Details for: KCNJ6
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stellate neuron (CL0000122)
Fold Change: 4.8
Marker Score: 25806 - Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 4.26
Marker Score: 8807 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 3.07
Marker Score: 16102 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 2.71
Marker Score: 7738 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.58
Marker Score: 4898 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: 2.53
Marker Score: 10500 - Cell Name: endocrine cell (CL0000163)
Fold Change: 2.43
Marker Score: 1255 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: 2.38
Marker Score: 35543 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: 2.38
Marker Score: 18216 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 2.36
Marker Score: 47036 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 2.21
Marker Score: 3717 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 2.19
Marker Score: 80970 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 2.19
Marker Score: 10115 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.13
Marker Score: 19999 - Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.08
Marker Score: 8060 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 2.07
Marker Score: 21425 - Cell Name: neuron (CL0000540)
Fold Change: 2.05
Marker Score: 8360 - Cell Name: macroglial cell (CL0000126)
Fold Change: 2.05
Marker Score: 4705 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 2.03
Marker Score: 1178 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.97
Marker Score: 121192 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.93
Marker Score: 73325 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.87
Marker Score: 17789 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.86
Marker Score: 15977 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.61
Marker Score: 1170 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.6
Marker Score: 3251 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 1.56
Marker Score: 5234 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.48
Marker Score: 2286 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168265 - Cell Name: granule cell (CL0000120)
Fold Change: 1.39
Marker Score: 10493 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.35
Marker Score: 758 - Cell Name: A2 amacrine cell (CL0004219)
Fold Change: 1.32
Marker Score: 419 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.32
Marker Score: 20623 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 1.26
Marker Score: 856 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.2
Marker Score: 483 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.19
Marker Score: 411 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.19
Marker Score: 2805 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 1.16
Marker Score: 607 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.15
Marker Score: 4813 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.13
Marker Score: 680 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.09
Marker Score: 421 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.08
Marker Score: 483 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 1.04
Marker Score: 35226 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 1.04
Marker Score: 6240 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.03
Marker Score: 496 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71816 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48041 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.99
Marker Score: 411 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 508 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30407 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 461 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.96
Marker Score: 457 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.95
Marker Score: 1176 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2413 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.94
Marker Score: 349 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.93
Marker Score: 374 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5324 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.93
Marker Score: 426 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2742 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.91
Marker Score: 326 - Cell Name: oocyte (CL0000023)
Fold Change: 0.89
Marker Score: 220 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5287 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.87
Marker Score: 279 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.83
Marker Score: 1685 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 0.81
Marker Score: 393 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1264 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 703 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 396 - Cell Name: PP cell (CL0000696)
Fold Change: 0.74
Marker Score: 167 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.7
Marker Score: 218 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.62
Marker Score: 162 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: 0.61
Marker Score: 572 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.61
Marker Score: 2525 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6
Marker Score: 387 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.59
Marker Score: 713 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.58
Marker Score: 183 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.56
Marker Score: 247 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 0.56
Marker Score: 184 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 442 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.55
Marker Score: 174 - Cell Name: fat cell (CL0000136)
Fold Change: 0.51
Marker Score: 283 - Cell Name: retina horizontal cell (CL0000745)
Fold Change: 0.5
Marker Score: 482 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.45
Marker Score: 234 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.43
Marker Score: 255 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.43
Marker Score: 418 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.43
Marker Score: 120 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.42
Marker Score: 245 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.41
Marker Score: 405.5 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.4
Marker Score: 136 - Cell Name: microglial cell (CL0000129)
Fold Change: 0.39
Marker Score: 714.5 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.38
Marker Score: 167 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.38
Marker Score: 425 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.36
Marker Score: 216 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 0.35
Marker Score: 1243 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.34
Marker Score: 88 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.34
Marker Score: 2234 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.34
Marker Score: 405 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.33
Marker Score: 284 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 0.33
Marker Score: 377 - Cell Name: glial cell (CL0000125)
Fold Change: 0.32
Marker Score: 357 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.3
Marker Score: 123
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Other Information
Genular Protein ID: 3252028203
Symbol: KCNJ6_HUMAN
Name: G protein-activated inward rectifier potassium channel 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7592809
Title: Pancreatic islet cells express a family of inwardly rectifying K+ channel subunits which interact to form G-protein-activated channels.
PubMed ID: 7592809
PubMed ID: 10659995
Title: Co-expression of human Kir3 subunits can yield channels with different functional properties.
PubMed ID: 10659995
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7796919
Title: Characterization and variation of a human inwardly-rectifying-K-channel gene (KCNJ6): a putative ATP-sensitive K-channel subunit.
PubMed ID: 7796919
PubMed ID: 7729621
Title: Isolation of a cDNA clone encoding a KATP channel-like protein expressed in insulin-secreting cells, localization of the human gene to chromosome band 21q22.1, and linkage studies with NIDDM.
PubMed ID: 7729621
PubMed ID: 25620207
Title: Keppen-Lubinsky syndrome is caused by mutations in the inwardly rectifying K+ channel encoded by KCNJ6.
PubMed ID: 25620207
Sequence Information:
- Length: 423
- Mass: 48451
- Checksum: 7A02F6B0FBF8B7D4
- Sequence:
MAKLTESMTN VLEGDSMDQD VESPVAIHQP KLPKQARDDL PRHISRDRTK RKIQRYVRKD GKCNVHHGNV RETYRYLTDI FTTLVDLKWR FNLLIFVMVY TVTWLFFGMI WWLIAYIRGD MDHIEDPSWT PCVTNLNGFV SAFLFSIETE TTIGYGYRVI TDKCPEGIIL LLIQSVLGSI VNAFMVGCMF VKISQPKKRA ETLVFSTHAV ISMRDGKLCL MFRVGDLRNS HIVEASIRAK LIKSKQTSEG EFIPLNQTDI NVGYYTGDDR LFLVSPLIIS HEINQQSPFW EISKAQLPKE ELEIVVILEG MVEATGMTCQ ARSSYITSEI LWGYRFTPVL TLEDGFYEVD YNSFHETYET STPSLSAKEL AELASRAELP LSWSVSSKLN QHAELETEEE EKNLEEQTER NGDVANLENE SKV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.