Details for: NRXN1

Gene ID: 9378

Symbol: NRXN1

Ensembl ID: ENSG00000179915

Description: neurexin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 587.8726
    Cell Significance Index: -149.1100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 345.1016
    Cell Significance Index: -140.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 37.7821
    Cell Significance Index: -149.0900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.0286
    Cell Significance Index: -35.0800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 14.2745
    Cell Significance Index: 342.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 13.0255
    Cell Significance Index: 800.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 9.5116
    Cell Significance Index: 3411.6400
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 9.1758
    Cell Significance Index: 128.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 7.4965
    Cell Significance Index: 504.0700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 6.0360
    Cell Significance Index: 172.2500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 4.9921
    Cell Significance Index: 85.5500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 4.7084
    Cell Significance Index: 3256.5000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 4.4572
    Cell Significance Index: 46.4300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 4.1659
    Cell Significance Index: 835.6700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.1832
    Cell Significance Index: 69.7000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.4610
    Cell Significance Index: 93.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.4068
    Cell Significance Index: 106.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.3769
    Cell Significance Index: 145.7300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 1.9287
    Cell Significance Index: 247.2500
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 1.3394
    Cell Significance Index: 17.3700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.5670
    Cell Significance Index: 29.7700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5261
    Cell Significance Index: 23.8500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4143
    Cell Significance Index: 23.2500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3652
    Cell Significance Index: 329.7100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.1202
    Cell Significance Index: 1.3100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0305
    Cell Significance Index: 0.3800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0629
    Cell Significance Index: -2.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0668
    Cell Significance Index: -125.7600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0774
    Cell Significance Index: -142.8000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0957
    Cell Significance Index: -147.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0974
    Cell Significance Index: -72.1700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1133
    Cell Significance Index: -154.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1690
    Cell Significance Index: -105.5600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1888
    Cell Significance Index: -119.9000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2076
    Cell Significance Index: -117.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2514
    Cell Significance Index: -114.1100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.2768
    Cell Significance Index: -122.3700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.3836
    Cell Significance Index: -4.4800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4098
    Cell Significance Index: -14.4000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4482
    Cell Significance Index: -128.9700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.4506
    Cell Significance Index: -73.2900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5371
    Cell Significance Index: -10.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.5496
    Cell Significance Index: -115.7500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.6047
    Cell Significance Index: -59.8200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.6439
    Cell Significance Index: -8.5900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.6986
    Cell Significance Index: -125.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.7004
    Cell Significance Index: -138.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.8711
    Cell Significance Index: -148.7500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.9040
    Cell Significance Index: -98.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.9093
    Cell Significance Index: -132.1800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.9349
    Cell Significance Index: -11.8000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0043
    Cell Significance Index: -32.8800
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -1.0331
    Cell Significance Index: -9.8300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -1.0722
    Cell Significance Index: -131.8400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.1265
    Cell Significance Index: -22.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -1.1325
    Cell Significance Index: -155.5300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -1.1448
    Cell Significance Index: -147.9000
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -1.1650
    Cell Significance Index: -8.4700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.3190
    Cell Significance Index: -42.0100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.3770
    Cell Significance Index: -160.4700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.4549
    Cell Significance Index: -166.0800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.4712
    Cell Significance Index: -153.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.4788
    Cell Significance Index: -169.4200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.4935
    Cell Significance Index: -43.0300
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.5086
    Cell Significance Index: -14.3000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.5327
    Cell Significance Index: -21.9500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.7762
    Cell Significance Index: -122.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.7857
    Cell Significance Index: -126.2900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.8679
    Cell Significance Index: -139.2100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.8757
    Cell Significance Index: -143.9400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.9144
    Cell Significance Index: -33.1000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.9432
    Cell Significance Index: -116.6600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -2.0142
    Cell Significance Index: -56.2900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -2.0882
    Cell Significance Index: -23.9000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -2.1317
    Cell Significance Index: -68.2800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -2.2276
    Cell Significance Index: -28.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.6262
    Cell Significance Index: -92.0000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -2.6824
    Cell Significance Index: -33.2700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.6929
    Cell Significance Index: -140.2700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -2.7465
    Cell Significance Index: -59.3400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -2.7577
    Cell Significance Index: -68.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -2.8404
    Cell Significance Index: -179.0200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -2.8524
    Cell Significance Index: -60.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.9309
    Cell Significance Index: -152.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -3.0995
    Cell Significance Index: -145.6800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -3.2493
    Cell Significance Index: -70.4000
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -3.4932
    Cell Significance Index: -41.7800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -3.5057
    Cell Significance Index: -121.8200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -3.6401
    Cell Significance Index: -169.7200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -3.6516
    Cell Significance Index: -91.2800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -3.8777
    Cell Significance Index: -80.9300
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -3.9656
    Cell Significance Index: -40.7700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -4.2584
    Cell Significance Index: -91.0300
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -4.3623
    Cell Significance Index: -28.3800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -4.3659
    Cell Significance Index: -85.9300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -4.3774
    Cell Significance Index: -87.2900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -4.4933
    Cell Significance Index: -112.0500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -4.7231
    Cell Significance Index: -38.9900
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -4.7307
    Cell Significance Index: -63.0600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -4.8944
    Cell Significance Index: -125.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Isoforms**: Neurexin 1 exists in two main isoforms: Neurexin 1A (NRXN1A) and Neurexin 1B (NRXN1B), which differ in their N-terminal domains. 2. **Cellular localization**: Neurexin 1 is primarily expressed in the nervous system, with high levels found in neurons, glial cells, and certain types of non-neuronal cells. 3. **Synaptic function**: Neurexin 1 plays a critical role in the formation and maintenance of synapses, regulating synaptic structure and function. 4. **Neurotransmitter regulation**: Neurexin 1 interacts with various neurotransmitters, including acetylcholine, glutamate, and GABA, to regulate synaptic transmission. **Pathways and Functions** 1. **Axon guidance**: Neurexin 1 is involved in axon guidance, regulating the formation of neural connections during development. 2. **Synaptic plasticity**: Neurexin 1 regulates synaptic plasticity, the ability of synapses to adapt and change in response to experience. 3. **Neurotransmitter release**: Neurexin 1 interacts with neurotransmitters to regulate their release and uptake at synapses. 4. **Neurodevelopmental disorders**: Neurexin 1 has been implicated in various neurodevelopmental disorders, including ASD, schizophrenia, and synaptic dysfunction. **Clinical Significance** 1. **Autism spectrum disorder (ASD)**: Neurexin 1 has been identified as a genetic risk factor for ASD, with studies suggesting a link between NRXN1 variants and the development of ASD. 2. **Schizophrenia**: Neurexin 1 has also been implicated in schizophrenia, with research suggesting a link between NRXN1 variants and the development of the disorder. 3. **Synaptic dysfunction**: Neurexin 1 plays a critical role in maintaining synaptic function, and alterations in NRXN1 expression have been linked to synaptic dysfunction in various neurological disorders. 4. **Therapeutic potential**: Neurexin 1 has been identified as a potential therapeutic target for the treatment of neurodevelopmental disorders and synaptic dysfunction. In conclusion, Neurexin 1 is a critical gene involved in the development and function of the nervous system. Its role in regulating synaptic structure and function makes it a potential therapeutic target for the treatment of neurodevelopmental disorders and synaptic dysfunction. Further research is needed to fully elucidate the mechanisms by which Neurexin 1 regulates synaptic function and to explore its therapeutic potential.

Genular Protein ID: 3239538310

Symbol: NRX1A_HUMAN

Name: Neurexin-1

UniProtKB Accession Codes:

Q9ULB1 A7KRL9 O60323 Q53TJ9 Q53TQ1 Q5HYI0 Q9C079 Q9C080 Q9C081 Q9H3M2 Q9UDM6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 2 CORUM 1 CTD 1 ChEBI 10 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 11 Ensembl 3 ExpressionAtlas 1 GO 34 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 2 RefSeq 3 SASBDB 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 18179900

Title: Disruption of neurexin 1 associated with autism spectrum disorder.

PubMed ID: 18179900

DOI: 10.1016/j.ajhg.2007.09.011

PubMed ID: 9628581

Title: Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9628581

DOI: 10.1093/dnares/5.1.31

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 11944992

Title: Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

PubMed ID: 11944992

DOI: 10.1006/geno.2002.6734

PubMed ID: 19896112

Title: CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila.

PubMed ID: 19896112

DOI: 10.1016/j.ajhg.2009.10.004

PubMed ID: 21424692

Title: Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.

PubMed ID: 21424692

DOI: 10.1007/s00439-011-0975-z

PubMed ID: 25352602

Title: Calsyntenin-3 molecular architecture and interaction with neurexin 1alpha.

PubMed ID: 25352602

DOI: 10.1074/jbc.m114.606806

PubMed ID: 22892527

Title: Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders.

PubMed ID: 22892527

DOI: 10.1038/ejhg.2012.175

Sequence Information:

  • Length: 1477
  • Mass: 161883
  • Checksum: FF845FB428B1A683
  • Sequence:
    • MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC ESEMSFQLKT 
RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSIFCAEP ATLLADTPVN DGAWHSVRIR 
RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF SGLFVGGLPP ELRAAALKLT LASVREREPF 
KGWIRDVRVN SSQVLPVDSG EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ 
AVCDCSRTGF RGKDCSQEDN NVEGLAHLMM GDQGKSKGKE EYIATFKGSE YFCYDLSQNP 
IQSSSDEITL SFKTLQRNGL MLHTGKSADY VNLALKNGAV SLVINLGSGA FEALVEPVNG 
KFNDNAWHDV KVTRNLRQHS GIGHAMVTIS VDGILTTTGY TQEDYTMLGS DDFFYVGGSP 
STADLPGSPV SNNFMGCLKE VVYKNNDVRL ELSRLAKQGD PKMKIHGVVA FKCENVATLD 
PITFETPESF ISLPKWNAKK TGSISFDFRT TEPNGLILFS HGKPRHQKDA KHPQMIKVDF 
FAIEMLDGHL YLLLDMGSGT IKIKALLKKV NDGEWYHVDF QRDGRSGTIS VNTLRTPYTA 
PGESEILDLD DELYLGGLPE NKAGLVFPTE VWTALLNYGY VGCIRDLFID GQSKDIRQMA 
EVQSTAGVKP SCSKETAKPC LSNPCKNNGM CRDGWNRYVC DCSGTGYLGR SCEREATVLS 
YDGSMFMKIQ LPVVMHTEAE DVSLRFRSQR AYGILMATTS RDSADTLRLE LDAGRVKLTV 
NLDCIRINCN SSKGPETLFA GYNLNDNEWH TVRVVRRGKS LKLTVDDQQA MTGQMAGDHT 
RLEFHNIETG IITERRYLSS VPSNFIGHLQ SLTFNGMAYI DLCKNGDIDY CELNARFGFR 
NIIADPVTFK TKSSYVALAT LQAYTSMHLF FQFKTTSLDG LILYNSGDGN DFIVVELVKG 
YLHYVFDLGN GANLIKGSSN KPLNDNQWHN VMISRDTSNL HTVKIDTKIT TQITAGARNL 
DLKSDLYIGG VAKETYKSLP KLVHAKEGFQ GCLASVDLNG RLPDLISDAL FCNGQIERGC 
EGPSTTCQED SCSNQGVCLQ QWDGFSCDCS MTSFSGPLCN DPGTTYIFSK GGGQITYKWP 
PNDRPSTRAD RLAIGFSTVQ KEAVLVRVDS SSGLGDYLEL HIHQGKIGVK FNVGTDDIAI 
EESNAIINDG KYHVVRFTRS GGNATLQVDS WPVIERYPAG RQLTIFNSQA TIIIGGKEQG 
QPFQGQLSGL YYNGLKVLNM AAENDANIAI VGNVRLVGEV PSSMTTESTA TAMQSEMSTS 
IMETTTTLAT STARRGKPPT KEPISQTTDD ILVASAECPS DDEDIDPCEP SSGGLANPTR 
AGGREPYPGS AEVIRESSST TGMVVGIVAA AALCILILLY AMYKYRNRDE GSYHVDESRN 
YISNSAQSNG AVVKEKQPSS AKSSNKNKKN KDKEYYV

Genular Protein ID: 4151448918

Symbol: NRX1B_HUMAN

Name: Neurexin I-beta

UniProtKB Accession Codes:

P58400 E7ETA5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 ComplexPortal 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 67 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 HGNC 1 HPA 1 IntAct 1 InterPro 5 KEGG 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PROSITE 1 PathwayCommons 1 PeptideAtlas 1 Pfam 2 Pharos 1 Proteomes 1 ProteomicsDB 2 Reactome 1 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 SUPFAM 1 SignaLink 1 UCSC 1 VEuPathDB 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9921901

Title: CCG repeats in cDNAs from human brain.

PubMed ID: 9921901

DOI: 10.1007/s004390050889

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18423203

Title: CASK functions as a Mg2+-independent neurexin kinase.

PubMed ID: 18423203

DOI: 10.1016/j.cell.2008.02.036

PubMed ID: 20090838

Title: beta-Neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC.

PubMed ID: 20090838

DOI: 10.1371/journal.ppat.1000726

PubMed ID: 27418511

Title: Structural basis for integration of GluD receptors within synaptic organizer complexes.

PubMed ID: 27418511

DOI: 10.1126/science.aae0104

PubMed ID: 18084303

Title: Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.

PubMed ID: 18084303

DOI: 10.1038/nsmb1350

Sequence Information:

  • Length: 472
  • Mass: 50424
  • Checksum: C86516C0EB7A2D01
  • Sequence:
    • MYQRMLRCGA ELGSPGGGGG GGGGGGAGGR LALLWIVPLT LSGLLGVAWG ASSLGAHHIH 
HFHGSSKHHS VPIAIYRSPA SLRGGHAGTT YIFSKGGGQI TYKWPPNDRP STRADRLAIG 
FSTVQKEAVL VRVDSSSGLG DYLELHIHQG KIGVKFNVGT DDIAIEESNA IINDGKYHVV 
RFTRSGGNAT LQVDSWPVIE RYPAGNNDNE RLAIARQRIP YRLGRVVDEW LLDKGRQLTI 
FNSQATIIIG GKEQGQPFQG QLSGLYYNGL KVLNMAAEND ANIAIVGNVR LVGEVPSSMT 
TESTATAMQS EMSTSIMETT TTLATSTARR GKPPTKEPIS QTTDDILVAS AECPSDDEDI 
DPCEPSSGGL ANPTRAGGRE PYPGSAEVIR ESSSTTGMVV GIVAAAALCI LILLYAMYKY 
RNRDEGSYHV DESRNYISNS AQSNGAVVKE KQPSSAKSSN KNKKNKDKEY YV

Genular Protein ID: 251393241

Symbol: H0Y568_HUMAN

Name: N/A

UniProtKB Accession Codes:

H0Y568

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 1 GeneTree 1 HGNC 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 139
  • Mass: 15303
  • Checksum: 0808FABABE954D6D
  • Sequence:
    • MDMRWHCENL QTTDDILVAS AECPSDDEDI DPCEPSSANP TRAGGREPYP GSAEVIRESS 
STTGMVVGIV AAAALCILIL LYAMYKYRNR DEGSYHVDES RNYISNSAQS NGAVVKEKQP 
SSAKSSNKNK KNKDKEYYV

Genular Protein ID: 2927392295

Symbol: H7BYC7_HUMAN

Name: N/A

UniProtKB Accession Codes:

H7BYC7

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 2 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 142
  • Mass: 15530
  • Checksum: 70FAE8135BEB82BE
  • Sequence:
    • MDMRWHCENL QTTDDILVAS AECPSDDEDI DPCEPSSGGL ANPTRAGGRE PYPGSAEVIR 
ESSSTTGMVV GIVAAAALCI LILLYAMYKY RNRDEGSYHV DESRNYISNS AQSNGAVVKE 
KQPSSAKSSN KNKKNKDKEY YV

Genular Protein ID: 3647841494

Symbol: E7ERL8_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7ERL8

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 35 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1507
  • Mass: 165446
  • Checksum: D1716CC37589747E
  • Sequence:
    • MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC ESEMSFQLKT 
RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSIFCAEP ATLLADTPVN DGAWHSVRIR 
RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF SGLFVGGLPP ELRAAALKLT LASVREREPF 
KGWIRDVRVN SSQVLPVDSG EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ 
AVCDCSRTGF RGKDCSQEDN NVEGLAHLMM GDQGKSKGKE EYIATFKGSE YFCYDLSQNP 
IQSSSDEITL SFKTLQRNGL MLHTGKSADY VNLALKNGAV SLVINLGSGA FEALVEPVNG 
KFNDNAWHDV KVTRNLRQHS GIGHAMVTIS VDGILTTTGY TQEDYTMLGS DDFFYVGGSP 
STADLPGSPV SNNFMGCLKE VVYKNNDVRL ELSRLAKQGD PKMKIHGVVA FKCENVATLD 
PITFETPESF ISLPKWNAKK TGSISFDFRT TEPNGLILFS HGKPRHQKDA KHPQMIKVDF 
FAIEMLDGHL YLLLDMGSGT IKIKALLKKV NDGEWYHVDF QRDGRSGTIS VNTLRTPYTA 
PGESEILDLD DELYLGGLPE NKAGLVFPTE VWTALLNYGY VGCIRDLFID GQSKDIRQMA 
EVQSTAGVKP SCSKETAKPC LSNPCKNNGM CRDGWNRYVC DCSGTGYLGR SCEREATVLS 
YDGSMFMKIQ LPVVMHTEAE DVSLRFRSQR AYGILMATTS RDSADTLRLE LDAGRVKLTV 
NLDCIRINCN SSKGPETLFA GYNLNDNEWH TVRVVRRGKS LKLTVDDQQA MTGQMAGDHT 
RLEFHNIETG IITERRYLSS VPSNFIGHLQ SLTFNGMAYI DLCKNGDIDY CELNARFGFR 
NIIADPVTFK TKSSYVALAT LQAYTSMHLF FQFKTTSLDG LILYNSGDGN DFIVVELVKG 
YLHYVFDLGN GANLIKGSSN KPLNDNQWHN VMISRDTSNL HTVKIDTKIT TQITAGARNL 
DLKSDLYIGG VAKETYKSLP KLVHAKEGFQ GCLASVDLNG RLPDLISDAL FCNGQIERGC 
EGPSTTCQED SCSNQGVCLQ QWDGFSCDCS MTSFSGPLCN DPGTTYIFSK GGGQITYKWP 
PNDRPSTRAD RLAIGFSTVQ KEAVLVRVDS SSGLGDYLEL HIHQGKIGVK FNVGTDDIAI 
EESNAIINDG KYHVVRFTRS GGNATLQVDS WPVIERYPAG NNDNERLAIA RQRIPYRLGR 
VVDEWLLDKG RQLTIFNSQA TIIIGGKEQG QPFQGQLSGL YYNGLKVLNM AAENDANIAI 
VGNVRLVGEV PSSMTTESTA TAMQSEMSTS IMETTTTLAT STARRGKPPT KEPISQTTDD 
ILVASAECPS DDEDIDPCEP SSGGLANPTR AGGREPYPGS AEVIRESSST TGMVVGIVAA 
AALCILILLY AMYKYRNRDE GSYHVDESRN YISNSAQSNG AVVKEKQPSS AKSSNKNKKN 
KDKEYYV

Genular Protein ID: 1092661161

Symbol: A0A0D9SEQ7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0D9SEQ7

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 277
  • Mass: 30241
  • Checksum: AD1598E42DBA2AB9
  • Sequence:
    • MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC ESEMSFQLKT 
RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSIFCAEP ATLLADTPVN DGAWHSVRIR 
RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF SGLFVGGLPP ELRAAALKLT LASVREREPF 
KGWIRDVRVN SSQVLPVDSG EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ 
AVCDCSRTGF RGKDCSQDNN VEGLAHLMMG DQGKSKD

Genular Protein ID: 1918607816

Symbol: E7EQN4_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EQN4

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 278
  • Mass: 30371
  • Checksum: FDDF6EC31CAB06BD
  • Sequence:
    • MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC ESEMSFQLKT 
RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSIFCAEP ATLLADTPVN DGAWHSVRIR 
RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF SGLFVGGLPP ELRAAALKLT LASVREREPF 
KGWIRDVRVN SSQVLPVDSG EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ 
AVCDCSRTGF RGKDCSQEDN NVEGLAHLMM GDQGKSKD

Genular Protein ID: 3781549319

Symbol: A0A1D5RMU6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1D5RMU6

Database IDs:

ARBA 10 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 1499
  • Mass: 164655
  • Checksum: F8481191C84C9CD7
  • Sequence:
    • MGTALLQRGG CFLLCLSLLL LGCWAELGSG LEFPGAEGQW TRFPKWNACC ESEMSFQLKT 
RSARGLVLYF DDEGFCDFLE LILTRGGRLQ LSFSIFCAEP ATLLADTPVN DGAWHSVRIR 
RQFRNTTLFI DQVEAKWVEV KSKRRDMTVF SGLFVGGLPP ELRAAALKLT LASVREREPF 
KGWIRDVRVN SSQVLPVDSG EVKLDDEPPN SGGGSPCEAG EEGEGGVCLN GGVCSVVDDQ 
AVCDCSRTGF RGKDCSQEDN NVEGLAHLMM GDQGKSKGKE EYIATFKGSE YFCYDLSQNP 
IQSSSDEITL SFKTLQRNGL MLHTGKSADY VNLALKNGAV SLVINLGSGA FEALVEPVNG 
KFNDNAWHDV KVTRNLRQVT ISVDGILTTT GYTQEDYTML GSDDFFYVGG SPSTADLPGS 
PVSNNFMGCL KEVVYKNNDV RLELSRLAKQ GDPKMKIHGV VAFKCENVAT LDPITFETPE 
SFISLPKWNA KKTGSISFDF RTTEPNGLIL FSHGKPRHQK DAKHPQMIKV DFFAIEMLDG 
HLYLLLDMGS GTIKIKALLK KVNDGEWYHV DFQRDGRSGT ISVNTLRTPY TAPGESEILD 
LDDELYLGGL PENKAGLVFP TEVWTALLNY GYVGCIRDLF IDGQSKDIRQ MAEVQSTAGV 
KPSCSKETAK PCLSNPCKNN GMCRDGWNRY VCDCSGTGYL GRSCEREATV LSYDGSMFMK 
IQLPVVMHTE AEDVSLRFRS QRAYGILMAT TSRDSADTLR LELDAGRVKL TVNLDCIRIN 
CNSSKGPETL FAGYNLNDNE WHTVRVVRRG KSLKLTVDDQ QAMTGQMAGD HTRLEFHNIE 
TGIITERRYL SSVPSNFIGH LQSLTFNGMA YIDLCKNGDI DYCELNARFG FRNIIADPVT 
FKTKSSYVAL ATLQAYTSMH LFFQFKTTSL DGLILYNSGD GNDFIVVELV KGYLHYVFDL 
GNGANLIKGS SNKPLNDNQW HNVMISRDTS NLHTVKIDTK ITTQITAGAR NLDLKSDLYI 
GGVAKETYKS LPKLVHAKEG FQGCLASVDL NGRLPDLISD ALFCNGQIER GCEGPSTTCQ 
EDSCSNQGVC LQQWDGFSCD CSMTSFSGPL CNDPGTTYIF SKGGGQITYK WPPNDRPSTR 
ADRLAIGFST VQKEAVLVRV DSSSGLGDYL ELHIHQGKIG VKFNVGTDDI AIEESNAIIN 
DGKYHVVRFT RSGGNATLQV DSWPVIERYP AGNNDNERLA IARQRIPYRL GRVVDEWLLD 
KGRQLTIFNS QATIIIGGKE QGQPFQGQLS GLYYNGLKVL NMAAENDANI AIVGNVRLVG 
EVPSSMTTES TATAMQSEMS TSIMETTTTL ATSTARRGKP PTKEPISQTT DDILVASAEC 
PSDDEDIDPC EPSSGGLANP TRAGGREPYP GSAEVIRESS STTGMVVGIV AAAALCILIL 
LYAMYKYRNR DEGSYHVDES RNYISNSAQS NGAVVKEKQP SSAKSSNKNK KNKDKEYYV

Genular Protein ID: 2068425397

Symbol: A0A0D9SEM5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0D9SEM5

Database IDs:

ARBA 8 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 469
  • Mass: 50196
  • Checksum: 9BB86B15015C9DD1
  • Sequence:
    • MYQRMLRCGA ELGSPGGGGG GGGGGGAGGR LALLWIVPLT LSGLLGVAWG ASSLGAHHIH 
HFHGSSKHHS VPIAIYRSPA SLRGGHAGTT YIFSKGGGQI TYKWPPNDRP STRADRLAIG 
FSTVQKEAVL VRVDSSSGLG DYLELHIHQG KIGVKFNVGT DDIAIEESNA IINDGKYHVV 
RFTRSGGNAT LQVDSWPVIE RYPAGNNDNE RLAIARQRIP YRLGRVVDEW LLDKGRQLTI 
FNSQATIIIG GKEQGQPFQG QLSGLYYNGL KVLNMAAEND ANIAIVGNVR LVGEVPSSMT 
TESTATAMQS EMSTSIMETT TTLATSTARR GKPPTKEPIS QTTDDILVAS AECPSDDEDI 
DPCEPSSANP TRAGGREPYP GSAEVIRESS STTGMVVGIV AAAALCILIL LYAMYKYRNR 
DEGSYHVDES RNYISNSAQS NGAVVKEKQP SSAKSSNKNK KNKDKEYYV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.