQRH VTQSGCNRKF KCTECGKAFK YKHHLKEHLR IHSGEKPYEC PNCKKRFSHS GSYSSHISSK KCISLIPVNG RPRTGLKTSQ CSSPSLSASP GSPTRPQIRQ KIENKPLQEQ LSVNQIKTEP VDYEFKPIVV ASGINCSTPL QNGVFTGGGP LQATSSPQGM VQAVVLPTVG LVSPISINLS DIQNVLKVAV DGNVIRQVLE NNQANLASKE QETINASPIQ QGGHSVISAI SLPLVDQDGT TKIIINYSLE QPSQLQVVPQ NLKKENPVAT NSCKSEKLPE DLTVKSEKDK SFEGGVNDST CLLCDDCPGD INALPELKHY DLKQPTQPPP LPAAEAEKPE SSVSSATGDG NLSPSQPPLK NLLSLLKAYY ALNAQPSAEE LSKIADSVNL PLDVVKKWFE KMQAGQISVQ SSEPSSPEPG KVNIPAKNND QPQSANANEP QDSTVNLQSP LKMTNSPVLP VGSTTNGSRS STPSPSPLNL SSSRNTQGYL YTAEGAQEEP QVEPLDLSLP KQQGELLERS TITSVYQNSV YSVQEEPLNL SCAKKEPQKD SCVTDSEPVV NVIPPSANPI NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE NGMYACDLCD KIFQKSSSLL RHKYEHTGKR PHECGICKKA FKHKHHLIEH MRLHSGEKPY QCDKCGKRFS HSGSYSQHMN HRYSYCKREA EERDSTEQEE AGPEILSNEH VGARASPSQG DSDERESLTR EEDEDSEKEE EEEDKEMEEL QEEKECEKPQ GDEEEEEEEE EVEEEEVEEA ENEGEEAKTE GLMKDDRAES QASSLGQKVG ESSEQVSEEK TNEA
Genular Protein ID: 2696943909
Symbol: B4DGU2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 906
- Mass: 99336
- Checksum: C0D6C7726A054262
- Sequence:
MTSHKSGRDQ RHVTQSGCNR KFKCTECGKA FKYKHHLKEH LRIHSGEKPY ECPNCKKRFS HSGSYSSHIS SKKCISLIPV NGRPRTGLKT SQCSSPSLSA SPGSPTRPQI RQKIENKPLQ EQLSVNQIKT EPVDYEFKPI VVASGINCST PLQNGVFTGG GPLQATSSPQ GMVQAVVLPT VGLVSPISIN LSDIQNVLKV AVDGNVIRQV LENNQANLAS KEQEIINASP IQQGGHSVIS AISLPLVDQD GTTKIIINYS LEQPSQLQVV PQNLKKENPV ATNSCKSEKL PEDLTVKSEK DKSFEGGVND STCLLCDDCP GDINALPELK HYDLKQPTQP PPLPAAEAEK PESSVSSATG DGNLSPSQPP LKNLLSLLKA YYALNAQPSA EELSKIADSV NLPLDVVKKW FEKMQAGQIS VQSSEPSSPE PGKVNIPAKN NDQPQSANAN EPQDSTVNLQ SPLKMTNSPV LPVGSTTNGS RSSTPSPSPL NLSSSRNTQG YLYTAEGAQE EPQVEPLDLS LPKQQGELLE RSTITSVYQN SVYSVQEEPL NLSCAKKEPQ KDSCVTDSEP VVNVIPPSAN PINIAIPTVT AQLPTIVAIA DQNSVPCLRA LAANKQTILI PQVAYTYSTT VSPAVQEPPL KVIQPNGNQD ERQDTSSEGV SNVEDQNDSD STPPKKKMRK TENGMYACDL CDKIFQKSSS LLRHKYEHTG KRPHECGICK KAFKHKHHLI EHMRLHSGEK PYQCDKCGKR FSHSGSYSQH MNHRYSYCKR EAEERDSTEQ EEAGPEILSN EHVGARASPS QGDSDERESL TREEDEDSEK EEEEEDKEME ELQEEKECEK PQGDEEEEEE EEEVEEEEVE EAENEGEEAK TEGLMKDDRA ESQASSLGQK VGESSEQVSE EKTNEA
Genular Protein ID: 578465824
Symbol: B2RBI8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1124
- Mass: 124060
- Checksum: 109715DD36D859D0
- Sequence:
MADGPRCKRR KQANPRRNNV TNYNTVVETN SDSDDEDKLH IVEEESVTDA ADCEGVPEDD LPTDQTVLPG RSSEREGNAK NCWEDDRKEG QEILGPEAQA DEAGCTVKDD ECESDAENEQ NHDPNVEEFL QQQDTAVIFP EAPEEDQRQG TPEASGHDEN GTPDAFSQLL TCPYCDRGYK RFTSLKEHIK YRHEKNEDNF SCSLCSYTFA YRTQLERHMT SHKSGRDQRH VTQSGCNRKF KCTECGKAFK YKHHLKEHLR IHSGEKPYEC PNCKKRFSHS GSYSSHISSK KCISLIPVNG RPRTGLKTSQ CSSPSLSASP GSPTRPQIRQ KIENKPLQEQ LSVNQIKTEP VDYEFKPIVV ASGINCSTPL QNGVFTGGGP LQATSSPQGM VQAVVLPTVG LVSPISINLS DIQNVLKVAV DGNVIRQVLE NNQANLASKE QETINASPIQ QGGHSVISAI SLPLVDQDGT TKIIINYSLE QPSQLQVVPQ NLKKENPVAT NSCKSEKLPE DLTVKSEKDK SFEGGVNDST CLLCDDCPGD INALPELKHY DLKQPTQPPP LPAAEAEKPE SSVSSATGDG NLSPSQPPLK NLLSLLKAYY ALNAQPSAEE LSKIADSVNL PLDVVKKWFE KMQAGQISVQ SSEPSSPEPG KVNIPAKNND QPQSANANEP QDSTVNLQSP LKMTNSPVLP VGSTTNGSRS STPSPSPLNL SSSRNTQGYL YTAEGAQEEP QVEPLDLSLP KQQGELLERS TITSVYQNSV YSVQEEPLNL SCAKKEPQKD SCVTDSEPVV NVIPPSANPI NIAIPTVTAQ LPTIVAIADQ NSVPCLRALA ANKQTILIPQ VAYTYSTTVS PAVQEPPLKV IQPNGNQDER QDTSSEGVSN VEDQNDSDST PPKKKMRKTE NGMYACDLCD KIFQKSSSLL RHKYEHTGKR PHECGICKKA FKHKHHLIEH MRLHSGEKPY QCDKCGKRFS HSGSYSQHMN HRYSYCKREA EERDSTEQEE AGPEILSNEH VGARASPSQG DSDERESLTR EEDDDSEKEE EEEDKEMEEL QEEKECEKPQ GDEEEEEEEE EVEEEEVEEA ENEGEEAKTE GLMKDDRAES QASSLGQKVG ESSEQVSEEK TNEA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.