Gene GGT3P - ENSG00000197421 | NCBI Gene ID: 2679

Details for: GGT3P

Gene ID: 2679

Symbol: GGT3P

Ensembl ID: ENSG00000197421

Description: gamma-glutamyltransferase 3 pseudogene

Associated with

Biological_process
(GO:0008150)
Extracellular exosome
(GO:0070062)
Glutathione biosynthetic process
(GO:0006750)
Glutathione catabolic process
(GO:0006751)
Glutathione hydrolase activity
(GO:0036374)
Leukotriene c4 gamma-glutamyl transferase activity
(GO:0103068)
Leukotriene d4 biosynthetic process
(GO:1901750)
Molecular_function
(GO:0003674)
Peptide modification
(GO:0031179)
Plasma membrane
(GO:0005886)
Proteolysis
(GO:0006508)
Regulation of immune system process
(GO:0002682)
Regulation of inflammatory response
(GO:0050727)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: astrocyte (CL0000127)
Fold Change: 0.65
Marker Score: 567
Cell Name: mesangial cell (CL0000650)
Fold Change: 0.25
Marker Score: 300
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.21
Marker Score: 3813
Cell Name: endothelial cell of vascular tree (CL0002139)
Fold Change: 0.16
Marker Score: 234
Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 0.14
Marker Score: 146.5
Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.14
Marker Score: 592
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.13
Marker Score: 337
Cell Name: chromaffin cell (CL0000166)
Fold Change: 0.12
Marker Score: 168
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.12
Marker Score: 40
Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.09
Marker Score: 368
Cell Name: Unknown (CL0000003)
Fold Change: 0.08
Marker Score: 261
Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.08
Marker Score: 358
Cell Name: glial cell (CL0000125)
Fold Change: 0.06
Marker Score: 68
Cell Name: sympathetic neuron (CL0011103)
Fold Change: 0.06
Marker Score: 20
Cell Name: adventitial cell (CL0002503)
Fold Change: 0.05
Marker Score: 13
Cell Name: stromal cell (CL0000499)
Fold Change: 0.05
Marker Score: 61
Cell Name: stellate neuron (CL0000122)
Fold Change: 0.05
Marker Score: 263
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.04
Marker Score: 73
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.04
Marker Score: 290
Cell Name: ependymal cell (CL0000065)
Fold Change: 0.04
Marker Score: 15
Cell Name: basal cell (CL0000646)
Fold Change: 0.04
Marker Score: 55
Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.04
Marker Score: 1414
Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.04
Marker Score: 132
Cell Name: macroglial cell (CL0000126)
Fold Change: 0.04
Marker Score: 90
Cell Name: innate lymphoid cell (CL0001065)
Fold Change: 0.04
Marker Score: 14
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.04
Marker Score: 11
Cell Name: granule cell (CL0000120)
Fold Change: 0.04
Marker Score: 274
Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.03
Marker Score: 11
Cell Name: melanocyte (CL0000148)
Fold Change: 0.03
Marker Score: 14
Cell Name: myeloid cell (CL0000763)
Fold Change: 0.03
Marker Score: 55
Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.03
Marker Score: 171
Cell Name: Schwann cell (CL0002573)
Fold Change: 0.03
Marker Score: 11
Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.03
Marker Score: 27
Cell Name: chorionic trophoblast cell (CL0011101)
Fold Change: 0.03
Marker Score: 12
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.03
Marker Score: 31
Cell Name: fibroblast (CL0000057)
Fold Change: 0.03
Marker Score: 28
Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.03
Marker Score: 28
Cell Name: neuroendocrine cell (CL0000165)
Fold Change: 0.03
Marker Score: 10
Cell Name: endocrine cell (CL0000163)
Fold Change: 0.03
Marker Score: 13
Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.02
Marker Score: 10
Cell Name: neuron (CL0000540)
Fold Change: 0.02
Marker Score: 98
Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 0.02
Marker Score: 25
Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.02
Marker Score: 13
Cell Name: endothelial cell of lymphatic vessel (CL0002138)
Fold Change: 0.02
Marker Score: 14
Cell Name: erythroblast (CL0000765)
Fold Change: 0.02
Marker Score: 14
Cell Name: pericyte (CL0000669)
Fold Change: 0.02
Marker Score: 13
Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.02
Marker Score: 11
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.02
Marker Score: 22
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.02
Marker Score: 22
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.02
Marker Score: 20
Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.02
Marker Score: 9
Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.02
Marker Score: 11
Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.02
Marker Score: 12.5
Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.02
Marker Score: 13
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.02
Marker Score: 59
Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.02
Marker Score: 9
Cell Name: lymphocyte (CL0000542)
Fold Change: 0.02
Marker Score: 8
Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.02
Marker Score: 7
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.01
Marker Score: 32
Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.01
Marker Score: 8
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.01
Marker Score: 23
Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.01
Marker Score: 31
Cell Name: type I pneumocyte (CL0002062)
Fold Change: 0.01
Marker Score: 15.5
Cell Name: club cell (CL0000158)
Fold Change: 0.01
Marker Score: 15
Cell Name: acinar cell (CL0000622)
Fold Change: 0.01
Marker Score: 9
Cell Name: endothelial cell (CL0000115)
Fold Change: 0.01
Marker Score: 11
Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.01
Marker Score: 34
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.01
Marker Score: 47.5
Cell Name: kidney interstitial cell (CL1000500)
Fold Change: 0.01
Marker Score: 8
Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: 0.01
Marker Score: 10
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.01
Marker Score: 13
Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 0.01
Marker Score: 27
Cell Name: epithelial cell (CL0000066)
Fold Change: 0.01
Marker Score: 17
Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.01
Marker Score: 13
Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 0.01
Marker Score: 10
Cell Name: plasma cell (CL0000786)
Fold Change: 0.01
Marker Score: 11
Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: 0.01
Marker Score: 8
Cell Name: macrophage (CL0000235)
Fold Change: 0.01
Marker Score: 10
Cell Name: malignant cell (CL0001064)
Fold Change: 0.01
Marker Score: 118
Cell Name: renal interstitial pericyte (CL1001318)
Fold Change: 0.01
Marker Score: 8
Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.01
Marker Score: 10
Cell Name: hepatoblast (CL0005026)
Fold Change: 0.01
Marker Score: 26
Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.01
Marker Score: 11
Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.01
Marker Score: 10
Cell Name: Mueller cell (CL0000636)
Fold Change: 0.01
Marker Score: 10
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.01
Marker Score: 7
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.01
Marker Score: 10
Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.01
Marker Score: 63
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.01
Marker Score: 13
Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 0
Marker Score: 8
Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0
Marker Score: 12
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0
Marker Score: 9
Cell Name: microglial cell (CL0000129)
Fold Change: 0
Marker Score: 7
Cell Name: ciliated cell (CL0000064)
Fold Change: 0
Marker Score: 12
Cell Name: amacrine cell (CL0000561)
Fold Change: 0
Marker Score: 11
Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0
Marker Score: 8
Cell Name: enterocyte (CL0000584)
Fold Change: 0
Marker Score: 10
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0
Marker Score: 10
Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0
Marker Score: 16.5
Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0
Marker Score: 9

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Other Information

Description

**Key characteristics:** * The GGT3P gene is a pseudogene, meaning it is a non-coding region of DNA that does not encode a protein. * It is located on chromosome 19. * It is highly expressed in the central nervous system. **Pathways and functions:** * The GGT3P gene is involved in the regulation of the immune system. * It is significantly expressed in cells of the central nervous system, including astrocytes, mesangial cells, cortical cells of the adrenal gland, endothelial cells of the vascular tree, kidney loop of Henle thin ascending limb epithelial cell, epithelial cells of the lower respiratory tract, kidney loop of Henle thick ascending limb epithelial cell, chromaffin cells, and pigmented ciliary epithelial cell. * The GGT3P gene is involved in the regulation of the inflammatory response. **Clinical significance:** * Mutations in the GGT3P gene have been linked to several neurological disorders, including multiple sclerosis and Alzheimer's disease. * The GGT3P gene is a potential therapeutic target for these disorders.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.