Details for: ESRRG
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 74.3551
Cell Significance Index: -70.9900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 9.1232
Cell Significance Index: 1326.1700 - Cell Name: epithelial cell of sweat gland (CL1000448)
Fold Change: 6.1288
Cell Significance Index: 4.3800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 5.6807
Cell Significance Index: 435.9300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 3.8371
Cell Significance Index: 215.3200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 3.1466
Cell Significance Index: 198.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.4590
Cell Significance Index: 493.2700 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 2.4057
Cell Significance Index: 25.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.2606
Cell Significance Index: 810.8300 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 2.2369
Cell Significance Index: 54.5800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.1930
Cell Significance Index: 97.0000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.9377
Cell Significance Index: 368.7500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.8963
Cell Significance Index: 1311.5600 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 1.4753
Cell Significance Index: 20.6300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.3360
Cell Significance Index: 50.5900 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.3074
Cell Significance Index: 19.8900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.3014
Cell Significance Index: 34.7500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 1.2030
Cell Significance Index: 17.7600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.0111
Cell Significance Index: 642.1700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.0049
Cell Significance Index: 1892.0500 - Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
Fold Change: 0.8624
Cell Significance Index: 8.6300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.8227
Cell Significance Index: 23.7100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.7693
Cell Significance Index: 40.3900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6483
Cell Significance Index: 39.8500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.6190
Cell Significance Index: 1141.6000 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.5076
Cell Significance Index: 6.3300 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.5058
Cell Significance Index: 6.0300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5012
Cell Significance Index: 452.5800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.4587
Cell Significance Index: 13.0900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.3538
Cell Significance Index: 544.5900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.3278
Cell Significance Index: 22.0400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.2478
Cell Significance Index: 336.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2219
Cell Significance Index: 21.9600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1232
Cell Significance Index: 20.0300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1202
Cell Significance Index: 2.0600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0593
Cell Significance Index: 43.4600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0334
Cell Significance Index: -20.8500 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0374
Cell Significance Index: -20.4300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0463
Cell Significance Index: -34.2700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0481
Cell Significance Index: -1.6900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0560
Cell Significance Index: -10.1000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0620
Cell Significance Index: -6.7500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1093
Cell Significance Index: -49.5900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1123
Cell Significance Index: -63.3600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1242
Cell Significance Index: -94.0400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1360
Cell Significance Index: -2.0500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.1366
Cell Significance Index: -60.3800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1536
Cell Significance Index: -6.6800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1940
Cell Significance Index: -33.1200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2156
Cell Significance Index: -5.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2398
Cell Significance Index: -69.0100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2890
Cell Significance Index: -60.8700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2972
Cell Significance Index: -13.4700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.3206
Cell Significance Index: -19.2500 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.3292
Cell Significance Index: -4.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.3719
Cell Significance Index: -73.8100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3846
Cell Significance Index: -44.0600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.4584
Cell Significance Index: -47.7300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.4624
Cell Significance Index: -31.9800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.4650
Cell Significance Index: -57.1700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.5057
Cell Significance Index: -64.8300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.5355
Cell Significance Index: -73.5400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5423
Cell Significance Index: -11.5100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.5737
Cell Significance Index: -58.6100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.5883
Cell Significance Index: -76.0000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.6275
Cell Significance Index: -13.6000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.6683
Cell Significance Index: -9.5700 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.6866
Cell Significance Index: -80.0200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.6985
Cell Significance Index: -14.4900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.7177
Cell Significance Index: -84.6400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7350
Cell Significance Index: -45.0600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.7691
Cell Significance Index: -87.7900 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.8079
Cell Significance Index: -10.3600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.8211
Cell Significance Index: -65.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.9532
Cell Significance Index: -44.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.9736
Cell Significance Index: -68.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -1.0160
Cell Significance Index: -75.7200 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.0344
Cell Significance Index: -22.6500 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -1.0795
Cell Significance Index: -14.4000 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -1.1052
Cell Significance Index: -19.1100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.1508
Cell Significance Index: -36.8600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.1658
Cell Significance Index: -60.5600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.1881
Cell Significance Index: -38.9000 - Cell Name: neural cell (CL0002319)
Fold Change: -1.2078
Cell Significance Index: -14.0900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.2754
Cell Significance Index: -40.6200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -1.3087
Cell Significance Index: -84.4300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3126
Cell Significance Index: -33.7400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -1.3238
Cell Significance Index: -16.4200 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -1.3282
Cell Significance Index: -14.4700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -1.3328
Cell Significance Index: -62.1400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.3627
Cell Significance Index: -70.9800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.3736
Cell Significance Index: -27.1600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.4166
Cell Significance Index: -49.6300 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: -1.4636
Cell Significance Index: -13.1900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.4642
Cell Significance Index: -40.9200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.5421
Cell Significance Index: -30.9600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -1.6445
Cell Significance Index: -35.5300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -1.7138
Cell Significance Index: -42.7500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.7350
Cell Significance Index: -43.3700 - Cell Name: neuron (CL0000540)
Fold Change: -1.7412
Cell Significance Index: -16.5100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1008709397
Symbol: ERR3_HUMAN
Name: Estrogen-related receptor gamma
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10072763
Title: Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.
PubMed ID: 10072763
PubMed ID: 10048485
Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10048485
PubMed ID: 9676434
Title: Isolation of a gene encoding a novel member of the nuclear receptor superfamily from the critical region of Usher syndrome type IIa at 1q41.
PubMed ID: 9676434
PubMed ID: 10707956
Title: Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult.
PubMed ID: 10707956
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10428842
Title: Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3.
PubMed ID: 10428842
PubMed ID: 14651967
Title: Identification of PNRC2 and TLE1 as activation function-1 cofactors of the orphan nuclear receptor ERRgamma.
PubMed ID: 14651967
PubMed ID: 16371476
Title: PDSM, a motif for phosphorylation-dependent SUMO modification.
PubMed ID: 16371476
PubMed ID: 19067653
Title: Transcriptional ERRgamma2-mediated activation is regulated by sentrin-specific proteases.
PubMed ID: 19067653
DOI: 10.1042/bj20081556
PubMed ID: 18063693
Title: Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif.
PubMed ID: 18063693
DOI: 10.1210/me.2007-0357
PubMed ID: 20484414
Title: An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha.
PubMed ID: 20484414
DOI: 10.1210/me.2009-0441
PubMed ID: 23836911
Title: Peroxisome proliferator-activated receptor gamma coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.
PubMed ID: 23836911
PubMed ID: 11864604
Title: Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3.
PubMed ID: 11864604
PubMed ID: 16307879
Title: Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma.
PubMed ID: 16307879
PubMed ID: 16990259
Title: X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.
PubMed ID: 16990259
Sequence Information:
- Length: 458
- Mass: 51306
- Checksum: 63D36CFD37573152
- Sequence:
MDSVELCLPE SFSLHYEEEL LCRMSNKDRH IDSSCSSFIK TEPSSPASLT DSVNHHSPGG SSDASGSYSS TMNGHQNGLD SPPLYPSAPI LGGSGPVRKL YDDCSSTIVE DPQTKCEYML NSMPKRLCLV CGDIASGYHY GVASCEACKA FFKRTIQGNI EYSCPATNEC EITKRRRKSC QACRFMKCLK VGMLKEGVRL DRVRGGRQKY KRRIDAENSP YLNPQLVQPA KKPYNKIVSH LLVAEPEKIY AMPDPTVPDS DIKALTTLCD LADRELVVII GWAKHIPGFS TLSLADQMSL LQSAWMEILI LGVVYRSLSF EDELVYADDY IMDEDQSKLA GLLDLNNAIL QLVKKYKSMK LEKEEFVTLK AIALANSDSM HIEDVEAVQK LQDVLHEALQ DYEAGQHMED PRRAGKMLMT LPLLRQTSTK AVQHFYNIKL EGKVPMHKLF LEMLEAKV
Genular Protein ID: 1905117442
Symbol: C0SQ93_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 19304792
Title: Placenta expressing the greatest quantity of bisphenol A receptor ERR{gamma} among the human reproductive tissues: Predominant expression of type-1 ERRgamma isoform.
PubMed ID: 19304792
DOI: 10.1093/jb/mvp049
Sequence Information:
- Length: 435
- Mass: 48553
- Checksum: C9AEB9BB20A5F211
- Sequence:
MSNKDRHIDS SCSSFIKTEP SSPASLTDSV NHHSPGGSSD ASGSYSSTMN GHQNGLDSPP LYPSAPILGG SGPVRKLYDD CSSTIVEDPQ TKCEYMLNSM PKRLCLVCGD IASGYHYGVA SCEACKAFFK RTIQGNIEYS CPATNECEIT KRRRKSCQAC RFMKCLKVGM LKEGVRLDRV RGGRQKYKRR IDAENSPYLN PQLAQPAKKP YNKIVSHLLV AEPEKIYAMP DPTVPDSDIK ALTTLCDLAD RELVVIIGWA KHIPGFSTLS LADQMSLLQS AWMEILILGV VYRSLSFEDE LVYADDYIMD EDQSKLAGLL DLNNAILQLV KKYKSMKLEK EEFVTLKAIA LANSDSMHIE DVEAVQKLQD VLHEALQDYE AGQHMEDPRR AGKMLMTLPL LRQTSTKAVQ HFYNIKLEGK VPMHKLFLEM LEAKV
Genular Protein ID: 119198876
Symbol: F1D8R6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 435
- Mass: 48581
- Checksum: 63F81CDBE3A9C2D5
- Sequence:
MSNKDRHIDS SCSSFIKTEP SSPASLTDSV NHHSPGGSSD ASGSYSSTMN GHQNGLDSPP LYPSAPILGG SGPVRKLYDD CSSTIVEDPQ TKCEYMLNSM PKRLCLVCGD IASGYHYGVA SCEACKAFFK RTIQGNIEYS CPATNECEIT KRRRKSCQAC RFMKCLKVGM LKEGVRLDRV RGGRQKYKRR IDAENSPYLN PQLVQPAKKP YNKIVSHLLV AEPEKIYAMP DPTVPDSDIK ALTTLCDLAD RELVVIIGWA KHIPGFSTLS LADQMSLLQS AWMEILILGV VYRSLSFEDE LVYADDYIMD EDQSKLAGLL DLNNAILQLV KKYKSMKLEK EEFVTLKAIA LANSDSMHIE DVEAVQKLQD VLHEALQDYE AGQHMEDPRR AGKMLMTLPL LRQTSTKAVQ HFYNIKLEGK VPMHKLFLEM LEAKV
Genular Protein ID: 634123852
Symbol: B7Z5E9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 273
- Mass: 31079
- Checksum: 3C3F278AFDE6545C
- Sequence:
MKCLKVGMLK EGVRLDRVRG GRQKYKRRID AENSPYLNPQ LVQPAKKPYN KIVSHLLVAE PEKIYAMPDP TVPDSDIKAL TTLCDLADRE LVVIIGWAKH IPGFSTLSLA DQMSLLQSAW MEILILGVVY RSLSFEDELV YADDYIMDED QSKLAGLLDL NNAILQLVKK YKSMKLEKEE FVTLKAIALA NSDSMHIEDV EAVQKLQDVL HEALQDYEAG QHMEDPRRAG KMLMTLPLLR QTSTKAVQHF YNIKLEGKVP MHKLFLEMLE AKV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.