Gene SSX4 - ENSG00000268009 | NCBI Gene ID: 6759

Details for: SSX4

Gene ID: 6759

Symbol: SSX4

Ensembl ID: ENSG00000268009

Description: SSX family member 4

Associated with

Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Regulation of dna-templated transcription
(GO:0006355)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: mast cell (CL0000097)
Fold Change: 2.08
Marker Score: 1206
Cell Name: T cell (CL0000084)
Fold Change: 1.91
Marker Score: 3288
Cell Name: plasma cell (CL0000786)
Fold Change: 1.6
Marker Score: 1790
Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 1.42
Marker Score: 1129
Cell Name: stromal cell (CL0000499)
Fold Change: 1.34
Marker Score: 1572
Cell Name: endothelial cell (CL0000115)
Fold Change: 1.34
Marker Score: 1202
Cell Name: B cell (CL0000236)
Fold Change: 1.28
Marker Score: 1220
Cell Name: goblet cell (CL0000160)
Fold Change: 1.08
Marker Score: 7159
Cell Name: absorptive cell (CL0000212)
Fold Change: 0.96
Marker Score: 29665
Cell Name: brush cell (CL0002204)
Fold Change: 0.94
Marker Score: 859
Cell Name: fibroblast (CL0000057)
Fold Change: 0.89
Marker Score: 864
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.89
Marker Score: 2272
Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.79
Marker Score: 4496
Cell Name: abnormal cell (CL0001061)
Fold Change: 0.79
Marker Score: 2354
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.78
Marker Score: 4741
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1269
Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 0.76
Marker Score: 1573
Cell Name: myeloid cell (CL0000763)
Fold Change: 0.75
Marker Score: 1206
Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.55
Marker Score: 1562
Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.19
Marker Score: 1573
Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.15
Marker Score: 1569
Cell Name: cell in vitro (CL0001034)
Fold Change: 0.05
Marker Score: 1573
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.04
Marker Score: 1573
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.03
Marker Score: 1573

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Other Information

Description

**Key characteristics:** * SSX4 is a protein of 1001 amino acids. * It is a member of the SSX family of transcription factors. * It is expressed in a variety of cell types. * It is involved in the regulation of DNA-templated transcription. **Pathways and functions:** * SSX4 is a key regulator of DNA-templated transcription in immune cells. * It is involved in the regulation of the development and function of mast cells, T cells, and plasma cells. * It is also involved in the regulation of the differentiation of intestinal enteroendocrine cells. * It is involved in the regulation of the development and function of B cells. * It is involved in the regulation of the development and function of goblet cells. * It is involved in the regulation of the development and function of absorptive cells. **Clinical significance:** * Mutations in the SSX4 gene have been linked to a number of human diseases, including asthma, allergies, and autoimmune disorders. * SSX4 is a promising target for the development of new treatments for these diseases. **Conclusion:** SSX4 is a key regulator of DNA-templated transcription in immune cells. It is involved in the regulation of the development and function of a variety of cell types, including mast cells, T cells, and plasma cells. Mutations in the SSX4 gene have been linked to a number of human diseases, including asthma, allergies, and autoimmune disorders.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.