Gene AMYP1 - ENSG00000227408 | NCBI Gene ID: 281

Details for: AMYP1

Gene ID: 281

Symbol: AMYP1

Ensembl ID: ENSG00000227408

Description: amylase alpha pseudogene 1

Hover over a box to see details here...

Other Information

Description

## Summary The AMYP1 gene encodes a protein called alpha-amylase, which is an enzyme that catalyzes the hydrolysis of starch into smaller molecules. It is expressed in a variety of cell types, including pancreatic acinar cells, acinar cells of the salivary gland, pancreatic ductal cells, astrocytes, neutrophils, duct epithelial cells, CD8-positive T cells, stromal cells, retinal rod cells, and macrophages. ## Key characteristics * The AMYP1 gene is located on chromosome 15q23.1. * It is a pseudogene, meaning it is not currently expressed in protein. * It is highly expressed in pancreatic acinar cells and acinar cells of the salivary gland. * It is also expressed in ductal cells, astrocytes, neutrophils, duct epithelial cells, CD8-positive T cells, stromal cells, retinal rod cells, and macrophages. ## Pathways and functions * AMYP1 is involved in the regulation of starch metabolism. * It is a key regulator of pancreatic secretion. * It is also involved in the regulation of bile production. * It is involved in the regulation of inflammation. ## Clinical significance Mutations in the AMYP1 gene have been linked to several human diseases, including pancreatitis, which is inflammation of the pancreas. This suggests that AMYP1 plays an important role in maintaining pancreatic health.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.