Details for: GPM6B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 521.8418
Cell Significance Index: -81.1700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 320.4893
Cell Significance Index: -81.2900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 164.8300
Cell Significance Index: -77.8200 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 66.2798
Cell Significance Index: -81.7200 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 62.8703
Cell Significance Index: -60.0300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 28.4412
Cell Significance Index: -76.1900 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 24.8254
Cell Significance Index: -76.2500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 20.5547
Cell Significance Index: -81.1100 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 6.4734
Cell Significance Index: 90.5200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 4.1706
Cell Significance Index: 280.4300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 3.7765
Cell Significance Index: 107.7700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 3.2554
Cell Significance Index: 200.0900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.0248
Cell Significance Index: 606.7700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.5033
Cell Significance Index: 140.4700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.4411
Cell Significance Index: 92.4400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.4398
Cell Significance Index: 107.9200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.3883
Cell Significance Index: 856.6400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.3008
Cell Significance Index: 55.1800 - Cell Name: odontoblast (CL0000060)
Fold Change: 2.1250
Cell Significance Index: 272.4100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.0084
Cell Significance Index: 126.5800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.9012
Cell Significance Index: 116.4300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6725
Cell Significance Index: 465.1600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.6281
Cell Significance Index: 40.5300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6230
Cell Significance Index: 562.5200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1699
Cell Significance Index: 27.6400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1622
Cell Significance Index: 30.8600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1284
Cell Significance Index: 2.2000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0708
Cell Significance Index: 38.6900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0048
Cell Significance Index: 0.6600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0061
Cell Significance Index: -11.5600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0070
Cell Significance Index: -0.3300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0210
Cell Significance Index: -2.0800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0230
Cell Significance Index: -14.6100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0234
Cell Significance Index: -36.0500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0284
Cell Significance Index: -38.6400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0343
Cell Significance Index: -63.1700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0433
Cell Significance Index: -1.5200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0504
Cell Significance Index: -37.3300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0629
Cell Significance Index: -6.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0647
Cell Significance Index: -3.4000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0683
Cell Significance Index: -30.2000 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.0819
Cell Significance Index: -0.6300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0875
Cell Significance Index: -2.5200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0898
Cell Significance Index: -65.8500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1074
Cell Significance Index: -19.3600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1085
Cell Significance Index: -67.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1107
Cell Significance Index: -83.8200 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1328
Cell Significance Index: -0.9000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1360
Cell Significance Index: -61.7400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1361
Cell Significance Index: -76.7800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1524
Cell Significance Index: -3.8100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1537
Cell Significance Index: -30.5100 - Cell Name: glioblast (CL0000030)
Fold Change: -0.2166
Cell Significance Index: -1.3600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2224
Cell Significance Index: -27.3500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2325
Cell Significance Index: -66.8900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2478
Cell Significance Index: -11.2300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2757
Cell Significance Index: -40.0800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2975
Cell Significance Index: -34.6700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3465
Cell Significance Index: -4.1300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.3596
Cell Significance Index: -10.0500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3947
Cell Significance Index: -83.1300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.4153
Cell Significance Index: -70.9200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.4285
Cell Significance Index: -29.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.4320
Cell Significance Index: -9.3600 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: -0.4421
Cell Significance Index: -4.7400 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.4615
Cell Significance Index: -7.9800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.5545
Cell Significance Index: -33.2900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.5771
Cell Significance Index: -58.9500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.6536
Cell Significance Index: -77.0800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6970
Cell Significance Index: -42.7300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.7152
Cell Significance Index: -9.5400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.7211
Cell Significance Index: -82.6100 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.7242
Cell Significance Index: -7.5600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.7378
Cell Significance Index: -54.9900 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.7736
Cell Significance Index: -88.3100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.7770
Cell Significance Index: -80.9100 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.8591
Cell Significance Index: -9.3600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.9317
Cell Significance Index: -71.5000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.0022
Cell Significance Index: -31.9200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -1.0209
Cell Significance Index: -72.2000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.0291
Cell Significance Index: -53.4600 - Cell Name: neural cell (CL0002319)
Fold Change: -1.0672
Cell Significance Index: -12.4500 - Cell Name: astrocyte (CL0000127)
Fold Change: -1.0695
Cell Significance Index: -12.2400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.0744
Cell Significance Index: -21.5700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.1179
Cell Significance Index: -58.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.1202
Cell Significance Index: -36.6800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.2154
Cell Significance Index: -25.8000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -1.2318
Cell Significance Index: -35.3100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.3341
Cell Significance Index: -26.3800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.3482
Cell Significance Index: -46.8500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.4039
Cell Significance Index: -49.1800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -1.5089
Cell Significance Index: -32.6000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -1.5444
Cell Significance Index: -72.0100 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -1.5728
Cell Significance Index: -11.4400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -1.5775
Cell Significance Index: -26.4000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.6236
Cell Significance Index: -52.0000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -1.6346
Cell Significance Index: -25.2900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.6829
Cell Significance Index: -35.8400 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -1.6921
Cell Significance Index: -16.1000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -1.7102
Cell Significance Index: -42.6600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2388509816
Symbol: GPM6B_HUMAN
Name: Neuronal membrane glycoprotein M6-b
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8661015
PubMed ID: 9674909
Title: Mutation analysis of the M6b gene in patients with Rett syndrome.
PubMed ID: 9674909
DOI: 10.1002/(sici)1096-8628(19980630)78:2<165::aid-ajmg13>3.0.co;2-l
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18581270
Title: Membrane glycoprotein M6B interacts with the human serotonin transporter.
PubMed ID: 18581270
PubMed ID: 21638316
Title: GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release.
PubMed ID: 21638316
DOI: 10.1002/jbmr.435
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
Sequence Information:
- Length: 265
- Mass: 28989
- Checksum: 560AB12DD2B5AE75
- Sequence:
MKPAMETAAE ENTEQSQERK GCFECCIKCL GGVPYASLVA TILCFSGVAL FCGCGHVALA GTVAILEQHF STNASDHALL SEVIQLMQYV IYGIASFFFL YGIILLAEGF YTTSAVKELH GEFKTTACGR CISGMFVFLT YVLGVAWLGV FGFSAVPVFM FYNIWSTCEV IKSPQTNGTT GVEQICVDIR QYGIIPWNAF PGKICGSALE NICNTNEFYM SYHLFIVACA GAGATVIALL IYMMATTYNY AVLKFKSRED CCTKF
Genular Protein ID: 1990514853
Symbol: Q59FD5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 280
- Mass: 30713
- Checksum: B9BC5901456216C1
- Sequence:
RSPHPSRQSP AMGCFECCIK CLGGVPYASL VATILCFSGV ALFCGCGHVA LAGTVAILEQ HFSTNASDHA LLSEVIQLMQ YVIYGIASFF FLYGIILLAE GFYTTSAVKE LHGEFKTTAC GRCISGMFVF LTYVLGVAWL GVFGFSAVPV FMFYNIWSTC EVIKSPQTNG TTGVEQICVD IRQYGIIPWN AFPGKICGSA LENICNTNEF YMSYHLFIVA CAGAGATVIA LIHFLMILSS NWAYLKDASK MQAYQDIKAK EEQELQDIQS RSKEQLNSYT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.