Details for: KALRN

Gene ID: 8997

Symbol: KALRN

Ensembl ID: ENSG00000160145

Description: kalirin RhoGEF kinase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 6.26
    Marker Score: 37,626
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 5.83
    Marker Score: 196,785
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 5.14
    Marker Score: 4,437
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 4.92
    Marker Score: 3,707
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 4.39
    Marker Score: 14,709
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 4.21
    Marker Score: 2,281
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.85
    Marker Score: 8,448
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 3.83
    Marker Score: 2,223
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 3.77
    Marker Score: 5,302
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.42
    Marker Score: 15,813
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 3.41
    Marker Score: 1,637
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 3.17
    Marker Score: 1,777
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.09
    Marker Score: 54,875
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 3.03
    Marker Score: 8,639
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 3.02
    Marker Score: 5,079
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.95
    Marker Score: 63,016
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.93
    Marker Score: 65,554
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.92
    Marker Score: 3,925
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.92
    Marker Score: 3,528
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.89
    Marker Score: 3,329
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.86
    Marker Score: 21,955
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.85
    Marker Score: 6,560
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.83
    Marker Score: 42,367
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.83
    Marker Score: 56,315
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.83
    Marker Score: 894
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.79
    Marker Score: 11,695
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.72
    Marker Score: 1,046
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.71
    Marker Score: 102,852
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 2.65
    Marker Score: 2,834
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.6
    Marker Score: 4,999
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.57
    Marker Score: 10,635
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.4
    Marker Score: 8,531
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.37
    Marker Score: 87,398
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.34
    Marker Score: 9,041
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.25
    Marker Score: 1,479
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.23
    Marker Score: 2,127
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.2
    Marker Score: 20,655
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.18
    Marker Score: 1,303
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 2.16
    Marker Score: 11,326
  • Cell Name: granule cell (CL0000120)
    Fold Change: 2.15
    Marker Score: 16,233
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.13
    Marker Score: 1,248
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.13
    Marker Score: 1,843
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.12
    Marker Score: 3,087
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 2.08
    Marker Score: 653
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.08
    Marker Score: 127,975
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 2.06
    Marker Score: 2,564
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.02
    Marker Score: 5,050
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.98
    Marker Score: 1,099
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.96
    Marker Score: 8,000
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.96
    Marker Score: 822
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 1.95
    Marker Score: 1,020
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.93
    Marker Score: 19,978
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.93
    Marker Score: 18,321
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 1.9
    Marker Score: 576
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.88
    Marker Score: 16,151
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.76
    Marker Score: 663
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.7
    Marker Score: 9,141
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.65
    Marker Score: 2,543
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.59
    Marker Score: 3,232
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.58
    Marker Score: 820
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.58
    Marker Score: 3,728
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.55
    Marker Score: 864
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.51
    Marker Score: 417
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,757
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.37
    Marker Score: 1,697
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.36
    Marker Score: 21,341
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.34
    Marker Score: 660
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.3
    Marker Score: 759
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.28
    Marker Score: 771
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.25
    Marker Score: 5,193
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.24
    Marker Score: 340
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.24
    Marker Score: 2,958
  • Cell Name: bipolar neuron (CL0000103)
    Fold Change: 1.21
    Marker Score: 407
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 1.21
    Marker Score: 686
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 1.21
    Marker Score: 313
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.16
    Marker Score: 3,808
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.12
    Marker Score: 1,353
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.11
    Marker Score: 269
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.11
    Marker Score: 377
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.08
    Marker Score: 4,485
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.06
    Marker Score: 671
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 1.05
    Marker Score: 502
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.04
    Marker Score: 273
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.03
    Marker Score: 785
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,772
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,997
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.99
    Marker Score: 4,261
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,405
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.98
    Marker Score: 310
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.97
    Marker Score: 607
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 499
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.97
    Marker Score: 1,287
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 454
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,411
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.95
    Marker Score: 1,537
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.92
    Marker Score: 994
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.92
    Marker Score: 5,926
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.92
    Marker Score: 1,297
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,732
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.9
    Marker Score: 366

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **RhoGEF Kinase**: KALRN belongs to the Rho GTPase-activating protein (RhoGAP) family, which regulates the activity of small GTPases, including RhoA, Rac1, and Cdc42. These GTPases are crucial for various cellular processes, including cytoskeleton reorganization, cell migration, and signaling. 2. **Axon Guidance**: KALRN has been implicated in axon guidance, a process essential for neuronal development and connectivity. The gene's product interacts with other proteins to regulate the activity of small GTPases, influencing the formation of axonal connections. 3. **Immune Response**: KALRN is significantly expressed in immune cells, including fibroblasts of cardiac tissue, Purkinje cells, and chromaffin cells. The gene's product modulates immune responses by regulating the activity of signaling pathways, including the NF-κB and MAPK pathways. **Pathways and Functions:** 1. **Actin Cytoskeleton**: KALRN regulates the activity of small GTPases, which in turn modulate the actin cytoskeleton. This process is essential for cell migration, shape changes, and intracellular signaling. 2. **Eph-ephrin Signaling**: KALRN interacts with Eph receptors and ephrin ligands to regulate axon guidance and neuronal development. The gene's product modulates the activity of small GTPases, influencing the formation of axonal connections. 3. **Death Receptor Signaling**: KALRN is involved in death receptor signaling, a process that regulates apoptosis (programmed cell death). The gene's product modulates the activity of signaling pathways, including the NF-κB and MAPK pathways. 4. **Extracellular Exosome**: KALRN is involved in the regulation of extracellular exosome-mediated signaling, a process that involves the transfer of signaling molecules between cells. **Clinical Significance:** 1. **Neurological Disorders**: Alterations in KALRN expression have been linked to various neurological disorders, including autism spectrum disorder, schizophrenia, and neurodegenerative diseases such as Alzheimer's and Parkinson's. 2. **Immune-Mediated Diseases**: KALRN's involvement in immune response pathways suggests that alterations in the gene's expression may contribute to immune-mediated diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer**: KALRN's role in cell migration and invasion suggests that the gene may be involved in cancer progression and metastasis. In conclusion, Kalirin RhoGEF kinase plays a multifaceted role in immune response, axon guidance, and neuronal development. Its involvement in various signaling pathways and its clinical significance highlight the importance of further research into the gene's function and its potential implications for human disease.

Genular Protein ID: 3233380870

Symbol: KALRN_HUMAN

Name: Huntingtin-associated protein-interacting protein

UniProtKB Accession Codes:

O60229 A8MSI4 C9JQ37 J3QSW6 Q6ZN45 Q8TBQ5 Q9NSZ4 Q9Y2A5

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 9 CTD 1 ChEBI 13 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 3 EMBL 14 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 20 Gene3D 7 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 24 KEGG 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 12 PIR 1 PRO 1 PROSITE 9 PROSITE-ProRule 8 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 8 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 8 RefSeq 13 Rhea 6 SAM 1 SIGNOR 1 SMART 9 SMR 1 STRING 1 SUPFAM 7 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 4 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9285789

Title: Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.

PubMed ID: 9285789

DOI: 10.1093/hmg/6.9.1519

PubMed ID: 10023074

Title: Duet is a novel serine/threonine kinase with Dbl-homology (DH) and pleckstrin-homology (PH) domains.

PubMed ID: 10023074

DOI: 10.1016/s0378-1119(98)00605-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19807924

Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

PubMed ID: 19807924

DOI: 10.1186/1471-2172-10-53

PubMed ID: 22738176

Title: Structural organization of the nine spectrin repeats of Kalirin.

PubMed ID: 22738176

DOI: 10.1021/bi300583s

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 2986
  • Mass: 340261
  • Checksum: EA7B559A9E4AFFA0
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI ESLFHATSLQ KTHQSALQVQ 
QKAEVLLQAG HYDADAIREC AEKVALHWQQ LMLKMEDRLK LVNASVAFYK TSEQVCSVLE 
SLEQEYRRDE DWCGGRDKLG PAAEIDHVIP LISKHLEQKE AFLKACTLAR RNAEVFLKYI 
HRNNVSMPSV ASHTRGPEQQ VKAILSELLQ RENRVLHFWT LKKRRLDQCQ QYVVFERSAK 
QALDWIQETG EFYLSTHTST GETTEETQEL LKEYGEFRVP AKQTKEKVKL LIQLADSFVE 
KGHIHATEIR KWVTTVDKHY RDFSLRMGKY RYSLEKALGV NTEDNKDLEL DIIPASLSDR 
EVKLRDANHE VNEEKRKSAR KKEFIMAELL QTEKAYVRDL HECLETYLWE MTSGVEEIPP 
GILNKEHIIF GNIQEIYDFH NNIFLKELEK YEQLPEDVGH CFVTWADKFQ MYVTYCKNKP 
DSNQLILEHA GTFFDEIQQR HGLANSISSY LIKPVQRITK YQLLLKELLT CCEEGKGELK 
DGLEVMLSVP KKANDAMHVS MLEGFDENLD VQGELILQDA FQVWDPKSLI RKGRERHLFL 
FEISLVFSKE IKDSSGHTKY VYKNKLLTSE LGVTEHVEGD PCKFALWSGR TPSSDNKTVL 
KASNIETKQE WIKNIREVIQ ERIIHLKGAL KEPLQLPKTP AKQRNNSKRD GVEDIDSQGD 
GSSQPDTISI ASRTSQNTVD SDKLSGGCEL TVVLQDFSAG HSSELTIQVG QTVELLERPS 
ERPGWCLVRT TERSPPLEGL VPSSALCISH SRSSVEMDCF FPLVKDAYSH SSSENGGKSE 
SVANLQAQPS LNSIHSSPGP KRSTNTLKKW LTSPVRRLNS GKADGNIKKQ KKVRDGRKSF 
DLGSPKPGDE TTPQGDSADE KSKKGWGEDE PDEESHTPLP PPMKIFDNDP TQDEMSSSLL 
AARQASTEVP TAADLVNAIE KLVKNKLSLE GSSYRGSLKD PAGCLNEGMA PPTPPKNPEE 
EQKAKALRGR MFVLNELVQT EKDYVKDLGI VVEGFMKRIE EKGVPEDMRG KDKIVFGNIH 
QIYDWHKDFF LAELEKCIQE QDRLAQLFIK HERKLHIYVW YCQNKPRSEY IVAEYDAYFE 
EVKQEINQRL TLSDFLIKPI QRITKYQLLL KDFLRYSEKA GLECSDIEKA VELMCLVPKR 
CNDMMNLGRL QGFEGTLTAQ GKLLQQDTFY VIELDAGMQS RTKERRVFLF EQIVIFSELL 
RKGSLTPGYM FKRSIKMNYL VLEENVDNDP CKFALMNRET SERVVLQAAN ADIQQAWVQD 
INQVLETQRD FLNALQSPIE YQRKERSTAV MRSQPARLPQ ASPRPYSSVP AGSEKPPKGS 
SYNPPLPPLK ISTSNGSPGF EYHQPGDKFE ASKQNDLGGC NGTSSMAVIK DYYALKENEI 
CVSQGEVVQV LAVNQQNMCL VYQPASDHSP AAEGWVPGSI LAPLTKATAA ESSDGSIKKS 
CSWHTLRMRK RAEVENTGKN EATGPRKPKD ILGNKVSVKE TNSSEESECD DLDPNTSMEI 
LNPNFIQEVA PEFLVPLVDV TCLLGDTVIL QCKVCGRPKP TITWKGPDQN ILDTDNSSAT 
YTVSSCDSGE ITLKICNLMP QDSGIYTCIA TNDHGTTSTS ATVKVQGVPA APNRPIAQER 
SCTSVILRWL PPSSTGNCTI SGYTVEYREE GSQIWQQSVA STLDTYLVIE DLSPGCPYQF 
RVSASNPWGI SLPSEPSEFV RLPEYDAAAD GATISWKENF DSAYTELNEI GRGRFSIVKK 
CIHKATRKDV AVKFVSKKMK KKEQAAHEAA LLQHLQHPQY ITLHDTYESP TSYILILELM 
DDGRLLDYLM NHDELMEEKV AFYIRDIMEA LQYLHNCRVA HLDIKPENLL IDLRIPVPRV 
KLIDLEDAVQ ISGHFHIHHL LGNPEFAAPE VIQGIPVSLG TDIWSIGVLT YVMLSGVSPF 
LDESKEETCI NVCRVDFSFP HEYFCGVSNA ARDFINVILQ EDFRRRPTAA TCLQHPWLQP 
HNGSYSKIPL DTSRLACFIE RRKHQNDVRP IPNVKSYIVN RVNQGT

Genular Protein ID: 3181694245

Symbol: C9IZQ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9IZQ6

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 EMBL 9 EPD 1 Ensembl 2 GO 1 Gene3D 4 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 9 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1654
  • Mass: 191244
  • Checksum: 909B73D9BEE7EA36
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI EKTHQSALQV QQKAEVLLQA 
GHYDADAIRE CAEKVALHWQ QLMLKMEDRL KLVNASVAFY KTSEQVCSVL ESLEQEYRRD 
EDWCGGRDKL GPAAEIDHVI PLISKHLEQK EAFLKACTLA RRNAEVFLKY IHRNNVSMPS 
VASHTRGPEQ QVKAILSELL QRENRVLHFW TLKKRRLDQC QQYVVFERSA KQALDWIQET 
GEFYLSTHTS TGETTEETQE LLKEYGEFRV PAKQTKEKVK LLIQLADSFV EKGHIHATEI 
RKWVTTVDKH YRDFSLRMGK YRYSLEKALG VNTEDNKDLE LDIIPASLSD REVKLRDANH 
EVNEEKRKSA RKKEFIMAEL LQTEKAYVRD LHECLETYLW EMTSGVEEIP PGILNKEHII 
FGNIQEIYDF HNNIFLKELE KYEQLPEDVG HCFVTWADKF QMYVTYCKNK PDSNQLILEH 
AGTFFDEIQQ RHGLANSISS YLIKPVQRIT KYQLLLKELL TCCEEGKGEL KDGLEVMLSV 
PKKANDAMHV SMLEGFDENL DVQGELILQD AFQVWDPKSL IRKGRERHLF LFEISLVFSK 
EIKDSSGHTK YVYKNKLLTS ELGVTEHVEG DPCKFALWSG RTPSSDNKTV LKASNIETKQ 
EWIKNIREVI QERIIHLKGA LKEPLQLPKT PAKQRNNSKR DGVEDIDSQG DGSSQPDTIS 
IASRTSQNTV DSDKDGNLVP RWHLGPGDPF STYV

Genular Protein ID: 1516920928

Symbol: A0A804HKT9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKT9

Database IDs:

ARBA 1 Bgee 1 CDD 4 CTD 1 EMBL 7 EPD 1 Ensembl 2 GO 1 Gene3D 4 GeneTree 1 HGNC 1 InterPro 9 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 6 PeptideAtlas 1 Pfam 4 Proteomes 2 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 4

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1613
  • Mass: 186494
  • Checksum: CE1B7999AD67DAB5
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI ESLFHATSLQ KTHQSALQVQ 
QKAEVLLQAG HYDADAIREC AEKVALHWQQ LMLKMEDRLK LVNASVAFYK TSEQACTLAR 
RNAEVFLKYI HRNNVSMPSV ASHTRGPEQQ VKAILSELLQ RENRVLHFWT LKKRRLDQCQ 
QYVVFERSAK QALDWIQETG EFYLSTHTST GETTEETQEL LKEYGEFRVP AKQTKEKVKL 
LIQLADSFVE KGHIHATEIR KWVTTVDKHY RDFSLRMGKY RYSLEKALGV NTEDNKDLEL 
DIIPASLSDR EVKLRDANHE VNEEKRKSAR KKEFIMAELL QTEKAYVRDL HECLETYLWE 
MTSGVEEIPP GILNKEHIIF GNIQEIYDFH NNIFLKELEK YEQLPEDVGH CFVTWADKFQ 
MYVTYCKNKP DSNQLILEHA GTFFDEIQQR HGLANSISSY LIKPVQRITK YQLLLKELLT 
CCEEGKGELK DGLEVMLSVP KKANDAMHVS MLEGFDENLD VQGELILQDA FQVWDPKSLI 
RKGRERHLFL FEISLVFSKE IKDSSGHTKY VYKNKLLTSE LGVTEHVEGD PCKFALWSGR 
TPSSDNKTVL KASNIETKQE WIKNIREVIQ ERIIHLKGAL KEPLQLPKTP AKQRNNSKRD 
GVEDIDSQGD GSSQPDTISI ASRTSQNTVD SDKDGNLVPR WHLGPGDPFS TYV

Genular Protein ID: 3260308785

Symbol: A0A804HKJ7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKJ7

Database IDs:

ARBA 1 AlphaFoldDB 1 Bgee 1 CDD 3 CTD 1 EMBL 7 Ensembl 2 GO 3 Gene3D 3 GeneTree 1 HGNC 1 InterPro 7 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 3

Citations:

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 709
  • Mass: 79284
  • Checksum: 2ABED20C3B94DEF5
  • Sequence:
    • MKGGDRAYTR GPSLGWLFAK CCCCFPCRDA YSHSSSENGG KSESVANLQA QPSLNSIHSS 
PGPKRSTNTL KKWLTSPVRR LNSGKADGNI KKQKKVRDGR KSFDLGSPKP GDETTPQGDS 
ADESKKGWGE DEPDEESHTP LPPPMKIFDN DPTQDEMSSS LLAARQASTE VPTAADLVNA 
IEKLVKNKLS LEGSSYRGSL KDPAGCLNEG MAPPTPPKNP EEEQKAKALR GRMFVLNELV 
QTEKDYVKDL GIVVEGFMKR IEEKGVPEDM RGKDKIVFGN IHQIYDWHKD FFLAELEKCI 
QEQDRLAQLF IKHERKLHIY VWYCQNKPRS EYIVAEYDAY FEEVKQEINQ RLTLSDFLIK 
PIQRITKYQL LLKGPYWISF SRGEKIVSGG PWIQVDPSQT KAVELMCLVP KRCNDMMNLG 
RLQGFEGTLT AQGKLLQQDT FYVIELDAGM QSRTKERRVF LFEQIVIFSE LLRKGSLTPG 
YMFKRSIKMN YLVLEENVDN DPCKFALMNR ETSERVVLQA ANADIQQAWV QDINQVLETQ 
RDFLNALQSP IEYQRKERST AVMRSQPARL PQASPRPYSS VPAGSEKPPK GSSYNPPLPP 
LKISTSNGSP GFEYHQPGDK FEASKNDLGG CNGTSSMAVI KDYYALKENE ICVSQGEVVQ 
VLAVNQQNMC LVYQPASDHS PAAEGWVPGS ILAPLTKATA AESSDGSIK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.