Details for: TCF7L2

Gene ID: 6934

Symbol: TCF7L2

Ensembl ID: ENSG00000148737

Description: transcription factor 7 like 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 438.8434
    Cell Significance Index: -68.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 258.1577
    Cell Significance Index: -65.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 151.1789
    Cell Significance Index: -71.3800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 130.7775
    Cell Significance Index: -67.2700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 106.3378
    Cell Significance Index: -71.3600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 62.3309
    Cell Significance Index: -59.5100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 55.4034
    Cell Significance Index: -68.3100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 25.8692
    Cell Significance Index: -69.3000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 21.5618
    Cell Significance Index: -47.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.4073
    Cell Significance Index: -68.6900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 5.0586
    Cell Significance Index: 98.7300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 5.0432
    Cell Significance Index: 34.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.1591
    Cell Significance Index: 233.3900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 3.6594
    Cell Significance Index: 46.0800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 3.2220
    Cell Significance Index: 68.8700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.9769
    Cell Significance Index: 205.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.7244
    Cell Significance Index: 540.6700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.5919
    Cell Significance Index: 64.7900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.5708
    Cell Significance Index: 43.3100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.8943
    Cell Significance Index: 52.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.6750
    Cell Significance Index: 75.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5324
    Cell Significance Index: 44.1500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.4903
    Cell Significance Index: 9.2600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.4067
    Cell Significance Index: 193.1800
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.3237
    Cell Significance Index: 11.7500
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 1.2037
    Cell Significance Index: 5.2400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1474
    Cell Significance Index: 88.0500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.1472
    Cell Significance Index: 30.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0444
    Cell Significance Index: 103.3100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0401
    Cell Significance Index: 939.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0216
    Cell Significance Index: 204.9400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.8521
    Cell Significance Index: 12.2600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8079
    Cell Significance Index: 441.2300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.7416
    Cell Significance Index: 10.3700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.6874
    Cell Significance Index: 10.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6429
    Cell Significance Index: 79.0600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.6177
    Cell Significance Index: 8.8700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5491
    Cell Significance Index: 242.7700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4370
    Cell Significance Index: 20.5400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.4291
    Cell Significance Index: 14.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4199
    Cell Significance Index: 14.7600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3913
    Cell Significance Index: 70.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.3683
    Cell Significance Index: 693.4000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3464
    Cell Significance Index: 44.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3389
    Cell Significance Index: 215.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2944
    Cell Significance Index: 7.8600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2929
    Cell Significance Index: 14.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2283
    Cell Significance Index: 81.8800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.1772
    Cell Significance Index: 272.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1381
    Cell Significance Index: 62.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1219
    Cell Significance Index: 224.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1052
    Cell Significance Index: 143.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0858
    Cell Significance Index: 2.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0646
    Cell Significance Index: 44.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0338
    Cell Significance Index: 2.3900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0078
    Cell Significance Index: 0.1700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0026
    Cell Significance Index: -0.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0277
    Cell Significance Index: -17.2900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0444
    Cell Significance Index: -32.8600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0538
    Cell Significance Index: -9.1900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0553
    Cell Significance Index: -40.5400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0664
    Cell Significance Index: -3.1000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0801
    Cell Significance Index: -60.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0806
    Cell Significance Index: -45.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1228
    Cell Significance Index: -15.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1765
    Cell Significance Index: -9.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1854
    Cell Significance Index: -53.3400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1911
    Cell Significance Index: -2.8200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1983
    Cell Significance Index: -41.7700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2045
    Cell Significance Index: -29.7200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2381
    Cell Significance Index: -6.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2787
    Cell Significance Index: -4.6600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2947
    Cell Significance Index: -30.1000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3152
    Cell Significance Index: -36.7300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.3408
    Cell Significance Index: -37.0700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3540
    Cell Significance Index: -40.5600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3717
    Cell Significance Index: -38.7000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3782
    Cell Significance Index: -5.1600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.3906
    Cell Significance Index: -2.4100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4043
    Cell Significance Index: -46.1500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4226
    Cell Significance Index: -9.0000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5099
    Cell Significance Index: -38.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.6008
    Cell Significance Index: -70.8500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.6022
    Cell Significance Index: -12.6100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.6425
    Cell Significance Index: -43.2100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.6510
    Cell Significance Index: -17.7200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.7465
    Cell Significance Index: -48.1600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7621
    Cell Significance Index: -60.3600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.8239
    Cell Significance Index: -50.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8553
    Cell Significance Index: -37.8300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8591
    Cell Significance Index: -52.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.8845
    Cell Significance Index: -46.0700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.9155
    Cell Significance Index: -15.8300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9357
    Cell Significance Index: -29.9700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.9923
    Cell Significance Index: -14.6500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.0336
    Cell Significance Index: -39.1400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -1.1043
    Cell Significance Index: -16.8000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.1252
    Cell Significance Index: -70.9200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1598
    Cell Significance Index: -10.6800
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -1.2056
    Cell Significance Index: -12.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** * The TCF7L2 gene encodes a transcription factor that binds to β-catenin, a key component of the Wnt/β-catenin signaling pathway. * The TCF7L2 gene is highly expressed in immune cells, including T cells, B cells, and macrophages. * TCF7L2 is also expressed in endocrine cells, such as pancreatic β-cells and insulin-producing cells. * The gene is involved in the regulation of glucose homeostasis, insulin secretion, and pancreatic development. * Variants of the TCF7L2 gene have been associated with several diseases, including type 2 diabetes, rheumatoid arthritis, and certain types of cancer. **Pathways and Functions:** * The Wnt/β-catenin signaling pathway: TCF7L2 regulates the activity of β-catenin, which is a key component of this pathway. The Wnt/β-catenin pathway is involved in various cellular processes, including cell proliferation, differentiation, and survival. * Immune regulation: TCF7L2 is involved in the regulation of immune responses, including the activation and differentiation of immune cells. * Metabolic homeostasis: TCF7L2 regulates glucose homeostasis, insulin secretion, and pancreatic development. * Epithelial-to-mesenchymal transition (EMT): TCF7L2 is involved in the regulation of EMT, a process that involves the transformation of epithelial cells into mesenchymal cells. * DNA binding: TCF7L2 binds to specific DNA sequences, regulating the expression of target genes. **Clinical Significance:** * Type 2 diabetes: Variants of the TCF7L2 gene have been associated with an increased risk of developing type 2 diabetes. * Rheumatoid arthritis: TCF7L2 has been implicated in the pathogenesis of rheumatoid arthritis, a chronic autoimmune disease. * Certain types of cancer: Variants of the TCF7L2 gene have been associated with an increased risk of developing certain types of cancer, including colorectal cancer and pancreatic cancer. * Autoimmune diseases: TCF7L2 has been implicated in the pathogenesis of autoimmune diseases, including multiple sclerosis and lupus. * Immunotherapy: TCF7L2 is a potential target for immunotherapy, as it is involved in the regulation of immune responses. In conclusion, the TCF7L2 gene is a key player in immune regulation and metabolic homeostasis. Variants of the gene have been associated with several diseases, including type 2 diabetes, rheumatoid arthritis, and certain types of cancer. Further research is needed to fully understand the role of TCF7L2 in human disease and to explore its potential as a therapeutic target.

Genular Protein ID: 1582725621

Symbol: TF7L2_HUMAN

Name: Transcription factor 7-like 2

UniProtKB Accession Codes:

Q9NQB0 B4DRJ8 B9X074 C6ZRJ8 C6ZRK0 E2GH14 E2GH19 E2GH20 E2GH24 E2GH25 E9PFH9 F8W742 F8W7T5 O00185 Q9NQB1 Q9NQB2 Q9NQB3 Q9NQB4 Q9NQB5 Q9NQB6 Q9NQB7 Q9ULC2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EMBL 85 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 46 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 13 Pumba 1 RNAct 1 Reactome 11 RefSeq 13 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9065401

Title: Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.

PubMed ID: 9065401

DOI: 10.1126/science.275.5307.1784

PubMed ID: 10919662

Title: The human T cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines.

PubMed ID: 10919662

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

PubMed ID: 21256126

Title: Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells.

PubMed ID: 21256126

DOI: 10.1016/j.yexcr.2011.01.015

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9727977

Title: Identification of c-MYC as a target of the APC pathway.

PubMed ID: 9727977

DOI: 10.1126/science.281.5382.1509

PubMed ID: 9916915

Title: Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.

PubMed ID: 9916915

DOI: 10.1016/s0002-9440(10)65247-9

PubMed ID: 10080941

Title: Identification of Tcf4 residues involved in high-affinity beta-catenin binding.

PubMed ID: 10080941

DOI: 10.1006/bbrc.1999.0379

PubMed ID: 11266540

Title: All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

PubMed ID: 11266540

DOI: 10.1093/nar/29.7.1410

PubMed ID: 12408868

Title: The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.

PubMed ID: 12408868

DOI: 10.1016/s0092-8674(02)01014-0

PubMed ID: 12727872

Title: Sumoylation is involved in beta-catenin-dependent activation of Tcf-4.

PubMed ID: 12727872

DOI: 10.1093/emboj/cdg204

PubMed ID: 12446687

Title: Identification of a promoter-specific transcriptional activation domain at the C-terminus of the Wnt effector protein T-cell factor 4.

PubMed ID: 12446687

DOI: 10.1074/jbc.m210081200

PubMed ID: 12556497

Title: Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.

PubMed ID: 12556497

DOI: 10.1128/mcb.23.4.1379-1389.2003

PubMed ID: 16714285

Title: NARF, an nemo-like kinase (NLK)-associated ring finger protein regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor (TCF/LEF).

PubMed ID: 16714285

DOI: 10.1074/jbc.m602089200

PubMed ID: 16415884

Title: Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.

PubMed ID: 16415884

DOI: 10.1038/ng1732

PubMed ID: 16434966

Title: The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals.

PubMed ID: 16434966

DOI: 10.1038/sj.onc.1209380

PubMed ID: 17873903

Title: Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.

PubMed ID: 17873903

DOI: 10.1038/sj.onc.1210801

PubMed ID: 19816403

Title: The kinase TNIK is an essential activator of Wnt target genes.

PubMed ID: 19816403

DOI: 10.1038/emboj.2009.285

PubMed ID: 19443654

Title: MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation.

PubMed ID: 19443654

DOI: 10.1074/jbc.m109.005017

PubMed ID: 19304756

Title: Dazap2 modulates transcription driven by the Wnt effector TCF-4.

PubMed ID: 19304756

DOI: 10.1093/nar/gkp179

PubMed ID: 21454679

Title: Zipper-interacting protein kinase (ZIPK) modulates canonical Wnt/beta-catenin signaling through interaction with Nemo-like kinase and T-cell factor 4 (NLK/TCF4).

PubMed ID: 21454679

DOI: 10.1074/jbc.m110.189829

PubMed ID: 22699938

Title: Kindlin 2 forms a transcriptional complex with beta-catenin and TCF4 to enhance Wnt signalling.

PubMed ID: 22699938

DOI: 10.1038/embor.2012.88

PubMed ID: 22155184

Title: Beta-catenin inhibits promyelocytic leukemia protein tumor suppressor function in colorectal cancer cells.

PubMed ID: 22155184

DOI: 10.1053/j.gastro.2011.11.041

PubMed ID: 22258766

Title: SPINDLIN1 promotes cancer cell proliferation through activation of WNT/TCF-4 signaling.

PubMed ID: 22258766

DOI: 10.1158/1541-7786.mcr-11-0440

PubMed ID: 22304967

Title: XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling.

PubMed ID: 22304967

DOI: 10.1016/j.molcel.2011.12.032

PubMed ID: 24589551

Title: Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1.

PubMed ID: 24589551

DOI: 10.1101/gad.233239.113

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24390345

Title: Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico.

PubMed ID: 24390345

DOI: 10.1038/nature12828

PubMed ID: 28829046

Title: Twa1/Gid8 is a beta-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis.

PubMed ID: 28829046

DOI: 10.1038/cr.2017.107

PubMed ID: 29061846

Title: A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1.

PubMed ID: 29061846

DOI: 10.1074/jbc.m117.814913

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29739711

Title: SOX30 Inhibits Tumor Metastasis through Attenuating Wnt-Signaling via Transcriptional and Posttranslational Regulation of beta-Catenin in Lung Cancer.

PubMed ID: 29739711

DOI: 10.1016/j.ebiom.2018.04.026

PubMed ID: 11713475

Title: Tcf4 can specifically recognize beta-catenin using alternative conformations.

PubMed ID: 11713475

DOI: 10.1038/nsb718

PubMed ID: 11713476

Title: Structure of a human Tcf4-beta-catenin complex.

PubMed ID: 11713476

DOI: 10.1038/nsb720

PubMed ID: 17052462

Title: Crystal structure of a beta-catenin/BCL9/Tcf4 complex.

PubMed ID: 17052462

DOI: 10.1016/j.molcel.2006.09.001

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 619
  • Mass: 67919
  • Checksum: 4DD2D3CC814AE16E
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTLHF QSGSTHYSAY KTIEHQIAVQ YLQMKWPLLD VQAGSLQSRQ ALKDARSPSP 
AHIVSNKVPV VQHPHHVHPL TPLITYSNEH FTPGNPPPHL PADVDPKTGI PRPPHPPDIS 
PYYPLSPGTV GQIPHPLGWL VPQQGQPVYP ITTGGFRHPY PTALTVNASM SRFPPHMVPP 
HHTLHTTGIP HPAIVTPTVK QESSQSDVGS LHSSKHQDSK KEEEKKKPHI KKPLNAFMLY 
MKEMRAKVVA ECTLKESAAI NQILGRRWHA LSREEQAKYY ELARKERQLH MQLYPGWSAR 
DNYGKKKKRK RDKQPGETNE HSECFLNPCL SLPPITDLSA PKKCRARFGL DQQNNWCGPC 
RRKKKCVRYI QGEGSCLSPP SSDGSLLDSP PPSPNLLGSP PRDAKSQTEQ TQPLSLSLKP 
DPLAHLSMMP PPPALLLAEA THKASALCPN GALDLPPAAL QPAAPSSSIA QPSTSSLHSH 
SSLAGTQPQP LSLVTKSLE

Genular Protein ID: 3699685505

Symbol: Q6FHW4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6FHW4

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 5 Gene3D 2 IntAct 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SMR 1 SUPFAM 1 VEuPathDB 1 iPTMnet 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 596
  • Mass: 65291
  • Checksum: A022284FEC164B09
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ 
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES 
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI 
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE 
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCRRK KKCVRYIQGE GSCLSPPSSD 
GSLLDSPPPS PNLLGSPPRD AKSQTEQTQP LSLSLKPDPL AHLSMMPPPP ALLLAEATHK 
ASALCPNGAL DLPPAALQPA APSSSIAQPS TSSLHSHSSL AGTQPQPLSL VTKSLE

Genular Protein ID: 2677500817

Symbol: A0A0A0MTL7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MTL7

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 408
  • Mass: 45379
  • Checksum: 3C90E20FE560586F
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTSNK VPVVQHPHHV HPLTPLITYS NEHFTPGNPP PHLPADVDPK TGIPRPPHPP 
DISPYYPLSP GTVGQIPHPL GWLVPQQGQP VYPITTGGFR HPYPTALTVN ASMSRFPPHM 
VPPHHTLHTT GIPHPAIVTP TVKQESSQSD VGSLHSSKHQ DSKKEEEKKK PHIKKPLNAF 
MLYMKEMRAK VVAECTLKES AAINQILGRR WHALSREEQA KYYELARKER QLHMQLYPGW 
SARDNYGKKK KRKRDKQPGE TNGEKKSAFA TYKVKAAASA HPLQMEAY

Genular Protein ID: 2062761866

Symbol: A0A994J711_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A994J711

Database IDs:

ARBA 4 CDD 1 CTD 1 EMBL 4 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 459
  • Mass: 51049
  • Checksum: 91C97625260B64A7
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ 
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES 
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI 
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE 
CFLNPCLSLP PITGEKKSAF ATYKVKAAAS AHPLQMEAY

Genular Protein ID: 3422145039

Symbol: C6ZRJ7_HUMAN

Name: N/A

UniProtKB Accession Codes:

C6ZRJ7

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 476
  • Mass: 53046
  • Checksum: 726564D7AA715AFE
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ 
QGQPVYPITT GGFRHPYPTA LTVNASMSSF LSSRFPPHMV PPHHTLHTTG IPHPAIVTPT 
VKQESSQSDV GSLHSSKHQD SKKEEEKKKP HIKKPLNAFM LYMKEMRAKV VAECTLKESA 
AINQILGRRW HALSREEQAK YYELARKERQ LHMQLYPGWS ARDNYGKKKK RKRDKQPGET 
NEHSECFLNP CLSLPPITDL SAPKKCRARF GLDQQNNWCG PCRCKYSKEV SGTVRA

Genular Protein ID: 4105658634

Symbol: C6ZRK5_HUMAN

Name: N/A

UniProtKB Accession Codes:

C6ZRK5 Q5JRY5

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 1 UCSC 2 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 579
  • Mass: 63409
  • Checksum: 900E2A3AE7F4A2CD
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ 
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES 
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI 
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNDLSA 
PKKCRARFGL DQQNNWCGPC RRKKKCVRYI QGEGSCLSPP SSDGSLLDSP PPSPNLLGSP 
PRDAKSQTEQ TQPLSLSLKP DPLAHLSMMP PPPALLLAEA THKASALCPN GALDLPPAAL 
QPAAPSSSIA QPSTSSLHSH SSLAGTQPQP LSLVTKSLE

Genular Protein ID: 3107675461

Symbol: Q5VVR7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5VVR7 C6ZRJ9

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 455
  • Mass: 50721
  • Checksum: EF7FBE721FB99935
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWQGQP 
VYPITTGGFR HPYPTALTVN ASMSRFPPHM VPPHHTLHTT GIPHPAIVTP TVKQESSQSD 
VGSLHSSKHQ DSKKEEEKKK PHIKKPLNAF MLYMKEMRAK VVAECTLKES AAINQILGRR 
WHALSREEQA KYYELARKER QLHMQLYPGW SARDNYGKKK KRKRDKQPGE TNEHSECFLN 
PCLSLPPITD LSAPKKCRAR FGLDQQNNWC GPCSL

Genular Protein ID: 1451909932

Symbol: C6ZRK2_HUMAN

Name: N/A

UniProtKB Accession Codes:

C6ZRK2

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

Sequence Information:

  • Length: 408
  • Mass: 45407
  • Checksum: 11BF320FE560586C
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTSNK VPVVQHPHHV HPLTPLITYS NEHFTPGNPP PHLPADVDPK TGIPRPPHPP 
DISPYYPLSP GTVGQIPHPL GWLVPQQGQP VYPITTGGFR HPYPTALTVN ASMSRFPPHM 
VPPHHTLHTT GIPHPAIVTP TVKQESSQSD VGSLHSSKHQ DSKKEEEKKK PHIKKPLNAF 
MLYMKEMRAK VVAECTLKES AAINQILGRR WHALSREEQA KYYELARKER QLHMQLYPGW 
SARDNYGKKK KRKRDKRPGE TNGEKKSAFA TYKVKAAASA HPLQMEAY

Genular Protein ID: 888329393

Symbol: C6ZRK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

C6ZRK1

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 19602480

Title: Tissue-specific alternative splicing of TCF7L2.

PubMed ID: 19602480

DOI: 10.1093/hmg/ddp321

Sequence Information:

  • Length: 459
  • Mass: 51049
  • Checksum: DB13162536D1088F
  • Sequence:
    • MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ 
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES 
SQSDVGSLHS SKHQDSQKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI 
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE 
CFLNPCLSLP PITGEKKSAF ATYKVKAAAS AHPLQMEAY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.