Details for: LRP2

Gene ID: 4036

Symbol: LRP2

Ensembl ID: ENSG00000081479

Description: LDL receptor related protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 57.5217
    Cell Significance Index: -14.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 6.5229
    Cell Significance Index: 174.1700
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 4.7747
    Cell Significance Index: 50.7300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 4.0698
    Cell Significance Index: 2584.7800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.2062
    Cell Significance Index: 4153.9700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.1960
    Cell Significance Index: 123.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.9949
    Cell Significance Index: 23.7800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.8273
    Cell Significance Index: 25.6700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.7208
    Cell Significance Index: 10.5900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.7178
    Cell Significance Index: 13.7200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.3207
    Cell Significance Index: 31.9900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.2173
    Cell Significance Index: 20.0600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.7319
    Cell Significance Index: 46.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2627
    Cell Significance Index: 19.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2446
    Cell Significance Index: 11.5000
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 0.1849
    Cell Significance Index: 2.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0736
    Cell Significance Index: 50.9100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0601
    Cell Significance Index: 7.7700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0594
    Cell Significance Index: 11.7900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0222
    Cell Significance Index: 34.1400
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.0217
    Cell Significance Index: 0.2800
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0170
    Cell Significance Index: 0.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0166
    Cell Significance Index: 2.4100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0132
    Cell Significance Index: 24.3700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0118
    Cell Significance Index: 8.9000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0087
    Cell Significance Index: 3.1300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0044
    Cell Significance Index: 0.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0031
    Cell Significance Index: 0.6300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.0009
    Cell Significance Index: 0.0700
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0069
    Cell Significance Index: -0.0600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0106
    Cell Significance Index: -5.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0117
    Cell Significance Index: -15.9300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0126
    Cell Significance Index: -9.2200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0154
    Cell Significance Index: -6.8200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0200
    Cell Significance Index: -14.8100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0214
    Cell Significance Index: -9.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0253
    Cell Significance Index: -14.2500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0260
    Cell Significance Index: -16.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0380
    Cell Significance Index: -10.9300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0412
    Cell Significance Index: -4.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0581
    Cell Significance Index: -2.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0637
    Cell Significance Index: -6.6300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0712
    Cell Significance Index: -12.1500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0725
    Cell Significance Index: -15.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0753
    Cell Significance Index: -13.5800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1059
    Cell Significance Index: -14.5400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1143
    Cell Significance Index: -14.0600
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1209
    Cell Significance Index: -1.5000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1213
    Cell Significance Index: -8.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1225
    Cell Significance Index: -14.2800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1385
    Cell Significance Index: -15.8700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1529
    Cell Significance Index: -2.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1605
    Cell Significance Index: -10.7900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1611
    Cell Significance Index: -19.0000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1681
    Cell Significance Index: -4.9500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2028
    Cell Significance Index: -8.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2065
    Cell Significance Index: -15.8500
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.2106
    Cell Significance Index: -1.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2154
    Cell Significance Index: -11.2200
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2220
    Cell Significance Index: -2.3800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2227
    Cell Significance Index: -13.6900
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.2409
    Cell Significance Index: -2.5000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2640
    Cell Significance Index: -10.8200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2840
    Cell Significance Index: -9.9500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3025
    Cell Significance Index: -15.8800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3104
    Cell Significance Index: -8.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3167
    Cell Significance Index: -16.0000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3178
    Cell Significance Index: -8.1700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3180
    Cell Significance Index: -5.4500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3202
    Cell Significance Index: -3.3200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3277
    Cell Significance Index: -5.0700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3303
    Cell Significance Index: -14.6100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3358
    Cell Significance Index: -15.2200
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: -0.3618
    Cell Significance Index: -3.0500
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: -0.3789
    Cell Significance Index: -4.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3882
    Cell Significance Index: -12.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3906
    Cell Significance Index: -14.7900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4082
    Cell Significance Index: -13.0000
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.4096
    Cell Significance Index: -4.4800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4116
    Cell Significance Index: -15.1100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4273
    Cell Significance Index: -14.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4345
    Cell Significance Index: -12.4000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4773
    Cell Significance Index: -16.7700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5122
    Cell Significance Index: -26.6100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5196
    Cell Significance Index: -14.9000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.5213
    Cell Significance Index: -13.0200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5264
    Cell Significance Index: -16.6500
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.5268
    Cell Significance Index: -7.8800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.5292
    Cell Significance Index: -13.2000
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.5369
    Cell Significance Index: -5.1400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5391
    Cell Significance Index: -14.4200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5420
    Cell Significance Index: -11.7100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.5481
    Cell Significance Index: -8.0900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5562
    Cell Significance Index: -16.3400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5625
    Cell Significance Index: -14.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.5685
    Cell Significance Index: -16.3800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5762
    Cell Significance Index: -15.4400
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.5784
    Cell Significance Index: -4.4500
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.5836
    Cell Significance Index: -7.7900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.5851
    Cell Significance Index: -11.9100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Multi-functional receptor**: LRP2 exhibits a wide range of functions, including cargo recognition, endocytosis, and transcytosis, making it a versatile receptor involved in various cellular processes. 2. **High expression levels**: LRP2 is highly expressed in multiple cell types, including those in the brain, kidney, and placenta, indicating its critical role in maintaining cellular homeostasis. 3. **Wide ligand specificity**: LRP2 recognizes and binds to a diverse array of ligands, including lipoproteins, hormones, and growth factors, highlighting its adaptability in responding to changing cellular environments. 4. **Regulation of cellular signaling pathways**: LRP2 modulates various signaling pathways, including the PI3K/Akt pathway, BMP signaling, and neurogenesis, underscoring its importance in regulating cellular behavior. **Pathways and Functions** 1. **Endocytosis and transcytosis**: LRP2 facilitates the uptake and processing of ligands through clathrin-coated endocytosis and transcytosis, contributing to cellular homeostasis and regulation of signaling pathways. 2. **Lipid metabolism**: LRP2 plays a critical role in lipid metabolism, including the uptake and degradation of lipoproteins, and the regulation of cholesterol homeostasis. 3. **Hormone regulation**: LRP2 modulates hormone signaling, including the regulation of leptin and insulin-like growth factor I (IGF-I) signaling pathways. 4. **Neurogenesis and neuronal development**: LRP2 is involved in the regulation of neurogenesis and neuronal development, influencing the formation and maintenance of neural tissue. 5. **Angiogenesis and vascular development**: LRP2 contributes to angiogenesis and vascular development, regulating the formation and function of blood vessels. **Clinical Significance** 1. **Dyslipidemia and cardiovascular disease**: Mutations in LRP2 have been associated with dyslipidemia and cardiovascular disease, highlighting the receptor's role in lipid metabolism and cardiovascular health. 2. **Neurodegenerative diseases**: LRP2's involvement in neurogenesis and neuronal development makes it a potential target for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. 3. **Cancer and metastasis**: Alterations in LRP2 expression and function have been linked to cancer progression and metastasis, suggesting its potential as a therapeutic target. 4. **Pregnancy and placental development**: LRP2 plays a critical role in placental development and function, underscoring its importance in reproductive health. In conclusion, LRP2 is a multifunctional receptor that plays a crucial role in maintaining cellular homeostasis, regulating cellular signaling pathways, and influencing various physiological processes. Its clinical significance extends to dyslipidemia, cardiovascular disease, neurodegenerative diseases, cancer, and pregnancy, highlighting the need for further research into the mechanisms of LRP2 function and its potential as a therapeutic target.

Genular Protein ID: 2340127315

Symbol: LRP2_HUMAN

Name: Low-density lipoprotein receptor-related protein 2

UniProtKB Accession Codes:

P98164 O00711 Q16215

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 11 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 59 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRINTS 1 PRO 1 PROSITE 8 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8706697

Title: Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties.

PubMed ID: 8706697

DOI: 10.1111/j.1432-1033.1996.0132u.x

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 7959795

Title: Chromosomal localization of human genes for the LDL receptor family member glycoprotein 330 (LRP2) and its associated protein RAP (LRPAP1).

PubMed ID: 7959795

DOI: 10.1006/geno.1994.1348

PubMed ID: 8187828

Title: A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belongs to the LDL-receptor protein superfamily.

PubMed ID: 8187828

DOI: 10.1006/excr.1994.1153

PubMed ID: 1400426

Title: The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.

PubMed ID: 1400426

DOI: 10.1016/s0021-9258(19)36811-5

PubMed ID: 7768901

Title: Identification of glycoprotein 330 as an endocytic receptor for apolipoprotein J/clusterin.

PubMed ID: 7768901

DOI: 10.1074/jbc.270.22.13070

PubMed ID: 10769163

Title: Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.

PubMed ID: 10769163

DOI: 10.1042/bj3470613

PubMed ID: 12508107

Title: Functional interaction of megalin with the megalin-binding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.

PubMed ID: 12508107

DOI: 10.1242/jcs.00243

PubMed ID: 15126248

Title: Megalin mediates renal uptake of heavy metal metallothionein complexes.

PubMed ID: 15126248

DOI: 10.1152/ajprenal.00233.2003

PubMed ID: 15134832

Title: The adaptor disabled-2 binds to the third psi xNPxY sequence on the cytoplasmic tail of megalin.

PubMed ID: 15134832

DOI: 10.1016/j.biochi.2004.03.001

PubMed ID: 16143106

Title: Role of endocytosis in cellular uptake of sex steroids.

PubMed ID: 16143106

DOI: 10.1016/j.cell.2005.06.032

PubMed ID: 17462596

Title: Megalin-mediated endocytosis of cystatin C in proximal tubule cells.

PubMed ID: 17462596

DOI: 10.1016/j.bbrc.2007.04.072

PubMed ID: 17324488

Title: Megalin mediates the transport of leptin across the blood-CSF barrier.

PubMed ID: 17324488

DOI: 10.1016/j.neurobiolaging.2007.01.008

PubMed ID: 23825075

Title: Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule.

PubMed ID: 23825075

DOI: 10.1152/ajprenal.00546.2012

PubMed ID: 27798286

Title: Megalin is predominantly observed in vesicular structures in first and third trimester cytotrophoblasts of the human placenta.

PubMed ID: 27798286

DOI: 10.1369/0022155416672210

PubMed ID: 23275343

Title: Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the NMR structure of the 10th complement type repeat domain alone and in complex with gentamicin.

PubMed ID: 23275343

DOI: 10.1074/jbc.m112.434159

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17632512

Title: Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes.

PubMed ID: 17632512

DOI: 10.1038/ng2063

PubMed ID: 21248752

Title: Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

PubMed ID: 21248752

DOI: 10.1038/nature09639

PubMed ID: 23992033

Title: Broadening the phenotype of LRP2 mutations: a new mutation in LRP2 causes a predominantly ocular phenotype suggestive of Stickler syndrome.

PubMed ID: 23992033

DOI: 10.1111/cge.12265

PubMed ID: 26529358

Title: Identification of a homozygous missense mutation in LRP2 and a hemizygous missense mutation in TSPYL2 in a family with mild intellectual disability.

PubMed ID: 26529358

DOI: 10.1097/ypg.0000000000000114

Sequence Information:

  • Length: 4655
  • Mass: 521958
  • Checksum: C73C4206B8B28CE0
  • Sequence:
    • MDRGPAAVAC TLLLALVACL APASGQECDS AHFRCGSGHC IPADWRCDGT KDCSDDADEI 
GCAVVTCQQG YFKCQSEGQC IPNSWVCDQD QDCDDGSDER QDCSQSTCSS HQITCSNGQC 
IPSEYRCDHV RDCPDGADEN DCQYPTCEQL TCDNGACYNT SQKCDWKVDC RDSSDEINCT 
EICLHNEFSC GNGECIPRAY VCDHDNDCQD GSDEHACNYP TCGGYQFTCP SGRCIYQNWV 
CDGEDDCKDN GDEDGCESGP HDVHKCSPRE WSCPESGRCI SIYKVCDGIL DCPGREDENN 
TSTGKYCSMT LCSALNCQYQ CHETPYGGAC FCPPGYIINH NDSRTCVEFD DCQIWGICDQ 
KCESRPGRHL CHCEEGYILE RGQYCKANDS FGEASIIFSN GRDLLIGDIH GRSFRILVES 
QNRGVAVGVA FHYHLQRVFW TDTVQNKVFS VDINGLNIQE VLNVSVETPE NLAVDWVNNK 
IYLVETKVNR IDMVNLDGSY RVTLITENLG HPRGIAVDPT VGYLFFSDWE SLSGEPKLER 
AFMDGSNRKD LVKTKLGWPA GVTLDMISKR VYWVDSRFDY IETVTYDGIQ RKTVVHGGSL 
IPHPFGVSLF EGQVFFTDWT KMAVLKANKF TETNPQVYYQ ASLRPYGVTV YHSLRQPYAT 
NPCKDNNGGC EQVCVLSHRT DNDGLGFRCK CTFGFQLDTD ERHCIAVQNF LIFSSQVAIR 
GIPFTLSTQE DVMVPVSGNP SFFVGIDFDA QDSTIFFSDM SKHMIFKQKI DGTGREILAA 
NRVENVESLA FDWISKNLYW TDSHYKSISV MRLADKTRRT VVQYLNNPRS VVVHPFAGYL 
FFTDWFRPAK IMRAWSDGSH LLPVINTTLG WPNGLAIDWA ASRLYWVDAY FDKIEHSTFD 
GLDRRRLGHI EQMTHPFGLA IFGEHLFFTD WRLGAIIRVR KADGGEMTVI RSGIAYILHL 
KSYDVNIQTG SNACNQPTHP NGDCSHFCFP VPNFQRVCGC PYGMRLASNH LTCEGDPTNE 
PPTEQCGLFS FPCKNGRCVP NYYLCDGVDD CHDNSDEQLC GTLNNTCSSS AFTCGHGECI 
PAHWRCDKRN DCVDGSDEHN CPTHAPASCL DTQYTCDNHQ CISKNWVCDT DNDCGDGSDE 
KNCNSTETCQ PSQFNCPNHR CIDLSFVCDG DKDCVDGSDE VGCVLNCTAS QFKCASGDKC 
IGVTNRCDGV FDCSDNSDEA GCPTRPPGMC HSDEFQCQED GICIPNFWEC DGHPDCLYGS 
DEHNACVPKT CPSSYFHCDN GNCIHRAWLC DRDNDCGDMS DEKDCPTQPF RCPSWQWQCL 
GHNICVNLSV VCDGIFDCPN GTDESPLCNG NSCSDFNGGC THECVQEPFG AKCLCPLGFL 
LANDSKTCED IDECDILGSC SQHCYNMRGS FRCSCDTGYM LESDGRTCKV TASESLLLLV 
ASQNKIIADS VTSQVHNIYS LVENGSYIVA VDFDSISGRI FWSDATQGKT WSAFQNGTDR 
RVVFDSSIIL TETIAIDWVG RNLYWTDYAL ETIEVSKIDG SHRTVLISKN LTNPRGLALD 
PRMNEHLLFW SDWGHHPRIE RASMDGSMRT VIVQDKIFWP CGLTIDYPNR LLYFMDSYLD 
YMDFCDYNGH HRRQVIASDL IIRHPYALTL FEDSVYWTDR ATRRVMRANK WHGGNQSVVM 
YNIQWPLGIV AVHPSKQPNS VNPCAFSRCS HLCLLSSQGP HFYSCVCPSG WSLSPDLLNC 
LRDDQPFLIT VRQHIIFGIS LNPEVKSNDA MVPIAGIQNG LDVEFDDAEQ YIYWVENPGE 
IHRVKTDGTN RTVFASISMV GPSMNLALDW ISRNLYSTNP RTQSIEVLTL HGDIRYRKTL 
IANDGTALGV GFPIGITVDP ARGKLYWSDQ GTDSGVPAKI ASANMDGTSV KTLFTGNLEH 
LECVTLDIEE QKLYWAVTGR GVIERGNVDG TDRMILVHQL SHPWGIAVHD SFLYYTDEQY 
EVIERVDKAT GANKIVLRDN VPNLRGLQVY HRRNAAESSN GCSNNMNACQ QICLPVPGGL 
FSCACATGFK LNPDNRSCSP YNSFIVVSML SAIRGFSLEL SDHSETMVPV AGQGRNALHV 
DVDVSSGFIY WCDFSSSVAS DNAIRRIKPD GSSLMNIVTH GIGENGVRGI AVDWVAGNLY 
FTNAFVSETL IEVLRINTTY RRVLLKVTVD MPRHIVVDPK NRYLFWADYG QRPKIERSFL 
DCTNRTVLVS EGIVTPRGLA VDRSDGYVYW VDDSLDIIAR IRINGENSEV IRYGSRYPTP 
YGITVFENSI IWVDRNLKKI FQASKEPENT EPPTVIRDNI NWLRDVTIFD KQVQPRSPAE 
VNNNPCLENN GGCSHLCFAL PGLHTPKCDC AFGTLQSDGK NCAISTENFL IFALSNSLRS 
LHLDPENHSP PFQTINVERT VMSLDYDSVS DRIYFTQNLA SGVGQISYAT LSSGIHTPTV 
IASGIGTADG IAFDWITRRI YYSDYLNQMI NSMAEDGSNR TVIARVPKPR AIVLDPCQGY 
LYWADWDTHA KIERATLGGN FRVPIVNSSL VMPSGLTLDY EEDLLYWVDA SLQRIERSTL 
TGVDREVIVN AAVHAFGLTL YGQYIYWTDL YTQRIYRANK YDGSGQIAMT TNLLSQPRGI 
NTVVKNQKQQ CNNPCEQFNG GCSHICAPGP NGAECQCPHE GNWYLANNRK HCIVDNGERC 
GASSFTCSNG RCISEEWKCD NDNDCGDGSD EMESVCALHT CSPTAFTCAN GRCVQYSYRC 
DYYNDCGDGS DEAGCLFRDC NATTEFMCNN RRCIPREFIC NGVDNCHDNN TSDEKNCPDR 
TCQSGYTKCH NSNICIPRVY LCDGDNDCGD NSDENPTYCT THTCSSSEFQ CASGRCIPQH 
WYCDQETDCF DASDEPASCG HSERTCLADE FKCDGGRCIP SEWICDGDND CGDMSDEDKR 
HQCQNQNCSD SEFLCVNDRP PDRRCIPQSW VCDGDVDCTD GYDENQNCTR RTCSENEFTC 
GYGLCIPKIF RCDRHNDCGD YSDERGCLYQ TCQQNQFTCQ NGRCISKTFV CDEDNDCGDG 
SDELMHLCHT PEPTCPPHEF KCDNGRCIEM MKLCNHLDDC LDNSDEKGCG INECHDPSIS 
GCDHNCTDTL TSFYCSCRPG YKLMSDKRTC VDIDECTEMP FVCSQKCENV IGSYICKCAP 
GYLREPDGKT CRQNSNIEPY LIFSNRYYLR NLTIDGYFYS LILEGLDNVV ALDFDRVEKR 
LYWIDTQRQV IERMFLNKTN KETIINHRLP AAESLAVDWV SRKLYWLDAR LDGLFVSDLN 
GGHRRMLAQH CVDANNTFCF DNPRGLALHP QYGYLYWADW GHRAYIGRVG MDGTNKSVII 
STKLEWPNGI TIDYTNDLLY WADAHLGYIE YSDLEGHHRH TVYDGALPHP FAITIFEDTI 
YWTDWNTRTV EKGNKYDGSN RQTLVNTTHR PFDIHVYHPY RQPIVSNPCG TNNGGCSHLC 
LIKPGGKGFT CECPDDFRTL QLSGSTYCMP MCSSTQFLCA NNEKCIPIWW KCDGQKDCSD 
GSDELALCPQ RFCRLGQFQC SDGNCTSPQT LCNAHQNCPD GSDEDRLLCE NHHCDSNEWQ 
CANKRCIPES WQCDTFNDCE DNSDEDSSHC ASRTCRPGQF RCANGRCIPQ AWKCDVDNDC 
GDHSDEPIEE CMSSAHLCDN FTEFSCKTNY RCIPKWAVCN GVDDCRDNSD EQGCEERTCH 
PVGDFRCKNH HCIPLRWQCD GQNDCGDNSD EENCAPRECT ESEFRCVNQQ CIPSRWICDH 
YNDCGDNSDE RDCEMRTCHP EYFQCTSGHC VHSELKCDGS ADCLDASDEA DCPTRFPDGA 
YCQATMFECK NHVCIPPYWK CDGDDDCGDG SDEELHLCLD VPCNSPNRFR CDNNRCIYSH 
EVCNGVDDCG DGTDETEEHC RKPTPKPCTE YEYKCGNGHC IPHDNVCDDA DDCGDWSDEL 
GCNKGKERTC AENICEQNCT QLNEGGFICS CTAGFETNVF DRTSCLDINE CEQFGTCPQH 
CRNTKGSYEC VCADGFTSMS DRPGKRCAAE GSSPLLLLPD NVRIRKYNLS SERFSEYLQD 
EEYIQAVDYD WDPKDIGLSV VYYTVRGEGS RFGAIKRAYI PNFESGRNNL VQEVDLKLKY 
VMQPDGIAVD WVGRHIYWSD VKNKRIEVAK LDGRYRKWLI STDLDQPAAI AVNPKLGLMF 
WTDWGKEPKI ESAWMNGEDR NILVFEDLGW PTGLSIDYLN NDRIYWSDFK EDVIETIKYD 
GTDRRVIAKE AMNPYSLDIF EDQLYWISKE KGEVWKQNKF GQGKKEKTLV VNPWLTQVRI 
FHQLRYNKSV PNLCKQICSH LCLLRPGGYS CACPQGSSFI EGSTTECDAA IELPINLPPP 
CRCMHGGNCY FDETDLPKCK CPSGYTGKYC EMAFSKGISP GTTAVAVLLT ILLIVVIGAL 
AIAGFFHYRR TGSLLPALPK LPSLSSLVKP SENGNGVTFR SGADLNMDIG VSGFGPETAI 
DRSMAMSEDF VMEMGKQPII FENPMYSARD SAVKVVQPIQ VTVSENVDNK NYGSPINPSE 
IVPETNPTSP AADGTQVTKW NLFKRKSKQT TNFENPIYAQ MENEQKESVA ATPPPSPSLP 
AKPKPPSRRD PTPTYSATED TFKDTANLVK EDSEV

Genular Protein ID: 450104531

Symbol: Q7Z5C0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z5C0

Database IDs:

ARBA 11 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 9 Gene3D 3 InterPro 14 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 11 PROSITE-ProRule 3 PeptideAtlas 1 Pfam 5 PharmGKB 1 RefSeq 1 SAM 3 SMART 4 SMR 1 SUPFAM 4

Citations:

PubMed ID: 12713445

Title: Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.

PubMed ID: 12713445

DOI: 10.1042/BJ20021958

Sequence Information:

  • Length: 4655
  • Mass: 521932
  • Checksum: BDFF6846CC129B69
  • Sequence:
    • MDRGPAAVAC TLLLALVACL APASGQECDS AHFRCGSGHC IPADWRCDGT KDCSDDADEI 
GCAVVTCQQG YFKCQSEGQC IPSSWVCDQD QDCDDGSDER QDCSQSTCSS HQITCSNGQC 
IPSEYRCDHV RDCPDGADEN DCQYPTCEQL TCDNGACYNT SQKCDWKVDC RDSSDEINCT 
EICLHNEFSC GNGECIPRAY VCDHDNDCQD GSDEHACNYP TCGGYQFTCP SGRCIYQNWV 
CDGEDDCKDN GDEDGCESGP HDVHKCSPRE WSCPESGRCI SIYKVCDGIL DCPGREDENN 
TSTGKYCSMT LCSALNCQYQ CHETPYGGAC FCPPGYIINH NDSRTCVEFD DCQIWGICDQ 
KCESRPGRHL CHCEEGYILE RGQYCKANDS FGEASIIFSN GRDLLIGDIH GRSFRILVES 
QNRGVAVGVA FHYHLQRVFW TDTVQNKVFS VDINGLNIQE VLNVSVETPE NLAVDWVNNK 
IYLVETKVNR IDMVNLDGSY RVTLITENLG HPRGIAVDPT VGYLFFSDWE SLSGEPKLER 
AFMDGSNRKD LVKTKLGWPA GVTLDMISKR VYWVDSRFDY IETVTYDGIQ RKTVVHGGSL 
IPHPFGVSLF EGQVFFTDWT KMAVLKANKF TETNPQVYYQ ASLRPYGVTV YHSLRQPYAT 
NPCKDNNGGC EQVCVLSHRT DNDGLGFRCK CTFGFQLDTD ERHCIAVQNF LIFSSQVAIR 
GIPFTLSTQE DVMVPVSGNP SFFVGIDFDA QDSTIFFSDM SKHMIFKQKI DGTGREILAA 
NRVENVESLA FDWISKNLYW TDSHYKSISV MRLADKTRRT VVQYLNNPRS VVVHPFAGYL 
FFTDWFRPAK IMRAWSDGSH LLPVINTTLG WPNGLAIDWA ASRLYWVDAY FDKIEHSTFD 
GLDRRRLGHI EQMTHPFGLA IFGEHLFFTD WRLGAIIRVR KADGGEMTVI RSGIAYILHL 
KSYDVNIQTG SNACNQPTHP NGDCSHFCFP VPNFQRVCGC PYGMRLASNH LTCEGDPTNE 
PPTEQCGLFS FPCKNGRCVP NYYLCDGVDD CHDNSDEQLC GTLNNTCSSS AFTCGHGECI 
PAHWRCDKRN DCVDGSDEHN CPTHAPASCL DTQYTCDNHQ CISKNWVCDT DNDCGDGSDE 
KNCNSTETCQ PSQFNCPNHR CIDLSFVCDG DKDCVDGSDE VGCVLNCTAS QFKCASGDKC 
IGVTNRCDGV FDCSDNSDEA GCPTRPPGMC HSDEFQCQED GICIPNFWEC DGHPDCLYGS 
DEHNACVPKT CPSSYFHCDN GNCIHRAWLC DRDNDCGDMS DEKDCPTQPF RCPSWQWQCL 
GHNICVNLSV VCDGIFDCPN GTDESPLCNG NSCSDFNGGC THECVQEPFG AKCLCPLGFL 
LANDSKTCED IDECDILGSC SQHCYNMRGS FRCSCDTGYM LESDGRTCKV TASESLLLLV 
ASQNKIIADS VTSQVHNIYS LVENGSYIVA VDFDSISGRI FWSDATQGKT WSAFQNGTDR 
RVVFDSSIIL TETIAIDWVG RNLYWTDYAL ETIEVSKIDG SHRTVLISKN LTNPRGLALD 
PRMNEHLLFW SDWGHHPRIE RASMDGSMRT VIVQDKIFWP CGLTIDYPNR LLYFMDSYLD 
YMDFCDYNGH HRRQVIASDL IIRHPYALTL FEDSVYWTDR ATRRVMRANK WHGGNQSVVM 
YNIQWPLGIV AVHPSKQPNS VNPCAFSRCS HLCLLSSQGP HFYSCVCPSG WSLSPDLLNC 
LRDDQPFLIT VRQHIIFGIS LNPEVKSNDA MVPIAGIQNG LDVEFDDAEQ YIYWVENPGE 
IHRVKTDGTN RTVFASISMV GPSMNLALDW ISRNLYSTNP RTQSIEVLTL HGDIRYRKTL 
IANDGTALGV GFPIGITVDP ARGKLYWSDQ GTDSGVPAKI ASANMDGTSV KTLFTGNLEH 
LECVTLDIEE QKLYWAVTGR GVIERGNVDG TDRMILVHQL SHPWGIAVHD SFLYYTDEQY 
EVIERVDKAT GANKIVLRDN VPNLRGLQVY HRRNAAESSN GCSNNMNACQ QICLPVPGGL 
FSCACATGFK LNPDNRSCSP YNSFIVVSML SAIRGFSLEL SDHSETMVPV AGQGRNALHV 
DVDVSSGFIY WCDFSSSVAS DNAIRRIKPD GSSLMNIVTH GIGENGVRGI AVDWVAGNLY 
FTNAFVSETL IEVLRINTTY RRVLLKVTVD MPRHIVVDPK NRYLFWADYG QRPKIERSFL 
DCTNRTVLVS EGIVTPRGLA VDRSDGYVYW VDDSLDIIAR IRINGENSEV IRYGSRYPTP 
YGITVFENSI IWVDRNLKKI FQASKEPENT EPPTVIRDNI NWLRDVTIFD KQVQPRSPAE 
VNNNPCLENN GGCSHLCFAL PGLHTPKCDC AFGTLQSDGK NCAISTENFL IFALSNSLRS 
LHLDPENHSP PFQTINVERT VMSLDYDSVS DRIYFTQNLA SGVGQISYAT LSSGIHTPTV 
IASGIGTADG IAFDWITRRI YYSDYLNQMI NSMAEDGSNR TVIARVPKPR AIVLDPCQGY 
LYWADWDTHA KIERATLGGN FRVPIVNSSL VMPSGLTLDY EEDLLYWVDA SLQRIERSTL 
TGVDREVIVN AAVHAFGLTL YGQYIYWTDL YTQRIYRANK YDGSGQIAMT TNLLSQPRGI 
NTVVKNQKQQ CNNPCEQFNG GCSHICAPGP NGAECQCPHE GNWYLANNRK HCIVDNGERC 
GASSFTCSNG RCISEEWKCD NDNDCGDGSD EMESVCALHT CSPTAFTCAN GRCVQYSYRC 
DYYNDCGDGS DEAGCLFRDC NATTEFMCNN RRCIPREFIC NGVDNCHDNN TSDEKNCPDR 
TCQSGYTKCH NSNICIPRVY LCDGDNDCGD NSDENPTYCT THTCSSSEFQ CASGRCIPQH 
WYCDQETDCF DASDEPASCG HSERTCLADE FKCDGGRCIP SEWICDGDND CGDMSDEDKR 
HQCQNQNCSD SEFLCVNDRP PDRRCIPQSW VCDGDVDCTD GYDENQNCTR RTCSENEFTC 
GYGLCIPKIF RCDRHNDCGD YSDERGCLYQ TCQQNQFTCQ NGRCISKTFV CDEDNDCGDG 
SDELMHLCHT PEPTCPPHEF KCDNGRCIEM MKLCNHLDDC LDNSDEKGCG INECHDPSIS 
GCDHNCTDTL TSFYCSCRPG YKLMSDKRTC VDIDECTEMP FVCSQKCENV IGSYICKCAP 
GYLREPDGKT CRQNSNIEPY LIFSNRYYLR NLTIDGYFYS LILEGLDNVV ALDFDRVEKR 
LYWIDTQRQV IERMFLNKTN KETIINHRLP AAESLAVDWV SRKLYWLDAR LDGLFVSDLN 
GGHRRMLAQH CVDANNTFCF DNPRGLALHP QYGYLYWADW GHRAYIGRVG MDGTNKSVII 
STKLEWPNGI TIDYTNDLLY WADAHLGYIE YSDLEGHHRH TVYDGALPHP FAITIFEDTI 
YWTDWNTRTV EKGNKYDGSN RQTLVNTTHR PFDIHVYHPY RQPIVSNPCG TNNGGCSHLC 
LIKPGGKGFT CECPDDFRTL QLSGSTYCMP MCSSTQFLCA NNEKCIPIWW KCDGQKDCSD 
GSDELALCPQ RFCRLGQFQC SDGNCTSPQT LCNAHQNCPD GSDEDRLLCE NHHCDSNEWQ 
CANKRCIPES WQCDTFNDCE DNSDEDSSHC ASRTCRPGQF RCANGRCIPQ AWKCDVDNDC 
GDHSDEPIEE CMSSAHLCDN FTEFSCKTNY RCIPKWAVCN GVDDCRDNSD EQGCEERTCH 
PVGDFRCKNH HCIPLRWQCD GQNDCGDNSD EENCAPRECT ESEFRCVNQQ CIPSRWICDH 
YNDCGDNSDE RDCEMRTCHP EYFQCTSGHC VHSELKCDGS ADCLDASDEA DCPTRFPDGA 
YCQATMFECK NHVCIPPYWK CDGDDDCGDG SDEELHLCLD VPCNSPNRFR CDNNRCIYSH 
EVCNGVDDCG DGTDETEEHC RKPTPKPCTE YEYKCGNGHC IPHDNVCDDA DDCGDWSDEL 
GCNKGKERTC AENICEQNCT QLNEGGFICS CTAGFETNVF DRTSCLDINE CEQFGTCPQH 
CRNTKGSYEC VCADGFTSMS DRPGKRCAAE GSSPLLLLPD NVRIRKYNLS SERFSEYLQD 
EEYIQAVDYD WDPEDIGLSV VYYTVRGEGS RFGAIKRAYI PNFESGRNNL VQEVDLKLKY 
VMQPDGIAVD WVGRHIYWSD VKNKRIEVAK LDGRYRKWLI STDLDQPAAI AVNPKLGLMF 
WTDWGKEPKL ESAWMNGEDR NILVFEDLGW PTGLSIDYLN NDRIYWSDFK EDVIETIKYD 
GTDRRVIAKE AMNPYSLDIF EDQLYWISKE KGEVWKQNKF GQGKKEKTLV VNPWLTQVRI 
FHQLRYNKSV PNLCKQICSH LCLLRPGGYS CACPQGSSFI EGSTTECDAA IELPINLPPP 
CRCMHGGNCY FDETDLPKCK CPSGYTGKYC EMAFSKGISP GTTAVAVLLT ILLIVVIGAL 
AIAGFFHYRR TGSLLPALPK LPSLSSLVKP SENGNGVTFR SGADLNMDIG VSGFGPETAI 
DRSMAMSEDF VMEMGKQPII FENPMYSARD SAVKVVQPIQ VTVSENVDNK NYGSPINPSE 
IVPETNPTSP AADGTQVTKW NLFKRKSKQT TNFENPIYAQ MENEQKESVA ATPPPSPSLP 
AKPKPPSRRD PTPTYSATED TFKDTANLVK EDSEV

Genular Protein ID: 499027518

Symbol: Q7Z5C1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q7Z5C1

Database IDs:

ARBA 11 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 3 InterPro 14 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 11 PROSITE-ProRule 3 PeptideAtlas 1 Pfam 5 PharmGKB 1 RefSeq 1 SAM 3 SMART 4 SUPFAM 4

Citations:

PubMed ID: 8706697

Title: Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties.

PubMed ID: 8706697

DOI: 10.1111/j.1432-1033.1996.0132u.x

Sequence Information:

  • Length: 4655
  • Mass: 521982
  • Checksum: E0AFDCF1AC9F235D
  • Sequence:
    • MDRGPAAVAC TLLLALVACL APASGQECDS AHFRCGSGHC IPADWRCDGT KDCSDDADEI 
GCAVVTCQQG YFKCQSEGQC IPSSWVCDQD QDCDDGSDER QDCSQSTCSS HQITCSNGQC 
IPSEYRCDHV RDCPDGADEN DCQYPTCEQL TCDNGACYNT SQKCDWKVDC RDSSDEINCT 
EICLHNEFSC GNGECIPRAY VCDHDNDCQD GSDEHACNYP TCGGYQFTCP SGRCIYQNWV 
CDGEDDCKDN GDEDGCESGP HDVHKCSPRE WSCPESGRCI SIYKVCDGIL DCPGREDENN 
TSTGKYCSMT LCSALNCQYQ CHETPYGGAC FCPPGYIINH NDSRTCVEFD DCQIWGICDQ 
KCESRPGRHL CHCEEGYILE RGQYCKANDS FGEASIIFSN GRDLLIGDIH GRSFRILVES 
QNRGVAVGVA FHYHLQRVFW TDTVQNKVFS VDINGLNIQE VLNVSVETPE NLAVDWVNNK 
IYLVETKVNR IDMVNLDGSY RVTLITENLG HPRGIAVDPT VGYLFFSDWE SLSGEPKLER 
AFMDGSNRKD LVKTKLGWPA GVTLDMISKR VYWVDSRFDY IETVTYDGIQ RKTVVHGGSL 
IPHPFGVSLF EGQVFFTDWT KMAVLKANKF TETNPQVYYQ ASLRPYGVTV YHSLRQPYAT 
NPCKDNNGGC EQVCVLSHRT DNDGLGFRCK CTFGFQLDTD ERHCIAVQNF LIFSSQVAIR 
GIPFTLSTQE DVMVPVSGNP SFFVGIDFDA QDSTIFFSDM SKHMIFKQKI DGTGREILAA 
NRVENVESLA FDWISKNLYW TDSHYKSISV MRLADKTRRT VVQYLNNPRS VVVHPFAGYL 
FFTDWFRPAK IMRAWSDGSH LLPVINTTLG WPNGLAIDWA ASRLYWVDAY FDKIEHSTFD 
GLDRRRLGHI EQMTHPFGLA IFGEHLFFTD WRLGAIIRVR KADGGEMTVI RSGIAYILHL 
KSYDVNIQTG SNACNQPTHP NGDCSHFCFP VPNFQRVCGC PYGMRLASNH LTCEGDPTNE 
PPTEQCGLFS FPCKNGRCVP NYYLCDGVDD CHDNSDEQLC GTLNNTCSSS AFTCGHGECI 
PAHWRCDKRN DCVDGSDEHN CPTHAPASCL DTQYTCDNHQ CISKNWVCDT DNDCGDGSDE 
KNCNSTETCQ PSQFNCPNHR CIDLSFVCDG DKDCVDGSDE VGCVLNCTAS QFKCASGDKC 
IGVTNRCDGV FDCSDNSDEA GCPTRPPGMC HSDEFQCQED GICIPNFWEC DGHPDCLYGS 
DEHNACVPKT CPSSYFHCDN GNCIHRXWLC DRDNDCGDMS DEKDCPTQPF RCPSWQWQCL 
GHNICVNLSV VCDGIFDCPN GTDESPLCNG NSCSDFNGGC THECVQEPFG AKCLCPLGFL 
LANDSKTCED IDECDILGSC SQHCYNMRGS FRCSCDTGYM LESDGRTCKV TASESLLLLV 
ASQNKIIADS VTSQVHNIYS LVENGSYIVA VDFDSISGRI FWSDATQGKT WSAFQNGTDR 
RVVFDSSIIL TETIAIDWVG RNLYWTDYAL ETIEVSKIDG SHRTVLISKN LTNPRGLALD 
PRMNEHLLFW SDWGHHPRIE RASMDGSMRT VIVQDKIFWP CGLTIDYPNR LLYFMDSYLD 
YMDFCDYNGH HRRQVIASDL IIRHPYALTL FEDSVYWTDR ATRRVMRANK WHGGNQSVVM 
YNIQWPLGIV AVHPSKQPNS VNPCAFSRCS HLCLLSSQGP HFYSCVCPSG WSLSPDLLNC 
LRDDQPFLIT VRQHIIFGIS LNPEVKSNDA MVPIAGIQNG LDVEFDDAEQ YIYWVENPGE 
IHRVKTDGTN RTVFASISMV GPSMNLALDW ISRNLYSTNP RTQSIEVLTL HGDIRYRKTL 
IANDGTALGV GFPIGITVDP ARGKLYWSDQ GTDSGVPAKI ASANMDGTSV KTLFTGNLEH 
LECVTLDIEE QKLYWAVTGR GVIERGNVDG TDRMILVHQL SHPWGIAVHD SFLYYTDEQY 
EVIERVDKAT GANKIVLRDN VPNLRGLQVY HRRNAAESSN GCSNNMNACQ QICLPVPGGL 
FSCACATGFK LNPDNRSCSP YNSFIVVSML SAIRGFSLEL SDHSETMVPV AGQGRNALHV 
DVDVSSGFIY WCDFSSSVAS DNAIRRIKPD GSSLMNIVTH GIGENGVRGI AVDWVAGNLY 
FTNAFVSETL IEVLRINTTY RRVLLKVTVD MPRHIVVDPK NRYLFWADYG QRPKIERSFL 
DCTNRTVLVS EGIVTPRGLA VDRSDGYVYW VDDSLDIIAR IRINGENSEV IRYGSRYPTP 
YGITVFENSI IWVDRNLKKI FQASKEPENT EPPTVIRDNI NWLRDVTIFD KQVQPRSPAE 
VNNNPCLENN GGCSHLCFAL PGLHTPKCDC AFGTLQSDGK NCAISTENFL IFALSNSLRS 
LHLDPENHSP PFQTINVERT VMSLDYDSVS DRIYFTQNLA SGVGQISYAT LSSGIHTPTV 
IASGIGTADG IAFDWITRRI YYSDYLNQMI NSMAEDGSNR TVIARVPKPR AIVLDPCQGY 
LYWADWDTHA KIERATLGGN FRVPIVNSSL VMPSGLTLDY EEDLLYWVDA SLQRIERSTL 
TGVDREVIVN AAVHAFGLTL YGQYIYWTDL YTQRIYRANK YDGSGQIAMT TNLLSQPRGI 
NTVVKNQKQQ CNNPCEQFNG GCSHICAPGP NGAECQCPHE GNWYLANNRK HCIVDNGERC 
GASSFTCSNG RCISEEWKCD NDNDCGDGSD EMESVCALHT CSPTAFTCAN GRCVQYSYRC 
DYYNDCGDGS DEAGCLFRDC NATTEFMCNN RRCIPREFIC NGVDNCHDNN TSDEKNCPDR 
TCQSGYTKCH NSNICIPRVY LCDGDNDCGD NSDENPTYCT THTCSSSEFQ CTSGRCIPQH 
WYCDQETDCF DASDEPASCG HSERTCLADE FKCDGGRCIP SEWICDGDND CGDMSDEDKR 
HQCQNQNCSD SEFLCVNDRP PDRRCIPQSW VCDGDVDCTD GYDENQNCTR RTCSENEFTC 
GYGLCIPKIF RCDRHNDCGD YSDERGCLYQ TCQQNQFTCQ NGRCISKTFV CDEDNDCGDG 
SDELMHLCHT PEPTCPPHEF KCDNGRCIEM MKLCNHLDDC LDNSDEKGCG INECHDPSIS 
GCDHNCTDTL TSFYCSCRPG YKLMSDKRTC VDIDECTEMP FVCSQKCENV IGSYICKCAP 
GYLREPDGKT CRQNSNIEPY LIFSNRYYLR NLTIDGYFYS LILEGLDNVV ALDFDRVEKR 
LYWIDTQRQV IERMFLNKTN KETIINHRLP AAESLAVDWV SRKLYWLDAR LDGLFVSDLN 
GGHRRMLAQH CVDANNTFCF DNPRGLALHP QYGYLYWADW GHRAYIGRVG MDGTNKSVII 
STKLEWPNGI TIDYTNDLLY WADAHLGYIE YSDLEGHHRH TVYDGALPHP FAITIFEDTI 
YWTDWNTRTV EKGNKYDGSN RQTLVNTTHR PFDIHVYHPY RQPIVSNPCG TNNGGCSHLC 
LIKPGGKGFT CECPDDFRTL QLSGSTYCMP MCSSTQFLCA NNEKCIPIWW KCDGQKDCSD 
GSDELALCPQ RFCRLGQFQC SDGNCTSPQT LCNAHQNCPD GSDEDRLLCE NHHCDSNEWQ 
CANKRCIPES WQCDTFNDCE DNSDEDSSHC ASRTCRPGQF RCANGRCIPQ AWKCDVDNDC 
GDHSDEPIEE CMSSAHLCDN FTEFSCKTNY RCIPKWAVCN GVDDCRDNSD EQGCEERTCH 
PVGDFRCKNH HCIPLRWQCD GQNDCGDNSD EENCAPRECT ESEFRCVNQQ CIPSRWICDH 
YNDCGDNSDE RDCEMRTCHP EYFQCTSGHC VHSELKCDGS ADCLDASDEA DCPTRFPDGA 
YCQATMFECK NHVCIPPYWK CDGDDDCGDG SDEELHLCLD VPCNSPNRFR CDNNRCIYSH 
EVCNGVDDCG DGTDETEEHC RKPTPKPCTE YEYKCGNGHC IPHDNVCDDA DDCGDWSDEL 
GCNKGKERTC AENICEQNCT QLNEGGFICS CTAGFETNVF DRTSCLDINE CEQFGTCPQH 
CRNTKGSYEC VCADGFTSMS DRPGKRCAAE GSSPLLLLPD NVRIRKYNLS SERFSEYLQD 
EEYIQAVDYD WDPXDIGLSV VYYTVRGEGS RFGAIKRAYI PNFESGRNNL VQEVDLKLKY 
VMQPDGIAVD WVGRHIYWSD VKNKRIEVAK LDGRYRKWLI STDLDQPAAI AVNPKLGLMF 
WTDWGKEPKX ESAWMNGEDR NILVFEDLGW PTGLSIDYLN NDRIYWSDFK EDVIETIKYD 
GTDRRVIAKE AMNPYSLDIF EDQLYWISKE KGEVWKQNKF GQGKKEKTLV VNPWLTQVRI 
FHQLRYNKSV PNLCKQICSH LCLLRPGGYS CACPQGSSFI EGSTTECDAA IELPINLPPP 
CRCMHGGNCY FDETDLPKCK CPSGYTGKYC EMAFSKGISP GTTAVAVLLT ILLIVVIGAL 
AIAGFFHYRR TGSLLPALPK LPSLSSLVKP SENGNGVTFR SGADLNMDIG VSGFGPETAI 
DRSMAMSEDF VMEMGKQPII FENPMYSARD SAVKVVQPIQ VTVSENVDNK NYGSPINPSE 
IVPETNPTSP AADGTQVTKW NLFKRKSKQT TNFENPIYAQ MENEQKESVA ATPPPSPSLP 
AKPKPPSRRD PTPTYSATED TFKDTANLVK EDSEV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.