Details for: KALRN

Gene ID: 8997

Symbol: KALRN

Ensembl ID: ENSG00000160145

Description: kalirin RhoGEF kinase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 613.1336
    Cell Significance Index: -95.3700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 378.9770
    Cell Significance Index: -96.1300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 193.2549
    Cell Significance Index: -91.2400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 74.8160
    Cell Significance Index: -71.4300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 24.1964
    Cell Significance Index: -95.4800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 21.4202
    Cell Significance Index: -46.8800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 6.8491
    Cell Significance Index: 384.3400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 6.8145
    Cell Significance Index: 163.4300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 6.2999
    Cell Significance Index: 423.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 5.6709
    Cell Significance Index: 2573.8600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.4916
    Cell Significance Index: 337.5400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 5.4161
    Cell Significance Index: 154.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 4.5930
    Cell Significance Index: 203.1600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 4.5313
    Cell Significance Index: 1625.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 4.4856
    Cell Significance Index: 169.8600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 4.0004
    Cell Significance Index: 102.8300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.8368
    Cell Significance Index: 769.6600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.7243
    Cell Significance Index: 285.8000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.2781
    Cell Significance Index: 2267.2800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 3.2428
    Cell Significance Index: 46.6400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.7169
    Cell Significance Index: 59.4900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.6674
    Cell Significance Index: 35.5800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.8898
    Cell Significance Index: 54.4500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.4226
    Cell Significance Index: 30.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.0315
    Cell Significance Index: 107.4000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.9862
    Cell Significance Index: 21.0800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9262
    Cell Significance Index: 150.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7875
    Cell Significance Index: 156.2800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6851
    Cell Significance Index: 74.5200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5208
    Cell Significance Index: 980.6900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4089
    Cell Significance Index: 40.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.3662
    Cell Significance Index: 563.7300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.3158
    Cell Significance Index: 582.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1548
    Cell Significance Index: 210.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1403
    Cell Significance Index: 4.9300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0979
    Cell Significance Index: 43.3000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0693
    Cell Significance Index: 13.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0337
    Cell Significance Index: 21.3800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0386
    Cell Significance Index: -0.4200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0943
    Cell Significance Index: -69.8700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.1082
    Cell Significance Index: -2.6400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1090
    Cell Significance Index: -79.9400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1116
    Cell Significance Index: -60.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1376
    Cell Significance Index: -104.1200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1651
    Cell Significance Index: -103.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1652
    Cell Significance Index: -93.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1869
    Cell Significance Index: -27.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.2115
    Cell Significance Index: -38.1200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.2360
    Cell Significance Index: -3.0600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.2602
    Cell Significance Index: -2.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2780
    Cell Significance Index: -79.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3075
    Cell Significance Index: -35.8400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3468
    Cell Significance Index: -44.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3531
    Cell Significance Index: -60.2900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4112
    Cell Significance Index: -10.2800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.4133
    Cell Significance Index: -5.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4415
    Cell Significance Index: -60.6300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4622
    Cell Significance Index: -9.1400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4748
    Cell Significance Index: -100.0100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.4972
    Cell Significance Index: -61.1300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5724
    Cell Significance Index: -73.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6683
    Cell Significance Index: -21.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7366
    Cell Significance Index: -84.4000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.7564
    Cell Significance Index: -89.2000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.7601
    Cell Significance Index: -34.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.8065
    Cell Significance Index: -82.3800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8225
    Cell Significance Index: -58.1700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8374
    Cell Significance Index: -26.6700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.9095
    Cell Significance Index: -13.0300
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.9220
    Cell Significance Index: -9.5500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.9808
    Cell Significance Index: -19.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0182
    Cell Significance Index: -80.6400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.1023
    Cell Significance Index: -82.1600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.1342
    Cell Significance Index: -59.0800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.1558
    Cell Significance Index: -32.3000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.1681
    Cell Significance Index: -54.9000
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: -1.2914
    Cell Significance Index: -9.9100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.2985
    Cell Significance Index: -19.1700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.3056
    Cell Significance Index: -27.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.3130
    Cell Significance Index: -42.0600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.3298
    Cell Significance Index: -85.7900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.3577
    Cell Significance Index: -63.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.4342
    Cell Significance Index: -30.5500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.4515
    Cell Significance Index: -88.9900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.5387
    Cell Significance Index: -80.7900
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -1.5671
    Cell Significance Index: -14.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.5837
    Cell Significance Index: -42.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.6091
    Cell Significance Index: -83.5900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.6866
    Cell Significance Index: -36.4400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6959
    Cell Significance Index: -59.4100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.7194
    Cell Significance Index: -21.4400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.7467
    Cell Significance Index: -110.0900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.8427
    Cell Significance Index: -45.9700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.8670
    Cell Significance Index: -23.5600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -1.8916
    Cell Significance Index: -20.8700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.9655
    Cell Significance Index: -22.9300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -2.1797
    Cell Significance Index: -68.9400
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -2.2046
    Cell Significance Index: -28.2700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -2.2157
    Cell Significance Index: -33.2000
  • Cell Name: neuron (CL0000540)
    Fold Change: -2.2481
    Cell Significance Index: -21.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **RhoGEF Kinase**: KALRN belongs to the Rho GTPase-activating protein (RhoGAP) family, which regulates the activity of small GTPases, including RhoA, Rac1, and Cdc42. These GTPases are crucial for various cellular processes, including cytoskeleton reorganization, cell migration, and signaling. 2. **Axon Guidance**: KALRN has been implicated in axon guidance, a process essential for neuronal development and connectivity. The gene's product interacts with other proteins to regulate the activity of small GTPases, influencing the formation of axonal connections. 3. **Immune Response**: KALRN is significantly expressed in immune cells, including fibroblasts of cardiac tissue, Purkinje cells, and chromaffin cells. The gene's product modulates immune responses by regulating the activity of signaling pathways, including the NF-κB and MAPK pathways. **Pathways and Functions:** 1. **Actin Cytoskeleton**: KALRN regulates the activity of small GTPases, which in turn modulate the actin cytoskeleton. This process is essential for cell migration, shape changes, and intracellular signaling. 2. **Eph-ephrin Signaling**: KALRN interacts with Eph receptors and ephrin ligands to regulate axon guidance and neuronal development. The gene's product modulates the activity of small GTPases, influencing the formation of axonal connections. 3. **Death Receptor Signaling**: KALRN is involved in death receptor signaling, a process that regulates apoptosis (programmed cell death). The gene's product modulates the activity of signaling pathways, including the NF-κB and MAPK pathways. 4. **Extracellular Exosome**: KALRN is involved in the regulation of extracellular exosome-mediated signaling, a process that involves the transfer of signaling molecules between cells. **Clinical Significance:** 1. **Neurological Disorders**: Alterations in KALRN expression have been linked to various neurological disorders, including autism spectrum disorder, schizophrenia, and neurodegenerative diseases such as Alzheimer's and Parkinson's. 2. **Immune-Mediated Diseases**: KALRN's involvement in immune response pathways suggests that alterations in the gene's expression may contribute to immune-mediated diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer**: KALRN's role in cell migration and invasion suggests that the gene may be involved in cancer progression and metastasis. In conclusion, Kalirin RhoGEF kinase plays a multifaceted role in immune response, axon guidance, and neuronal development. Its involvement in various signaling pathways and its clinical significance highlight the importance of further research into the gene's function and its potential implications for human disease.

Genular Protein ID: 3233380870

Symbol: KALRN_HUMAN

Name: Huntingtin-associated protein-interacting protein

UniProtKB Accession Codes:

O60229 A8MSI4 C9JQ37 J3QSW6 Q6ZN45 Q8TBQ5 Q9NSZ4 Q9Y2A5

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 9 CTD 1 ChEBI 13 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 3 EMBL 14 Ensembl 3 ExpressionAtlas 1 GO 20 Gene3D 7 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 25 KEGG 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 1 PRO 1 PROSITE 9 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 8 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 8 RefSeq 13 Rhea 6 SIGNOR 1 SMART 9 SMR 1 STRING 1 SUPFAM 7 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9285789

Title: Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.

PubMed ID: 9285789

DOI: 10.1093/hmg/6.9.1519

PubMed ID: 10023074

Title: Duet is a novel serine/threonine kinase with Dbl-homology (DH) and pleckstrin-homology (PH) domains.

PubMed ID: 10023074

DOI: 10.1016/s0378-1119(98)00605-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19807924

Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.

PubMed ID: 19807924

DOI: 10.1186/1471-2172-10-53

PubMed ID: 22738176

Title: Structural organization of the nine spectrin repeats of Kalirin.

PubMed ID: 22738176

DOI: 10.1021/bi300583s

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 2986
  • Mass: 340261
  • Checksum: EA7B559A9E4AFFA0
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI ESLFHATSLQ KTHQSALQVQ 
QKAEVLLQAG HYDADAIREC AEKVALHWQQ LMLKMEDRLK LVNASVAFYK TSEQVCSVLE 
SLEQEYRRDE DWCGGRDKLG PAAEIDHVIP LISKHLEQKE AFLKACTLAR RNAEVFLKYI 
HRNNVSMPSV ASHTRGPEQQ VKAILSELLQ RENRVLHFWT LKKRRLDQCQ QYVVFERSAK 
QALDWIQETG EFYLSTHTST GETTEETQEL LKEYGEFRVP AKQTKEKVKL LIQLADSFVE 
KGHIHATEIR KWVTTVDKHY RDFSLRMGKY RYSLEKALGV NTEDNKDLEL DIIPASLSDR 
EVKLRDANHE VNEEKRKSAR KKEFIMAELL QTEKAYVRDL HECLETYLWE MTSGVEEIPP 
GILNKEHIIF GNIQEIYDFH NNIFLKELEK YEQLPEDVGH CFVTWADKFQ MYVTYCKNKP 
DSNQLILEHA GTFFDEIQQR HGLANSISSY LIKPVQRITK YQLLLKELLT CCEEGKGELK 
DGLEVMLSVP KKANDAMHVS MLEGFDENLD VQGELILQDA FQVWDPKSLI RKGRERHLFL 
FEISLVFSKE IKDSSGHTKY VYKNKLLTSE LGVTEHVEGD PCKFALWSGR TPSSDNKTVL 
KASNIETKQE WIKNIREVIQ ERIIHLKGAL KEPLQLPKTP AKQRNNSKRD GVEDIDSQGD 
GSSQPDTISI ASRTSQNTVD SDKLSGGCEL TVVLQDFSAG HSSELTIQVG QTVELLERPS 
ERPGWCLVRT TERSPPLEGL VPSSALCISH SRSSVEMDCF FPLVKDAYSH SSSENGGKSE 
SVANLQAQPS LNSIHSSPGP KRSTNTLKKW LTSPVRRLNS GKADGNIKKQ KKVRDGRKSF 
DLGSPKPGDE TTPQGDSADE KSKKGWGEDE PDEESHTPLP PPMKIFDNDP TQDEMSSSLL 
AARQASTEVP TAADLVNAIE KLVKNKLSLE GSSYRGSLKD PAGCLNEGMA PPTPPKNPEE 
EQKAKALRGR MFVLNELVQT EKDYVKDLGI VVEGFMKRIE EKGVPEDMRG KDKIVFGNIH 
QIYDWHKDFF LAELEKCIQE QDRLAQLFIK HERKLHIYVW YCQNKPRSEY IVAEYDAYFE 
EVKQEINQRL TLSDFLIKPI QRITKYQLLL KDFLRYSEKA GLECSDIEKA VELMCLVPKR 
CNDMMNLGRL QGFEGTLTAQ GKLLQQDTFY VIELDAGMQS RTKERRVFLF EQIVIFSELL 
RKGSLTPGYM FKRSIKMNYL VLEENVDNDP CKFALMNRET SERVVLQAAN ADIQQAWVQD 
INQVLETQRD FLNALQSPIE YQRKERSTAV MRSQPARLPQ ASPRPYSSVP AGSEKPPKGS 
SYNPPLPPLK ISTSNGSPGF EYHQPGDKFE ASKQNDLGGC NGTSSMAVIK DYYALKENEI 
CVSQGEVVQV LAVNQQNMCL VYQPASDHSP AAEGWVPGSI LAPLTKATAA ESSDGSIKKS 
CSWHTLRMRK RAEVENTGKN EATGPRKPKD ILGNKVSVKE TNSSEESECD DLDPNTSMEI 
LNPNFIQEVA PEFLVPLVDV TCLLGDTVIL QCKVCGRPKP TITWKGPDQN ILDTDNSSAT 
YTVSSCDSGE ITLKICNLMP QDSGIYTCIA TNDHGTTSTS ATVKVQGVPA APNRPIAQER 
SCTSVILRWL PPSSTGNCTI SGYTVEYREE GSQIWQQSVA STLDTYLVIE DLSPGCPYQF 
RVSASNPWGI SLPSEPSEFV RLPEYDAAAD GATISWKENF DSAYTELNEI GRGRFSIVKK 
CIHKATRKDV AVKFVSKKMK KKEQAAHEAA LLQHLQHPQY ITLHDTYESP TSYILILELM 
DDGRLLDYLM NHDELMEEKV AFYIRDIMEA LQYLHNCRVA HLDIKPENLL IDLRIPVPRV 
KLIDLEDAVQ ISGHFHIHHL LGNPEFAAPE VIQGIPVSLG TDIWSIGVLT YVMLSGVSPF 
LDESKEETCI NVCRVDFSFP HEYFCGVSNA ARDFINVILQ EDFRRRPTAA TCLQHPWLQP 
HNGSYSKIPL DTSRLACFIE RRKHQNDVRP IPNVKSYIVN RVNQGT

Genular Protein ID: 3260308785

Symbol: A0A804HKJ7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKJ7

Database IDs:

ARBA 2 AlphaFoldDB 1 Bgee 1 CDD 3 CTD 1 DisGeNET 1 EMBL 7 Ensembl 2 GO 3 Gene3D 3 GeneTree 1 HGNC 1 InterPro 8 NCBI Taxonomy 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 709
  • Mass: 79284
  • Checksum: 2ABED20C3B94DEF5
  • Sequence:
    • MKGGDRAYTR GPSLGWLFAK CCCCFPCRDA YSHSSSENGG KSESVANLQA QPSLNSIHSS 
PGPKRSTNTL KKWLTSPVRR LNSGKADGNI KKQKKVRDGR KSFDLGSPKP GDETTPQGDS 
ADESKKGWGE DEPDEESHTP LPPPMKIFDN DPTQDEMSSS LLAARQASTE VPTAADLVNA 
IEKLVKNKLS LEGSSYRGSL KDPAGCLNEG MAPPTPPKNP EEEQKAKALR GRMFVLNELV 
QTEKDYVKDL GIVVEGFMKR IEEKGVPEDM RGKDKIVFGN IHQIYDWHKD FFLAELEKCI 
QEQDRLAQLF IKHERKLHIY VWYCQNKPRS EYIVAEYDAY FEEVKQEINQ RLTLSDFLIK 
PIQRITKYQL LLKGPYWISF SRGEKIVSGG PWIQVDPSQT KAVELMCLVP KRCNDMMNLG 
RLQGFEGTLT AQGKLLQQDT FYVIELDAGM QSRTKERRVF LFEQIVIFSE LLRKGSLTPG 
YMFKRSIKMN YLVLEENVDN DPCKFALMNR ETSERVVLQA ANADIQQAWV QDINQVLETQ 
RDFLNALQSP IEYQRKERST AVMRSQPARL PQASPRPYSS VPAGSEKPPK GSSYNPPLPP 
LKISTSNGSP GFEYHQPGDK FEASKNDLGG CNGTSSMAVI KDYYALKENE ICVSQGEVVQ 
VLAVNQQNMC LVYQPASDHS PAAEGWVPGS ILAPLTKATA AESSDGSIK

Genular Protein ID: 1516920928

Symbol: A0A804HKT9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HKT9

Database IDs:

ARBA 2 Bgee 1 CDD 4 CTD 1 DisGeNET 1 EMBL 7 Ensembl 2 GO 2 Gene3D 4 GeneTree 1 HGNC 1 InterPro 10 NCBI Taxonomy 1 PANTHER 2 PROSITE 6 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 4

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1613
  • Mass: 186494
  • Checksum: CE1B7999AD67DAB5
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI ESLFHATSLQ KTHQSALQVQ 
QKAEVLLQAG HYDADAIREC AEKVALHWQQ LMLKMEDRLK LVNASVAFYK TSEQACTLAR 
RNAEVFLKYI HRNNVSMPSV ASHTRGPEQQ VKAILSELLQ RENRVLHFWT LKKRRLDQCQ 
QYVVFERSAK QALDWIQETG EFYLSTHTST GETTEETQEL LKEYGEFRVP AKQTKEKVKL 
LIQLADSFVE KGHIHATEIR KWVTTVDKHY RDFSLRMGKY RYSLEKALGV NTEDNKDLEL 
DIIPASLSDR EVKLRDANHE VNEEKRKSAR KKEFIMAELL QTEKAYVRDL HECLETYLWE 
MTSGVEEIPP GILNKEHIIF GNIQEIYDFH NNIFLKELEK YEQLPEDVGH CFVTWADKFQ 
MYVTYCKNKP DSNQLILEHA GTFFDEIQQR HGLANSISSY LIKPVQRITK YQLLLKELLT 
CCEEGKGELK DGLEVMLSVP KKANDAMHVS MLEGFDENLD VQGELILQDA FQVWDPKSLI 
RKGRERHLFL FEISLVFSKE IKDSSGHTKY VYKNKLLTSE LGVTEHVEGD PCKFALWSGR 
TPSSDNKTVL KASNIETKQE WIKNIREVIQ ERIIHLKGAL KEPLQLPKTP AKQRNNSKRD 
GVEDIDSQGD GSSQPDTISI ASRTSQNTVD SDKDGNLVPR WHLGPGDPFS TYV

Genular Protein ID: 3181694245

Symbol: C9IZQ6_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9IZQ6

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 2 GO 2 Gene3D 4 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 4 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 1654
  • Mass: 191244
  • Checksum: 909B73D9BEE7EA36
  • Sequence:
    • MTDRFWDQWY LWYLRLLRLL DRGSFRNDGL KASDVLPILK EKVAFVSGGR DKRGGPILTF 
PARSNHDRIR QEDLRKLVTY LASVPSEDVC KRGFTVIIDM RGSKWDLIKP LLKTLQEAFP 
AEIHVALIIK PDNFWQKQKT NFGSSKFIFE TSMVSVEGLT KLVDPSQLTE EFDGSLDYNH 
EEWIELRLSL EEFFNSAVHL LSRLEDLQEM LARKEFPVDV EGSRRLIDEH TQLKKKVLKA 
PVEELDREGQ RLLQCIRCSD GFSGRNCIPG SADFQSLVPK ITSLLDKLHS TRQHLHQMWH 
VRKLKLDQCF QLRLFEQDAE KMFDWISHNK ELFLQSHTEI GVSYQYALDL QTQHNHFAMN 
SMNAYVNINR IMSVASRLSE AGHYASQQIK QISTQLDQEW KSFAAALDER STILAMSAVF 
HQKAEQFLSG VDAWCKMCSE GGLPSEMQDL ELAIHHHQTL YEQVTQAYTE VSQDGKALLD 
VLQRPLSPGN SESLTATANY SKAVHQVLDV VHEVLHHQRR LESIWQHRKV RLHQRLQLCV 
FQQDVQQVLD WIENHGEAFL SKHTGVGKSL HRARALQKRH DDFEEVAQNT YTNADKLLEA 
AEQLAQTGEC DPEEIYKAAR HLEVRIQDFV RRVEQRKLLL DMSVSFHTHT KELWTWMEDL 
QKEMLEDVCA DSVDAVQELI KQFQQQQTAT LDATLNVIKE GEDLIQQLRS APPSLGEPSE 
ARDSAVSNNK TPHSSSISHI ESVLQQLDDA QVQMEELFHE RKIKLDIFLQ LRIFEQYTIE 
VTAELDAWNE DLLRQMNDFN TEDLTLAEQR LQRHTERKLA MNNMTFEVIQ QGQDLHQYIT 
EVQASGIELI CEKDIDLAAQ VQELLEFLHE KQHELELNAE QTHKRLEQCL QLRHLQAEVK 
QVLGWIRNGE SMLNASLVNA SSLSEAEQLQ REHEQFQLAI EKTHQSALQV QQKAEVLLQA 
GHYDADAIRE CAEKVALHWQ QLMLKMEDRL KLVNASVAFY KTSEQVCSVL ESLEQEYRRD 
EDWCGGRDKL GPAAEIDHVI PLISKHLEQK EAFLKACTLA RRNAEVFLKY IHRNNVSMPS 
VASHTRGPEQ QVKAILSELL QRENRVLHFW TLKKRRLDQC QQYVVFERSA KQALDWIQET 
GEFYLSTHTS TGETTEETQE LLKEYGEFRV PAKQTKEKVK LLIQLADSFV EKGHIHATEI 
RKWVTTVDKH YRDFSLRMGK YRYSLEKALG VNTEDNKDLE LDIIPASLSD REVKLRDANH 
EVNEEKRKSA RKKEFIMAEL LQTEKAYVRD LHECLETYLW EMTSGVEEIP PGILNKEHII 
FGNIQEIYDF HNNIFLKELE KYEQLPEDVG HCFVTWADKF QMYVTYCKNK PDSNQLILEH 
AGTFFDEIQQ RHGLANSISS YLIKPVQRIT KYQLLLKELL TCCEEGKGEL KDGLEVMLSV 
PKKANDAMHV SMLEGFDENL DVQGELILQD AFQVWDPKSL IRKGRERHLF LFEISLVFSK 
EIKDSSGHTK YVYKNKLLTS ELGVTEHVEG DPCKFALWSG RTPSSDNKTV LKASNIETKQ 
EWIKNIREVI QERIIHLKGA LKEPLQLPKT PAKQRNNSKR DGVEDIDSQG DGSSQPDTIS 
IASRTSQNTV DSDKDGNLVP RWHLGPGDPF STYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.