Details for: SSBP2
Gene ID: 23635
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SSBP2
Ensembl ID: ENSG00000145687
Description: single stranded DNA binding protein 2
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 61.83rCSI 84.61%PRS 54.32
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CSI 54.01rCSI 64.51%PRS 42.29
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CSI 52.85rCSI 65.75%PRS 40.56
-
CSI 51.94rCSI 83.54%PRS 44.52
-
CSI 48.96rCSI 99.35%PRS 40.13
-
CSI 48.39rCSI 62.38%PRS 43.72
-
CSI 47.79rCSI 80.21%PRS 42.47
-
CSI 45.86rCSI 75.09%PRS 49.93
-
CSI 43.81rCSI 77.37%PRS 41.56
-
CSI 37.95rCSI 86.1%PRS 64.76
-
CSI 33.32rCSI 62.4%PRS 49
-
CSI 33.21rCSI 23.84%PRS 75.14
-
CSI 31.36rCSI 46.11%PRS 54.34
-
CSI 30.87rCSI 75.02%PRS 41.07
-
CSI 29.09rCSI 50.99%PRS 52.59
-
CSI 27.18rCSI 70.8%PRS 58.24
-
CSI 26.41rCSI 19.77%PRS 75.94
-
CSI 26.23rCSI 81.96%PRS 44.1
-
CSI 25.68rCSI 80.31%PRS 46.62
-
CSI 25.57rCSI 54.48%PRS 32
-
CSI 25.4rCSI 32.62%PRS 53.49
-
CSI 25.39rCSI 67.62%PRS 49.94
-
CSI 25.38rCSI 23.99%PRS 60.16
-
CSI 25.25rCSI 63.27%PRS 84.5
-
CSI 24.99rCSI 39.86%PRS 53.34
-
CSI 24.57rCSI 17.25%PRS 78.9
-
CSI 23.98rCSI 19.85%PRS 62.76
-
CSI 23.8rCSI 27.49%PRS 53.89
-
CSI 23.59rCSI 18.89%PRS 81.14
-
CSI 23.14rCSI 15.38%PRS 63.75
-
CSI 23.09rCSI 32.07%PRS 59.37
-
CSI 22.37rCSI 48.52%PRS 48.64
-
CSI 22.05rCSI 60.78%PRS 56.41
-
CSI 21.99rCSI 18.86%PRS 68.8
-
CSI 21.97rCSI 49.26%PRS 43.25
-
CSI 21.86rCSI 16.24%PRS 74.1
-
CSI 21.85rCSI 78.61%PRS 40.9
-
CSI 21.42rCSI 16.93%PRS 47.53
-
CSI 21.41rCSI 73.33%PRS 49.64
-
CSI 21.02rCSI 16.99%PRS 71.17
-
CSI 20.18rCSI 76.26%PRS 43.28
-
CSI 19.51rCSI 43.1%PRS 46.87
-
CSI 19.46rCSI 20.33%PRS 82.88
-
CSI 19.18rCSI 19.74%PRS 77.23
-
CSI 19rCSI 45.67%PRS 68.45
-
CSI 18.85rCSI 32.6%PRS 50.74
-
CSI 17.9rCSI 51.1%PRS 72.5
-
CSI 17.81rCSI 83.79%PRS 55.53
-
CSI 17.52rCSI 45.04%PRS 60.5
-
CSI 17.42rCSI 59.02%PRS 53.86
-
CSI 17.27rCSI 14.89%PRS 66.3
-
CSI 17.2rCSI 15.07%PRS 70.47
-
CSI 17.17rCSI 56.9%PRS 64.76
-
CSI 17.07rCSI 15.78%PRS 80.24
-
CSI 17rCSI 14.95%PRS 48.47
-
CSI 16.66rCSI 48.28%PRS 50.29
-
CSI 16.54rCSI 21.22%PRS 57.87
-
CSI 16.44rCSI 39.33%PRS 47.95
-
CSI 16.38rCSI 23.51%PRS 50.51
-
CSI 15.99rCSI 32.11%PRS 49.74
-
CSI 15.97rCSI 22.12%PRS 61.83
-
CSI 15.8rCSI 29.83%PRS 71.25
-
CSI 15.46rCSI 61.25%PRS 60.15
-
CSI 15.33rCSI 80.6%PRS 55.13
-
CSI 15.15rCSI 12.7%PRS 65.07
-
CSI 15.05rCSI 34.35%PRS 52.45
-
CSI 14.9rCSI 65.47%PRS 57.44
-
CSI 14.86rCSI 38.74%PRS 60.48
-
CSI 14.61rCSI 19.98%PRS 66.69
-
CSI 14.58rCSI 72.51%PRS 58.3
-
CSI 14.52rCSI 22.17%PRS 61.24
-
CSI 14.5rCSI 12.74%PRS 66.19
-
CSI 14.28rCSI 53.88%PRS 47.4
-
CSI 14.22rCSI 17.31%PRS 68.15
-
CSI 14.11rCSI 11.7%PRS 59.73
-
CSI 14.03rCSI 46.11%PRS 47.62
-
CSI 13.99rCSI 22.51%PRS 50.27
-
CSI 13.74rCSI 12.68%PRS 62.16
-
CSI 13.5rCSI 10.21%PRS 74.58
-
CSI 13.46rCSI 14.43%PRS 59.98
-
CSI 13.41rCSI 55.25%PRS 71.82
-
CSI 13.28rCSI 43.08%PRS 61.32
-
CSI 13.2rCSI 30.48%PRS 49.76
-
CSI 13.17rCSI 77.77%PRS 55.54
-
CSI 13.14rCSI 18.63%PRS 56.87
-
CSI 13.08rCSI 54.28%PRS 64.37
-
CSI 13.05rCSI 62.53%PRS 60.7
-
CSI 12.93rCSI 76.11%PRS 43.73
-
CSI 12.9rCSI 28.4%PRS 65
-
CSI 12.78rCSI 8.9%PRS 75.95
-
CSI 12.7rCSI 86.43%PRS 56.45
-
CSI 12.48rCSI 89.23%PRS 53.81
-
CSI 12.47rCSI 82.79%PRS 57.88
-
CSI 12.37rCSI 22.23%PRS 53.69
-
CSI 12.16rCSI 9.57%PRS 67.38
-
CSI 12.16rCSI 14.25%PRS 77.16
-
CSI 11.81rCSI 23.45%PRS 58.44
-
CSI 11.76rCSI 16.03%PRS 52.43
-
CSI 11.48rCSI 8.63%PRS 66.2
-
CSI 11.47rCSI 18.58%PRS 57.34
-
CSI 0.2rCSI 2.8%PRS 75.6%
-
CSI 0.4rCSI 2.0%PRS 69.9%
-
CSI 0.5rCSI 2.1%PRS 73.6%
-
CSI 0.5rCSI 2.9%PRS 88.3%
-
CSI 0.6rCSI 3.2%PRS 70.3%
-
CSI 0.6rCSI 3.2%PRS 69.9%
-
CSI 0.6rCSI 6.9%PRS 86.2%
-
CSI 0.7rCSI 3.8%PRS 82.2%
-
CSI 0.8rCSI 1.0%PRS 67.2%
-
CSI 0.9rCSI 5.6%PRS 87.7%
-
CSI 0.9rCSI 1.8%PRS 63.6%
-
CSI 1.2rCSI 15.0%PRS 73.5%
-
CSI 1.3rCSI 4.3%PRS 83.0%
-
CSI 1.3rCSI 3.0%PRS 64.4%
-
CSI 1.4rCSI 6.5%PRS 77.4%
-
CSI 1.4rCSI 1.9%PRS 65.5%
-
CSI 1.5rCSI 16.1%PRS 82.0%
-
CSI 1.6rCSI 2.4%PRS 58.8%
-
CSI 1.6rCSI 7.2%PRS 87.8%
-
CSI 1.6rCSI 7.1%PRS 51.2%
-
CSI 1.7rCSI 3.1%PRS 76.0%
-
CSI 1.7rCSI 1.7%PRS 63.3%
-
CSI 1.8rCSI 4.0%PRS 58.6%
-
CSI 1.8rCSI 19.1%PRS 59.1%
-
CSI 1.9rCSI 13.2%PRS 75.2%
-
CSI 2.0rCSI 2.9%PRS 72.3%
-
CSI 2.0rCSI 2.1%PRS 64.3%
-
CSI 2.1rCSI 4.1%PRS 79.3%
-
CSI 2.2rCSI 5.8%PRS 72.2%
-
CSI 2.2rCSI 2.0%PRS 57.4%
-
CSI 2.3rCSI 7.8%PRS 83.3%
-
CSI 2.3rCSI 4.1%PRS 52.7%
-
CSI 2.3rCSI 1.5%PRS 73.8%
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CSI 2.3rCSI 9.0%PRS 80.8%
-
CSI 2.5rCSI 10.4%PRS 74.1%
-
CSI 2.6rCSI 16.5%PRS 42.9%
-
CSI 2.6rCSI 14.7%PRS 71.2%
-
CSI 2.7rCSI 7.9%PRS 83.4%
-
CSI 2.7rCSI 7.6%PRS 57.4%
-
CSI 2.7rCSI 4.0%PRS 62.3%
-
CSI 2.7rCSI 4.0%PRS 76.7%
-
CSI 2.8rCSI 17.7%PRS 70.7%
-
CSI 2.8rCSI 11.0%PRS 63.4%
-
CSI 2.9rCSI 8.7%PRS 78.3%
-
CSI 2.9rCSI 4.6%PRS 71.8%
-
CSI 2.9rCSI 8.0%PRS 73.5%
-
CSI 2.9rCSI 18.2%PRS 52.6%
-
CSI 3.0rCSI 6.3%PRS 78.5%
-
CSI 3.0rCSI 4.0%PRS 74.4%
-
CSI 3.0rCSI 7.9%PRS 76.6%
-
CSI 3.1rCSI 5.1%PRS 66.0%
-
CSI 3.1rCSI 4.9%PRS 62.9%
-
CSI 3.1rCSI 3.3%PRS 66.2%
-
CSI 3.2rCSI 76.1%PRS 42.5%
-
CSI 3.2rCSI 76.3%PRS 41.6%
-
CSI 3.2rCSI 12.5%PRS 37.4%
-
CSI 3.3rCSI 3.2%PRS 51.2%
-
CSI 3.4rCSI 26.3%PRS 72.5%
-
CSI 3.4rCSI 15.2%PRS 78.1%
-
CSI 3.4rCSI 37.6%PRS 73.4%
-
CSI 3.4rCSI 70.1%PRS 51.7%
-
CSI 3.5rCSI 70.3%PRS 52.9%
-
CSI 3.6rCSI 8.1%PRS 57.1%
-
CSI 3.7rCSI 8.9%PRS 78.5%
-
CSI 3.8rCSI 42.2%PRS 79.3%
-
CSI 3.8rCSI 4.5%PRS 69.5%
-
CSI 3.8rCSI 9.0%PRS 69.3%
-
CSI 3.9rCSI 18.7%PRS 59.5%
-
CSI 4.0rCSI 34.8%PRS 58.2%
-
CSI 4.1rCSI 13.0%PRS 65.9%
-
CSI 4.1rCSI 64.9%PRS 65.6%
-
CSI 4.2rCSI 5.7%PRS 67.7%
-
CSI 4.3rCSI 37.4%PRS 47.5%
-
CSI 4.3rCSI 9.3%PRS 68.9%
-
CSI 4.3rCSI 3.7%PRS 71.5%
-
CSI 4.3rCSI 30.6%PRS 52.7%
-
CSI 4.3rCSI 9.0%PRS 62.7%
-
CSI 4.4rCSI 21.8%PRS 89.0%
-
CSI 4.4rCSI 19.0%PRS 73.3%
-
CSI 4.4rCSI 19.6%PRS 44.7%
-
CSI 4.4rCSI 6.6%PRS 66.0%
-
CSI 4.5rCSI 46.2%PRS 54.1%
-
CSI 4.5rCSI 13.0%PRS 80.4%
-
CSI 4.5rCSI 3.5%PRS 78.6%
-
CSI 4.6rCSI 5.7%PRS 62.5%
-
CSI 4.6rCSI 9.8%PRS 60.2%
-
CSI 4.6rCSI 29.7%PRS 78.5%
-
CSI 4.6rCSI 13.4%PRS 62.2%
-
CSI 4.7rCSI 8.4%PRS 59.8%
-
CSI 4.7rCSI 20.8%PRS 60.1%
-
CSI 4.7rCSI 14.6%PRS 69.6%
-
CSI 4.8rCSI 18.3%PRS 51.6%
-
CSI 4.9rCSI 27.5%PRS 45.7%
-
CSI 4.9rCSI 3.6%PRS 77.5%
-
CSI 4.9rCSI 24.0%PRS 71.8%
-
CSI 4.9rCSI 12.9%PRS 79.3%
-
CSI 4.9rCSI 40.2%PRS 53.9%
-
CSI 5.0rCSI 11.1%PRS 68.5%
-
CSI 5.0rCSI 28.8%PRS 59.4%
-
CSI 5.0rCSI 8.8%PRS 69.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3998251845
Symbol: SSBP2_HUMAN
Name: Single-stranded DNA-binding protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12079286
Title: A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.
PubMed ID: 12079286
PubMed ID: 10931946
Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
PubMed ID: 10931946
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 361
- Mass: 37828
- Checksum: EC6F9B08EBFF673A
- Sequence:
MYGKGKSNSS AVPSDSQARE KLALYVYEYL LHVGAQKSAQ TFLSEIRWEK NITLGEPPGF LHSWWCVFWD LYCAAPERRE TCEHSSEAKA FHDYSAAAAP SPVLGNIPPG DGMPVGPVPP GFFQPFMSPR YPGGPRPPLR IPNQALGGVP GSQPLLPSGM DPTRQQGHPN MGGPMQRMTP PRGMVPLGPQ NYGGAMRPPL NALGGPGMPG MNMGPGGGRP WPNPTNANSI PYSSASPGNY VGPPGGGGPP GTPIMPSPAD STNSGDNMYT LMNAVPPGPN RPNFPMGPGS DGPMGGLGGM ESHHMNGSLG SGDMDSISKN SPNNMSLSNQ PGTPRDDGEM GGNFLNPFQS ESYSPSMTMS V
Genular Protein ID: 495676621
Symbol: A0A087X159_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 369
- Mass: 38755
- Checksum: 1DDB6F33B471E6B8
- Sequence:
MYGKGKSNSS AVPSDSQARE KLALYVYEYL LHVGAQKSAQ TFLSEIRWEK NITLGEPPGF LHSWWCVFWD LYCAAPERRE TCEHSSEAKA FHDYSAAAAP SPVLGNIPPG DGMPVGPVPP GFFQPFMSPR YPGGPRPPLR IPNQALGGVP GSQPLLPSGM DPTRQQGHPN MGGPMQRMTP PRGMVPLGPQ SDPWLSLQNY GGAMRPPLNA LGGPGMPGMN MGPGGGRPWP NPTNANSIPY SSASPGNYVG PPGGGGPPGT PIMPSPADST NSGDNMYTLM NAVPPGPNRP NFPMGPGSDG PMGGLGGMES HHMNGSLGSG DMDSISKNSP NNMSLSNQPG TPRDDGEMGG NFLNPFQSES YSPSMTMSV