FYN | ENSG00000010810 | NCBI 2534

Details for: FYN

Gene ID: 2534

Symbol: FYN

Ensembl ID: ENSG00000010810

Description: FYN proto-oncogene, Src family tyrosine kinase

Associated with

Activated ntrk2 signals through fyn
(R-HSA-9032500)
Adaptive immune system
(R-HSA-1280218)
Anti-inflammatory response favouring leishmania parasite infection
(R-HSA-9662851)
Antigen activates b cell receptor (bcr) leading to generation of second messengers
(R-HSA-983695)
Axon guidance
(R-HSA-422475)
C-type lectin receptors (clrs)
(R-HSA-5621481)
Cd28 co-stimulation
(R-HSA-389356)
Cd28 dependent pi3k/akt signaling
(R-HSA-389357)
Cd28 dependent vav1 pathway
(R-HSA-389359)
Cd209 (dc-sign) signaling
(R-HSA-5621575)
Cell-cell communication
(R-HSA-1500931)
Cell surface interactions at the vascular wall
(R-HSA-202733)
Constitutive signaling by aberrant pi3k in cancer
(R-HSA-2219530)
Costimulation by the cd28 family
(R-HSA-388841)
Crmps in sema3a signaling
(R-HSA-399956)
Ctla4 inhibitory signaling
(R-HSA-389513)
Cytokine signaling in immune system
(R-HSA-1280215)
Dap12 interactions
(R-HSA-2172127)
Dap12 signaling
(R-HSA-2424491)
Dcc mediated attractive signaling
(R-HSA-418885)
Dectin-2 family
(R-HSA-5621480)
Developmental biology
(R-HSA-1266738)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Eph-ephrin mediated repulsion of cells
(R-HSA-3928665)
Eph-ephrin signaling
(R-HSA-2682334)
Epha-mediated growth cone collapse
(R-HSA-3928663)
Ephb-mediated forward signaling
(R-HSA-3928662)
Ephrin signaling
(R-HSA-3928664)
Fc epsilon receptor (fceri) signaling
(R-HSA-2454202)
Fcgamma receptor (fcgr) dependent phagocytosis
(R-HSA-2029480)
Fcgr3a-mediated il10 synthesis
(R-HSA-9664323)
Fcgr3a-mediated phagocytosis
(R-HSA-9664422)
Fcgr activation
(R-HSA-2029481)
Flt3 signaling
(R-HSA-9607240)
Flt3 signaling through src family kinases
(R-HSA-9706374)
Gpvi-mediated activation cascade
(R-HSA-114604)
Hemostasis
(R-HSA-109582)
Hiv infection
(R-HSA-162906)
Host interactions of hiv factors
(R-HSA-162909)
Immune system
(R-HSA-168256)
Infectious disease
(R-HSA-5663205)
Innate immune system
(R-HSA-168249)
Interleukin-3, interleukin-5 and gm-csf signaling
(R-HSA-512988)
Intracellular signaling by second messengers
(R-HSA-9006925)
Leishmania infection
(R-HSA-9658195)
Leishmania parasite growth and survival
(R-HSA-9664433)
Leishmania phagocytosis
(R-HSA-9664417)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Ncam signaling for neurite out-growth
(R-HSA-375165)
Nef and signal transduction
(R-HSA-164944)
Negative regulation of the pi3k/akt network
(R-HSA-199418)
Nephrin family interactions
(R-HSA-373753)
Nervous system development
(R-HSA-9675108)
Netrin-1 signaling
(R-HSA-373752)
Ntrk2 activates rac1
(R-HSA-9032759)
Parasite infection
(R-HSA-9664407)
Parasitic infection pathways
(R-HSA-9824443)
Pecam1 interactions
(R-HSA-210990)
Pi3k/akt signaling in cancer
(R-HSA-2219528)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-HSA-6811558)
Pip3 activates akt signaling
(R-HSA-1257604)
Platelet activation, signaling and aggregation
(R-HSA-76002)
Platelet adhesion to exposed collagen
(R-HSA-75892)
Raf/map kinase cascade
(R-HSA-5673001)
Reelin signalling pathway
(R-HSA-8866376)
Regulation of kit signaling
(R-HSA-1433559)
Regulation of signaling by cbl
(R-HSA-912631)
Role of lat2/ntal/lab on calcium mobilization
(R-HSA-2730905)
Sema3a-plexin repulsion signaling by inhibiting integrin adhesion
(R-HSA-399955)
Sema3a pak dependent axon repulsion
(R-HSA-399954)
Semaphorin interactions
(R-HSA-373755)
Signaling by csf1 (m-csf) in myeloid cells
(R-HSA-9680350)
Signaling by erbb2
(R-HSA-1227986)
Signaling by interleukins
(R-HSA-449147)
Signaling by kit in disease
(R-HSA-9669938)
Signaling by ntrk2 (trkb)
(R-HSA-9006115)
Signaling by ntrks
(R-HSA-166520)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain kit mutants
(R-HSA-9670439)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by scf-kit
(R-HSA-1433557)
Signaling by the b cell receptor (bcr)
(R-HSA-983705)
Signaling by vegf
(R-HSA-194138)
Signal transduction
(R-HSA-162582)
The role of nef in hiv-1 replication and disease pathogenesis
(R-HSA-164952)
Vegfa-vegfr2 pathway
(R-HSA-4420097)
Viral infection pathways
(R-HSA-9824446)
Atp binding
(GO:0005524)
Enzyme binding
(GO:0019899)
Non-membrane spanning protein tyrosine kinase activity
(GO:0004715)
Phospholipase activator activity
(GO:0016004)
Protein binding
(GO:0005515)
Protein tyrosine kinase activity
(GO:0004713)
Signaling receptor binding
(GO:0005102)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: Purkinje cell (CL0000121)
Fold Change: 4.81