Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 2862
{
"geneID": 2862,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AL137000.6"
]
},
"genePos": {
"start": 5001,
"end": 7040
},
"orientation": true,
"symbol": "MLNR",
"created": {
"$date": {
"$numberLong": "1738333348838"
}
},
"crossReference": {
"enseGeneID": "ENSG00000102539",
"enseRnaID": [
"ENST00000218721.1"
],
"enseProtID": [
"ENSP00000218721.1"
]
},
"chrom": {
"pos": "13",
"type": 1,
"loc": "13q14.2"
},
"desc": "motilin receptor",
"geneType": 5,
"mim": [
{
"id": 602885,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-162582",
"term": "Signal Transduction",
"cat": 10
},
{
"id": "R-HSA-372790",
"term": "Signaling by GPCR",
"cat": 11
},
{
"id": "R-HSA-388396",
"term": "GPCR downstream signalling",
"cat": 12
},
{
"id": "R-HSA-500792",
"term": "GPCR ligand binding",
"cat": 12
},
{
"id": "R-HSA-373076",
"term": "Class A/1 (Rhodopsin-like receptors)",
"cat": 13
},
{
"id": "R-HSA-416476",
"term": "G alpha (q) signalling events",
"cat": 13
},
{
"id": "R-HSA-375276",
"term": "Peptide ligand-binding receptors",
"cat": 14
},
{
"id": "GO:0008528",
"term": "G protein-coupled peptide receptor activity",
"cat": 0
},
{
"id": "GO:0008528",
"term": "G protein-coupled peptide receptor activity",
"pubMed": [
10381885
],
"cat": 0
},
{
"id": "GO:0042562",
"term": "hormone binding",
"pubMed": [
10381885
],
"cat": 0
},
{
"id": "GO:0007186",
"term": "G protein-coupled receptor signaling pathway",
"cat": 1
},
{
"id": "GO:0005829",
"term": "cytosol",
"cat": 2
},
{
"id": "GO:0005886",
"term": "plasma membrane",
"cat": 2
}
],
"protein": [
{
"symbol": "MTLR_HUMAN",
"name": "Motilin receptor",
"accession": [
"O43193"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AF034632",
"AY603964",
"AL137000"
],
"CCDS": [
"CCDS9414.1"
],
"RefSeq": [
"NP_001498.1"
],
"PDB": [
"8IBU",
"8IBV"
],
"PDBsum": [
"8IBU",
"8IBV"
],
"AlphaFoldDB": [
"O43193"
],
"EMDB": [
"EMD-35345",
"EMD-35346"
],
"SMR": [
"O43193"
],
"BioGRID": [
"109120"
],
"IntAct": [
"O43193"
],
"STRING": [
"9606.ENSP00000218721"
],
"BindingDB": [
"O43193"
],
"ChEMBL": [
"CHEMBL2203"
],
"DrugBank": [
"DB00199",
"DB06587"
],
"DrugCentral": [
"O43193"
],
"GuidetoPHARMACOLOGY": [
"297"
],
"GlyCosmos": [
"O43193"
],
"GlyGen": [
"O43193"
],
"iPTMnet": [
"O43193"
],
"PhosphoSitePlus": [
"O43193"
],
"BioMuta": [
"MLNR"
],
"MassIVE": [
"O43193"
],
"PaxDb": [
"9606-ENSP00000218721"
],
"PeptideAtlas": [
"O43193"
],
"ProteomicsDB": [
"48807",
"48808"
],
"Antibodypedia": [
"42284"
],
"DNASU": [
"2862"
],
"Ensembl": [
"ENST00000218721.1"
],
"KEGG": [
"hsa:2862"
],
"MANE-Select": [
"ENST00000218721.1"
],
"UCSC": [
"uc010tgj.2"
],
"AGR": [
"HGNC:4495"
],
"CTD": [
"2862"
],
"DisGeNET": [
"2862"
],
"GeneCards": [
"MLNR"
],
"HGNC": [
"HGNC:4495"
],
"HPA": [
"ENSG00000102539"
],
"MIM": [
"602885"
],
"neXtProt": [
"NX_O43193"
],
"OpenTargets": [
"ENSG00000102539"
],
"PharmGKB": [
"PA28884"
],
"VEuPathDB": [
"HostDB:ENSG00000102539"
],
"eggNOG": [
"KOG3656"
],
"GeneTree": [
"ENSGT01120000271823"
],
"HOGENOM": [
"CLU_009579_6_5_1"
],
"InParanoid": [
"O43193"
],
"OMA": [
"ERRCSPF"
],
"OrthoDB": [
"3471593at2759"
],
"PhylomeDB": [
"O43193"
],
"TreeFam": [
"TF336314"
],
"PathwayCommons": [
"O43193"
],
"Reactome": [
"R-HSA-375276",
"R-HSA-416476"
],
"SignaLink": [
"O43193"
],
"SIGNOR": [
"O43193"
],
"BioGRID-ORCS": [
"2862"
],
"GeneWiki": [
"Motilin_receptor"
],
"GenomeRNAi": [
"2862"
],
"Pharos": [
"O43193"
],
"PRO": [
"PR:O43193"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"O43193"
],
"Bgee": [
"ENSG00000102539"
],
"GO": [
"GO:0005829",
"GO:0005886",
"GO:0008528",
"GO:0042562",
"GO:0007186"
],
"Gene3D": [
"1.20.1070.10"
],
"InterPro": [
"IPR003905",
"IPR000276",
"IPR017452"
],
"PANTHER": [
"PTHR24243",
"PTHR24243:SF3"
],
"Pfam": [
"PF00001"
],
"PRINTS": [
"PR01417",
"PR00237"
],
"SMART": [
"SM01381"
],
"SUPFAM": [
"SSF81321"
],
"PROSITE": [
"PS00237",
"PS50262"
]
},
"citations": [
{
"title": "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.",
"pubmedID": "9441746",
"doi": "10.1006/geno.1997.5069"
},
{
"title": "Receptor for motilin identified in the human gastrointestinal system.",
"pubmedID": "10381885",
"doi": "10.1126/science.284.5423.2184"
},
{
"title": "The DNA sequence and analysis of human chromosome 13.",
"pubmedID": "15057823",
"doi": "10.1038/nature02379"
},
{
"title": "Growth hormone secretagogue receptor family members and ligands.",
"pubmedID": "11322507",
"doi": "10.1385/endo:14:1:009"
}
],
"sequence": {
"length": 412,
"mass": 45344,
"checksum": "C13FF6165012DEF3",
"modified": {
"$date": {
"$numberLong": "896659200000"
}
},
"version": 1,
"sequence": "MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG"
},
"existence": 0,
"relevance": 1,
"proteinID": 1426992874
}
]
}