Details for: MAGI2

Gene ID: 9863

Symbol: MAGI2

Ensembl ID: ENSG00000187391

Description: membrane associated guanylate kinase, WW and PDZ domain containing 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 948.9202
    Cell Significance Index: -147.6000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 583.2598
    Cell Significance Index: -147.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 309.1358
    Cell Significance Index: -145.9500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 284.0319
    Cell Significance Index: -115.3900
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 121.2054
    Cell Significance Index: -115.7200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 119.7367
    Cell Significance Index: -147.6300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 40.6244
    Cell Significance Index: -88.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 37.5388
    Cell Significance Index: -148.1300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 8.2639
    Cell Significance Index: 198.1900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 7.4804
    Cell Significance Index: 459.7800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 7.2918
    Cell Significance Index: 101.9700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 6.4539
    Cell Significance Index: 2314.9100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.6520
    Cell Significance Index: 380.0400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.7409
    Cell Significance Index: 135.2900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 4.3678
    Cell Significance Index: 245.1000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 4.3208
    Cell Significance Index: 2988.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.8357
    Cell Significance Index: 769.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 3.8105
    Cell Significance Index: 292.4200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.6788
    Cell Significance Index: 162.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 3.6714
    Cell Significance Index: 4992.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.5962
    Cell Significance Index: 6771.2200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.4106
    Cell Significance Index: 129.1500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.0935
    Cell Significance Index: 1964.6700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.8959
    Cell Significance Index: 56.5200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.8782
    Cell Significance Index: 2891.4700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.8212
    Cell Significance Index: 31.2100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.7476
    Cell Significance Index: 37.3600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.6438
    Cell Significance Index: 100.7800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.5735
    Cell Significance Index: 714.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.3714
    Cell Significance Index: 2529.1900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2516
    Cell Significance Index: 238.2000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.9878
    Cell Significance Index: 10.2900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.7311
    Cell Significance Index: 19.5900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6632
    Cell Significance Index: 131.6200
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.5942
    Cell Significance Index: 9.0400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.4241
    Cell Significance Index: 5.5000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3882
    Cell Significance Index: 350.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.2717
    Cell Significance Index: 28.2900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2494
    Cell Significance Index: 44.9500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0896
    Cell Significance Index: -55.9700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0945
    Cell Significance Index: -69.9800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1395
    Cell Significance Index: -1.7400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.1485
    Cell Significance Index: -108.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1750
    Cell Significance Index: -98.6700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.2146
    Cell Significance Index: -162.4600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.2219
    Cell Significance Index: -121.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.2336
    Cell Significance Index: -37.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2708
    Cell Significance Index: -39.3700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.2990
    Cell Significance Index: -132.2000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3057
    Cell Significance Index: -3.3300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.3264
    Cell Significance Index: -32.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3780
    Cell Significance Index: -46.4800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4130
    Cell Significance Index: -118.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.4890
    Cell Significance Index: -102.9900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5179
    Cell Significance Index: -10.2400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.5863
    Cell Significance Index: -36.9500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.6050
    Cell Significance Index: -83.0900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.6647
    Cell Significance Index: -30.1300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.7076
    Cell Significance Index: -76.9700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.7418
    Cell Significance Index: -126.6600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.7923
    Cell Significance Index: -10.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.8066
    Cell Significance Index: -23.2400
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.9616
    Cell Significance Index: -10.3100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -1.0216
    Cell Significance Index: -14.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -1.0693
    Cell Significance Index: -138.1400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.1108
    Cell Significance Index: -129.4500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -1.1110
    Cell Significance Index: -39.0400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.1189
    Cell Significance Index: -24.5000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.2236
    Cell Significance Index: -124.9900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.2368
    Cell Significance Index: -145.8600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.2882
    Cell Significance Index: -27.3400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.3039
    Cell Significance Index: -19.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.3432
    Cell Significance Index: -19.2400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.3509
    Cell Significance Index: -154.7700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -1.3678
    Cell Significance Index: -175.3400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -1.3786
    Cell Significance Index: -157.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.3795
    Cell Significance Index: -95.4000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -1.4602
    Cell Significance Index: -46.7700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.4761
    Cell Significance Index: -76.6800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.5890
    Cell Significance Index: -125.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.6013
    Cell Significance Index: -96.1400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.7034
    Cell Significance Index: -55.7700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -1.7264
    Cell Significance Index: -23.0300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.7571
    Cell Significance Index: -55.9600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.7814
    Cell Significance Index: -44.5300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.8429
    Cell Significance Index: -137.3500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.8569
    Cell Significance Index: -37.2800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -1.8739
    Cell Significance Index: -32.4000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.9010
    Cell Significance Index: -99.8100
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.9638
    Cell Significance Index: -22.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.9856
    Cell Significance Index: -41.1900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -2.0092
    Cell Significance Index: -25.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -2.1688
    Cell Significance Index: -139.9200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.2029
    Cell Significance Index: -114.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -2.2173
    Cell Significance Index: -156.8200
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -2.4465
    Cell Significance Index: -28.0000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -2.4598
    Cell Significance Index: -31.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.5373
    Cell Significance Index: -119.2500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.6199
    Cell Significance Index: -91.7800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -2.6878
    Cell Significance Index: -58.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MAGI2 is a large protein (approximately 120 kDa) consisting of three distinct domains: a WW domain, a PDZ domain, and a guanylate kinase domain. The WW domain is involved in protein-protein interactions, while the PDZ domain is crucial for binding to specific motifs in target proteins. The guanylate kinase domain is responsible for catalyzing the transfer of a guanosine triphosphate (GTP) moiety to a protein substrate. These domains work together to regulate various cellular processes, including cell adhesion, migration, and signaling. **Pathways and Functions:** MAGI2 is involved in numerous signaling pathways, including: 1. **Cell-cell communication:** MAGI2 interacts with other proteins to regulate cell-cell adhesion and communication, particularly in the context of tight junctions and adherens junctions. 2. **Signaling receptor complex adaptor activity:** MAGI2 acts as a scaffold protein to organize signaling receptors and adaptors, facilitating the transmission of signals from the cell surface to the cytoplasm. 3. **Regulation of cell migration:** MAGI2 inhibits cell migration by regulating the activity of proteins involved in the Rho GTPase pathway. 4. **Negative regulation of cell population proliferation:** MAGI2 suppresses cell proliferation by interacting with proteins involved in the PI3K/Akt signaling pathway. 5. **Regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction:** MAGI2 inhibits this pathway, which is involved in cell survival and metabolism. **Clinical Significance:** MAGI2's involvement in various cellular processes and signaling pathways makes it an important protein for understanding the pathogenesis of several diseases. For example: 1. **Neurological disorders:** MAGI2's role in neuronal development and function suggests that alterations in MAGI2 expression or function may contribute to neurological disorders, such as autism, schizophrenia, and Alzheimer's disease. 2. **Cancer:** MAGI2's involvement in cell migration and proliferation suggests that it may play a role in cancer development and progression. 3. **Immune system disorders:** MAGI2's expression in immune cells and its involvement in immune-related signaling pathways suggest that it may be involved in immune system disorders, such as autoimmune diseases. In conclusion, MAGI2 is a complex protein that plays a crucial role in various cellular processes, including cell-cell communication, signaling, and regulation of cell migration and proliferation. Its widespread expression in different cell types and tissues highlights its importance in maintaining tissue homeostasis and regulating cellular responses to external stimuli. Further research is needed to fully understand the mechanisms by which MAGI2 regulates cellular processes and to explore its potential role in various diseases.

Genular Protein ID: 2401122005

Symbol: MAGI2_HUMAN

Name: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

UniProtKB Accession Codes:

Q86UL8 A4D1C1 A7E2C3 O60434 O60510 Q86UI7 Q9NP44 Q9UDQ5 Q9UDU1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 38 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PROSITE 5 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9647693

Title: Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins.

PubMed ID: 9647693

DOI: 10.1006/mcne.1998.0677

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10760291

Title: Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2.

PubMed ID: 10760291

DOI: 10.1073/pnas.97.8.4233

PubMed ID: 11707428

Title: Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex.

PubMed ID: 11707428

DOI: 10.1074/jbc.c100556200

PubMed ID: 16464232

Title: Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring.

PubMed ID: 16464232

DOI: 10.1111/j.1471-4159.2006.03679.x

PubMed ID: 23751499

Title: The adhesion protein IgSF9b is coupled to neuroligin 2 via S-SCAM to promote inhibitory synapse development.

PubMed ID: 23751499

DOI: 10.1083/jcb.201209132

PubMed ID: 24608321

Title: Phosphorylation of the Usher syndrome 1G protein SANS controls Magi2-mediated endocytosis.

PubMed ID: 24608321

DOI: 10.1093/hmg/ddu104

PubMed ID: 27932480

Title: MAGI2 mutations cause congenital nephrotic syndrome.

PubMed ID: 27932480

DOI: 10.1681/asn.2016040387

Sequence Information:

  • Length: 1455
  • Mass: 158754
  • Checksum: 93E170D070A70A9C
  • Sequence:
    • MSKSLKKKSH WTSKVHESVI GRNPEGQLGF ELKGGAENGQ FPYLGEVKPG KVAYESGSKL 
VSEELLLEVN ETPVAGLTIR DVLAVIKHCK DPLRLKCVKQ GGIVDKDLRH YLNLRFQKGS 
VDHELQQIIR DNLYLRTVPC TTRPHKEGEV PGVDYIFITV EDFMELEKSG ALLESGTYED 
NYYGTPKPPA EPAPLLLNVT DQILPGATPS AEGKRKRNKS VSNMEKASIE PPEEEEEERP 
VVNGNGVVVT PESSEHEDKS AGASGEMPSQ PYPAPVYSQP EELKEQMDDT KPTKPEDNEE 
PDPLPDNWEM AYTEKGEVYF IDHNTKTTSW LDPRLAKKAK PPEECKENEL PYGWEKIDDP 
IYGTYYVDHI NRRTQFENPV LEAKRKLQQH NMPHTELGTK PLQAPGFREK PLFTRDASQL 
KGTFLSTTLK KSNMGFGFTI IGGDEPDEFL QVKSVIPDGP AAQDGKMETG DVIVYINEVC 
VLGHTHADVV KLFQSVPIGQ SVNLVLCRGY PLPFDPEDPA NSMVPPLAIM ERPPPVMVNG 
RHNYETYLEY ISRTSQSVPD ITDRPPHSLH SMPTDGQLDG TYPPPVHDDN VSMASSGATQ 
AELMTLTIVK GAQGFGFTIA DSPTGQRVKQ ILDIQGCPGL CEGDLIVEIN QQNVQNLSHT 
EVVDILKDCP IGSETSLIIH RGGFFSPWKT PKPIMDRWEN QGSPQTSLSA PAIPQNLPFP 
PALHRSSFPD STEAFDPRKP DPYELYEKSR AIYESRQQVP PRTSFRMDSS GPDYKELDVH 
LRRMESGFGF RILGGDEPGQ PILIGAVIAM GSADRDGRLH PGDELVYVDG IPVAGKTHRY 
VIDLMHHAAR NGQVNLTVRR KVLCGGEPCP ENGRSPGSVS THHSSPRSDY ATYTNSNHAA 
PSSNASPPEG FASHSLQTSD VVIHRKENEG FGFVIISSLN RPESGSTITV PHKIGRIIDG 
SPADRCAKLK VGDRILAVNG QSIINMPHAD IVKLIKDAGL SVTLRIIPQE ELNSPTSAPS 
SEKQSPMAQQ SPLAQQSPLA QPSPATPNSP IAQPAPPQPL QLQGHENSYR SEVKARQDVK 
PDIRQPPFTD YRQPPLDYRQ PPGGDYQQPP PLDYRQPPLL DYRQHSPDTR QYPLSDYRQP 
QDFDYFTVDM EKGAKGFGFS IRGGREYKMD LYVLRLAEDG PAIRNGRMRV GDQIIEINGE 
STRDMTHARA IELIKSGGRR VRLLLKRGTG QVPEYDEPAP WSSPAAAAPG LPEVGVSLDD 
GLAPFSPSHP APPSDPSHQI SPGPTWDIKR EHDVRKPKEL SACGQKKQRL GEQRERSASP 
QRAARPRLEE APGGQGRPEA GRPASEARAP GLAAADAADA ARAGGKEAPR AAAGSELCRR 
EGPGAAPAFA GPGGGGSGAL EAEGRAGARA GPRPGPRPPG GAPARKAAVA PGPWKVPGSD 
KLPSVLKPGA SAASR

Genular Protein ID: 3026157830

Symbol: B7Z4H4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z4H4

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 11 Gene3D 3 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 8 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Sequence Information:

  • Length: 1253
  • Mass: 138877
  • Checksum: 9DB5F5EF602919C5
  • Sequence:
    • MSKSLKKKSH WTSKVHESVI GRNPEGQLGF ELKGGAENGQ FPYLGEVKPG KVAYESGSKL 
VSEELLLEVN ETPVAGLTIR DVLAVIKHCK DPLRLKCVKQ GGIVDKDLRH YLNLRFQKGS 
VDHELQQIIR DNLYLRTVPC TTRPHKEGEV PGVDYIFITV EDFMELEKSG ALLESGTYED 
NYYGTPKPPA EPAPLLLNVT DQILPGATPS AEGKRKRNKS VSNMEKASIE PPEEEEEERP 
VVNGNGVVVT PESSEHEDKS AGASGEMPSQ PYPAPVYSQP EELKEQMDDT KPTKPEDNEE 
PDPLPDNWEM AYTEKGEVYF IDHNTKTTSW LDPRLAKKAK PPEECKENEL PYGWEKIDDP 
IYGTYYVDHI NRRTQFENPV LEAKRKLQQH NMPHTELGTK PLQAPGFREK PLFTRDASQL 
KGTFLSTTLK KSNMGFGFTI IGGDEPDEFL QVKSVIPDGP AAQDGKMETG DVIVYINEVC 
VLGHTHADVV KLFQSVPIGQ SVNLVLCRGY PLPFDPEDPA NSMVPPLAIM ERPPPVMVNG 
RHNYETYLEY ISRTSQSVPD ITDRPPHSLH SMPTDGQLDG TYPPPVHDDN VSMASSGATQ 
AELMTLTIVK GAQGFGFTIA DSPTGQRVKQ ILDIQGCPGL CEGDLIVEIN QQNVQNLSHT 
EVVDILKDCP IGSETSLIIH RGGFFSPWKT PKPIMDRWEN QGSPQTSLSA PAIPQNLPFP 
PALHRSSFPD STEAFDPRKP DPYELYEKSR AIYESRQQVP PRTSFRMDSS GPDYKELDVH 
LRRMESGFGF RILGGDEPGQ PILIGAVIAM GSADRDGRLH PGDELVYVDG IPVAGKTHRY 
VIDLMHHAAR NGQVNLTVRR KVLCGGEPCP ENGRSPGSVS THHSSPRSDY ATYTNSNHAA 
PSSNASPPEG FASHSLQTSD VVIHRKENEG FGFVIISSLN RPESGSTITV PHKIGRIIDG 
SPADRCAKLK VGDRILAVNG QSIINMPHAD IVKLIKDAGL SVTLRIIPQE ELNSPTSAPS 
SEKQSPMAQQ SPLAQQSPLA QPSPATPNSP IAQPAPPQPL QLQGHENSYR SEVKARQDVK 
PDIRQPPFTD YRQPPLDYRQ PPGGDYQQPP PLDYRQPPLL DYRQHSPDTR QYPLSDYRQP 
QDFDYFTVDM EKGAKGFGFS IRGGREYKMD LYVLRLAEDG PAIRNGRMRV GDQIIEINGE 
STRDMTHARA IELIKSGGRR VRLLLKRGTG QVPEYDEPAP AQAVLLRFRL TAF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.