Details for: TRIO

Gene ID: 7204

Symbol: TRIO

Ensembl ID: ENSG00000038382

Description: trio Rho guanine nucleotide exchange factor

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 5.57
    Marker Score: 188032
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 4.59
    Marker Score: 15400
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 4.39
    Marker Score: 23589
  • Cell Name: granule cell (CL0000120)
    Fold Change: 4.08
    Marker Score: 30762
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 4.08
    Marker Score: 21400
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 4.05
    Marker Score: 5704
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.93
    Marker Score: 8632
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.74
    Marker Score: 17285
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 3.66
    Marker Score: 3002
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 3.64
    Marker Score: 1751
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 3.64
    Marker Score: 8366
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 3.63
    Marker Score: 3137
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 3.52
    Marker Score: 3118
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.48
    Marker Score: 4333
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 3.46
    Marker Score: 2011
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.38
    Marker Score: 14166
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.28
    Marker Score: 58155
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 3.27
    Marker Score: 73129
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 3.17
    Marker Score: 1763
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 3.14
    Marker Score: 3610
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.12
    Marker Score: 5999
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.06
    Marker Score: 65360
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 3.04
    Marker Score: 12666.5
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 3.04
    Marker Score: 1702
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3
    Marker Score: 1490
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.99
    Marker Score: 873
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.89
    Marker Score: 1727
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 2.89
    Marker Score: 1057
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.88
    Marker Score: 830
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.87
    Marker Score: 57165
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.86
    Marker Score: 908
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 2.81
    Marker Score: 2165
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 2.81
    Marker Score: 1847
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.75
    Marker Score: 870
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.74
    Marker Score: 7823
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.74
    Marker Score: 21012
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.73
    Marker Score: 40881
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 2.73
    Marker Score: 1897
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.69
    Marker Score: 1505
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.66
    Marker Score: 101039
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.6
    Marker Score: 4358
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.58
    Marker Score: 10695
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.54
    Marker Score: 977
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.53
    Marker Score: 1371
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.52
    Marker Score: 1474
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.48
    Marker Score: 1633
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.44
    Marker Score: 90142
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.4
    Marker Score: 2718
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.38
    Marker Score: 998
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.37
    Marker Score: 2256
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.35
    Marker Score: 37714
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 2.34
    Marker Score: 845
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.33
    Marker Score: 9001
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.31
    Marker Score: 7566
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.29
    Marker Score: 3325
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.26
    Marker Score: 1171
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.25
    Marker Score: 2778
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 2.24
    Marker Score: 2797
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.22
    Marker Score: 2982
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.19
    Marker Score: 796
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.17
    Marker Score: 20448
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.15
    Marker Score: 1252
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.14
    Marker Score: 2302
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.11
    Marker Score: 536
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.09
    Marker Score: 2530
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.07
    Marker Score: 127385
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.99
    Marker Score: 1498
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.99
    Marker Score: 20525
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.96
    Marker Score: 740
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.95
    Marker Score: 7943
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.94
    Marker Score: 6894
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.92
    Marker Score: 18209
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.91
    Marker Score: 65008
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.91
    Marker Score: 1004
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.9
    Marker Score: 492
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.89
    Marker Score: 626
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.89
    Marker Score: 6710
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.87
    Marker Score: 16032
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.86
    Marker Score: 584
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.84
    Marker Score: 9039
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 1.82
    Marker Score: 551
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.77
    Marker Score: 484
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.75
    Marker Score: 4372
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.73
    Marker Score: 1502
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.72
    Marker Score: 1838
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.71
    Marker Score: 1886.5
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.69
    Marker Score: 2043
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.68
    Marker Score: 3959
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.64
    Marker Score: 810
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.62
    Marker Score: 2500
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.62
    Marker Score: 521
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.61
    Marker Score: 1223
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.59
    Marker Score: 3796
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.55
    Marker Score: 9988
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.54
    Marker Score: 8286
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.5
    Marker Score: 511
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.5
    Marker Score: 395
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.49
    Marker Score: 2110
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.46
    Marker Score: 541
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.44
    Marker Score: 6204

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key Characteristics:** TRIO is a triple functional domain protein, characterized by its unique structure and Rho GEF activity. Its ability to exchange GTP for GDP on Rho GTPases, such as Rac, Rho, and Cdc42, regulates various signaling pathways involved in cell migration, adhesion, and survival. TRIO's expression is widespread, with significant levels found in neuronal cells, where it is thought to play a role in axon guidance and neuronal projection morphogenesis. In immune cells, TRIO has been implicated in the regulation of cell death signaling, including the activation of JNK pathways. **Pathways and Functions:** TRIO's involvement in various signaling pathways underscores its importance in regulating cellular responses to different stimuli. Some of the key pathways and functions associated with TRIO include: 1. **Rho GTPase Cycle:** TRIO's Rho GEF activity regulates the Rho GTPase cycle, which is involved in cell migration, adhesion, and survival. 2. **Axon Guidance:** TRIO plays a crucial role in axon guidance, a process essential for neuronal development and function. 3. **Cell Death Signaling:** TRIO's activation of JNK pathways has been implicated in cell death signaling, highlighting its potential role in regulating immune responses. 4. **Neuronal Projection Morphogenesis:** TRIO's expression in neuronal cells suggests its involvement in the regulation of neuronal projection morphogenesis. 5. **Immune Cell Functions:** TRIO has been shown to regulate immune cell functions, including the activation of JNK pathways and the regulation of cell death signaling. **Clinical Significance:** The significance of TRIO in various cellular processes has far-reaching implications for the diagnosis and treatment of diseases. Some potential clinical applications of TRIO include: 1. **Neurological Disorders:** TRIO's involvement in axon guidance and neuronal projection morphogenesis makes it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 2. **Immune-Mediated Diseases:** TRIO's role in regulating immune cell functions and cell death signaling makes it a potential target for the treatment of immune-mediated diseases, such as multiple sclerosis and rheumatoid arthritis. 3. **Cancer:** TRIO's involvement in cell migration and adhesion regulation makes it a potential target for the treatment of cancer. In conclusion, TRIO is a multifunctional protein that plays a crucial role in various cellular processes, including axon guidance, cell death signaling, and immune responses. Its widespread expression in different cell types and its involvement in various signaling pathways underscore its significance in both immune and non-immune cell contexts. Further research into TRIO's functions and clinical applications is necessary to fully appreciate its potential as a therapeutic target.

Genular Protein ID: 673225481

Symbol: TRIO_HUMAN

Name: Triple functional domain protein

UniProtKB Accession Codes:

O75962 D3DTD1 Q13458 Q59EQ7 Q6PJC9 Q6ZN05 Q8IWK8

Database IDs:

ABCD 1 AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 8 CTD 1 ChEBI 12 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 DisProt 1 EC 3 EMBL 13 EMDB 1 EPD 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 7 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 22 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 4 PRO 1 PROSITE 7 PROSITE-ProRule 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 8 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 11 RefSeq 2 Rhea 6 SAM 1 SIGNOR 1 SMART 8 SMR 1 STRING 1 SUPFAM 7 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8643598

Title: The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

PubMed ID: 8643598

DOI: 10.1073/pnas.93.11.5466

PubMed ID: 10341202

Title: Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth.

PubMed ID: 10341202

DOI: 10.1242/jcs.112.12.1825

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19846667

Title: Distinct roles for CARMIL isoforms in cell migration.

PubMed ID: 19846667

DOI: 10.1091/mbc.e08-10-1071

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22155786

Title: Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.

PubMed ID: 22155786

DOI: 10.1126/scisignal.2002060

PubMed ID: 22666460

Title: ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells.

PubMed ID: 22666460

DOI: 10.1371/journal.pone.0038130

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26721934

Title: TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.

PubMed ID: 26721934

DOI: 10.1093/hmg/ddv618

PubMed ID: 27418539

Title: Mutations specific to the Rac-GEF domain of TRIO cause intellectual disability and microcephaly.

PubMed ID: 27418539

DOI: 10.1136/jmedgenet-2016-103942

PubMed ID: 9790533

Title: NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio.

PubMed ID: 9790533

DOI: 10.1016/s0092-8674(00)81757-2

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

PubMed ID: 32109419

Title: Opposite modulation of RAC1 by mutations in TRIO is associated with distinct, domain-specific neurodevelopmental disorders.

PubMed ID: 32109419

DOI: 10.1016/j.ajhg.2020.01.018

Sequence Information:

  • Length: 3097
  • Mass: 346900
  • Checksum: EA9236DF88B0EA24
  • Sequence:
    • MSGSSGGAAA PAASSGPAAA ASAAGSGCGG GAGEGAEEAA KDLADIAAFF RSGFRKNDEM 
KAMDVLPILK EKVAYLSGGR DKRGGPILTF PARSNHDRIR QEDLRRLISY LACIPSEEVC 
KRGFTVIVDM RGSKWDSIKP LLKILQESFP CCIHVALIIK PDNFWQKQRT NFGSSKFEFE 
TNMVSLEGLT KVVDPSQLTP EFDGCLEYNH EEWIEIRVAF EDYISNATHM LSRLEELQDI 
LAKKELPQDL EGARNMIEEH SQLKKKVIKA PIEDLDLEGQ KLLQRIQSSE SFPKKNSGSG 
NADLQNLLPK VSTMLDRLHS TRQHLHQMWH VRKLKLDQCF QLRLFEQDAE KMFDWITHNK 
GLFLNSYTEI GTSHPHAMEL QTQHNHFAMN CMNVYVNINR IMSVANRLVE SGHYASQQIR 
QIASQLEQEW KAFAAALDER STLLDMSSIF HQKAEKYMSN VDSWCKACGE VDLPSELQDL 
EDAIHHHQGI YEHITLAYSE VSQDGKSLLD KLQRPLTPGS SDSLTASANY SKAVHHVLDV 
IHEVLHHQRQ LENIWQHRKV RLHQRLQLCV FQQDVQQVLD WIENHGEAFL SKHTGVGKSL 
HRARALQKRH EDFEEVAQNT YTNADKLLEA AEQLAQTGEC DPEEIYQAAH QLEDRIQDFV 
RRVEQRKILL DMSVSFHTHV KELWTWLEEL QKELLDDVYA ESVEAVQDLI KRFGQQQQTT 
LQVTVNVIKE GEDLIQQLRD SAISSNKTPH NSSINHIETV LQQLDEAQSQ MEELFQERKI 
KLELFLQLRI FERDAIDIIS DLESWNDELS QQMNDFDTED LTIAEQRLQH HADKALTMNN 
LTFDVIHQGQ DLLQYVNEVQ ASGVELLCDR DVDMATRVQD LLEFLHEKQQ ELDLAAEQHR 
KHLEQCVQLR HLQAEVKQVL GWIRNGESML NAGLITASSL QEAEQLQREH EQFQHAIEKT 
HQSALQVQQK AEAMLQANHY DMDMIRDCAE KVASHWQQLM LKMEDRLKLV NASVAFYKTS 
EQVCSVLESL EQEYKREEDW CGGADKLGPN SETDHVTPMI SKHLEQKEAF LKACTLARRN 
ADVFLKYLHR NSVNMPGMVT HIKAPEQQVK NILNELFQRE NRVLHYWTMR KRRLDQCQQY 
VVFERSAKQA LEWIHDNGEF YLSTHTSTGS SIQHTQELLK EHEEFQITAK QTKERVKLLI 
QLADGFCEKG HAHAAEIKKC VTAVDKRYRD FSLRMEKYRT SLEKALGISS DSNKSSKSLQ 
LDIIPASIPG SEVKLRDAAH ELNEEKRKSA RRKEFIMAEL IQTEKAYVRD LRECMDTYLW 
EMTSGVEEIP PGIVNKELII FGNMQEIYEF HNNIFLKELE KYEQLPEDVG HCFVTWADKF 
QMYVTYCKNK PDSTQLILEH AGSYFDEIQQ RHGLANSISS YLIKPVQRIT KYQLLLKELL 
TCCEEGKGEI KDGLEVMLSV PKRANDAMHL SMLEGFDENI ESQGELILQE SFQVWDPKTL 
IRKGRERHLF LFEMSLVFSK EVKDSSGRSK YLYKSKLFTS ELGVTEHVEG DPCKFALWVG 
RTPTSDNKIV LKASSIENKQ DWIKHIREVI QERTIHLKGA LKEPIHIPKT APATRQKGRR 
DGEDLDSQGD GSSQPDTISI ASRTSQNTLD SDKLSGGCEL TVVIHDFTAC NSNELTIRRG 
QTVEVLERPH DKPDWCLVRT TDRSPAAEGL VPCGSLCIAH SRSSMEMEGI FNHKDSLSVS 
SNDASPPASV ASLQPHMIGA QSSPGPKRPG NTLRKWLTSP VRRLSSGKAD GHVKKLAHKH 
KKSREVRKSA DAGSQKDSDD SAATPQDETV EERGRNEGLS SGTLSKSSSS GMQSCGEEEG 
EEGADAVPLP PPMAIQQHSL LQPDSQDDKA SSRLLVRPTS SETPSAAELV SAIEELVKSK 
MALEDRPSSL LVDQGDSSSP SFNPSDNSLL SSSSPIDEME ERKSSSLKRR HYVLQELVET 
ERDYVRDLGY VVEGYMALMK EDGVPDDMKG KDKIVFGNIH QIYDWHRDFF LGELEKCLED 
PEKLGSLFVK HERRLHMYIA YCQNKPKSEH IVSEYIDTFF EDLKQRLGHR LQLTDLLIKP 
VQRIMKYQLL LKDFLKYSKK ASLDTSELER AVEVMCIVPR RCNDMMNVGR LQGFDGKIVA 
QGKLLLQDTF LVTDQDAGLL PRCRERRIFL FEQIVIFSEP LDKKKGFSMP GFLFKNSIKV 
SCLCLEENVE NDPCKFALTS RTGDVVETFI LHSSSPSVRQ TWIHEINQIL ENQRNFLNAL 
TSPIEYQRNH SGGGGGGGSG GSGGGGGSGG GGAPSGGSGH SGGPSSCGGA PSTSRSRPSR 
IPQPVRHHPP VLVSSAASSQ AEADKMSGTS TPGPSLPPPG AAPEAGPSAP SRRPPGADAE 
GSEREAEPIP KMKVLESPRK GAANASGSSP DAPAKDARAS LGTLPLGKPR AGAASPLNSP 
LSSAVPSLGK EPFPPSSPLQ KGGSFWSSIP ASPASRPGSF TFPGDSDSLQ RQTPRHAAPG 
KDTDRMSTCS SASEQSVQST QSNGSESSSS SNISTMLVTH DYTAVKEDEI NVYQGEVVQI 
LASNQQNMFL VFRAATDQCP AAEGWIPGFV LGHTSAVIVE NPDGTLKKST SWHTALRLRK 
KSEKKDKDGK REGKLENGYR KSREGLSNKV SVKLLNPNYI YDVPPEFVIP LSEVTCETGE 
TVVLRCRVCG RPKASITWKG PEHNTLNNDG HYSISYSDLG EATLKIVGVT TEDDGIYTCI 
AVNDMGSASS SASLRVLGPG MDGIMVTWKD NFDSFYSEVA ELGRGRFSVV KKCDQKGTKR 
AVATKFVNKK LMKRDQVTHE LGILQSLQHP LLVGLLDTFE TPTSYILVLE MADQGRLLDC 
VVRWGSLTEG KIRAHLGEVL EAVRYLHNCR IAHLDLKPEN ILVDESLAKP TIKLADFGDA 
VQLNTTYYIH QLLGNPEFAA PEIILGNPVS LTSDTWSVGV LTYVLLSGVS PFLDDSVEET 
CLNICRLDFS FPDDYFKGVS QKAKEFVCFL LQEDPAKRPS AALALQEQWL QAGNGRSTGV 
LDTSRLTSFI ERRKHQNDVR PIRSIKNFLQ SRLLPRV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.