Details for: SNORD41

Gene ID: 26810

Symbol: SNORD41

Ensembl ID: ENSG00000209702

Description: small nucleolar RNA, C/D box 41

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1390
    Cell Significance Index: 1.9800
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.0022
    Cell Significance Index: -0.0200
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0087
    Cell Significance Index: -0.0800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0712
    Cell Significance Index: -1.0700
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.1220
    Cell Significance Index: -1.5300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1271
    Cell Significance Index: -1.5200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SNORD41 is a 21-nucleotide C/D box snoRNA, which is characterized by its unique secondary structure and the presence of a C/D box motif. This snoRNA is highly conserved across species, suggesting its important role in RNA processing and cellular differentiation. SNORD41 is specifically expressed in cells that undergo significant differentiation and development, such as neuronal receptor cells, smooth muscle myoblasts, and cardiac endothelial cells. **Pathways and Functions:** SNORD41 is involved in the regulation of RNA processing, specifically in the modification of rRNA and other RNA molecules. The exact mechanisms by which SNORD41 exerts its functions are not fully understood, but it is thought to interact with other RNA-binding proteins to modulate RNA processing events. SNORD41 has been implicated in the regulation of cellular differentiation, with studies suggesting that it plays a role in the development of neuronal receptor cells, smooth muscle myoblasts, and cardiac endothelial cells. Additionally, SNORD41 may be involved in the regulation of immune cell development, particularly in the differentiation of lymphoid lineage-restricted progenitor cells. **Clinical Significance:** The clinical significance of SNORD41 is an area of ongoing research. However, given its expression in various cell types, including those involved in cardiovascular disease, it is possible that SNORD41 plays a role in the development of cardiac conditions such as heart failure and atherosclerosis. Furthermore, SNORD41 may be involved in the regulation of immune cell development, which could have implications for the treatment of autoimmune diseases. Future studies are needed to fully elucidate the clinical significance of SNORD41 and its potential as a therapeutic target. In conclusion, SNORD41 is a small nucleolar RNA that plays a crucial role in RNA processing and cellular differentiation. Its unique expression pattern and involvement in various cellular processes make it an attractive target for further research. As our understanding of SNORD41 continues to evolve, it is likely that we will uncover new insights into its clinical significance and potential therapeutic applications.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.