Details for: NEO1

Gene ID: 4756

Symbol: NEO1

Ensembl ID: ENSG00000067141

Description: neogenin 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 403.3554
    Cell Significance Index: -62.7400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 248.6956
    Cell Significance Index: -63.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 132.0631
    Cell Significance Index: -62.3500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 125.8563
    Cell Significance Index: -51.1300
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 93.2011
    Cell Significance Index: -62.5400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 53.3861
    Cell Significance Index: -50.9700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 50.9994
    Cell Significance Index: -62.8800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.6332
    Cell Significance Index: -63.3100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 15.9755
    Cell Significance Index: -63.0400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 13.0175
    Cell Significance Index: -28.4900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 3.9052
    Cell Significance Index: 177.0100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.3364
    Cell Significance Index: 85.7600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.4310
    Cell Significance Index: 136.4200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.4105
    Cell Significance Index: 483.5500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.1254
    Cell Significance Index: 53.1300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.0502
    Cell Significance Index: 59.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 2.0467
    Cell Significance Index: 137.6200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.9055
    Cell Significance Index: 207.2600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.7567
    Cell Significance Index: 1586.1600
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.1773
    Cell Significance Index: 17.6400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0080
    Cell Significance Index: 697.1800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0037
    Cell Significance Index: 28.0500
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.9797
    Cell Significance Index: 13.7000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9102
    Cell Significance Index: 326.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7547
    Cell Significance Index: 33.3800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7417
    Cell Significance Index: 147.1900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7413
    Cell Significance Index: 28.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4094
    Cell Significance Index: 31.4200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3804
    Cell Significance Index: 61.8700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3367
    Cell Significance Index: 7.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.3259
    Cell Significance Index: 9.3000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2848
    Cell Significance Index: 125.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2696
    Cell Significance Index: 4.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2335
    Cell Significance Index: 44.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2268
    Cell Significance Index: 144.0200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.2258
    Cell Significance Index: 347.6200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2200
    Cell Significance Index: 7.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2031
    Cell Significance Index: 382.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1960
    Cell Significance Index: 12.0500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.1731
    Cell Significance Index: 3.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1670
    Cell Significance Index: 307.9200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1649
    Cell Significance Index: 90.0300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0795
    Cell Significance Index: 14.3300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0777
    Cell Significance Index: 105.6500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0545
    Cell Significance Index: 1.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0413
    Cell Significance Index: 18.7400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0077
    Cell Significance Index: 0.7600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0195
    Cell Significance Index: -2.8300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0452
    Cell Significance Index: -33.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0544
    Cell Significance Index: -6.6900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0596
    Cell Significance Index: -33.6200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0627
    Cell Significance Index: -39.1600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0655
    Cell Significance Index: -47.9900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0774
    Cell Significance Index: -58.5900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0849
    Cell Significance Index: -10.8800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0935
    Cell Significance Index: -15.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1336
    Cell Significance Index: -18.3500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1801
    Cell Significance Index: -51.8200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1984
    Cell Significance Index: -9.2500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2237
    Cell Significance Index: -47.1100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2542
    Cell Significance Index: -29.6200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2545
    Cell Significance Index: -13.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3052
    Cell Significance Index: -31.7800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3210
    Cell Significance Index: -20.2300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3240
    Cell Significance Index: -4.4200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3509
    Cell Significance Index: -40.2000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4127
    Cell Significance Index: -53.3200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.4173
    Cell Significance Index: -9.0400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.4349
    Cell Significance Index: -44.4300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4783
    Cell Significance Index: -33.8300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4971
    Cell Significance Index: -12.1300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5367
    Cell Significance Index: -63.2900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.5416
    Cell Significance Index: -61.8200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5461
    Cell Significance Index: -17.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.6888
    Cell Significance Index: -32.3800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.6949
    Cell Significance Index: -7.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7110
    Cell Significance Index: -43.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7274
    Cell Significance Index: -57.6100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.7275
    Cell Significance Index: -37.7900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.7278
    Cell Significance Index: -54.2400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.7840
    Cell Significance Index: -13.5600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.8104
    Cell Significance Index: -28.1600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.8231
    Cell Significance Index: -19.7400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.9714
    Cell Significance Index: -62.6700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.0322
    Cell Significance Index: -17.2800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0330
    Cell Significance Index: -33.8200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.0374
    Cell Significance Index: -33.0400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.0792
    Cell Significance Index: -21.3400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0849
    Cell Significance Index: -56.9600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.1157
    Cell Significance Index: -24.4300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.1588
    Cell Significance Index: -14.4500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -1.1751
    Cell Significance Index: -18.1800
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -1.1976
    Cell Significance Index: -12.8400
  • Cell Name: granule cell (CL0000120)
    Fold Change: -1.1977
    Cell Significance Index: -13.6400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -1.2908
    Cell Significance Index: -18.5000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.3079
    Cell Significance Index: -45.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -1.3268
    Cell Significance Index: -36.1200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.4559
    Cell Significance Index: -30.9000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.4988
    Cell Significance Index: -30.0900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -1.5174
    Cell Significance Index: -65.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Surface Protein:** NEO1 is a cell surface protein, primarily localized to the plasma membrane, where it interacts with various ligands and receptors, influencing cell-cell adhesion, signaling, and migration. 2. **Multifunctional:** NEO1 exhibits multiple functions, including regulation of axon guidance, neuronal migration, cell-cell adhesion, and immune response modulation. 3. **Signaling Receptor Activity:** NEO1 acts as a co-receptor for Netrin-1, a key ligand in axon guidance and neuronal migration. 4. **Diverse Ligand Interactions:** NEO1 interacts with various ligands, including Netrin-1, Bmp receptors, and cadherins, demonstrating its versatility in mediating different cellular responses. **Pathways and Functions:** 1. **Axonal Growth Cone and Guidance:** NEO1 plays a critical role in axonal growth cone formation and guidance, influencing neuronal migration and axon outgrowth. 2. **Cell-Cell Adhesion:** NEO1 mediates cell-cell adhesion through its interactions with cadherins and other adhesion molecules, regulating tissue architecture and immune response. 3. **Immune Regulation:** NEO1 modulates immune responses by interacting with immune cells, such as macrophages and T-cells, influencing inflammation and immune homeostasis. 4. **Neuronal Migration and Development:** NEO1 is essential for neuronal migration, axon guidance, and development, highlighting its importance in nervous system formation and function. **Clinical Significance:** 1. **Neurological Disorders:** Alterations in NEO1 expression have been linked to neurological disorders, such as autism spectrum disorder (ASD), schizophrenia, and Alzheimer's disease, suggesting its role in neuronal development and function. 2. **Immune-Mediated Diseases:** NEO1 dysregulation may contribute to immune-mediated diseases, including multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. 3. **Cancer:** NEO1 has been implicated in cancer progression, particularly in glioblastoma and other brain tumors, highlighting its potential as a therapeutic target. 4. **Neurodegenerative Diseases:** NEO1 may play a role in neurodegenerative diseases, such as Parkinson's disease and amyotrophic lateral sclerosis (ALS), where its expression and function are altered. In conclusion, NEO1 is a complex and multifunctional protein that plays a critical role in immune regulation, neuronal development, and tissue homeostasis. Further research is necessary to fully elucidate the mechanisms underlying NEO1's functions and to explore its therapeutic potential in various diseases.

Genular Protein ID: 1655154581

Symbol: NEO1_HUMAN

Name: Neogenin

UniProtKB Accession Codes:

Q92859 B7ZKM9 B7ZKN0 O00340 Q17RX1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 23 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9121761

Title: Identification and characterization of neogenin, a DCC-related gene.

PubMed ID: 9121761

DOI: 10.1038/sj.onc.1200935

PubMed ID: 9169140

Title: Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3-q23.

PubMed ID: 9169140

DOI: 10.1006/geno.1997.4688

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17204444

Title: Neogenin: A multi-functional receptor regulating diverse developmental processes.

PubMed ID: 17204444

DOI: 10.1016/j.biocel.2006.11.009

PubMed ID: 18287331

Title: Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin.

PubMed ID: 18287331

DOI: 10.1152/ajpcell.00563.2007

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21149453

Title: Neogenin, a receptor for bone morphogenetic proteins.

PubMed ID: 21149453

DOI: 10.1074/jbc.m110.180919

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1461
  • Mass: 160017
  • Checksum: 4AADF1EEBCAFD82C
  • Sequence:
    • MAAERGARRL LSTPSFWLYC LLLLGRRAPG AAAARSGSAP QSPGASIRTF TPFYFLVEPV 
DTLSVRGSSV ILNCSAYSEP SPKIEWKKDG TFLNLVSDDR RQLLPDGSLF ISNVVHSKHN 
KPDEGYYQCV ATVESLGTII SRTAKLIVAG LPRFTSQPEP SSVYAGNNAI LNCEVNADLV 
PFVRWEQNRQ PLLLDDRVIK LPSGMLVISN ATEGDGGLYR CVVESGGPPK YSDEVELKVL 
PDPEVISDLV FLKQPSPLVR VIGQDVVLPC VASGLPTPTI KWMKNEEALD TESSERLVLL 
AGGSLEISDV TEDDAGTYFC IADNGNETIE AQAELTVQAQ PEFLKQPTNI YAHESMDIVF 
ECEVTGKPTP TVKWVKNGDM VIPSDYFKIV KEHNLQVLGL VKSDEGFYQC IAENDVGNAQ 
AGAQLIILEH APATTGPLPS APRDVVASLV STRFIKLTWR TPASDPHGDN LTYSVFYTKE 
GIARERVENT SHPGEMQVTI QNLMPATVYI FRVMAQNKHG SGESSAPLRV ETQPEVQLPG 
PAPNLRAYAA SPTSITVTWE TPVSGNGEIQ NYKLYYMEKG TDKEQDVDVS SHSYTINGLK 
KYTEYSFRVV AYNKHGPGVS TPDVAVRTLS DVPSAAPQNL SLEVRNSKSI MIHWQPPAPA 
TQNGQITGYK IRYRKASRKS DVTETLVSGT QLSQLIEGLD RGTEYNFRVA ALTINGTGPA 
TDWLSAETFE SDLDETRVPE VPSSLHVRPL VTSIVVSWTP PENQNIVVRG YAIGYGIGSP 
HAQTIKVDYK QRYYTIENLD PSSHYVITLK AFNNVGEGIP LYESAVTRPH TDTSEVDLFV 
INAPYTPVPD PTPMMPPVGV QASILSHDTI RITWADNSLP KHQKITDSRY YTVRWKTNIP 
ANTKYKNANA TTLSYLVTGL KPNTLYEFSV MVTKGRRSST WSMTAHGTTF ELVPTSPPKD 
VTVVSKEGKP KTIIVNWQPP SEANGKITGY IIYYSTDVNA EIHDWVIEPV VGNRLTHQIQ 
ELTLDTPYYF KIQARNSKGM GPMSEAVQFR TPKADSSDKM PNDQASGSGG KGSRLPDLGS 
DYKPPMSGSN SPHGSPTSPL DSNMLLVIIV SVGVITIVVV VIIAVFCTRR TTSHQKKKRA 
ACKSVNGSHK YKGNSKDVKP PDLWIHHERL ELKPIDKSPD PNPIMTDTPI PRNSQDITPV 
DNSMDSNIHQ RRNSYRGHES EDSMSTLAGR RGMRPKMMMP FDSQPPQPVI SAHPIHSLDN 
PHHHFHSSSL ASPARSHLYH PGSPWPIGTS MSLSDRANST ESVRNTPSTD TMPASSSQTC 
CTDHQDPEGA TSSSYLASSQ EEDSGQSLPT AHVRPSHPLK SFAVPAIPPP GPPTYDPALP 
STPLLSQQAL NHHIHSVKTA SIGTLGRSRP PMPVVVPSAP EVQETTRMLE DSESSYEPDE 
LTKEMAHLEG LMKDLNAITT A

Genular Protein ID: 2851259679

Symbol: Q59FP8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FP8 H0YNI3

Database IDs:

ARBA 4 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 PharmGKB 1 Proteomes 2 ProteomicsDB 2 RefSeq 3 SAM 2 SMART 3 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1130
  • Mass: 123959
  • Checksum: 0FAF047DEC73E59C
  • Sequence:
    • GNETIEAQAE LTVQAQPEFL KQPTNIYAHE SMDIVFECEV TGKPTPTVKW VKNGDMVIPS 
DYFKIVKEHN LQVLGLVKSD EGFYQCIAEN DVGNAQAGAQ LIILEHDVAI PTLPPTSLTS 
ATTDHLAPAT TGPLPSAPRD VVASLVSTRF IKLTWRTPAS DPHGDNLTYS VFYTKEGIAR 
ERVENTSHPG EMQVTIQNLM PATVYIFRVM AQNKHGSGES SAPLRVETQP EVQLPGPAPN 
LRAYAASPTS ITVTWETPVS GNGEIQNYKL YYMEKGTDKE QDVDVSSHSY TINGLKKYTE 
YSFRVVAYNK HGPGVSTPDV AVRTLSDVPS AAPQNLSLEV RNSKSIMIHW QPPAPATQNG 
QITGYKIRYR KASRKSDVTE TLVSGTQLSQ LIEGLDRGTE YNFRVAALTI NGTGPATDWL 
SAETFESDLD ETRVPEVPSS LHVRPLVTSI VVSWTPPENQ NIVVRGYAIG YGIGSPHAQT 
IKVDYKQRYY TIENLDPSSH YVITLKAFNN VGEGIPLYES AVTRPHTVPD PTPMMPPVGV 
QASILSHDTI RITWADNSLP KHQKITDSRY YTVRWKTNIP ANTKYKNANA TTLSYLVTGL 
KPNTLYEFSV MVTKGRRSST WSMTAHGTTF ELVPTSPPKD VTVVSKEGKP KTIIVNWQPP 
SEANGKITGY IIYYSTDVNA EIHDWVIEPV VGNRLTHQIQ ELTLDTPYYF KIQARNSKGM 
GPMSEAVQFR TPKASGSGGK GSRLPDLGSD YKPPMSGSNS PHGSPTSPLD SNMLLVIIVS 
VGVITIVVVV IIAVFCTRRT TSHQKKKRAA CKSVNGSHKY KGNSKDVKPP DLWIHHERLE 
LKPIDKSPDP NPIMTDTPIP RNSQDITPVD NSMDSNIHQR RNSYRGHESE DSMSTLAGRR 
GMRPKMMMPF DSQPPQPVIS AHPIHSLDNP HHHFHSSSLA SPARSHLYHP GSPWPIGTSM 
SLSDRANSTE SVRNTPSTDT MPASSSQTCC TDHQDPEGAT SSSYLASSQE EDSGQSLPTA 
HVRPSHPLKS FAVPAIPPPG PPTYDPALPS TPLLSQQALN HHIHSVKTAS IGTLGRSRPP 
MPVVVPSAPE VQETTRMLED SESSYEPDEL TKEMAHLEGL MKDLNAITTA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.