Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 3444
{
"geneID": 3444,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AL512606.6"
]
},
"genePos": {
"start": 21201469,
"end": 21202205
},
"orientation": false,
"symbol": "IFNA7",
"created": {
"$date": {
"$numberLong": "1738333348931"
}
},
"crossReference": {
"enseGeneID": "ENSG00000214042",
"enseRnaID": [
"ENST00000239347.3"
],
"enseProtID": [
"ENSP00000239347.3"
]
},
"chrom": {
"pos": "9",
"type": 1,
"loc": "9p21.3"
},
"desc": "interferon alpha 7",
"geneType": 5,
"mim": [
{
"id": 147567,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-109582",
"term": "Hemostasis",
"cat": 10
},
{
"id": "R-HSA-1643685",
"term": "Disease",
"cat": 10
},
{
"id": "R-HSA-168256",
"term": "Immune System",
"cat": 10
},
{
"id": "R-HSA-1280215",
"term": "Cytokine Signaling in Immune system",
"cat": 11
},
{
"id": "R-HSA-168249",
"term": "Innate Immune System",
"cat": 11
},
{
"id": "R-HSA-5663205",
"term": "Infectious disease",
"cat": 11
},
{
"id": "R-HSA-983231",
"term": "Factors involved in megakaryocyte development and platelet production",
"cat": 11
},
{
"id": "R-HSA-168928",
"term": "DDX58/IFIH1-mediated induction of interferon-alpha/beta",
"cat": 12
},
{
"id": "R-HSA-913531",
"term": "Interferon Signaling",
"cat": 12
},
{
"id": "R-HSA-9824446",
"term": "Viral Infection Pathways",
"cat": 12
},
{
"id": "R-HSA-909733",
"term": "Interferon alpha/beta signaling",
"cat": 13
},
{
"id": "R-HSA-933541",
"term": "TRAF6 mediated IRF7 activation",
"cat": 13
},
{
"id": "R-HSA-9679506",
"term": "SARS-CoV Infections",
"cat": 13
},
{
"id": "R-HSA-9820952",
"term": "Respiratory Syncytial Virus Infection Pathway",
"cat": 13
},
{
"id": "R-HSA-912694",
"term": "Regulation of IFNA/IFNB signaling",
"cat": 14
},
{
"id": "R-HSA-9694516",
"term": "SARS-CoV-2 Infection",
"cat": 14
},
{
"id": "R-HSA-9833110",
"term": "RSV-host interactions",
"cat": 14
},
{
"id": "R-HSA-9705683",
"term": "SARS-CoV-2-host interactions",
"cat": 15
},
{
"id": "R-HSA-9833109",
"term": "Evasion by RSV of host interferon responses",
"cat": 15
},
{
"id": "R-HSA-9705671",
"term": "SARS-CoV-2 activates/modulates innate and adaptive immune responses",
"cat": 16
},
{
"id": "GO:0005125",
"term": "cytokine activity",
"cat": 0
},
{
"id": "GO:0005132",
"term": "type I interferon receptor binding",
"cat": 0
},
{
"id": "GO:0002250",
"term": "adaptive immune response",
"cat": 1
},
{
"id": "GO:0002286",
"term": "T cell activation involved in immune response",
"cat": 1
},
{
"id": "GO:0002312",
"term": "B cell activation involved in immune response",
"cat": 1
},
{
"id": "GO:0002323",
"term": "natural killer cell activation involved in immune response",
"cat": 1
},
{
"id": "GO:0006959",
"term": "humoral immune response",
"cat": 1
},
{
"id": "GO:0007267",
"term": "cell-cell signaling",
"pubMed": [
2995168
],
"cat": 1
},
{
"id": "GO:0009615",
"term": "response to virus",
"pubMed": [
2995168
],
"cat": 1
},
{
"id": "GO:0043330",
"term": "response to exogenous dsRNA",
"cat": 1
},
{
"id": "GO:0051607",
"term": "defense response to virus",
"cat": 1
},
{
"id": "GO:0060337",
"term": "type I interferon-mediated signaling pathway",
"cat": 1
},
{
"id": "GO:0060337",
"term": "type I interferon-mediated signaling pathway",
"pubMed": [
30936491
],
"cat": 1
},
{
"id": "GO:0098586",
"term": "cellular response to virus",
"pubMed": [
30936491
],
"cat": 1
},
{
"id": "GO:0005576",
"term": "extracellular region",
"cat": 2
},
{
"id": "GO:0005615",
"term": "extracellular space",
"cat": 2
}
],
"geneRelations": [
{
"type": 8,
"similarGenes": [
"158011"
]
}
],
"protein": [
{
"symbol": "IFNA7_HUMAN",
"name": "Interferon alpha-7",
"accession": [
"P01567",
"Q14607",
"Q5VV14"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"V00531",
"X02960",
"M34913",
"AL512606",
"CH471071",
"BC074991",
"BC074992",
"BC113994",
"BC114000"
],
"CCDS": [
"CCDS34995.1"
],
"PIR": [
"A01831",
"F25843",
"I53102"
],
"RefSeq": [
"NP_066401.2"
],
"AlphaFoldDB": [
"P01567"
],
"SMR": [
"P01567"
],
"BioGRID": [
"109667"
],
"ComplexPortal": [
"CPX-5997"
],
"IntAct": [
"P01567"
],
"STRING": [
"9606.ENSP00000239347"
],
"ChEMBL": [
"CHEMBL3856161"
],
"iPTMnet": [
"P01567"
],
"PhosphoSitePlus": [
"P01567"
],
"BioMuta": [
"IFNA7"
],
"DMDM": [
"124442"
],
"MassIVE": [
"P01567"
],
"PaxDb": [
"9606-ENSP00000239347"
],
"PeptideAtlas": [
"P01567"
],
"ABCD": [
"P01567"
],
"Antibodypedia": [
"24856"
],
"DNASU": [
"3444"
],
"Ensembl": [
"ENST00000239347.3"
],
"KEGG": [
"hsa:3444"
],
"MANE-Select": [
"ENST00000239347.3"
],
"UCSC": [
"uc003zop.1"
],
"AGR": [
"HGNC:5428"
],
"CTD": [
"3444"
],
"GeneCards": [
"IFNA7"
],
"HGNC": [
"HGNC:5428"
],
"HPA": [
"ENSG00000214042"
],
"MIM": [
"147567"
],
"neXtProt": [
"NX_P01567"
],
"OpenTargets": [
"ENSG00000214042"
],
"PharmGKB": [
"PA29667"
],
"VEuPathDB": [
"HostDB:ENSG00000214042"
],
"eggNOG": [
"ENOG502SQAC"
],
"GeneTree": [
"ENSGT01000000214430"
],
"HOGENOM": [
"CLU_109427_0_0_1"
],
"InParanoid": [
"P01567"
],
"OMA": [
"RFPREEM"
],
"OrthoDB": [
"5358931at2759"
],
"PhylomeDB": [
"P01567"
],
"TreeFam": [
"TF336177"
],
"PathwayCommons": [
"P01567"
],
"Reactome": [
"R-HSA-909733",
"R-HSA-912694",
"R-HSA-933541",
"R-HSA-9705671",
"R-HSA-983231",
"R-HSA-9833109"
],
"SignaLink": [
"P01567"
],
"BioGRID-ORCS": [
"3444"
],
"GeneWiki": [
"IFNA7"
],
"GenomeRNAi": [
"3444"
],
"Pharos": [
"P01567"
],
"PRO": [
"PR:P01567"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"P01567"
],
"Bgee": [
"ENSG00000214042"
],
"GO": [
"GO:0005576",
"GO:0005615",
"GO:0005125",
"GO:0005132",
"GO:0002250",
"GO:0030183",
"GO:0042100",
"GO:0007267",
"GO:0098586",
"GO:0019221",
"GO:0051607",
"GO:0006959",
"GO:0002323",
"GO:0033141",
"GO:0043330",
"GO:0009615",
"GO:0002286",
"GO:0060337"
],
"CDD": [
"cd00095"
],
"Gene3D": [
"1.20.1250.10"
],
"InterPro": [
"IPR009079",
"IPR000471"
],
"PANTHER": [
"PTHR11691:SF69",
"PTHR11691"
],
"Pfam": [
"PF00143"
],
"PRINTS": [
"PR00266"
],
"SMART": [
"SM00076"
],
"SUPFAM": [
"SSF47266"
],
"PROSITE": [
"PS00252"
]
},
"citations": [
{
"title": "Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster.",
"pubmedID": "6181262",
"doi": "10.1016/0022-2836(82)90261-3"
},
{
"title": "Structural relationship of human interferon alpha genes and pseudogenes.",
"pubmedID": "4057246",
"doi": "10.1016/0022-2836(85)90401-2"
},
{
"title": "Cloning, expression and biological activity of a new variant of human interferon alpha identified in virus induced lymphoblastoid cells.",
"pubmedID": "2995168"
},
{
"title": "DNA sequence and analysis of human chromosome 9.",
"pubmedID": "15164053",
"doi": "10.1038/nature02465"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
},
{
"title": "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes.",
"pubmedID": "9425112",
"doi": "10.1042/bj3290295"
},
{
"title": "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population.",
"pubmedID": "8910771",
"doi": "10.1089/jir.1996.16.853"
}
],
"sequence": {
"length": 189,
"mass": 22107,
"checksum": "9DF6F5C81E339A42",
"modified": {
"$date": {
"$numberLong": "522288000000"
}
},
"version": 1,
"sequence": "MARSFSLLMVVLVLSYKSICSLGCDLPQTHSLRNRRALILLAQMGRISPFSCLKDRHEFRFPEEEFDGHQFQKTQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDFILAVRKYFQRITLYLMEKKYSPCAWEVVRAEIMRSFSFSTNLKKGLRRKD"
},
"existence": 0,
"relevance": 1,
"proteinID": 1015579354
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}