Details for: RNU7 68P

Gene ID: 6072

Symbol: RNU7 68P

Ensembl ID: ENSG00000251707

Description: RNA, U7 small nuclear 68 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0017
    Cell Significance Index: -0.0300
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: -0.0046
    Cell Significance Index: -0.0400
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0101
    Cell Significance Index: -0.1300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0105
    Cell Significance Index: -0.1100
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0123
    Cell Significance Index: -0.1300
  • Cell Name: cerebellar neuron (CL1001611)
    Fold Change: -0.0185
    Cell Significance Index: -0.1300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** RNU7 68P is predominantly expressed in stromal cells, enterocytes, and Purkinje cells, suggesting a specific role in tissue maintenance, immune regulation, and neuronal function. 2. **Pseudogene Status:** As a pseudogene, RNU7 68P lacks the ability to produce a functional protein, but its expression is not entirely eliminated, indicating a possible regulatory or modulatory function. 3. **Sequence Homology:** RNU7 68P shares sequence homology with the U7 small nuclear RNA (snoRNA), suggesting a potential role in RNA processing and modification. **Pathways and Functions:** 1. **RNA Processing and Modification:** RNU7 68P may play a role in regulating RNA processing and modification, particularly in the context of U7 snoRNAs. Its sequence homology with U7 snoRNAs suggests a possible involvement in guiding RNA precursors to their correct processing sites. 2. **Immunological Regulation:** RNU7 68P expression in stromal cells and enterocytes implies a potential role in modulating immune responses. Its expression in Purkinje cells suggests a possible involvement in neuronal function and immune regulation. 3. **Cellular Signaling:** RNU7 68P may interact with signaling pathways involved in cell growth, differentiation, and survival. Its expression in stromal cells and enterocytes suggests a possible role in regulating cellular homeostasis. **Clinical Significance:** 1. **Immunological Disorders:** The expression of RNU7 68P in stromal cells and enterocytes suggests a potential role in regulating immune responses. Dysregulation of RNU7 68P expression may contribute to the development of immunological disorders, such as autoimmune diseases or inflammatory conditions. 2. **Neurological Disorders:** The expression of RNU7 68P in Purkinje cells suggests a possible role in regulating neuronal function. Dysregulation of RNU7 68P expression may contribute to the development of neurological disorders, such as neurodegenerative diseases or neurological disorders. 3. **Cancer:** RNU7 68P expression in stromal cells and enterocytes suggests a possible role in regulating cellular homeostasis. Dysregulation of RNU7 68P expression may contribute to the development of cancer, particularly in the context of immune suppression and tumor microenvironment regulation. In conclusion, RNU7 68P is a complex pseudogene with a unique expression profile and potential role in immunological processes. Further research is necessary to fully elucidate the functions and clinical significance of RNU7 68P, but its involvement in RNA processing, immunological regulation, and neuronal function suggests a promising area of investigation in the field of immunology and molecular biology.

Database document:

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