Details for: MAP3K5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 301.7772
Cell Significance Index: -46.9400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 186.2457
Cell Significance Index: -47.2400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 94.2260
Cell Significance Index: -38.2800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 87.9691
Cell Significance Index: -45.2500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 40.1365
Cell Significance Index: -38.3200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 38.7037
Cell Significance Index: -47.7200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 20.6206
Cell Significance Index: -45.1300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.4868
Cell Significance Index: -53.7100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 12.1387
Cell Significance Index: -47.9000 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 12.0118
Cell Significance Index: 106.6300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 9.9839
Cell Significance Index: 267.5200 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 7.8043
Cell Significance Index: 48.1500 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 5.1368
Cell Significance Index: 71.8300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.9406
Cell Significance Index: 149.2200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 3.4341
Cell Significance Index: 151.9000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 2.9855
Cell Significance Index: 229.1100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.5540
Cell Significance Index: 512.3200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.9883
Cell Significance Index: 56.7400 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.9247
Cell Significance Index: 129.4200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 1.8731
Cell Significance Index: 32.1000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 1.8076
Cell Significance Index: 35.2800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.3790
Cell Significance Index: 494.6200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 1.3397
Cell Significance Index: 37.4400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.2492
Cell Significance Index: 64.8900 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: 1.2412
Cell Significance Index: 15.6300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1439
Cell Significance Index: 113.1600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.9241
Cell Significance Index: 23.1000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6362
Cell Significance Index: 1197.8800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6288
Cell Significance Index: 102.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.6273
Cell Significance Index: 113.0800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6034
Cell Significance Index: 544.8600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5497
Cell Significance Index: 59.7900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.5373
Cell Significance Index: 11.4900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5360
Cell Significance Index: 370.7200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5231
Cell Significance Index: 64.3200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.4839
Cell Significance Index: 307.3300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.4642
Cell Significance Index: 210.7000 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.3851
Cell Significance Index: 5.5300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.3259
Cell Significance Index: 5.4900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2391
Cell Significance Index: 32.8400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2095
Cell Significance Index: 114.3900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1964
Cell Significance Index: 37.3700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1572
Cell Significance Index: 10.8700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1374
Cell Significance Index: 3.9600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1363
Cell Significance Index: 23.2700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1293
Cell Significance Index: 5.8600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0689
Cell Significance Index: 30.4500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0360
Cell Significance Index: 2.3300 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.0231
Cell Significance Index: 0.4000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0062
Cell Significance Index: -9.5700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0173
Cell Significance Index: -31.9400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0317
Cell Significance Index: -23.4900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0330
Cell Significance Index: -44.8900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0425
Cell Significance Index: -26.5300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0498
Cell Significance Index: -36.5300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0528
Cell Significance Index: -39.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0556
Cell Significance Index: -31.3600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0954
Cell Significance Index: -18.9400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0960
Cell Significance Index: -2.0800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0969
Cell Significance Index: -10.0900 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: -0.1080
Cell Significance Index: -0.4700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1166
Cell Significance Index: -5.4800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1187
Cell Significance Index: -17.2600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1408
Cell Significance Index: -40.5200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1506
Cell Significance Index: -31.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2093
Cell Significance Index: -21.3800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2271
Cell Significance Index: -26.4700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2655
Cell Significance Index: -2.1700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2753
Cell Significance Index: -2.5400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2953
Cell Significance Index: -38.1500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2981
Cell Significance Index: -6.4400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3457
Cell Significance Index: -40.7700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3626
Cell Significance Index: -46.4800 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.3977
Cell Significance Index: -6.0500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3994
Cell Significance Index: -45.7600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4040
Cell Significance Index: -24.8300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.4180
Cell Significance Index: -6.1700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4262
Cell Significance Index: -26.1300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4473
Cell Significance Index: -51.0600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4821
Cell Significance Index: -10.0000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5034
Cell Significance Index: -37.5200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5111
Cell Significance Index: -23.8300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.5247
Cell Significance Index: -7.0000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5283
Cell Significance Index: -41.8400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5348
Cell Significance Index: -11.3900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5408
Cell Significance Index: -17.3200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.5437
Cell Significance Index: -14.8000 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5492
Cell Significance Index: -10.8600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.5649
Cell Significance Index: -8.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.6234
Cell Significance Index: -44.0900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6452
Cell Significance Index: -20.5500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.6672
Cell Significance Index: -9.5500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.6988
Cell Significance Index: -36.4000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7134
Cell Significance Index: -37.4600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.7242
Cell Significance Index: -20.7600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.7453
Cell Significance Index: -41.8200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.7574
Cell Significance Index: -16.0800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.7715
Cell Significance Index: -25.2600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.7739
Cell Significance Index: -18.5600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.8423
Cell Significance Index: -53.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 719269440
Symbol: M3K5_HUMAN
Name: Mitogen-activated protein kinase kinase kinase 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8940179
Title: Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase.
PubMed ID: 8940179
PubMed ID: 8974401
Title: Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways.
PubMed ID: 8974401
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9564042
Title: Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.
PubMed ID: 9564042
PubMed ID: 9774977
Title: ASK1 is essential for JNK/SAPK activation by TRAF2.
PubMed ID: 9774977
PubMed ID: 9743501
Title: Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx.
PubMed ID: 9743501
PubMed ID: 10411906
Title: Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins.
PubMed ID: 10411906
PubMed ID: 10849426
Title: Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation.
PubMed ID: 10849426
PubMed ID: 10688666
Title: Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.
PubMed ID: 10688666
PubMed ID: 11090355
Title: Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.
PubMed ID: 11090355
PubMed ID: 11689443
Title: Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress.
PubMed ID: 11689443
PubMed ID: 11029458
Title: Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation.
PubMed ID: 11029458
PubMed ID: 11154276
Title: Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1.
PubMed ID: 11154276
PubMed ID: 11298454
Title: HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.
PubMed ID: 11298454
DOI: 10.1038/35071111
PubMed ID: 11427728
Title: Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism.
PubMed ID: 11427728
PubMed ID: 14749717
Title: Involvement of ASK1 in Ca2+-induced p38 MAP kinase activation.
PubMed ID: 14749717
PubMed ID: 11920685
Title: Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer.
PubMed ID: 11920685
DOI: 10.1002/jcp.10080
PubMed ID: 12556535
Title: Type 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1).
PubMed ID: 12556535
PubMed ID: 12697749
Title: AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance.
PubMed ID: 12697749
PubMed ID: 27825085
PubMed ID: 12813029
Title: AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3.
PubMed ID: 12813029
DOI: 10.1172/jci17790
PubMed ID: 15023544
Title: Interaction of apoptosis signal-regulating kinase 1 with isoforms of 14-3-3 proteins.
PubMed ID: 15023544
PubMed ID: 14688258
Title: Activation of apoptosis signal-regulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation.
PubMed ID: 14688258
PubMed ID: 15310755
Title: AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation.
PubMed ID: 15310755
PubMed ID: 15094778
Title: Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034.
PubMed ID: 15094778
PubMed ID: 16038411
Title: C-terminus of heat shock protein 70-interacting protein facilitates degradation of apoptosis signal-regulating kinase 1 and inhibits apoptosis signal-regulating kinase 1-dependent apoptosis.
PubMed ID: 16038411
DOI: 10.1379/csc-90r.1
PubMed ID: 15701637
Title: Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation.
PubMed ID: 15701637
PubMed ID: 16129676
Title: Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death.
PubMed ID: 16129676
PubMed ID: 16407264
Title: SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation.
PubMed ID: 16407264
PubMed ID: 17456047
Title: Regulation of apoptosis signal-regulating kinase 1 by protein phosphatase 2Cepsilon.
PubMed ID: 17456047
DOI: 10.1042/bj20070231
PubMed ID: 17210579
Title: Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1.
PubMed ID: 17210579
PubMed ID: 17220297
Title: Tumor necrosis factor receptor 2 signaling induces selective c-IAP1-dependent ASK1 ubiquitination and terminates mitogen-activated protein kinase signaling.
PubMed ID: 17220297
PubMed ID: 17389591
Title: RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation.
PubMed ID: 17389591
PubMed ID: 17724081
Title: Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1.
PubMed ID: 17724081
DOI: 10.1128/mcb.00227-07
PubMed ID: 18408005
Title: The beta-arrestin-2 scaffold protein promotes c-Jun N-terminal kinase-3 activation by binding to its nonconserved N terminus.
PubMed ID: 18408005
PubMed ID: 18948261
Title: Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylation.
PubMed ID: 18948261
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19749799
Title: PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis.
PubMed ID: 19749799
DOI: 10.1038/onc.2009.276
PubMed ID: 19590015
Title: Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1.
PubMed ID: 19590015
PubMed ID: 17883330
Title: Apoptosis signal-regulating kinase 1 in stress and immune response.
PubMed ID: 17883330
PubMed ID: 19389260
Title: The roles of ASK family proteins in stress responses and diseases.
PubMed ID: 19389260
PubMed ID: 20358250
Title: Positive regulation of apoptosis signal-regulating kinase 1 by dual-specificity phosphatase 13A.
PubMed ID: 20358250
PubMed ID: 22095282
Title: Arginine methylation-dependent regulation of ASK1 signaling by PRMT1.
PubMed ID: 22095282
DOI: 10.1038/cdd.2011.168
PubMed ID: 23102700
Title: The Kelch repeat protein KLHDC10 regulates oxidative stress-induced ASK1 activation by suppressing PP5.
PubMed ID: 23102700
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24448648
Title: Roquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responses.
PubMed ID: 24448648
PubMed ID: 26095851
Title: Cyclophilin A regulates JNK/p38-MAPK signaling through its physical interaction with ASK1.
PubMed ID: 26095851
PubMed ID: 29186683
Title: TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.
PubMed ID: 29186683
PubMed ID: 17937911
Title: Structural and functional characterization of the human protein kinase ASK1.
PubMed ID: 17937911
PubMed ID: 17344846
Title: Patterns of somatic mutation in human cancer genomes.
PubMed ID: 17344846
DOI: 10.1038/nature05610
Sequence Information:
- Length: 1374
- Mass: 154537
- Checksum: 265BDC65968AF985
- Sequence:
MSTEADEGIT FSVPPFAPSG FCTIPEGGIC RRGGAAAVGE GEEHQLPPPP PGSFWNVESA AAPGIGCPAA TSSSSATRGR GSSVGGGSRR TTVAYVINEA SQGQLVVAES EALQSLREAC ETVGATLETL HFGKLDFGET TVLDRFYNAD IAVVEMSDAF RQPSLFYHLG VRESFSMANN IILYCDTNSD SLQSLKEIIC QKNTMCTGNY TFVPYMITPH NKVYCCDSSF MKGLTELMQP NFELLLGPIC LPLVDRFIQL LKVAQASSSQ YFRESILNDI RKARNLYTGK ELAAELARIR QRVDNIEVLT ADIVINLLLS YRDIQDYDSI VKLVETLEKL PTFDLASHHH VKFHYAFALN RRNLPGDRAK ALDIMIPMVQ SEGQVASDMY CLVGRIYKDM FLDSNFTDTE SRDHGASWFK KAFESEPTLQ SGINYAVLLL AAGHQFESSF ELRKVGVKLS SLLGKKGNLE KLQSYWEVGF FLGASVLAND HMRVIQASEK LFKLKTPAWY LKSIVETILI YKHFVKLTTE QPVAKQELVD FWMDFLVEAT KTDVTVVRFP VLILEPTKIY QPSYLSINNE VEEKTISIWH VLPDDKKGIH EWNFSASSVR GVSISKFEER CCFLYVLHNS DDFQIYFCTE LHCKKFFEMV NTITEEKGRS TEEGDCESDL LEYDYEYDEN GDRVVLGKGT YGIVYAGRDL SNQVRIAIKE IPERDSRYSQ PLHEEIALHK HLKHKNIVQY LGSFSENGFI KIFMEQVPGG SLSALLRSKW GPLKDNEQTI GFYTKQILEG LKYLHDNQIV HRDIKGDNVL INTYSGVLKI SDFGTSKRLA GINPCTETFT GTLQYMAPEI IDKGPRGYGK AADIWSLGCT IIEMATGKPP FYELGEPQAA MFKVGMFKVH PEIPESMSAE AKAFILKCFE PDPDKRACAN DLLVDEFLKV SSKKKKTQPK LSALSAGSNE YLRSISLPVP VLVEDTSSSS EYGSVSPDTE LKVDPFSFKT RAKSCGERDV KGIRTLFLGI PDENFEDHSA PPSPEEKDSG FFMLRKDSER RATLHRILTE DQDKIVRNLM ESLAQGAEEP KLKWEHITTL IASLREFVRS TDRKIIATTL SKLKLELDFD SHGISQVQVV LFGFQDAVNK VLRNHNIKPH WMFALDSIIR KAVQTAITIL VPELRPHFSL ASESDTADQE DLDVEDDHEE QPSNQTVRRP QAVIEDAVAT SGVSTLSSTV SHDSQSAHRS LNVQLGRMKI ETNRLLEELV RKEKELQALL HRAIEEKDQE IKHLKLKSQP IEIPELPVFH LNSSGTNTED SELTDWLRVN GADEDTISRF LAEDYTLLDV LYYVTRDDLK CLRLRGGMLC TLWKAIIDFR NKQT
Genular Protein ID: 2244526037
Symbol: A0A8V8TMH5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 1483
- Mass: 165913
- Checksum: F215D01E10E7D228
- Sequence:
MKASCRLRGR RVLSAAAAAV PGRRLGSQPA RKRASGAATE APRRSEPPPG SGVPSGERAP ERRRRRGGEG AARDGSCLAR RARSSPELWL ARRCGWAGDA AAVAARPGEM STEADEGITF SVPPFAPSGF CTIPEGGICR RGGAAAVGEG EEHQLPPPPP GSFWNVESAA APGIGCPAAT SSSSATRGRG SSVGGGSRRT TVAYVINEAS QGQLVVAESE ALQSLREACE TVGATLETLH FGKLDFGETT VLDRFYNADI AVVEMSDAFR QPSLFYHLGV RESFSMANNI ILYCDTNSDS LQSLKEIICQ KNTMCTGNYT FVPYMITPHN KVYCCDSSFM KGLTELMQPN FELLLGPICL PLVDRFIQLL KVAQASSSQY FRESILNDIR KARNLYTGKE LAAELARIRQ RVDNIEVLTA DIVINLLLSY RDIQDYDSIV KLVETLEKLP TFDLASHHHV KFHYAFALNR RNLPGDRAKA LDIMIPMVQS EGQVASDMYC LVGRIYKDMF LDSNFTDTES RDHGASWFKK AFESEPTLQS GINYAVLLLA AGHQFESSFE LRKVGVKLSS LLGKKGNLEK LQSYWEVGFF LGASVLANDH MRVIQASEKL FKLKTPAWYL KSIVETILIY KHFVKLTTEQ PVAKQELVDF WMDFLVEATK TDVTVVRFPV LILEPTKIYQ PSYLSINNEV EEKTISIWHV LPDDKKGIHE WNFSASSVRG VSISKFEERC CFLYVLHNSD DFQIYFCTEL HCKKFFEMVN TITEEKGRST EEGDCESDLL EYDYEYDENG DRVVLGKGTY GIVYAGRDLS NQVRIAIKEI PERDSRYSQP LHEEIALHKH LKHKNIVQYL GSFSENGFIK IFMEQVPGGS LSALLRSKWG PLKDNEQTIG FYTKQILEGL KYLHDNQIVH RDIKGDNVLI NTYSGVLKIS DFGTSKRLAG INPCTETFTG TLQYMAPEII DKGPRGYGKA ADIWSLGCTI IEMATGKPPF YELGEPQAAM FKVGMFKVHP EIPESMSAEA KAFILKCFEP DPDKRACAND LLVDEFLKVS SKKKKTQPKL SALSAGSNEY LRSISLPVPV LVEDTSSSSE YGSVSPDTEL KVDPFSFKTR AKSCGERDVK GIRTLFLGIP DENFEDHSAP PSPEEKDSGF FMLRKDSERR ATLHRILTED QDKIVRNLME SLAQGAEEPK LKWEHITTLI ASLREFVRST DRKIIATTLS KLKLELDFDS HGISQVQVVL FGFQDAVNKV LRNHNIKPHW MFALDSIIRK AVQTAITILV PELRPHFSLA SESDTADQED LDVEDDHEEQ PSNQTVRRPQ AVIEDAVATS GVSTLSSTVS HDSQSAHRSL NVQLGRMKIE TNRLLEELVR KEKELQALLH RAIEEKDQEI KHLKLKSQPI EIPELPVFHL NSSGTNTEDS ELTDWLRVNG ADEDTISRFL AEDYTLLDVL YYVTRDDLKC LRLRGGMLCT LWKAIIDFRN KQT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.