Details for: GPM6A
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 822.0760
Cell Significance Index: -127.8700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 501.3732
Cell Significance Index: -127.1700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 103.7345
Cell Significance Index: -127.9000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 42.5592
Cell Significance Index: -114.0100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 32.5059
Cell Significance Index: -128.2700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 15.6082
Cell Significance Index: -34.1600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 13.8008
Cell Significance Index: 774.4300 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 11.4364
Cell Significance Index: 159.9200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 8.6893
Cell Significance Index: 148.9100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 6.9409
Cell Significance Index: 166.4600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 6.6877
Cell Significance Index: 411.0600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 5.3101
Cell Significance Index: 357.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 4.5938
Cell Significance Index: 1647.7100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 4.2740
Cell Significance Index: 8047.5200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.6084
Cell Significance Index: 723.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.5277
Cell Significance Index: 185.2200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.8749
Cell Significance Index: 82.0400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.7593
Cell Significance Index: 1908.4400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.0623
Cell Significance Index: 91.2200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.7576
Cell Significance Index: 66.5600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.5131
Cell Significance Index: 960.9500 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.8498
Cell Significance Index: 6.5500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.6351
Cell Significance Index: 13.5800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.4799
Cell Significance Index: 49.9700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2548
Cell Significance Index: 392.1900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0054
Cell Significance Index: 9.8700 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.0037
Cell Significance Index: 0.0400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0081
Cell Significance Index: -1.1800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0864
Cell Significance Index: -117.5200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.1010
Cell Significance Index: -74.8400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1375
Cell Significance Index: -77.5600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.1426
Cell Significance Index: -104.5500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1475
Cell Significance Index: -66.9600 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1818
Cell Significance Index: -113.5000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1843
Cell Significance Index: -139.4800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.2298
Cell Significance Index: -125.5000 - Cell Name: mature astrocyte (CL0002627)
Fold Change: -0.2592
Cell Significance Index: -2.8800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2645
Cell Significance Index: -5.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.3491
Cell Significance Index: -100.4400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.3944
Cell Significance Index: -71.1000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.5402
Cell Significance Index: -113.7700 - Cell Name: Mueller cell (CL0000636)
Fold Change: -0.5706
Cell Significance Index: -4.3900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.5950
Cell Significance Index: -118.0700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.6047
Cell Significance Index: -115.0900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.6253
Cell Significance Index: -101.7000 - Cell Name: neural progenitor cell (CL0011020)
Fold Change: -0.6519
Cell Significance Index: -6.4500 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.7079
Cell Significance Index: -12.2400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.7404
Cell Significance Index: -126.4400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.7501
Cell Significance Index: -92.2300 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.8283
Cell Significance Index: -9.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.8718
Cell Significance Index: -112.6300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.8935
Cell Significance Index: -122.7000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.9517
Cell Significance Index: -44.3800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.9789
Cell Significance Index: -115.4500 - Cell Name: neural cell (CL0002319)
Fold Change: -0.9815
Cell Significance Index: -11.4500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.9862
Cell Significance Index: -100.7500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.9927
Cell Significance Index: -32.5000 - Cell Name: odontoblast (CL0000060)
Fold Change: -1.0011
Cell Significance Index: -128.3400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -1.0335
Cell Significance Index: -120.4500 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -1.0375
Cell Significance Index: -13.8400 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -1.0412
Cell Significance Index: -7.5700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.1379
Cell Significance Index: -31.8000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.2079
Cell Significance Index: -38.4700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -1.2308
Cell Significance Index: -26.9500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -1.2477
Cell Significance Index: -142.4300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -1.2512
Cell Significance Index: -143.3400 - Cell Name: glioblast (CL0000030)
Fold Change: -1.2565
Cell Significance Index: -7.8900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -1.3235
Cell Significance Index: -104.8200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -1.3425
Cell Significance Index: -60.8500 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -1.4183
Cell Significance Index: -13.5000 - Cell Name: neuron (CL0000540)
Fold Change: -1.4796
Cell Significance Index: -14.0300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -1.5073
Cell Significance Index: -112.3400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.5280
Cell Significance Index: -32.4300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.5405
Cell Significance Index: -97.0900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -1.5794
Cell Significance Index: -109.2300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.6718
Cell Significance Index: -87.0800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.7115
Cell Significance Index: -131.3400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.7150
Cell Significance Index: -34.4300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -1.8100
Cell Significance Index: -116.7700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -1.8101
Cell Significance Index: -108.6700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -1.8246
Cell Significance Index: -26.1300 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -1.9356
Cell Significance Index: -24.4300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.9397
Cell Significance Index: -100.7600 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -1.9519
Cell Significance Index: -24.3400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -2.0057
Cell Significance Index: -24.8800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -2.0300
Cell Significance Index: -124.4600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -2.1378
Cell Significance Index: -74.8900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -2.3177
Cell Significance Index: -108.9300 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -2.3218
Cell Significance Index: -30.1100 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -2.3693
Cell Significance Index: -59.1000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -2.5760
Cell Significance Index: -55.6600 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -2.7184
Cell Significance Index: -17.6900 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -2.7804
Cell Significance Index: -58.0300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -3.0423
Cell Significance Index: -105.7200 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -3.1090
Cell Significance Index: -114.1300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -3.2705
Cell Significance Index: -104.7500 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -3.3304
Cell Significance Index: -34.2400 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -3.4253
Cell Significance Index: -41.5200 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -3.5356
Cell Significance Index: -50.3300 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -3.5416
Cell Significance Index: -44.7000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2950729633
Symbol: GPM6A_HUMAN
Name: Neuronal membrane glycoprotein M6-a
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8893821
Title: Isolation and mapping of the human glycoprotein M6 gene (GPM6A) to 4q33-->q34.
PubMed ID: 8893821
DOI: 10.1159/000134401
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8661015
PubMed ID: 19298174
Title: Human GPM6A is associated with differentiation and neuronal migration of neurons derived from human embryonic stem cells.
PubMed ID: 19298174
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
PubMed ID: 24705354
Title: The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease.
PubMed ID: 24705354
DOI: 10.1093/hmg/ddu137
Sequence Information:
- Length: 278
- Mass: 31210
- Checksum: DD0DB598C0E86B5D
- Sequence:
MEENMEEGQT QKGCFECCIK CLGGIPYASL IATILLYAGV ALFCGCGHEA LSGTVNILQT YFEMARTAGD TLDVFTMIDI FKYVIYGIAA AFFVYGILLM VEGFFTTGAI KDLYGDFKIT TCGRCVSAWF IMLTYLFMLA WLGVTAFTSL PVYMYFNLWT ICRNTTLVEG ANLCLDLRQF GIVTIGEEKK ICTVSENFLR MCESTELNMT FHLFIVALAG AGAAVIAMVH YLMVLSANWA YVKDACRMQK YEDIKSKEEQ ELHDIHSTRS KERLNAYT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.