Details for: PRKG1

Gene ID: 5592

Symbol: PRKG1

Ensembl ID: ENSG00000185532

Description: protein kinase cGMP-dependent 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: contractile cell (CL0000183)
    Fold Change: 8.55
    Marker Score: 4635
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 7.81
    Marker Score: 4342
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 7.56
    Marker Score: 255372
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 5.67
    Marker Score: 3732
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 5.44
    Marker Score: 13619
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 5.12
    Marker Score: 114451
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 4.94
    Marker Score: 16553
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 4.33
    Marker Score: 4126
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 4.3
    Marker Score: 5781
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.95
    Marker Score: 7601
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.93
    Marker Score: 4762
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 3.89
    Marker Score: 13847
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.75
    Marker Score: 8241
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 3.75
    Marker Score: 2887.5
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.54
    Marker Score: 62883
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 3.45
    Marker Score: 1815
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 3.35
    Marker Score: 3853
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.2
    Marker Score: 935
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.09
    Marker Score: 66043
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 3.01
    Marker Score: 1755
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.86
    Marker Score: 743
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.85
    Marker Score: 45822
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.81
    Marker Score: 1852
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.68
    Marker Score: 1567
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.67
    Marker Score: 1281
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.63
    Marker Score: 1012
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.59
    Marker Score: 1084
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.5
    Marker Score: 4199
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.49
    Marker Score: 787
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.46
    Marker Score: 1380
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.44
    Marker Score: 89879
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.36
    Marker Score: 2938
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.35
    Marker Score: 2034
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.33
    Marker Score: 46306
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.32
    Marker Score: 4223
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 2.29
    Marker Score: 863
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 2.23
    Marker Score: 1978
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.19
    Marker Score: 1274
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.14
    Marker Score: 6105
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 2.09
    Marker Score: 1396
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 2.06
    Marker Score: 21320
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.98
    Marker Score: 733
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.92
    Marker Score: 526
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.91
    Marker Score: 4494
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.89
    Marker Score: 17968
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.87
    Marker Score: 16069
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.86
    Marker Score: 8591
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.83
    Marker Score: 573
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.82
    Marker Score: 3708.5
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.82
    Marker Score: 111714
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.81
    Marker Score: 461
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.77
    Marker Score: 642
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.71
    Marker Score: 6954
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.7
    Marker Score: 2114
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.67
    Marker Score: 1179
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.65
    Marker Score: 990
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.64
    Marker Score: 917
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.59
    Marker Score: 6643
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.53
    Marker Score: 442
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.53
    Marker Score: 6395
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.51
    Marker Score: 5363
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.5
    Marker Score: 2124
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.49
    Marker Score: 1611
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.49
    Marker Score: 1132
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.42
    Marker Score: 1718
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.39
    Marker Score: 159516
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.38
    Marker Score: 956
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.37
    Marker Score: 21471
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 1.37
    Marker Score: 902
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.37
    Marker Score: 12873
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 861
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.36
    Marker Score: 1441
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.35
    Marker Score: 668
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.34
    Marker Score: 3158
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 1.33
    Marker Score: 751
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.28
    Marker Score: 412
  • Cell Name: pericyte (CL0000669)
    Fold Change: 1.27
    Marker Score: 744
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.25
    Marker Score: 6719
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.23
    Marker Score: 598
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 1.23
    Marker Score: 494
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.22
    Marker Score: 320
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 1.21
    Marker Score: 862
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.2
    Marker Score: 455
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.14
    Marker Score: 6837
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 1.14
    Marker Score: 301
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 1.13
    Marker Score: 333
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 1.09
    Marker Score: 521
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.08
    Marker Score: 4485
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.07
    Marker Score: 364
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 1.07
    Marker Score: 979
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.05
    Marker Score: 532
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 1.04
    Marker Score: 265
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.04
    Marker Score: 328
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 1.03
    Marker Score: 310.5
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.01
    Marker Score: 1251
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 1.01
    Marker Score: 871
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 1
    Marker Score: 260
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71758
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47985
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.99
    Marker Score: 959

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Other Information

**Key Characteristics:** PRKG1 is a serine/threonine kinase that is activated by cGMP, which is produced by the enzyme guanylate cyclase. The activation of PRKG1 leads to the phosphorylation of downstream targets, resulting in various cellular responses. PRKG1 has a unique substrate specificity, with a preference for phosphorylating serine and threonine residues. The kinase has a high affinity for cGMP, allowing it to be activated in response to changes in cGMP levels. PRKG1 is also known to interact with other signaling molecules, such as Rap1 and beta-catenin, to regulate various cellular processes. **Pathways and Functions:** PRKG1 is involved in several signaling pathways, including: 1. **Acrosomal vesicle formation:** PRKG1 regulates the formation of acrosomal vesicles in sperm cells, which is essential for fertilization. 2. **Actin cytoskeleton organization:** PRKG1 phosphorylates actin and myosin light chain, regulating actin cytoskeleton organization and cell motility. 3. **Adaptive immune system:** PRKG1 modulates the adaptive immune response by regulating T-cell activation and differentiation. 4. **Cardiac muscle cell development:** PRKG1 is involved in the development and function of cardiac muscle cells, regulating cell growth and differentiation. 5. **Neuronal development and function:** PRKG1 regulates neuronal development and function, including axon guidance and synaptic plasticity. **Clinical Significance:** Dysregulation of PRKG1 has been implicated in various diseases, including: 1. **Cardiovascular diseases:** PRKG1 is involved in the regulation of vascular smooth muscle cell migration and proliferation, which is critical in the development of cardiovascular diseases. 2. **Neurodegenerative diseases:** PRKG1 has been implicated in the regulation of neuronal development and function, which may contribute to the pathogenesis of neurodegenerative diseases such as Alzheimer's and Parkinson's. 3. **Cancer:** PRKG1 has been shown to regulate cell growth and differentiation, which may contribute to the development of cancer. 4. **Respiratory diseases:** PRKG1 is involved in the regulation of alveolar type 2 fibroblast function, which is critical in the development of respiratory diseases such as chronic obstructive pulmonary disease (COPD). In conclusion, PRKG1 is a multifunctional enzyme that plays a crucial role in various cellular processes, including actin cytoskeleton organization, adaptive immune system regulation, and cardiac muscle cell development. Dysregulation of PRKG1 has been implicated in various diseases, highlighting the importance of this enzyme in maintaining cellular homeostasis. Further research is needed to fully elucidate the mechanisms by which PRKG1 regulates cellular processes and to explore its therapeutic potential in disease models.

Genular Protein ID: 2730545372

Symbol: KGP1_HUMAN

Name: cGMP-dependent protein kinase 1

UniProtKB Accession Codes:

Q13976 A5YM56 B3KSF3 E2PU10 P14619 Q5JP05 Q5JSJ6 Q6P5T7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CPTAC 2 CTD 1 ChEBI 23 ChEMBL 1 ChiTaRS 1 DIP 2 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 3 EMBL 84 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 36 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 43 PDBsum 26 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 7 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 2 Rhea 6 SABIO-RK 1 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2792381

Title: Molecular cloning and predicted full-length amino acid sequence of the type I beta isozyme of cGMP-dependent protein kinase from human placenta. Tissue distribution and developmental changes in rat.

PubMed ID: 2792381

DOI: 10.1016/0014-5793(89)81114-7

PubMed ID: 8613202

Title: cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase.

PubMed ID: 8613202

DOI: 10.1161/01.hyp.27.3.552

PubMed ID: 9192852

Title: Characterization of the human gene encoding the type I alpha and type I beta cGMP-dependent protein kinase (PRKG1).

PubMed ID: 9192852

DOI: 10.1006/geno.1997.4743

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8182057

Title: cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets.

PubMed ID: 8182057

DOI: 10.1016/s0021-9258(17)36652-8

PubMed ID: 10567269

Title: Regulation of myosin phosphatase by a specific interaction with cGMP-dependent protein kinase Ialpha.

PubMed ID: 10567269

DOI: 10.1126/science.286.5444.1583

PubMed ID: 11162591

Title: cGMP-dependent protein kinase phosphorylates and inactivates RhoA.

PubMed ID: 11162591

DOI: 10.1006/bbrc.2000.4194

PubMed ID: 12082086

Title: cGMP-dependent protein kinase I beta physically and functionally interacts with the transcriptional regulator TFII-I.

PubMed ID: 12082086

DOI: 10.1074/jbc.m112332200

PubMed ID: 11723116

Title: Regulation of cGMP-specific phosphodiesterase (PDE5) phosphorylation in smooth muscle cells.

PubMed ID: 11723116

DOI: 10.1074/jbc.m106562200

PubMed ID: 14608379

Title: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure.

PubMed ID: 14608379

DOI: 10.1038/nm958

PubMed ID: 15194681

Title: Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to cyclic nucleotides.

PubMed ID: 15194681

DOI: 10.1074/jbc.m405957200

PubMed ID: 16990611

Title: IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.

PubMed ID: 16990611

DOI: 10.1182/blood-2005-10-026294

PubMed ID: 17904578

Title: Interactions between the leucine-zipper motif of cGMP-dependent protein kinase and the C-terminal region of the targeting subunit of myosin light chain phosphatase.

PubMed ID: 17904578

DOI: 10.1016/j.jmb.2007.08.049

PubMed ID: 18782776

Title: Probing the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase.

PubMed ID: 18782776

DOI: 10.1074/jbc.m804916200

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20716671

Title: cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.

PubMed ID: 20716671

DOI: 10.1124/pr.110.002907

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21402151

Title: Functional regulation of transient receptor potential canonical 7 by cGMP-dependent protein kinase Ialpha.

PubMed ID: 21402151

DOI: 10.1016/j.cellsig.2011.03.005

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 16131665

Title: Rapid and accurate structure determination of coiled-coil domains using NMR dipolar couplings: application to cGMP-dependent protein kinase Ialpha.

PubMed ID: 16131665

DOI: 10.1110/ps.051528905

PubMed ID: 20826808

Title: A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific anchoring.

PubMed ID: 20826808

DOI: 10.1074/jbc.c110.161430

PubMed ID: 21526164

Title: Co-crystal structures of PKG Ibeta (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding.

PubMed ID: 21526164

DOI: 10.1371/journal.pone.0018413

PubMed ID: 25271401

Title: Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: insights for cGMP-dependent protein kinase agonist design.

PubMed ID: 25271401

DOI: 10.1021/bi501012v

PubMed ID: 24239458

Title: Structural basis for cyclic-nucleotide selectivity and cGMP-selective activation of PKG I.

PubMed ID: 24239458

DOI: 10.1016/j.str.2013.09.021

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 23910461

Title: Recurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.

PubMed ID: 23910461

DOI: 10.1016/j.ajhg.2013.06.019

Sequence Information:

  • Length: 671
  • Mass: 76364
  • Checksum: 51389502A5E5FBD2
  • Sequence:
    • MSELEEDFAK ILMLKEERIK ELEKRLSEKE EEIQELKRKL HKCQSVLPVP STHIGPRTTR 
AQGISAEPQT YRSFHDLRQA FRKFTKSERS KDLIKEAILD NDFMKNLELS QIQEIVDCMY 
PVEYGKDSCI IKEGDVGSLV YVMEDGKVEV TKEGVKLCTM GPGKVFGELA ILYNCTRTAT 
VKTLVNVKLW AIDRQCFQTI MMRTGLIKHT EYMEFLKSVP TFQSLPEEIL SKLADVLEET 
HYENGEYIIR QGARGDTFFI ISKGTVNVTR EDSPSEDPVF LRTLGKGDWF GEKALQGEDV 
RTANVIAAEA VTCLVIDRDS FKHLIGGLDD VSNKAYEDAE AKAKYEAEAA FFANLKLSDF 
NIIDTLGVGG FGRVELVQLK SEESKTFAMK ILKKRHIVDT RQQEHIRSEK QIMQGAHSDF 
IVRLYRTFKD SKYLYMLMEA CLGGELWTIL RDRGSFEDST TRFYTACVVE AFAYLHSKGI 
IYRDLKPENL ILDHRGYAKL VDFGFAKKIG FGKKTWTFCG TPEYVAPEII LNKGHDISAD 
YWSLGILMYE LLTGSPPFSG PDPMKTYNII LRGIDMIEFP KKIAKNAANL IKKLCRDNPS 
ERLGNLKNGV KDIQKHKWFE GFNWEGLRKG TLTPPIIPSV ASPTDTSNFD SFPEDNDEPP 
PDDNSGWDID F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.