Details for: DTNA
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 201.5631
Cell Significance Index: -95.1600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 30.9081
Cell Significance Index: -67.6500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 23.9075
Cell Significance Index: -94.3400 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 12.1436
Cell Significance Index: 169.8100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 7.3745
Cell Significance Index: 189.5600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 6.5506
Cell Significance Index: 502.6800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 5.8454
Cell Significance Index: 393.0500 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 5.2854
Cell Significance Index: 128.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 4.2448
Cell Significance Index: 1522.5200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 3.0583
Cell Significance Index: 52.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.8587
Cell Significance Index: 573.4500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 2.7614
Cell Significance Index: 44.5600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.6252
Cell Significance Index: 116.1200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.5655
Cell Significance Index: 97.1500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.4579
Cell Significance Index: 70.1400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.9649
Cell Significance Index: 204.5900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.9245
Cell Significance Index: 1331.0300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.9201
Cell Significance Index: 871.4800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.5835
Cell Significance Index: 19.6400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.4049
Cell Significance Index: 86.3500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.3862
Cell Significance Index: 2610.1000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 1.1280
Cell Significance Index: 63.3000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.0729
Cell Significance Index: 212.9200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.0165
Cell Significance Index: 645.5900 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 0.7307
Cell Significance Index: 8.1200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.7205
Cell Significance Index: 979.7300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.4626
Cell Significance Index: 6.8300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.4307
Cell Significance Index: 794.3900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.4186
Cell Significance Index: 10.0400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3909
Cell Significance Index: 601.7600 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.3465
Cell Significance Index: 5.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1514
Cell Significance Index: 7.1200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1331
Cell Significance Index: 22.7300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0564
Cell Significance Index: 8.2000 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0088
Cell Significance Index: -0.1100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: -0.0273
Cell Significance Index: -24.6500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0505
Cell Significance Index: -37.3800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0792
Cell Significance Index: -49.4800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1022
Cell Significance Index: -57.6500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.1140
Cell Significance Index: -83.5700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.1143
Cell Significance Index: -21.7600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1377
Cell Significance Index: -104.2200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.1643
Cell Significance Index: -89.7100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.2145
Cell Significance Index: -94.8500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2853
Cell Significance Index: -82.1000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3549
Cell Significance Index: -45.4900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3556
Cell Significance Index: -45.9400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3638
Cell Significance Index: -76.6300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.3809
Cell Significance Index: -68.6600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4092
Cell Significance Index: -13.1100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.4517
Cell Significance Index: -73.4700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5079
Cell Significance Index: -10.7800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.5562
Cell Significance Index: -7.0200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.6221
Cell Significance Index: -85.4300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.6251
Cell Significance Index: -63.8500 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.6264
Cell Significance Index: -10.8300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.6370
Cell Significance Index: -78.3200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.6617
Cell Significance Index: -75.8100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.6828
Cell Significance Index: -74.2700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.6899
Cell Significance Index: -51.4200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.7196
Cell Significance Index: -82.1400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.7548
Cell Significance Index: -87.9600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.7732
Cell Significance Index: -76.4900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7964
Cell Significance Index: -41.8200 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.8035
Cell Significance Index: -10.4200 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.9262
Cell Significance Index: -10.6000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -1.0185
Cell Significance Index: -14.5900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.0308
Cell Significance Index: -22.5700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.0449
Cell Significance Index: -20.6600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.0902
Cell Significance Index: -86.3400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -1.2029
Cell Significance Index: -15.4300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.2413
Cell Significance Index: -85.8500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.2422
Cell Significance Index: -76.1600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -1.2633
Cell Significance Index: -75.8400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -1.3308
Cell Significance Index: -62.0500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -1.3862
Cell Significance Index: -89.4300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.3972
Cell Significance Index: -44.5000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -1.4106
Cell Significance Index: -63.9400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -1.4713
Cell Significance Index: -51.7000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.4802
Cell Significance Index: -77.1000 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -1.4851
Cell Significance Index: -15.4700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.6525
Cell Significance Index: -104.1600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.6765
Cell Significance Index: -54.8900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.7005
Cell Significance Index: -34.1400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.7159
Cell Significance Index: -89.1400 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -1.7929
Cell Significance Index: -14.6200 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -1.8442
Cell Significance Index: -26.5300 - Cell Name: neural cell (CL0002319)
Fold Change: -1.9612
Cell Significance Index: -22.8800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.9619
Cell Significance Index: -68.7300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -2.0700
Cell Significance Index: -59.6400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -2.0738
Cell Significance Index: -51.7300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -2.1033
Cell Significance Index: -52.4500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -2.1965
Cell Significance Index: -69.4700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -2.1969
Cell Significance Index: -76.3400 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -2.1988
Cell Significance Index: -23.9600 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -2.3698
Cell Significance Index: -49.4600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -2.4479
Cell Significance Index: -50.7800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -2.4915
Cell Significance Index: -53.8300 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -2.5051
Cell Significance Index: -60.6800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -2.5254
Cell Significance Index: -37.2800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2841911316
Symbol: DTNA_HUMAN
Name: Alpha-dystrobrevin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8845841
Title: Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post-synaptic membrane.
PubMed ID: 8845841
DOI: 10.1093/hmg/5.4.489
PubMed ID: 10735273
Title: The genomic organization of human dystrobrevin.
PubMed ID: 10735273
PubMed ID: 9701558
Title: Characterisation of alpha-dystrobrevin in muscle.
PubMed ID: 9701558
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16177791
Title: DNA sequence and analysis of human chromosome 18.
PubMed ID: 16177791
DOI: 10.1038/nature03983
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7844150
Title: Syntrophin binds to an alternatively spliced exon of dystrophin.
PubMed ID: 7844150
PubMed ID: 8576247
Title: The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives.
PubMed ID: 8576247
PubMed ID: 10747910
Title: Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.
PubMed ID: 10747910
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 11238270
Title: Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome.
PubMed ID: 11238270
Sequence Information:
- Length: 743
- Mass: 83901
- Checksum: CFD77DAA57D050EC
- Sequence:
MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE ALRENALNNL DPNTELNVSR LEAVLSTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSG VMVYGRYDQF LREVLKLPTA VFEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP FITRSSPPKD SEVEQNKLLA RAAPAFLKGK GIQYSLNVAD RLADEHVLIG LYVNMLRNNP SCMLESSNRL DEEHRLIARY AARLAAESSS SQPPQQRSAP DISFTIDANK QQRQLIAELE NKNREILQEI QRLRLEHEQA SQPTPEKAQQ NPTLLAELRL LRQRKDELEQ RMSALQESRR ELMVQLEGLM KLLKTQGAGS PRSSPSHTIS RPIPMPIRSA SACSTPTHTP QDSLTGVGGD VQEAFAQSSR RNLRNDLLVA ADSITNTMSS LVKELNSEVG SETESNVDSE FARTQFEDLV PSPTSEKAFL AQIHARKPGY IHSGATTSTM RGDMVTEDAD PYVQPEDENY ENDSVRQLEN ELQMEEYLKQ KLQDEAYQVS LQG
Genular Protein ID: 615000775
Symbol: B7Z3X3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 433
- Mass: 48743
- Checksum: 7C358E442520AD5B
- Sequence:
MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVPPRPVT SMNDTLFSHS VPSSGSPFIT RSMLESSNRL DEEHRLIARY AARLAAESSS SQPPQQRSAP DISFTIDANK QQRQLIAELE NKNREILQEI QRLRLEHEQA SQPTPEKAQQ NPTLLAELRL LRQRKDELEQ RMSALQESRR ELMVQLEGLM KLLKTQGAGS PRSSPSHTIS RPIPMPIRSA SACSTPTHTP QDSLTGVGGD VQEAFAQSSR RNLRNDLLVA ADSITNTMSS LVKELNSEVG SETESNVDSE FARTQFEDLV PSPTSEKAFL AQIHARKPGY IHSGATTSTM RGDMVTEDAD PYVQPEDENY ENDSVRQLEN ELQMEEYLKQ KLQDEAYQVS LQG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.