Details for: NCAM1

Gene ID: 4684

Symbol: NCAM1

Ensembl ID: ENSG00000149294

Description: neural cell adhesion molecule 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 744.5423
    Cell Significance Index: -115.8100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 461.5141
    Cell Significance Index: -117.0600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 283.8775
    Cell Significance Index: -134.0300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 238.3774
    Cell Significance Index: -96.8400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 93.9206
    Cell Significance Index: -115.8000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 29.6347
    Cell Significance Index: -116.9400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 11.2669
    Cell Significance Index: 632.2400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 9.4285
    Cell Significance Index: 206.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 6.5072
    Cell Significance Index: 156.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 6.4399
    Cell Significance Index: 395.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 5.5060
    Cell Significance Index: 422.5300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.1349
    Cell Significance Index: 1841.8100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.5564
    Cell Significance Index: 157.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.3825
    Cell Significance Index: 128.0900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.3550
    Cell Significance Index: 673.0000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 3.2666
    Cell Significance Index: 219.6500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.1078
    Cell Significance Index: 2149.4800
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 2.7811
    Cell Significance Index: 28.9700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.1646
    Cell Significance Index: 61.7700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.6596
    Cell Significance Index: 75.2300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 1.5633
    Cell Significance Index: 21.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.4674
    Cell Significance Index: 2259.0400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.3503
    Cell Significance Index: 2490.2700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.0736
    Cell Significance Index: 1459.7900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 1.0136
    Cell Significance Index: 53.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9679
    Cell Significance Index: 24.8800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8808
    Cell Significance Index: 795.3200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.8684
    Cell Significance Index: 12.8200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.8374
    Cell Significance Index: 14.3500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.7854
    Cell Significance Index: 24.8400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4071
    Cell Significance Index: 25.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2599
    Cell Significance Index: 25.7100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1692
    Cell Significance Index: 107.4500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1315
    Cell Significance Index: 71.7900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1277
    Cell Significance Index: 240.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1109
    Cell Significance Index: 21.1000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0060
    Cell Significance Index: -0.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0726
    Cell Significance Index: -53.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0873
    Cell Significance Index: -14.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0989
    Cell Significance Index: -61.7600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1518
    Cell Significance Index: -111.3200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1622
    Cell Significance Index: -91.4600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1796
    Cell Significance Index: -135.9600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2100
    Cell Significance Index: -95.3300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.2483
    Cell Significance Index: -109.7900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3136
    Cell Significance Index: -7.8400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3256
    Cell Significance Index: -68.5700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3606
    Cell Significance Index: -10.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4349
    Cell Significance Index: -125.1200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4951
    Cell Significance Index: -71.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.5025
    Cell Significance Index: -90.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5175
    Cell Significance Index: -59.2900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.5255
    Cell Significance Index: -104.2900
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.5528
    Cell Significance Index: -8.4100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.5585
    Cell Significance Index: -4.6100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5682
    Cell Significance Index: -7.0900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.6074
    Cell Significance Index: -66.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.6749
    Cell Significance Index: -115.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.7055
    Cell Significance Index: -96.8900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7404
    Cell Significance Index: -14.6400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.7655
    Cell Significance Index: -8.3400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7673
    Cell Significance Index: -79.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.7999
    Cell Significance Index: -98.3600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.8837
    Cell Significance Index: -10.3100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.9144
    Cell Significance Index: -10.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.9387
    Cell Significance Index: -120.3400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.9823
    Cell Significance Index: -126.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.0470
    Cell Significance Index: -106.9600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.0817
    Cell Significance Index: -123.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.0965
    Cell Significance Index: -129.3100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.1037
    Cell Significance Index: -13.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.1463
    Cell Significance Index: -133.5900
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -1.2517
    Cell Significance Index: -9.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.2534
    Cell Significance Index: -86.6800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -1.2731
    Cell Significance Index: -13.6500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -1.3523
    Cell Significance Index: -17.3400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.3654
    Cell Significance Index: -17.2300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3718
    Cell Significance Index: -47.6700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.3887
    Cell Significance Index: -27.8800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.4771
    Cell Significance Index: -48.3600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.5348
    Cell Significance Index: -48.8800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.5756
    Cell Significance Index: -33.4400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.6165
    Cell Significance Index: -20.0500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.6344
    Cell Significance Index: -28.2600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.6414
    Cell Significance Index: -122.3300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.7581
    Cell Significance Index: -107.7900
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.7892
    Cell Significance Index: -16.9600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -1.8027
    Cell Significance Index: -50.3800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.8041
    Cell Significance Index: -108.3100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -1.8044
    Cell Significance Index: -23.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.8470
    Cell Significance Index: -96.2100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.9671
    Cell Significance Index: -126.9100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -2.0150
    Cell Significance Index: -24.4300
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -2.1817
    Cell Significance Index: -24.9700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.2614
    Cell Significance Index: -117.4800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -2.2939
    Cell Significance Index: -38.3900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.3082
    Cell Significance Index: -80.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.5708
    Cell Significance Index: -120.8300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -2.6872
    Cell Significance Index: -67.0300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -2.6966
    Cell Significance Index: -58.2600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NCAM1 is a transmembrane protein with a single extracellular domain and a cytoplasmic tail. It belongs to the L1 family of CAMs, which are characterized by their ability to bind to other CAMs and extracellular matrix proteins. NCAM1 is highly glycosylated, which enables it to interact with various ligands and modulate its activity. The gene is encoded by a single copy in humans and is highly conserved across species, indicating its importance in evolution. **Pathways and Functions** NCAM1 is involved in multiple signaling pathways that regulate various cellular processes, including: 1. **Axon guidance**: NCAM1 plays a critical role in the development and maintenance of the nervous system by facilitating axon guidance and neuronal migration. 2. **Cell adhesion**: NCAM1 interacts with other CAMs and extracellular matrix proteins to regulate cell-cell interactions and tissue architecture. 3. **Immune system function**: NCAM1 is expressed on immune cells, including T cells and dendritic cells, and is involved in the regulation of immune responses, including the activation of T cells and the production of cytokines. 4. **Neuronal survival**: NCAM1 has been shown to promote neuronal survival and protect against neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. **Clinical Significance** Dysregulation of NCAM1 has been implicated in various diseases, including: 1. **Neurological disorders**: Mutations in the NCAM1 gene have been associated with neurodevelopmental disorders, such as autism spectrum disorder and schizophrenia. 2. **Cardiovascular disease**: NCAM1 has been shown to play a role in the development of cardiovascular disease, including hypertension and atherosclerosis. 3. **Cancer**: NCAM1 has been implicated in the progression and metastasis of various cancers, including breast cancer and lung cancer. 4. **Neurodegenerative diseases**: NCAM1 has been shown to have neuroprotective effects and may play a role in the prevention or treatment of neurodegenerative diseases. In conclusion, NCAM1 is a multifunctional gene that plays a critical role in various cellular processes, including cell adhesion, axon guidance, and immune system function. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms and clinical significance of NCAM1.

Genular Protein ID: 1850388257

Symbol: NCAM1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P13591 A8K8T8 P13592 P13593 Q05C58 Q15829 Q16180 Q16209 Q59FL7 Q86X47 Q96CJ3

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 4 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 3 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 6 RefSeq 4 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniLectin 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3253057

Title: Complete sequence and in vitro expression of a tissue-specific phosphatidylinositol-linked N-CAM isoform from skeletal muscle.

PubMed ID: 3253057

DOI: 10.1242/dev.104.1.165

PubMed ID: 1710251

Title: Molecular and functional analysis of human natural killer cell-associated neural cell adhesion molecule (N-CAM/CD56).

PubMed ID: 1710251

PubMed ID: 8075973

Title: Complementary DNA sequence encoding the major neural cell adhesion molecule isoform in a human small cell lung cancer cell line.

PubMed ID: 8075973

DOI: 10.1016/0169-5002(94)90660-2

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1339414

Title: Splicing of the VASE exon of neural cell adhesion molecule (NCAM) in human small-cell lung carcinoma (SCLC).

PubMed ID: 1339414

DOI: 10.1002/ijc.2910500124

PubMed ID: 2887295

Title: Human muscle neural cell adhesion molecule (N-CAM): identification of a muscle-specific sequence in the extracellular domain.

PubMed ID: 2887295

DOI: 10.1016/0092-8674(87)90178-4

PubMed ID: 3203385

Title: Alternative splicing generates a secreted form of N-CAM in muscle and brain.

PubMed ID: 3203385

DOI: 10.1016/0092-8674(88)90241-3

PubMed ID: 9774483

Title: Differential and cooperative polysialylation of the neural cell adhesion molecule by two polysialyltransferases, PST and STX.

PubMed ID: 9774483

DOI: 10.1074/jbc.273.43.28524

PubMed ID: 9696812

Title: The neural cell adhesion molecule is a receptor for rabies virus.

PubMed ID: 9696812

DOI: 10.1128/jvi.72.9.7181-7190.1998

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28810663

Title: Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4.

PubMed ID: 28810663

DOI: 10.1093/glycob/cwx057

PubMed ID: 32753727

Title: Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor.

PubMed ID: 32753727

DOI: 10.1038/s41467-020-17638-y

Sequence Information:

  • Length: 858
  • Mass: 94574
  • Checksum: FD3B9DE80D802554
  • Sequence:
    • MLQTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK DISWFSPNGE 
KLTPNQQRIS VVWNDDSSST LTIYNANIDD AGIYKCVVTG EDGSESEATV NVKIFQKLMF 
KNAPTPQEFR EGEDAVIVCD VVSSLPPTII WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK 
KTDEGTYRCE GRILARGEIN FKDIQVIVNV PPTIQARQNI VNATANLGQS VTLVCDAEGF 
PEPTMSWTKD GEQIEQEEDD EKYIFSDDSS QLTIKKVDKN DEAEYICIAE NKAGEQDATI 
HLKVFAKPKI TYVENQTAME LEEQVTLTCE ASGDPIPSIT WRTSTRNISS EEKASWTRPE 
KQETLDGHMV VRSHARVSSL TLKSIQYTDA GEYICTASNT IGQDSQSMYL EVQYAPKLQG 
PVAVYTWEGN QVNITCEVFA YPSATISWFR DGQLLPSSNY SNIKIYNTPS ASYLEVTPDS 
ENDFGNYNCT AVNRIGQESL EFILVQADTP SSPSIDQVEP YSSTAQVQFD EPEATGGVPI 
LKYKAEWRAV GEEVWHSKWY DAKEASMEGI VTIVGLKPET TYAVRLAALN GKGLGEISAA 
SEFKTQPVQG EPSAPKLEGQ MGEDGNSIKV NLIKQDDGGS PIRHYLVRYR ALSSEWKPEI 
RLPSGSDHVM LKSLDWNAEY EVYVVAENQQ GKSKAAHFVF RTSAQPTAIP ANGSPTSGLS 
TGAIVGILIV IFVLLLVVVD ITCYFLNKCG LFMCIAVNLC GKAGPGAKGK DMEEGKAAFS 
KDESKEPIVE VRTEEERTPN HDGGKHTEPN ETTPLTEPEK GPVEAKPECQ ETETKPAPAE 
VKTVPNDATQ TKENESKA

Genular Protein ID: 1138588714

Symbol: A0A087WWD4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WWD4

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 2 Pfam 3 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 884
  • Mass: 97345
  • Checksum: 2CED586CAA41E9F4
  • Sequence:
    • MLQTKDLIWT LFFLGTAVSL QVDIVPSQGE ISVGESKFFL CQVAGDAKDK DISWFSPNGE 
KLTPNQQRIS VVWNDDSSST LTIYNANIDD AGIYKCVVTG EDGSESEATV NVKIFQKLMF 
KNAPTPQEFR EGEDAVIVCD VVSSLPPTII WKHKGRDVIL KKDVRFIVLS NNYLQIRGIK 
KTDEGTYRCE GRILARGEIN FKDIQVIVNV PPTIQARQNI VNATANLGQS VTLVCDAEGF 
PEPTMSWTKD GEQIEQEEDD EKYIFSDDSS QLTIKKVDKN DEAEYICIAE NKAGEQDATI 
HLKVFAKPKI TYVENQTAME LEEQVTLTCE ASGDPIPSIT WRTSTRNISS EEKASWTRPE 
KQEVHAPWNW QVGRQKGQAG SAGFPGSHET LDGHMVVRSH ARVSSLTLKS IQYTDAGEYI 
CTASNTIGQD SQSMYLEVQY APKLQGPVAV YTWEGNQVNI TCEVFAYPSA TISWFRDGQL 
LPSSNYSNIK IYNTPSASYL EVTPDSENDF GNYNCTAVNR IGQESLEFIL VQADTPSSPS 
IDQVEPYSST AQVQFDEPEA TGGVPILKYK AEWRAVGEEV WHSKWYDAKE ASMEGIVTIV 
GLKPETTYAV RLAALNGKGL GEISAASEFK TQPVQGEPSA PKLEGQMGED GNSIKVNLIK 
QDDGGSPIRH YLVRYRALSS EWKPEIRLPS GSDHVMLKSL DWNAEYEVYV VAENQQGKSK 
AAHFVFRTSA QPTAIPANGS PTSGLSTGAI VGILIVIFVL LLVVVDITCY FLNKCGLFMC 
IAVNLCGKAG PGAKGKDMEE GKAAFSKDES KEPIVEVRTE EERTPNHDGG KHTEPNETTP 
LTEPEKGPVE AKPECQETET KPAPAEVKTV PNDATQTKEN ESKA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.