Details for: ARHGEF4

Gene ID: 50649

Symbol: ARHGEF4

Ensembl ID: ENSG00000136002

Description: Rho guanine nucleotide exchange factor 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 188.4339
    Cell Significance Index: -29.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 115.6742
    Cell Significance Index: -29.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 23.7721
    Cell Significance Index: -29.3100
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 6.1516
    Cell Significance Index: 86.0200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 4.3218
    Cell Significance Index: 1243.5000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 4.2943
    Cell Significance Index: 58.5900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 4.1179
    Cell Significance Index: 115.0800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 3.3374
    Cell Significance Index: 41.4000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.3718
    Cell Significance Index: 104.9100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.3545
    Cell Significance Index: 89.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.1559
    Cell Significance Index: 432.4800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.7776
    Cell Significance Index: 25.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.5491
    Cell Significance Index: 104.1600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.1655
    Cell Significance Index: 33.2600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.1376
    Cell Significance Index: 24.9100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0917
    Cell Significance Index: 391.5800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.8444
    Cell Significance Index: 14.6000
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.7667
    Cell Significance Index: 8.5200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7162
    Cell Significance Index: 495.3800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4819
    Cell Significance Index: 30.3700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2115
    Cell Significance Index: 9.5900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1956
    Cell Significance Index: 37.2300
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: 0.1904
    Cell Significance Index: 2.5700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1713
    Cell Significance Index: 108.8300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1205
    Cell Significance Index: 108.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0884
    Cell Significance Index: 39.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0867
    Cell Significance Index: 4.5500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0327
    Cell Significance Index: 0.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0232
    Cell Significance Index: 43.6100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0172
    Cell Significance Index: 2.9300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0168
    Cell Significance Index: 1.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0037
    Cell Significance Index: 0.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0023
    Cell Significance Index: -0.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0080
    Cell Significance Index: -14.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0123
    Cell Significance Index: -18.9400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0162
    Cell Significance Index: -22.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0204
    Cell Significance Index: -11.1700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0349
    Cell Significance Index: -2.1400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0370
    Cell Significance Index: -27.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0408
    Cell Significance Index: -30.2400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0427
    Cell Significance Index: -7.6900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0445
    Cell Significance Index: -33.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0453
    Cell Significance Index: -5.5700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0467
    Cell Significance Index: -21.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0525
    Cell Significance Index: -8.5400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0562
    Cell Significance Index: -35.0900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0573
    Cell Significance Index: -32.3400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0649
    Cell Significance Index: -12.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0733
    Cell Significance Index: -10.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0760
    Cell Significance Index: -7.5100
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.0786
    Cell Significance Index: -0.9000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.1046
    Cell Significance Index: -1.1400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1301
    Cell Significance Index: -3.1200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.1465
    Cell Significance Index: -1.9000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1523
    Cell Significance Index: -20.9100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.1539
    Cell Significance Index: -16.7500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1574
    Cell Significance Index: -3.3400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1652
    Cell Significance Index: -34.8000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1823
    Cell Significance Index: -2.6100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1912
    Cell Significance Index: -2.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2011
    Cell Significance Index: -5.8000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2034
    Cell Significance Index: -26.2800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2432
    Cell Significance Index: -31.1800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2486
    Cell Significance Index: -29.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2640
    Cell Significance Index: -26.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2659
    Cell Significance Index: -30.9900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2672
    Cell Significance Index: -30.6100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2706
    Cell Significance Index: -5.3500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2787
    Cell Significance Index: -29.0200
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.2827
    Cell Significance Index: -2.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2864
    Cell Significance Index: -7.1600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.3133
    Cell Significance Index: -7.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3161
    Cell Significance Index: -21.8600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3367
    Cell Significance Index: -6.7600
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.3435
    Cell Significance Index: -2.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3449
    Cell Significance Index: -27.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3471
    Cell Significance Index: -26.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3559
    Cell Significance Index: -25.1700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.3606
    Cell Significance Index: -21.6500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3737
    Cell Significance Index: -27.8500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3765
    Cell Significance Index: -11.9900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4068
    Cell Significance Index: -8.7900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4126
    Cell Significance Index: -13.5100
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.4132
    Cell Significance Index: -4.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4249
    Cell Significance Index: -27.4200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.4304
    Cell Significance Index: -4.0800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.4397
    Cell Significance Index: -19.1200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4592
    Cell Significance Index: -23.9200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4943
    Cell Significance Index: -12.3300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5078
    Cell Significance Index: -26.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.5267
    Cell Significance Index: -24.7600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5478
    Cell Significance Index: -19.1900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5644
    Cell Significance Index: -11.7800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.6260
    Cell Significance Index: -7.9000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.6346
    Cell Significance Index: -15.8500
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.6626
    Cell Significance Index: -10.0800
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.6697
    Cell Significance Index: -8.7400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.6702
    Cell Significance Index: -14.5200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.6767
    Cell Significance Index: -31.5500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6955
    Cell Significance Index: -25.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ARHGEF4 is a guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP in small GTPases, thereby activating them. This activity is essential for the regulation of various cellular processes, including cell migration, cytoskeleton reorganization, and cell death signaling. The gene's expression is highly dynamic, with significant changes observed in response to cellular stress, growth factors, and other stimuli. The protein encoded by ARHGEF4 exhibits specific binding properties, interacting with a range of signaling molecules, including G-proteins, receptor tyrosine kinases, and transcription factors. **Pathways and Functions:** ARHGEF4 is involved in a wide range of signaling pathways, including: 1. **Cdc42 GTPase Cycle**: ARHGEF4 regulates the activity of Cdc42, a small GTPase involved in cell migration, cytoskeleton reorganization, and cell polarity. 2. **RhoA GTPase Cycle**: The gene's product activates RhoA, a small GTPase that regulates cell migration, cytoskeleton reorganization, and cell death signaling. 3. **Rac1 GTPase Cycle**: ARHGEF4 regulates the activity of Rac1, a small GTPase involved in cell migration, cytoskeleton reorganization, and cell survival. 4. **G-protein Coupled Receptor (GPCR) Signaling**: The gene's product interacts with G-proteins, modulating the activity of GPCRs and influencing cellular responses to ligand binding. 5. **Death Receptor Signaling**: ARHGEF4 is involved in the regulation of death receptor signaling, influencing cell death and apoptosis. **Clinical Significance:** Dysregulation of ARHGEF4 has been implicated in various diseases, including: 1. **Neurodegenerative Disorders**: Alterations in ARHGEF4 expression have been observed in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. 2. **Cancer**: The gene's product is involved in the regulation of cell migration and invasion in various cancers, including breast, lung, and colon cancer. 3. **Neurological Disorders**: ARHGEF4 dysregulation has been linked to neurological disorders, such as multiple sclerosis and amyotrophic lateral sclerosis (ALS). In conclusion, ARHGEF4 plays a critical role in regulating various intracellular signaling pathways, influencing cellular homeostasis and regulating cellular responses to environmental stimuli. Further research is needed to fully elucidate the gene's function and its implications in human disease.

Genular Protein ID: 2246978369

Symbol: ARHG4_HUMAN

Name: Rho guanine nucleotide exchange factor 4

UniProtKB Accession Codes:

Q9NR80 Q9HDC6 Q9UPP0

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 5 RefSeq 2 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10873612

Title: Isolation of two novel human RhoGEFs, ARHGEF3 and ARHGEF4, in 3p13-21 and 2q22.

PubMed ID: 10873612

DOI: 10.1006/bbrc.2000.2925

PubMed ID: 10947987

Title: Asef, a link between the tumor suppressor APC and G-protein signaling.

PubMed ID: 10947987

DOI: 10.1126/science.289.5482.1194

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12598901

Title: Mutated APC and Asef are involved in the migration of colorectal tumour cells.

PubMed ID: 12598901

DOI: 10.1038/ncb937

PubMed ID: 17145773

Title: Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.

PubMed ID: 17145773

DOI: 10.1128/mcb.01608-06

PubMed ID: 17599059

Title: Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.

PubMed ID: 17599059

DOI: 10.1038/sj.onc.1210574

PubMed ID: 19893577

Title: The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.

PubMed ID: 19893577

DOI: 10.1038/embor.2009.233

PubMed ID: 17190834

Title: Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism.

PubMed ID: 17190834

DOI: 10.1074/jbc.c600234200

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 690
  • Mass: 79067
  • Checksum: 47E5B61C91950CD2
  • Sequence:
    • MPWEEPAGEK PSCSHSQKAF HMEPAQKPCF TTDMVTWALL CISAETVRGE APSQPRGIPH 
RSPVSVDDLW LEKTQRKKLQ KQAHVERRLH IGAVHKDGVK CWRKTIITSP ESLNLPRRSH 
PLSQSAPTGL NHMGWPEHTP GTAMPDGALD TAVCADEVGS EEDLYDDLHS SSHHYSHPGG 
GGEQLAINEL ISDGSVVCAE ALWDHVTMDD QELGFKAGDV IEVMDATNRE WWWGRVADGE 
GWFPASFVRL RVNQDEPADD DAPLAGNSGA EDGGAEAQSS KDQMRTNVIN EILSTERDYI 
KHLRDICEGY VRQCRKRADM FSEEQLRTIF GNIEDIYRCQ KAFVKALEQR FNRERPHLSE 
LGACFLEHQA DFQIYSEYCN NHPNACVELS RLTKLSKYVY FFEACRLLQK MIDISLDGFL 
LTPVQKICKY PLQLAELLKY THPQHRDFKD VEAALHAMKN VAQLINERKR RLENIDKIAQ 
WQSSIEDWEG EDLLVRSSEL IYSGELTRVT QPQAKSQQRM FFLFDHQLIY CKKDLLRRDV 
LYYKGRLDMD GLEVVDLEDG KDRDLHVSIK NAFRLHRGAT GDSHLLCTRK PEQKQRWLKA 
FAREREQVQL DQETGFSITE LQRKQAMLNA SKQQVTGKPK AVGRPCYLTR QKHPALPSNR 
PQQQVLVLAE PRRKPSTFWH SISRLAPFRK

Genular Protein ID: 848468211

Symbol: Q9NTG0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9NTG0

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 3 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIR 1 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 2 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 496
  • Mass: 57740
  • Checksum: 9DE2EA6A3F186AB2
  • Sequence:
    • SVVCAEALWD HVTMDDQELG FKAGDVIEVM DATNREWWWG RVADGEGWFP ASFVRLRVNQ 
DEPADDDAPL AGNSGAEDGG AEAQSSKDQM RTNVINEILS TERDYIKHLR DICEGYVRQC 
RKRADMFSEE QLRTIFGNIE DIYRCQKAFV KALEQRFNRE RPHLSELGAC FLEHQADFQI 
YSEYCNNHPN ACVELSRLTK LSKYVYFFEA CRLLQKMIDI SLDGFLLTPV QKICKYPLQL 
AELLKYTHPQ HRDFKDVEAA LHAMKNVAQL INERKRRLEN IDKIAQWQSS IEDWEGEDLL 
VRSSELIYSG ELTRVTQPQA KSQQRMFFLF DHQLIYCKKD LLRRDVLYYK GRLDMDGLEV 
VDLEDGKDRD LHVSIKNAFR LHRGATGDSH LLCTRKPEQK QRWLKAFARE REQVQLDQET 
GFSITELQRK QAMLNASKQQ VTGKPKAVGR PCYLTRQKHP ALPSNRPQQQ VLVLAEPRRK 
PSTFWHSISR LAPFRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.