Details for: NRCAM

Gene ID: 4897

Symbol: NRCAM

Ensembl ID: ENSG00000091129

Description: neuronal cell adhesion molecule

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 8.1437
    Cell Significance Index: 456.9800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 5.2533
    Cell Significance Index: 73.4600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.2271
    Cell Significance Index: 351.4700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.2356
    Cell Significance Index: 120.8700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 4.1804
    Cell Significance Index: 51.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 3.9003
    Cell Significance Index: 93.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.8382
    Cell Significance Index: 1376.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 3.6959
    Cell Significance Index: 5025.4200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.5139
    Cell Significance Index: 215.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.4885
    Cell Significance Index: 699.7800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.9356
    Cell Significance Index: 78.6600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.8086
    Cell Significance Index: 1942.5200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 2.0813
    Cell Significance Index: 92.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.8869
    Cell Significance Index: 359.0900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.8261
    Cell Significance Index: 69.1500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 1.1676
    Cell Significance Index: 9.0000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 1.1320
    Cell Significance Index: 15.1000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 1.0521
    Cell Significance Index: 10.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.9950
    Cell Significance Index: 98.4300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.9486
    Cell Significance Index: 20.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.5444
    Cell Significance Index: 9.3300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3707
    Cell Significance Index: 60.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2742
    Cell Significance Index: 422.1400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.1203
    Cell Significance Index: 1.5000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1183
    Cell Significance Index: 20.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0894
    Cell Significance Index: 168.3900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0138
    Cell Significance Index: 7.5200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0065
    Cell Significance Index: 0.2300
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.0062
    Cell Significance Index: -0.0800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0121
    Cell Significance Index: -7.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0189
    Cell Significance Index: -14.0300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0320
    Cell Significance Index: -0.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0437
    Cell Significance Index: -1.2600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0444
    Cell Significance Index: -81.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0915
    Cell Significance Index: -51.5800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0964
    Cell Significance Index: -70.6700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1001
    Cell Significance Index: -63.5600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.1091
    Cell Significance Index: -11.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1290
    Cell Significance Index: -97.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1535
    Cell Significance Index: -30.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1606
    Cell Significance Index: -7.2800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1829
    Cell Significance Index: -80.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1851
    Cell Significance Index: -84.0100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2058
    Cell Significance Index: -43.3600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.2065
    Cell Significance Index: -1.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2590
    Cell Significance Index: -74.5100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.3328
    Cell Significance Index: -4.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3528
    Cell Significance Index: -63.6000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3655
    Cell Significance Index: -3.9800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.3727
    Cell Significance Index: -54.1800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5397
    Cell Significance Index: -17.6700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.5442
    Cell Significance Index: -9.4100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5474
    Cell Significance Index: -55.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5777
    Cell Significance Index: -30.3300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.5825
    Cell Significance Index: -80.0000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5899
    Cell Significance Index: -12.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.6067
    Cell Significance Index: -74.6000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6442
    Cell Significance Index: -20.5200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.6959
    Cell Significance Index: -89.9000
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.6969
    Cell Significance Index: -8.1300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.7196
    Cell Significance Index: -92.2500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.7543
    Cell Significance Index: -21.0800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7597
    Cell Significance Index: -88.5300
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7970
    Cell Significance Index: -15.7600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7985
    Cell Significance Index: -83.1400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.8051
    Cell Significance Index: -94.9500
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.8057
    Cell Significance Index: -6.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.8304
    Cell Significance Index: -95.1400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.8332
    Cell Significance Index: -95.1100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.8348
    Cell Significance Index: -16.7600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9282
    Cell Significance Index: -19.7000
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.0354
    Cell Significance Index: -9.8200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.0666
    Cell Significance Index: -64.0300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.0883
    Cell Significance Index: -86.1900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -1.1219
    Cell Significance Index: -12.8400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.1482
    Cell Significance Index: -36.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.1681
    Cell Significance Index: -89.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.2035
    Cell Significance Index: -85.1200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.2070
    Cell Significance Index: -89.9600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.3534
    Cell Significance Index: -29.2400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.3885
    Cell Significance Index: -35.6900
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -1.4074
    Cell Significance Index: -17.0600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.4472
    Cell Significance Index: -75.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.4549
    Cell Significance Index: -89.2000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.4801
    Cell Significance Index: -51.8500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.4907
    Cell Significance Index: -96.1800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.5833
    Cell Significance Index: -82.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.5931
    Cell Significance Index: -100.4100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.5953
    Cell Significance Index: -39.8000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.6009
    Cell Significance Index: -50.6400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.7164
    Cell Significance Index: -24.5800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.7699
    Cell Significance Index: -83.1900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -1.8102
    Cell Significance Index: -45.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -1.8711
    Cell Significance Index: -49.9600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.9259
    Cell Significance Index: -40.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.9604
    Cell Significance Index: -53.3600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -2.0548
    Cell Significance Index: -25.9300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -2.1425
    Cell Significance Index: -99.9000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.3766
    Cell Significance Index: -87.2500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -2.5275
    Cell Significance Index: -87.8300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** NRCAM is a large transmembrane glycoprotein consisting of five extracellular immunoglobulin-like domains, three fibronectin-type III domains, and a single transmembrane domain. It is expressed on the surface of neurons and several other cell types, including glial cells, during development and in adulthood. NRCAM's unique structure allows it to interact with multiple ligands, including L1, axon guidance-related molecules (e.g., semaphorins), and other adhesion molecules. **Pathways and Functions:** NRCAM's functions can be broadly categorized into three main areas: 1. **Cell-cell adhesion and migration**: NRCAM interacts with L1 and other adhesion molecules to mediate cell-cell interactions, influencing neuronal migration, axon guidance, and synapse formation. 2. **Axon guidance and extension**: NRCAM's interaction with semaphorins and other axon guidance-related molecules regulates axon extension, branching, and targeting. 3. **Neuronal differentiation and synaptogenesis**: NRCAM's presence is required for the differentiation of neurons and the formation of synapses, which are critical for neuronal function and behavior. **Clinical Significance:** Dysregulation of NRCAM has been implicated in various neurological disorders, including: 1. **Autism spectrum disorder (ASD)**: Studies have shown that NRCAM mutations or altered expression are associated with ASD, suggesting a role for NRCAM in neuronal function and behavior. 2. **Schizophrenia**: NRCAM has been linked to schizophrenia, with altered expression and function observed in post-mortem brain tissue and in vivo studies. 3. **Alzheimer's disease**: NRCAM's role in synapse formation and maintenance has been implicated in Alzheimer's disease, with altered expression and function observed in affected brains. In addition to its role in neurological disorders, NRCAM's dysregulation has been linked to other diseases, including cancer and cardiovascular disease. Further research is needed to fully understand the complex mechanisms by which NRCAM regulates neural development and function, and to explore its potential as a therapeutic target for these diseases. **Conclusion:** In conclusion, NRCAM is a critical regulator of neural development, migration, and function. Its dysregulation has been implicated in various neurological disorders, highlighting the need for further research into the mechanisms by which NRCAM regulates neural function. As our understanding of NRCAM's role in disease progression and development continues to evolve, it is likely that this molecule will emerge as a promising therapeutic target for the treatment of these complex and devastating disorders.

Genular Protein ID: 2708622328

Symbol: NRCAM_HUMAN

Name: Neuronal cell adhesion molecule

UniProtKB Accession Codes:

Q92823 A4D0S3 E9PDA4 O15051 O15179 Q14BM2 Q9UHI3 Q9UHI4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 3 RefSeq 8 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8812479

Title: Characterization of a highly conserved human homolog to the chicken neural cell surface protein Bravo/Nr-CAM that maps to chromosome band 7q31.

PubMed ID: 8812479

DOI: 10.1006/geno.1996.0385

PubMed ID: 11483367

Title: The complete sequence of the human locus for NgCAM-related cell adhesion molecule reveals a novel alternative exon in chick and man and conserved genomic organization for the L1 subfamily.

PubMed ID: 11483367

DOI: 10.1016/s0378-1119(01)00493-0

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 23897819

Title: Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling.

PubMed ID: 23897819

DOI: 10.1074/jbc.m112.446138

PubMed ID: 35108495

Title: Bi-allelic variants in neuronal cell adhesion molecule cause a neurodevelopmental disorder characterized by developmental delay, hypotonia, neuropathy/spasticity.

PubMed ID: 35108495

DOI: 10.1016/j.ajhg.2022.01.004

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1304
  • Mass: 143890
  • Checksum: 1F2698BC7DB5C363
  • Sequence:
    • MQLKIMPKKK RLSAGRVPLI LFLCQMISAL EVPLDPKLLE DLVQPPTITQ QSPKDYIIDP 
RENIVIQCEA KGKPPPSFSW TRNGTHFDID KDPLVTMKPG TGTLIINIMS EGKAETYEGV 
YQCTARNERG AAVSNNIVVR PSRSPLWTKE KLEPITLQSG QSLVLPCRPP IGLPPPIIFW 
MDNSFQRLPQ SERVSQGLNG DLYFSNVLPE DTREDYICYA RFNHTQTIQQ KQPISVKVIS 
VDELNDTIAA NLSDTEFYGA KSSRERPPTF LTPEGNASNK EELRGNVLSL ECIAEGLPTP 
IIYWAKEDGM LPKNRTVYKN FEKTLQIIHV SEADSGNYQC IAKNALGAIH HTISVRVKAA 
PYWITAPQNL VLSPGEDGTL ICRANGNPKP RISWLTNGVP IEIAPDDPSR KIDGDTIIFS 
NVQERSSAVY QCNASNEYGY LLANAFVNVL AEPPRILTPA NTLYQVIANR PALLDCAFFG 
SPLPTIEWFK GAKGSALHED IYVLHENGTL EIPVAQKDST GTYTCVARNK LGMAKNEVHL 
EIKDPTWIVK QPEYAVVQRG SMVSFECKVK HDHTLSLTVL WLKDNRELPS DERFTVDKDH 
LVVADVSDDD SGTYTCVANT TLDSVSASAV LSVVAPTPTP APVYDVPNPP FDLELTDQLD 
KSVQLSWTPG DDNNSPITKF IIEYEDAMHK PGLWHHQTEV SGTQTTAQLK LSPYVNYSFR 
VMAVNSIGKS LPSEASEQYL TKASEPDKNP TAVEGLGSEP DNLVITWKPL NGFESNGPGL 
QYKVSWRQKD GDDEWTSVVV ANVSKYIVSG TPTFVPYLIK VQALNDMGFA PEPAVVMGHS 
GEDLPMVAPG NVRVNVVNST LAEVHWDPVP LKSIRGHLQG YRIYYWKTQS SSKRNRRHIE 
KKILTFQGSK THGMLPGLEP FSHYTLNVRV VNGKGEGPAS PDRVFNTPEG VPSAPSSLKI 
VNPTLDSLTL EWDPPSHPNG ILTEYTLKYQ PINSTHELGP LVDLKIPANK TRWTLKNLNF 
STRYKFYFYA QTSAGSGSQI TEEAVTTVDE AGILPPDVGA GKVQAVNPRI SNLTAAAAET 
YANISWEYEG PEHVNFYVEY GVAGSKEEWR KEIVNGSRSF FGLKGLMPGT AYKVRVGAVG 
DSGFVSSEDV FETGPAMASR QVDIATQGWF IGLMCAVALL ILILLIVCFI RRNKGGKYPV 
KEKEDAHADP EIQPMKEDDG TFGEYSDAED HKPLKKGSRT PSDRTVKKED SDDSLVDYGE 
GVNGQFNEDG SFIGQYSGKK EKEPAEGNES SEAPSPVNAM NSFV

Genular Protein ID: 1249942222

Symbol: B7Z670_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z670

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 3 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 1153
  • Mass: 127589
  • Checksum: 18D09613A77B6FD5
  • Sequence:
    • MQLKIMPKKK RLSAGRVPLI LFLCQMISAL EVPLDPKLLE DLVQPPTITQ QSPKDYIIDP 
RENIVIQCEA KGKPPPSFSW TRNGTHFDID KDPLVTMKPG TGTLIINIMS EGKAETYEGV 
YQCTARNERG AAVSNNIVVR PSRSPLWTKE KLEPITLQSG QSLVLPCRPP IGLPPPIIFW 
MDNSFQRLPQ SERVSQGLNG DLYFSNVLPE DTREDYICYA RFNHTQTIQQ KQPISVKVIS 
VDELNDTIAA NLSDTEFYGA KSSRERPPTF LTPEGNASNK EELRGNVLSL ECIAEGLPTP 
IIYWAKEDGM LPKNRTVYKN FEKTLQIIHV SEADSGNYQC IAKNALGAIH HTISVRVKAA 
PYWITAPQNL VLSPGEDGTL ICRANGNPKP RISWLTNGVP IEIAPDDPSR KIDGDTIIFS 
NVQERSSAVY QCNASNEYGY LLANAFVNVL AEPPRILTPA NTLYQVIANR PALLDCAFFG 
SPLPTIEWFK GAKGSALHED IYVLHENGTL EIPVAQKDST GTYTCVARNK LGMAKNEVHL 
EIKDATWIVK QPEYAVVQRG SMVSFECKVK HDHTLSLTVL WLKDNRELPS DERFTVDKDH 
LVVADVSDDD SGTYTCVANT TLDSVSASAV LSVVAPTPTP APVYDVPNPP FDLELTDQLD 
KSVQLSWTPG DDNNSPITKF IIEYEDAMHK PGLWHHQTEV SGTQTTAQLK LSPYVNYSFR 
VMAVNSIGKS LPSEASEQYL TKASEPDKNP TAVEGLGSEP DNLVITWKPL NGFESNGPGL 
QYKVSWRQKD GDDEWTSVVV ANVSKYIVSG TPTFVPYLIK VQALNDMGFA PEPAVVMGHS 
GEDLPMVAPG NVRVNVVNST LAEVHWDPVP LKSIRGHLQG YRIYYWKTQS SSKRNRRHIE 
KKILTFQGSK THGMLPGLEP FSHYTLNVRV VNGKGEGPAS PDRVFNTPEG VPSAPSSLKI 
VNPTLDSLTL EWDPPSHPNG ILTEYTLKYQ PINSTHELGP LVDLKIPANK TRWTLKNLNF 
STRYKFYFYA QTSAGSGSQI TEEAVTTVDE AGILPPDVGA GKAMASRQVD IATQGWFIGL 
MCAVALLILI LLIVCFIRRN KGGKYPVKEK EDAHADPEIQ PMKEDDGTFG EYSDAEDHKP 
LKKGSRTPSD RTV

Genular Protein ID: 3002273647

Symbol: C9JYY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9JYY6

Database IDs:

ARBA 4 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 10 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 2 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 3 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 1211
  • Mass: 133814
  • Checksum: C0C8D1A6DA566DBE
  • Sequence:
    • MQLKIMPKKK RLSAGRVPLI LFLCQMISAL EVPLDPKLLE DLVQPPTITQ QSPKDYIIDP 
RENIVIQCEA KGKPPPSFSW TRNGTHFDID KDPLVTMKPG TGTLIINIMS EGKAETYEGV 
YQCTARNERG AAVSNNIVVR PSRSPLWTKE KLEPITLQSG QSLVLPCRPP IGLPPPIIFW 
MDNSFQRLPQ SERVSQGLNG DLYFSNVLPE DTREDYICYA RFNHTQTIQQ KQPISVKVIS 
VDELNDTIAA NLSDTEFYGA KSSRERPPTF LTPEGNASNK EELRGNVLSL ECIAEGLPTP 
IIYWAKEDGM LPKNRTVYKN FEKTLQIIHV SEADSGNYQC IAKNALGAIH HTISVRVKAA 
PYWITAPQNL VLSPGEDGTL ICRANGNPKP RISWLTNGVP IEIAPDDPSR KIDGDTIIFS 
NVQERSSAVY QCNASNEYGY LLANAFVNVL AEPPRILTPA NTLYQVIANR PALLDCAFFG 
SPLPTIEWFK GAKGSALHED IYVLHENGTL EIPVAQKDST GTYTCVARNK LGMAKNEVHL 
EIKDPTWIVK QPEYAVVQRG SMVSFECKVK HDHTLSLTVL WLKDNRELPS DERFTVDKDH 
LVVADVSDDD SGTYTCVANT TLDSVSASAV LSVVAPTPTP APVYDVPNPP FDLELTDQLD 
KSVQLSWTPG DDNNSPITKF IIEYEDAMHK PGLWHHQTEV SGTQTTAQLK LSPYVNYSFR 
VMAVNSIGKS LPSEASEQYL TKASEPDKNP TAVEGLGSEP DNLVITWKPL NGFESNGPGL 
QYKVSWRQKD GDDEWTSVVV ANVSKYIVSG TPTFVPYLIK VQALNDMGFA PEPAVVMGHS 
GEDLPMVAPG NVRVNVVNST LAEVHWDPVP LKSIRGHLQG YRIYYWKTQS SSKRNRRHIE 
KKILTFQGSK THGMLPGLEP FSHYTLNVRV VNGKGEGPAS PDRVFNTPEG VPSAPSSLKI 
VNPTLDSLTL EWDPPSHPNG ILTEYTLKYQ PINSTHELGP LVDLKIPANK TRWTLKNLNF 
STRYKFYFYA QTSAGSGSQI TEEAVTTVDE AGILPPDVGA GKAMASRQVD IATQGWFIGL 
MCAVALLILI LLIVCFIRRN KGGKYPVKEK EDAHADPEIQ PMKEDDGTFG EYSDAEDHKP 
LKKGSRTPSD RTVKKEDSDD SLVDYGEGVN GQFNEDGSFI GQYSGKKEKE PAEGNESSEA 
PSPVNAMNSF V

Genular Protein ID: 73848031

Symbol: Q14CA1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q14CA1

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 1 InterPro 10 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 3 SMART 3 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1180
  • Mass: 130642
  • Checksum: 3E44CDD67FF3902E
  • Sequence:
    • MQLKIMPKKK RLSAGRVPLI LFLCQMISAL EVPLDPKLLE DLVQPPTITQ QSPKDYIIDP 
RENIVIQCEA KGKPPPSFSW TRNGTHFDID KDPLVTMKPG TGTLIINIMS EGKAETYEGV 
YQCTARNERG AAVSNNIVVR PSRSPLWTKE KLEPITLQSG QSLVLPCRPP IGLPPPIIFW 
MDNSFQRLPQ SERVSQGLNG DLYFSNVLPE DTREDYICYA RFNHTQTIQQ KQPISVKVIS 
AKSSRERPPT FLTPEGNASN KEELRGNVLS LECIAEGLPT PIIYWAKEDG MLPKNRTVYK 
NFEKTLQIIH VSEADSGNYQ CIAKNALGAI HHTISVRVKA APYWITAPQN LVLSPGEDGT 
LICRANGNPK PRISWLTNGV PIEIAPDDPS RKIDGDTIIF SNVQERSSAV YQCNASNEYG 
YLLANAFVNV LAEPPRILTP ANTLYQVIAN RPALLDCAFF GSPLPTIEWF KGAKGSALHE 
DIYVLHENGT LEIPVAQKDS TGTYTCVARN KLGMAKNEVH LEIKDATWIV KQPEYAVVQR 
GSMVSFECKV KHDHTLSLTV LWLKDNRELP SDERFTVDKD HLVVADVSDD DSGTYTCVAN 
TTLDSVSASA VLSVVAPTPT PAPVYDVPNP PFDLELTDQL DKSVQLSWTP GDDNNSPITK 
FIIEYEDAMH KPGLWHHQTE VSGTQTTAQL KLSPYVNYSF RVMAVNSIGK SLPSEASEQY 
LTKASEPDKN PTAVEGLGSE PDNLVITWKP LNGFESNGPG LQYKVSWRQK DGDDEWTSVV 
VANVSKYIVS GTPTFVPYLI KVQALNDMGF APEPAVVMGH SGEDLPMVAP GNVRVNVVNS 
TLAEVHWDPV PLKSIRGHLQ GYRIYYWKTQ SSSKRNRRHI EKKILTFQGS KTHGMLPGLE 
PFSHYTLNVR VVNGKGEGPA SPDRVFNTPE GVPSAPSSLK IVNPTLDSLT LEWDPPSHPN 
GILTEYTLKY QPINSTHELG PLVDLKIPAN KTRWTLKNLN FSTRYKFYFY AQTSAGSGSQ 
ITEEAVTTVD EAMASRQVDI ATQGWFIGLM CAVALLILIL LIVCFIRRNK GGKYPVKEKE 
DAHADPEIQP MKEDDGTFGE YSDAEDHKPL KKGSRTPSDR TVKKEDSDDS LVDYGEGVNG 
QFNEDGSFIG QYSGKKEKEP AEGNESSEAP SPVNAMNSFV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.