Details for: MEIS2
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 5.91
Marker Score: 5,242 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 5.03
Marker Score: 3,783 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 4.7
Marker Score: 83,432 - Cell Name: endocrine cell (CL0000163)
Fold Change: 4.48
Marker Score: 2,320 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 4.4
Marker Score: 3,058 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: 4.35
Marker Score: 97,311 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 3.84
Marker Score: 5,170 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 3.8
Marker Score: 7,308 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 3.77
Marker Score: 4,559 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 3.65
Marker Score: 5,138 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 3.6
Marker Score: 2,372 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 3.39
Marker Score: 14,176 - Cell Name: mesodermal cell (CL0000222)
Fold Change: 3.32
Marker Score: 43,778 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 3.11
Marker Score: 66,400 - Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 3.09
Marker Score: 2,944 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 2.93
Marker Score: 761 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 2.88
Marker Score: 25,297 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 2.79
Marker Score: 950 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 2.75
Marker Score: 1,609 - Cell Name: fat cell (CL0000136)
Fold Change: 2.73
Marker Score: 1,525 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 2.6
Marker Score: 820 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 2.59
Marker Score: 832 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 2.53
Marker Score: 738 - Cell Name: contractile cell (CL0000183)
Fold Change: 2.52
Marker Score: 1,368 - Cell Name: peritubular capillary endothelial cell (CL1001033)
Fold Change: 2.48
Marker Score: 576 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.39
Marker Score: 81,313 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 2.38
Marker Score: 5,422 - Cell Name: smooth muscle cell of large intestine (CL1000279)
Fold Change: 2.32
Marker Score: 878 - Cell Name: enteric smooth muscle cell (CL0002504)
Fold Change: 2.26
Marker Score: 5,322 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 2.22
Marker Score: 4,636 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 2.21
Marker Score: 2,368 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 2.19
Marker Score: 3,724 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: 2.16
Marker Score: 20,357 - Cell Name: endocardial cell (CL0002350)
Fold Change: 2.16
Marker Score: 1,222 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 2.14
Marker Score: 5,122 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 2.07
Marker Score: 7,661 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.06
Marker Score: 2,336 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 2.04
Marker Score: 1,676 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 2.04
Marker Score: 588 - Cell Name: smooth muscle cell of prostate (CL1000487)
Fold Change: 2
Marker Score: 510 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.98
Marker Score: 683 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 1.97
Marker Score: 4,012 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 1.97
Marker Score: 683 - Cell Name: PP cell (CL0000696)
Fold Change: 1.96
Marker Score: 441 - Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 1.91
Marker Score: 3,817 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.87
Marker Score: 17,801 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.85
Marker Score: 866 - Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 1.84
Marker Score: 2,668 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 1.83
Marker Score: 2,819 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.82
Marker Score: 2,274 - Cell Name: astrocyte (CL0000127)
Fold Change: 1.82
Marker Score: 1,579 - Cell Name: glomerular endothelial cell (CL0002188)
Fold Change: 1.82
Marker Score: 461 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 1.81
Marker Score: 759 - Cell Name: alveolar type 2 fibroblast cell (CL4028006)
Fold Change: 1.81
Marker Score: 1,006 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 1.8
Marker Score: 1,045 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 1.79
Marker Score: 562 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.78
Marker Score: 2,914 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: 1.74
Marker Score: 6,198 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.71
Marker Score: 5,602 - Cell Name: Unknown (CL0002371)
Fold Change: 1.7
Marker Score: 1,801 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 1.69
Marker Score: 464 - Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 1.64
Marker Score: 1,408 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 1.61
Marker Score: 2,490 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.61
Marker Score: 11,994 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.58
Marker Score: 1,147 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.56
Marker Score: 6,495 - Cell Name: serous secreting cell (CL0000313)
Fold Change: 1.56
Marker Score: 621 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.54
Marker Score: 1,598 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 1.51
Marker Score: 549 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 1.51
Marker Score: 1,287 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 1.48
Marker Score: 842 - Cell Name: mural cell (CL0008034)
Fold Change: 1.46
Marker Score: 167,276 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 1.45
Marker Score: 1,791 - Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 1.43
Marker Score: 1,017 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.41
Marker Score: 529 - Cell Name: germ cell (CL0000586)
Fold Change: 1.34
Marker Score: 2,345 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 1.33
Marker Score: 6,978 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.31
Marker Score: 1,384 - Cell Name: mesothelial cell (CL0000077)
Fold Change: 1.31
Marker Score: 528 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.31
Marker Score: 20,499 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: 1.3
Marker Score: 632 - Cell Name: CNS interneuron (CL0000402)
Fold Change: 1.29
Marker Score: 620 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 1.28
Marker Score: 517 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 1.28
Marker Score: 1,203 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 1.28
Marker Score: 404 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.28
Marker Score: 380 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 1.28
Marker Score: 8,295 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.27
Marker Score: 316 - Cell Name: myofibroblast cell (CL0000186)
Fold Change: 1.27
Marker Score: 1,572 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 1.27
Marker Score: 712 - Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
Fold Change: 1.26
Marker Score: 331 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 1.22
Marker Score: 268 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.2
Marker Score: 10,278 - Cell Name: acinar cell (CL0000622)
Fold Change: 1.16
Marker Score: 817 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 1.15
Marker Score: 445 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 1.14
Marker Score: 431 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: 1.12
Marker Score: 468 - Cell Name: supporting cell (CL0000630)
Fold Change: 1.12
Marker Score: 2,111 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 1.12
Marker Score: 1,880 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.11
Marker Score: 3,033
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3890267073
Symbol: MEIS2_HUMAN
Name: Homeobox protein Meis2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10764806
Title: Three-amino acid extension loop homeodomain proteins Meis2 and TGIF differentially regulate transcription.
PubMed ID: 10764806
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9383298
Title: Chromosomal mapping to 15q14 and expression analysis of the human MEIS2 homeobox gene.
PubMed ID: 9383298
PubMed ID: 11279116
Title: DNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complex.
PubMed ID: 11279116
PubMed ID: 20523026
Title: Spatiotemporal distribution of PAX6 and MEIS2 expression and total cell numbers in the ganglionic eminence in the early developing human forebrain.
PubMed ID: 20523026
DOI: 10.1159/000297602
PubMed ID: 20553494
Title: An autoinhibitory effect of the homothorax domain of Meis2.
PubMed ID: 20553494
PubMed ID: 19559479
Title: MEIS proteins as partners of the TLX1/HOX11 oncoprotein.
PubMed ID: 19559479
PubMed ID: 21746878
Title: Cooperative transcriptional activation by Klf4, Meis2, and Pbx1.
PubMed ID: 21746878
DOI: 10.1128/mcb.01456-10
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24678003
Title: Haploinsufficiency of MEIS2 is associated with orofacial clefting and learning disability.
PubMed ID: 24678003
DOI: 10.1002/ajmg.a.36498
PubMed ID: 26550823
Title: DNA-dependent formation of transcription factor pairs alters their binding specificity.
PubMed ID: 26550823
DOI: 10.1038/nature15518
PubMed ID: 25712757
Title: MEIS2 involvement in cardiac development, cleft palate, and intellectual disability.
PubMed ID: 25712757
DOI: 10.1002/ajmg.a.36989
PubMed ID: 27225850
Title: De novo MEIS2 mutation causes syndromic developmental delay with persistent gastro-esophageal reflux.
PubMed ID: 27225850
DOI: 10.1038/jhg.2016.54
Sequence Information:
- Length: 477
- Mass: 51790
- Checksum: 94EBD0801A312B24
- Sequence:
MAQRYDELPH YGGMDGVGVP ASMYGDPHAP RPIPPVHHLN HGPPLHATQH YGAHAPHPNV MPASMGSAVN DALKRDKDAI YGHPLFPLLA LVFEKCELAT CTPREPGVAG GDVCSSDSFN EDIAVFAKQV RAEKPLFSSN PELDNLMIQA IQVLRFHLLE LEKVHELCDN FCHRYISCLK GKMPIDLVID ERDGSSKSDH EELSGSSTNL ADHNPSSWRD HDDATSTHSA GTPGPSSGGH ASQSGDNSSE QGDGLDNSVA SPGTGDDDDP DKDKKRQKKR GIFPKVATNI MRAWLFQHLT HPYPSEEQKK QLAQDTGLTI LQVNNWFINA RRRIVQPMID QSNRAGFLLD PSVSQGAAYS PEGQPMGSFV LDGQQHMGIR PAGLQSMPGD YVSQGGPMGM SMAQPSYTPP QMTPHPTQLR HGPPMHSYLP SHPHHPAMMM HGGPPTHPGM TMSAQSPTML NSVDPNVGGQ VMDIHAQ
Genular Protein ID: 1860660238
Symbol: B7Z6F6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 457
- Mass: 49541
- Checksum: 465000408DFF504B
- Sequence:
MDGVGVPASM YGDPHAPRPI PPVHHLNHGP PLHATQHYGA HAPHPNVMPA SMGSAVNDAL KRDKDAIYGH PLFPLLALVF EKCKLATCTP REPGVAGGDV CSSDSFNEDI AVFAKQVRAE KPLFSSNPEL DNLMIQAIQV LRFHLLELEK VHELCDNFCH RYISCLKGKM PIDLVIDERD GSSKSDHEEL SGSSTNLADH NPSSWRDHDD ATSTHSAGTP GPSSGGHASQ SGDNSSEQGD GLDNSVASPG TGDDDDPDKD KKRQKKRGIF PKVATNIMRA WLFQHLTHPY PSEEQKKQLA QDTGLTILQV NNWFINARRR IVQPMIDQSN RAVSQGAAYS PEGQPMGSFV LDGQQHMGIR PAGLQSMPGD YVSQGGPMGM SMAQPSYTPP QMTPHPTQLR HGPPMHSYLP SHPHHPAMMM HGGPPTHPGM TMSAQSPTML NSVDPNVGGQ VMDIHAQ
Genular Protein ID: 2351306299
Symbol: B3KPD8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 388
- Mass: 42256
- Checksum: 59B5404A0DC5B533
- Sequence:
MDGVGVPASM YGDPHAPRPI PPVHHLNHGP PLHATQHYGA HAPHPNVMPA SMGSAVNDAL KRDKDAIYGH PLFPLLALVF EKCEPATCTP REPGVAGGDV CSSDSFNEDI AVFAKQVRAE KPLFSSNPEL DNLMIQAIQV LRFHLLELEK VHELCDNFCH RYISCLKGKM PIDLVIDERD GSSKSDHEEL SGSSTNLADH NPSSWRDHDD ATSTHSAGTP GPSSGGHASQ SGDNSSEQGD GLDNSVASPG TGDDDDPDKD KKRQKKRGIF PKVATNIMRA WLFQHLTHPY PSEEQKKQLA QDTGLTILQV NNWFINARRR IVQPMIDQSN RAGFLLDPSV SQGAAYSPEG QPMGSFVLDG QQHMGIRPAG PMSGMGMNMG MDGQWHYM
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.