Details for: LUC7L3

Gene ID: 51747

Symbol: LUC7L3

Ensembl ID: ENSG00000108848

Description: LUC7 like 3 pre-mRNA splicing factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 862.5787
    Cell Significance Index: -134.1700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 483.2769
    Cell Significance Index: -122.5800
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 360.9197
    Cell Significance Index: -148.6800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 309.1570
    Cell Significance Index: -145.9600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 290.7272
    Cell Significance Index: -118.1100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 267.5232
    Cell Significance Index: -137.6100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 218.0554
    Cell Significance Index: -146.3200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 124.3476
    Cell Significance Index: -118.7200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 117.2143
    Cell Significance Index: -144.5200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 47.2291
    Cell Significance Index: -126.5200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 37.5109
    Cell Significance Index: -148.0200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 36.4029
    Cell Significance Index: -111.8100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 28.2694
    Cell Significance Index: -61.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.6761
    Cell Significance Index: 348.8800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 5.1347
    Cell Significance Index: 100.2200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 4.5200
    Cell Significance Index: 34.8400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.8011
    Cell Significance Index: 213.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 3.6830
    Cell Significance Index: 237.6100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.6773
    Cell Significance Index: 88.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.5271
    Cell Significance Index: 98.5700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.2904
    Cell Significance Index: 172.7600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.6195
    Cell Significance Index: 359.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.4414
    Cell Significance Index: 484.5100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4082
    Cell Significance Index: 483.0800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.3283
    Cell Significance Index: 121.2800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.3213
    Cell Significance Index: 832.6200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 2.1883
    Cell Significance Index: 167.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.1237
    Cell Significance Index: 96.2600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.0369
    Cell Significance Index: 1408.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0085
    Cell Significance Index: 57.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.9990
    Cell Significance Index: 360.3600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9881
    Cell Significance Index: 244.4500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 1.8003
    Cell Significance Index: 62.5600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.7590
    Cell Significance Index: 960.6300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.4867
    Cell Significance Index: 161.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.4751
    Cell Significance Index: 189.1000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 1.1451
    Cell Significance Index: 53.8200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0101
    Cell Significance Index: 99.9300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.0030
    Cell Significance Index: 27.3000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.9673
    Cell Significance Index: 427.6600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8201
    Cell Significance Index: 21.0800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.7293
    Cell Significance Index: 86.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.7243
    Cell Significance Index: 1115.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7141
    Cell Significance Index: 1344.6500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.6852
    Cell Significance Index: 46.0700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.6746
    Cell Significance Index: 11.5600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.5994
    Cell Significance Index: 1105.4300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.5776
    Cell Significance Index: 262.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.5518
    Cell Significance Index: 14.5100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5377
    Cell Significance Index: 341.5100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.4516
    Cell Significance Index: 614.1100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4336
    Cell Significance Index: 19.1800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4213
    Cell Significance Index: 14.8100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3564
    Cell Significance Index: 46.0500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1978
    Cell Significance Index: 13.9900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0798
    Cell Significance Index: 3.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0319
    Cell Significance Index: 5.4400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0308
    Cell Significance Index: 5.8600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0281
    Cell Significance Index: 20.6000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0056
    Cell Significance Index: 0.1500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0413
    Cell Significance Index: -2.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0852
    Cell Significance Index: -64.4700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0853
    Cell Significance Index: -63.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1239
    Cell Significance Index: -77.3800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1240
    Cell Significance Index: -2.0800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1504
    Cell Significance Index: -4.3100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2023
    Cell Significance Index: -114.1000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2783
    Cell Significance Index: -28.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3489
    Cell Significance Index: -56.7500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3517
    Cell Significance Index: -74.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4059
    Cell Significance Index: -28.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4146
    Cell Significance Index: -60.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4539
    Cell Significance Index: -130.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4719
    Cell Significance Index: -22.0000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.4817
    Cell Significance Index: -54.9900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5013
    Cell Significance Index: -37.3600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5580
    Cell Significance Index: -28.9900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7499
    Cell Significance Index: -78.0800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7974
    Cell Significance Index: -91.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.8883
    Cell Significance Index: -103.5200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -1.0429
    Cell Significance Index: -25.4500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.1037
    Cell Significance Index: -16.3000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4284
    Cell Significance Index: -45.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.4484
    Cell Significance Index: -31.3800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.4905
    Cell Significance Index: -118.0500
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.5851
    Cell Significance Index: -40.5000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.6056
    Cell Significance Index: -34.3200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -1.7056
    Cell Significance Index: -23.2700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.7373
    Cell Significance Index: -20.7100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.7636
    Cell Significance Index: -25.3300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.7829
    Cell Significance Index: -37.3200
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -1.7876
    Cell Significance Index: -27.1500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -2.0066
    Cell Significance Index: -46.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.1390
    Cell Significance Index: -53.4700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -2.3042
    Cell Significance Index: -141.2700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -2.3573
    Cell Significance Index: -69.2300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -2.5378
    Cell Significance Index: -72.4200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -2.6512
    Cell Significance Index: -33.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.8733
    Cell Significance Index: -84.6300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -2.9105
    Cell Significance Index: -36.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The LUC7L3 gene is a member of the Luc7-like protein family, which is characterized by its ability to bind to specific RNA sequences and facilitate the recognition of splice sites. The gene is composed of a single coding exon and is highly conserved across species, suggesting its essential role in RNA splicing. The LUC7L3 protein is a heterodimeric complex, consisting of two subunits, LC7L3A and LC7L3B, which interact with the U1 snRNP complex to recognize and bind to the 5' splice site of introns. The gene is also highly expressed in specific cell types, such as lens epithelial cells and inhibitory interneurons, suggesting its involvement in tissue-specific gene regulation. **Pathways and Functions:** The LUC7L3 gene is involved in multiple cellular pathways, including: 1. **RNA Splicing:** LUC7L3 plays a crucial role in the recognition and binding of splice sites, facilitating the removal of introns and the joining of exons to form mature mRNAs. 2. **DNA Binding:** The LUC7L3 protein binds to specific DNA sequences, regulating gene expression and transcription. 3. **Metabolism of RNA:** LUC7L3 is involved in the regulation of RNA metabolism, including the processing of capped intron-containing pre-mRNAs. 4. **mRNA Binding:** The LUC7L3 protein interacts with specific mRNA sequences, regulating mRNA stability and translation. **Clinical Significance:** The LUC7L3 gene has significant implications for the diagnosis and treatment of diseases related to aberrant RNA splicing, such as: 1. **Spinal Muscular Atrophy (SMA):** LUC7L3 mutations have been identified in patients with SMA, a genetic disorder characterized by progressive muscle weakness and wasting. 2. **Amyotrophic Lateral Sclerosis (ALS):** Aberrant RNA splicing has been implicated in the development of ALS, a neurodegenerative disorder characterized by progressive motor neuron loss. 3. **Cancer:** Dysregulation of RNA splicing has been linked to the development and progression of various cancers, including breast, lung, and colon cancer. In conclusion, the LUC7L3 gene is a critical component of the RNA splicing machinery, playing a vital role in the regulation of gene expression and the development of novel therapeutic strategies for diseases related to aberrant RNA splicing. Further research is needed to fully elucidate the function and significance of LUC7L3 and its implications for human health.

Genular Protein ID: 3698161355

Symbol: LC7L3_HUMAN

Name: Luc7-like protein 3

UniProtKB Accession Codes:

O95232 B3KN54 D3DTY1 Q6PHR9 Q9NUY0 Q9P2S7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 10 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10631324

Title: CROP/Luc7A, a novel serine/arginine-rich nuclear protein, isolated from cisplatin-resistant cell line.

PubMed ID: 10631324

DOI: 10.1016/s0014-5793(99)01744-5

PubMed ID: 16462885

Title: Identification of a family of DNA-binding proteins with homology to RNA splicing factors.

PubMed ID: 16462885

DOI: 10.1139/o05-139

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10754390

Title: Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells.

PubMed ID: 10754390

DOI: 10.1007/bf02256622

PubMed ID: 12565863

Title: Effect of cisplatin treatment on speckled distribution of a serine/arginine-rich nuclear protein CROP/Luc7A.

PubMed ID: 12565863

DOI: 10.1016/s0006-291x(02)03017-6

PubMed ID: 15798186

Title: A novel SR-related protein is required for the second step of pre-mRNA splicing.

PubMed ID: 15798186

DOI: 10.1128/mcb.25.8.2969-2980.2005

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18663000

Title: Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.

PubMed ID: 18663000

DOI: 10.1128/mcb.00560-08

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19574390

Title: Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing.

PubMed ID: 19574390

DOI: 10.1126/science.1175865

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23604122

Title: RRP1B is a metastasis modifier that regulates the expression of alternative mRNA isoforms through interactions with SRSF1.

PubMed ID: 23604122

DOI: 10.1038/onc.2013.133

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 432
  • Mass: 51466
  • Checksum: E75F55EC0137310C
  • Sequence:
    • MISAAQLLDE LMGRDRNLAP DEKRSNVRWD HESVCKYYLC GFCPAELFTN TRSDLGPCEK 
IHDENLRKQY EKSSRFMKVG YERDFLRYLQ SLLAEVERRI RRGHARLALS QNQQSSGAAG 
PTGKNEEKIQ VLTDKIDVLL QQIEELGSEG KVEEAQGMMK LVEQLKEERE LLRSTTSTIE 
SFAAQEKQME VCEVCGAFLI VGDAQSRVDD HLMGKQHMGY AKIKATVEEL KEKLRKRTEE 
PDRDERLKKE KQEREEREKE REREREERER KRRREEEERE KERARDRERR KRSRSRSRHS 
SRTSDRRCSR SRDHKRSRSR ERRRSRSRDR RRSRSHDRSE RKHRSRSRDR RRSKSRDRKS 
YKHRSKSRDR EQDRKSKEKE KRGSDDKKSS VKSGSREKQS EDTNTESKES DTKNEVNGTS 
EDIKSEGDTQ SN

Genular Protein ID: 4226604782

Symbol: A8K3C5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K3C5

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 2

Sequence Information:

  • Length: 432
  • Mass: 51442
  • Checksum: 048B552473EC5D66
  • Sequence:
    • MISAAQLLDE LMGRDRNLAP DEKRSNVRWD HESVCKYYLC GFCPAELFTN TRSDLGPCEK 
ILDENLRKQY EKSSRFMKVG YERDFLRYLQ SLLAEVERRI RRGHARLALS QNQQSSGAAG 
PTGKNEEKIQ VLTDKIDVLL QQIEELGSEG KVEEAQGMMK LVEQLKEERE LLRSTTSTIE 
SFAAQEKQME VCEVCGAFLI VGDAQSRVDD HLMGKQHMGY AKIKATVEEL KEKLRKRTEE 
PDRDERLKKE KQEREEREKE REREREERER KRRREEEERE KERARDRERR KRSRSRSRHS 
SRTSDRRCSR SRDHKRSRSR ERRRSRSRDR RRSRSHDRSE RKHRSRSRDR RRSKSRDRKS 
YKHRSKSRDR EQDRKSKEKE KRGSDDKKSS VKSGSREKQS EDTNTESKES DTKNEVNGTS 
EDIKSEGDTQ SN

Genular Protein ID: 2457782887

Symbol: J3KPP4_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KPP4

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 5 GeneTree 1 HGNC 1 IntAct 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.M111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 489
  • Mass: 58220
  • Checksum: A28EB1940E080570
  • Sequence:
    • MISAAQLLDE LMGRDRNLAP DEKRSNVRWD HESVCKYYLC GFCPAELFTN TRSDLGPCEK 
IHDENLRKQY EKSSRFMKVG YERDFLRYLQ SLLAEVERRI RRGHARLALS QNQQSSGAAG 
PTGKNEEKIQ VLTDKIDVLL QQIEELGSEG KVEEAQGMMK LVEQLKEERE LLRSTTSTIE 
SFAAQEKQME VCEVCGAFLI VGDAQSRVDD HLMGKQHMGY AKIKATVEEL KEKLRKRTEE 
PDRDERLKKE KQEREEREKE REREREERER KRRREEEERE KERARDRERR KRSRSRSRHS 
SRTSDRRCSR SRDHKRSRSR ERRRSRSRDR RRSRSHDRSE RKHRSRSRDR RRSKSRDRKS 
YKHRSKSRDR EQDRKSKEKE KRGSDDKKSS VKSGSREKQS EDTNTESKES DTKNEVNGTS 
EDIKSEVQRK YAQMKMELSR VRRHTKASSE GKDSVVLQNI LRYIVLSQLF CSRLVPPLVC 
LFGNYRPHL

Genular Protein ID: 477104419

Symbol: Q86Y74_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86Y74

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 IntAct 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 251
  • Mass: 28926
  • Checksum: 368F730B37A58A51
  • Sequence:
    • MISAAQLLDE LMGRDRNLAP DEKRSNVRWD HESVCKYYLC GFCPAELFTN TRSDLGPCEK 
IHDENLRKQY EKSSRFMKVG YERDFLRYLQ SLLAEVERRI RRGHARLALS QNQQSSGAAG 
PTGKNEEKIQ VLTDKIDVLL QQIEELGSEG KVEEAQGMMK LVEQLKEERE LLRSTTSTIE 
SFAAQEKQME VCEVCGAFLI VGDAQSRVDD HLMGKQHMGY AKIKATVEEL KEKLRKRTEE 
PDRDERLKKK K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.