Details for: DPP6

Gene ID: 1804

Symbol: DPP6

Ensembl ID: ENSG00000130226

Description: dipeptidyl peptidase like 6

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 902.0528
    Cell Significance Index: -140.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 559.8806
    Cell Significance Index: -142.0100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.0267
    Cell Significance Index: -28.5100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 6.6860
    Cell Significance Index: 2398.1500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 6.5438
    Cell Significance Index: 289.4500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.3368
    Cell Significance Index: 239.9600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.1520
    Cell Significance Index: 346.4200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.9375
    Cell Significance Index: 140.9000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 4.3219
    Cell Significance Index: 74.0700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.9627
    Cell Significance Index: 2740.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.7241
    Cell Significance Index: 228.9000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.6135
    Cell Significance Index: 86.6600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 3.5404
    Cell Significance Index: 36.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.3396
    Cell Significance Index: 669.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 2.1720
    Cell Significance Index: 315.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.1317
    Cell Significance Index: 2130.8100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.7727
    Cell Significance Index: 43.3600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5001
    Cell Significance Index: 317.6200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.4499
    Cell Significance Index: 5.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2451
    Cell Significance Index: 48.6500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1810
    Cell Significance Index: 163.4400
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: 0.1202
    Cell Significance Index: 1.6900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0794
    Cell Significance Index: 2.2200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.0108
    Cell Significance Index: 0.1400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0212
    Cell Significance Index: -32.6500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0225
    Cell Significance Index: -41.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0235
    Cell Significance Index: -14.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0273
    Cell Significance Index: -20.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0507
    Cell Significance Index: -68.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0982
    Cell Significance Index: -55.3700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1416
    Cell Significance Index: -26.9500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1501
    Cell Significance Index: -110.0600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1606
    Cell Significance Index: -72.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1770
    Cell Significance Index: -133.9900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1771
    Cell Significance Index: -1.9300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1953
    Cell Significance Index: -106.6800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.2509
    Cell Significance Index: -110.9300
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2876
    Cell Significance Index: -3.6300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3195
    Cell Significance Index: -67.2900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3264
    Cell Significance Index: -93.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3560
    Cell Significance Index: -18.6900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3825
    Cell Significance Index: -68.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.4062
    Cell Significance Index: -66.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4071
    Cell Significance Index: -55.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4112
    Cell Significance Index: -25.2100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4511
    Cell Significance Index: -8.9200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5206
    Cell Significance Index: -11.4000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.5402
    Cell Significance Index: -92.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5565
    Cell Significance Index: -7.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.6717
    Cell Significance Index: -66.4500
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.6722
    Cell Significance Index: -9.4000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.6865
    Cell Significance Index: -24.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.7405
    Cell Significance Index: -91.0500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.8547
    Cell Significance Index: -110.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.8549
    Cell Significance Index: -109.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.9437
    Cell Significance Index: -102.6500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.9454
    Cell Significance Index: -98.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.0195
    Cell Significance Index: -104.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.0629
    Cell Significance Index: -121.7700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.0728
    Cell Significance Index: -122.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.0877
    Cell Significance Index: -126.7600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.1246
    Cell Significance Index: -13.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.1515
    Cell Significance Index: -24.4400
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -1.1593
    Cell Significance Index: -11.0300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.3012
    Cell Significance Index: -16.4200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.3478
    Cell Significance Index: -93.2100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -1.3741
    Cell Significance Index: -18.3300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.4040
    Cell Significance Index: -107.7400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -1.4829
    Cell Significance Index: -67.2200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.4838
    Cell Significance Index: -110.5900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.5740
    Cell Significance Index: -45.3500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.6891
    Cell Significance Index: -20.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.7431
    Cell Significance Index: -57.0700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.7630
    Cell Significance Index: -38.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.8550
    Cell Significance Index: -119.6800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.8758
    Cell Significance Index: -46.8900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.8897
    Cell Significance Index: -98.4300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.9197
    Cell Significance Index: -61.1400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.9264
    Cell Significance Index: -115.6500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.9612
    Cell Significance Index: -68.7100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.9839
    Cell Significance Index: -39.8300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -2.0928
    Cell Significance Index: -14.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -2.0942
    Cell Significance Index: -131.9900
  • Cell Name: neuron (CL0000540)
    Fold Change: -2.1626
    Cell Significance Index: -20.5000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -2.1708
    Cell Significance Index: -54.1500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.2362
    Cell Significance Index: -105.1000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -2.2778
    Cell Significance Index: -27.2400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -2.4482
    Cell Significance Index: -114.1500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -2.5011
    Cell Significance Index: -52.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -2.5195
    Cell Significance Index: -87.5500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.7091
    Cell Significance Index: -140.7300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -2.8944
    Cell Significance Index: -70.1100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -3.0650
    Cell Significance Index: -112.5200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -3.1344
    Cell Significance Index: -80.5700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -3.1772
    Cell Significance Index: -101.7600
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -3.3401
    Cell Significance Index: -27.5700
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -3.3970
    Cell Significance Index: -66.8600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -3.5278
    Cell Significance Index: -153.4000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -3.5506
    Cell Significance Index: -61.3900
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -3.7345
    Cell Significance Index: -74.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DPP6 exhibits the following characteristics: 1. **Serine-type peptidase activity**: DPP6 possesses serine-type peptidase activity, which involves the cleavage of peptide bonds using a serine residue. 2. **Dipeptidyl peptidase-like activity**: DPP6 shares similarities with dipeptidyl peptidases, which are enzymes that cleave dipeptides from the N-terminus of protein substrates. 3. **Plasma membrane localization**: DPP6 is primarily localized to the plasma membrane, where it regulates ion transport and signaling pathways. 4. **Regulation of potassium ion transmembrane transport**: DPP6 has been shown to regulate potassium ion transmembrane transport, which is essential for maintaining proper ion balance and neuronal function. 5. **Voltage-gated potassium channel complex formation**: DPP6 is involved in the formation of voltage-gated potassium channels, which are critical for neuronal excitability and signaling. **Pathways and Functions** DPP6 is involved in the following pathways and functions: 1. **Potassium ion transmembrane transport**: DPP6 regulates potassium ion transmembrane transport, which is essential for maintaining proper ion balance and neuronal function. 2. **Voltage-gated potassium channel complex formation**: DPP6 is involved in the formation of voltage-gated potassium channels, which are critical for neuronal excitability and signaling. 3. **Protein localization to plasma membrane**: DPP6 regulates protein localization to the plasma membrane, which is essential for maintaining proper cellular function. 4. **Regulation of dipeptidyl peptidase activity**: DPP6 may regulate dipeptidyl peptidase activity, which is involved in protein processing and degradation. 5. **Neuronal signaling and regulation**: DPP6 is involved in neuronal signaling and regulation, including the regulation of potassium ion transmembrane transport and voltage-gated potassium channel complex formation. **Clinical Significance** DPP6 has been implicated in various neurological and psychiatric disorders, including: 1. **Neurodegenerative diseases**: DPP6 has been linked to neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. **Neuropsychiatric disorders**: DPP6 has been implicated in neuropsychiatric disorders, such as schizophrenia, bipolar disorder, and depression. 3. **Neurological disorders**: DPP6 has been linked to neurological disorders, such as epilepsy, migraines, and multiple sclerosis. Further research is needed to fully understand the role of DPP6 in human disease and to explore its potential as a therapeutic target for neurological and psychiatric disorders.

Genular Protein ID: 1705717163

Symbol: DPP6_HUMAN

Name: DPPX

UniProtKB Accession Codes:

P42658

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 6 EMDB 6 ESTHER 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MEROPS 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8103397

Title: Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7.

PubMed ID: 8103397

DOI: 10.1093/hmg/2.7.1037

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15454437

Title: Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10).

PubMed ID: 15454437

DOI: 10.1529/biophysj.104.042358

PubMed ID: 18364354

Title: I SA channel complexes include four subunits each of DPP6 and Kv4.2.

PubMed ID: 18364354

DOI: 10.1074/jbc.m706964200

PubMed ID: 18084291

Title: Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.

PubMed ID: 18084291

DOI: 10.1038/ng.2007.52

PubMed ID: 18174402

Title: Genetics. The elusive ALS genes.

PubMed ID: 18174402

DOI: 10.1126/science.319.5859.20

PubMed ID: 19285295

Title: Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.

PubMed ID: 19285295

DOI: 10.1016/j.ajhg.2009.02.009

PubMed ID: 19441798

Title: Convergent modulation of Kv4.2 channel alpha subunits by structurally distinct DPPX and KChIP auxiliary subunits.

PubMed ID: 19441798

DOI: 10.1021/bi802316m

PubMed ID: 23832105

Title: Loss-of-function variation in the DPP6 gene is associated with autosomal dominant microcephaly and mental retardation.

PubMed ID: 23832105

DOI: 10.1016/j.ejmg.2013.06.008

PubMed ID: 15476821

Title: Structure of a human A-type potassium channel interacting protein DPPX, a member of the dipeptidyl aminopeptidase family.

PubMed ID: 15476821

DOI: 10.1016/j.jmb.2004.09.003

Sequence Information:

  • Length: 865
  • Mass: 97588
  • Checksum: D3E654013F19D951
  • Sequence:
    • MASLYQRFTG KINTSRSFPA PPEASHLLGG QGPEEDGGAG AKPLGPRAQA AAPRERGGGG 
GGAGGRPRFQ YQARSDGDEE DELVGSNPPQ RNWKGIAIAL LVILVICSLI VTSVILLTPA 
EDNSLSQKKK VTVEDLFSED FKIHDPEAKW ISDTEFIYRE QKGTVRLWNV ETNTSTVLIE 
GKKIESLRAI RYEISPDREY ALFSYNVEPI YQHSYTGYYV LSKIPHGDPQ SLDPPEVSNA 
KLQYAGWGPK GQQLIFIFEN NIYYCAHVGK QAIRVVSTGK EGVIYNGLSD WLYEEEILKT 
HIAHWWSPDG TRLAYAAIND SRVPIMELPT YTGSIYPTVK PYHYPKAGSE NPSISLHVIG 
LNGPTHDLEM MPPDDPRMRE YYITMVKWAT STKVAVTWLN RAQNVSILTL CDATTGVCTK 
KHEDESEAWL HRQNEEPVFS KDGRKFFFIR AIPQGGRGKF YHITVSSSQP NSSNDNIQSI 
TSGDWDVTKI LAYDEKGNKI YFLSTEDLPR RRQLYSANTV GNFNRQCLSC DLVENCTYFS 
ASFSHSMDFF LLKCEGPGVP MVTVHNTTDK KKMFDLETNE HVKKAINDRQ MPKVEYRDIE 
IDDYNLPMQI LKPATFTDTT HYPLLLVVDG TPGSQSVAEK FEVSWETVMV SSHGAVVVKC 
DGRGSGFQGT KLLHEVRRRL GLLEEKDQME AVRTMLKEQY IDRTRVAVFG KDYGGYLSTY 
ILPAKGENQG QTFTCGSALS PITDFKLYAS AFSERYLGLH GLDNRAYEMT KVAHRVSALE 
EQQFLIIHPT ADEKIHFQHT AELITQLIRG KANYSLQIYP DESHYFTSSS LKQHLYRSII 
NFFVECFRIQ DKLLTVTAKE DEEED

Genular Protein ID: 2505667111

Symbol: E9PDL2_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PDL2

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 ESTHER 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 MEROPS 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 758
  • Mass: 86327
  • Checksum: 0FCA84860AD946EA
  • Sequence:
    • MTTAKEPSAS GKSVQQQEQE LVGSNPPQRN WKGIAIALLV ILVICSLIVT SVILLTPAED 
NSLSQKKKVT VEDLFSEDFK IHDPEAKWIS DTEFIYREQK GTVRLWNVET NTSTVLIEGK 
KIESLRAIRY EISPDREYAL FSYNVEPIFI FENNIYYCAH VGKQAIRVVS TGKEGVIYNG 
LSDWLYEEEI LKTHIAHWWS PDGTRLAYAA INDSRVPIME LPTYTGSIYP TVKPYHYPKA 
GSENPSISLH VIGLNGPTHD LEMMPPDDPR MREYYITMVK WATSTKVAVT WLNRAQNVSI 
LTLCDATTGV CTKKHEDESE AWLHRQNEEP VFSKDGRKFF FIRAIPQGGR GKFYHITVSS 
SQPNSSNDNI QSITSGDWDV TKILAYDEKG NKIYFLSTED LPRRRQLYSA NTVGNFNRQC 
LSCDLVENCT YFSASFSHSM DFFLLKCEGP GVPMVTVHNT TDKKKMFDLE TNEHVKKAIN 
DRQMPKVEYR DIEIDDYNLP MQILKPATFT DTTHYPLLLV VDGTPGSQSV AEKFEVSWET 
VMVSSHGAVV VKCDGRGSGF QGTKLLHEVR RRLGLLEEKD QMEAVRTMLK EQYIDRTRVA 
VFGKDYGGYL STYILPAKGE NQGQTFTCGS ALSPITDFKL YASAFSERYL GLHGLDNRAY 
EMTKVAHRVS ALEEQQFLII HPTADEKIHF QHTAELITQL IRGKANYSLQ IYPDESHYFT 
SSSLKQHLYR SIINFFVECF RIQDKLLTVT AKEDEEED

Genular Protein ID: 2318865344

Symbol: E9PF59_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PF59

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 ESTHER 1 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 MEROPS 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 801
  • Mass: 91246
  • Checksum: 5B272181F6CD6391
  • Sequence:
    • MKEKAMIKTA KMQGNVMELV GSNPPQRNWK GIAIALLVIL VICSLIVTSV ILLTPAEDNS 
LSQKKKVTVE DLFSEDFKIH DPEAKWISDT EFIYREQKGT VRLWNVETNT STVLIEGKKI 
ESLRAIRYEI SPDREYALFS YNVEPIYQHS YTGYYVLSKI PHGDPQSLDP PEVSNAKLQY 
AGWGPKGQQL IFIFENNIYY CAHVGKQAIR VVSTGKEGVI YNGLSDWLYE EEILKTHIAH 
WWSPDGTRLA YAAINDSRVP IMELPTYTGS IYPTVKPYHY PKAGSENPSI SLHVIGLNGP 
THDLEMMPPD DPRMREYYIT MVKWATSTKV AVTWLNRAQN VSILTLCDAT TGVCTKKHED 
ESEAWLHRQN EEPVFSKDGR KFFFIRAIPQ GGRGKFYHIT VSSSQPNSSN DNIQSITSGD 
WDVTKILAYD EKGNKIYFLS TEDLPRRRQL YSANTVGNFN RQCLSCDLVE NCTYFSASFS 
HSMDFFLLKC EGPGVPMVTV HNTTDKKKMF DLETNEHVKK AINDRQMPKV EYRDIEIDDY 
NLPMQILKPA TFTDTTHYPL LLVVDGTPGS QSVAEKFEVS WETVMVSSHG AVVVKCDGRG 
SGFQGTKLLH EVRRRLGLLE EKDQMEAVRT MLKEQYIDRT RVAVFGKDYG GYLSTYILPA 
KGENQGQTFT CGSALSPITD FKLYASAFSE RYLGLHGLDN RAYEMTKVAH RVSALEEQQF 
LIIHPTADEK IHFQHTAELI TQLIRGKANY SLQIYPDESH YFTSSSLKQH LYRSIINFFV 
ECFRIQDKLL TVTAKEDEEE D

Genular Protein ID: 1818193701

Symbol: Q8IYG9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IYG9

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 353
  • Mass: 38695
  • Checksum: A57CFDD343CD54CE
  • Sequence:
    • MASLYQRFTG KINTSRSFPA PPEASHLLGG QGPEEDGGAG AKPLGPRAQA AAPRERGGGG 
GGAGGRPRFQ YQARSDGDEE DELVGSNPPQ RNWKGIAIAL LVILVICSLI VTSVILLTPA 
EDNSLSQKKK VTVEDLFSED FKIHDPEAKW ISDTEFIYRE QKGTVRLWNV ETNTSTVLIE 
GKKIESLRAI RYEISPDREY ALFSYNVEPM KKVKSRKLTL PHSKSCDSLA VSQACSPACH 
QGCFLHYITM SLPLHCLRDY VSAVNGYSTA LPACHVQGGP VSDIPWRPWL EDCRRVPGGR 
TANGTRLRSH APAALRQHCP LSYECGRCEA SHLLTPGIMH SSYRQISGQR ATE

Genular Protein ID: 1595480752

Symbol: A7E2E4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A7E2E4

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 EMDB 1 ESTHER 1 GO 5 Gene3D 2 InterPro 4 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 RefSeq 4 SAM 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 801
  • Mass: 91288
  • Checksum: AA00AAAF2EEC4BDF
  • Sequence:
    • MKEKAMIKTA KMQGNVMELV GSNPPQRNWK GIAIALLVIL VICSLIVTSV ILLTPAEDNS 
LSQKKKVTVE DLFSEDFKIH DPEAKWISDT EFIYREQKGT VRLWNVETNT STVLIEGKKI 
ESLRAIRYEI SPDREYALFS YNVEPIYQHS YTGYYVLSKI PHGDPQSLDP PEVSNAKLQY 
AGWGPKGQQL IFIFENNIYY CAHVGKQAIR VVSTGKEGVI YNGLSDWLYE EEILKTHIAH 
WWSPDGTRLA YAAINDSRVP IMELPTYTGS IYPTVKPYHY PKAGSENPSI SLHVIGLNGP 
THDLEMMPPD DPRMREYYIT MVKWATSTKV AVTWLNRAQN VSILTLCDAT TGVCTKKHED 
ESEAWLHRQN EEPVFSKDGR KFFFIRAIPQ GGRGKFYHIT VSSSQPNSSN DNIQSITSGD 
WDVTKILAYD EKGNKIYFLS TEDLPRRRQL YSANTVGNFN RQCLSCDLVE NCTYFSASFS 
HSMDFFLLKC EGPGVPMVTV HNTTDKKKMF DLETNEHVKK AINDRQMPKV EYRDIEIDDY 
NLPMQILKPA TFTDTTHYPL LLVVDGTPGS QSVAEKFEVS WETVMVSSHG AVVVKCEGRG 
SGFRGTKLLH EVRRRLGLLE EKDQMEAVRT MLKEQYIDRT RVAVFGKDYG GYLSTYILPA 
KGENQGQTFT CGSALSPITD FKLYASAFSE RYLGLHGLDN RAYEMTKVAH RVSALEEQQF 
LIIHPTADEK IHFQHTAELI TQLIRGKANY SLQIYPDESH YFTSSSLKQH LYRSIINFFV 
ECFRIQDKLL TVTAKEDEEE D

Genular Protein ID: 1090759594

Symbol: B7Z299_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z299

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ESTHER 1 GO 6 Gene3D 2 InterPro 4 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 2 SUPFAM 2

Sequence Information:

  • Length: 758
  • Mass: 86270
  • Checksum: B92BD310D9B86F5D
  • Sequence:
    • MTTAKEPSAS GKSVQQQEQE LVGSNPPQRN WKGIAIALLV ILVICSLIVT SVILLTPAED 
NSLSQKKKVT VEDLFSEDFK IHDPEAKWIS DTEFIYREQK GTVRLWNVET NTSTVLIEGK 
KIESLRAIRY EISPDREYAL FSYNVEPIFI FENNIYYCAH VGKQAIRVVS TGKEGVIYNG 
LSDWLYEEEI LKTHIAHWWS PGGTRLAYAA INDSRVPIME LPTYTGSIYP TVKPYHYPKA 
GSENPSISLH VIGLNGPTHD LEMMPPDDPR MREYYITMVE WATSTKVAVT WLNRAQNVSI 
LTLCDATTGV CTKKHEDESE AWLHRQNEEP VFSKDGRKFF FIRAIPQGGR GKFYHITVSS 
SQPNSSNDNI QSITSGDWDV TKILAYDEKG NKIYFLSTED LPRRRQLYSA NTVGNFNRQC 
LSCDLVENCT YFSASFSHSM DFFLLKCEGP GVPMVTVHNT TDKKKMFDLE TNEHVKKAIN 
DRQMPKVEYR DIEIDDYNLP MQILKPATFT DTTHYPLLLV VDGTPGSQSV AEKFEVSWET 
VMVSSHGAVV VKCDGRGSGF QGTKLLHEVR RRLGLLEEKD QMEAVRTMLK EQYIDRTRVA 
VFGKDYGGYL STYILPAKGE NQGQTFTCGS ALSPITDFKL YASAFSERYL GLHGLDNRAY 
EMTKVAHRVS ALEEQQFLII HPTADEKIHF QHTAELITQL IRGKANYSLQ IYPDESHYFT 
SSSLKQHLYR SIINFFVECF RIQDKLLTVT AKEDEEED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.