Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 417
{
"geneID": 417,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC060812.15"
]
},
"genePos": {
"start": 3645128,
"end": 3664416
},
"orientation": false,
"symbol": "ART1",
"created": {
"$date": {
"$numberLong": "1738333348667"
}
},
"crossReference": {
"enseGeneID": "ENSG00000129744",
"enseRnaID": [
"ENST00000250693.2"
],
"enseProtID": [
"ENSP00000250693.1"
]
},
"chrom": {
"pos": "11",
"type": 1,
"loc": "11p15.4"
},
"desc": "ADP-ribosyltransferase 1",
"geneType": 5,
"mim": [
{
"id": 601625,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-168256",
"term": "Immune System",
"cat": 10
},
{
"id": "R-HSA-168249",
"term": "Innate Immune System",
"cat": 11
},
{
"id": "R-HSA-6803157",
"term": "Antimicrobial peptides",
"cat": 12
},
{
"id": "R-HSA-1461973",
"term": "Defensins",
"cat": 13
},
{
"id": "R-HSA-1462054",
"term": "Alpha-defensins",
"cat": 14
},
{
"id": "GO:0003950",
"term": "NAD+-protein poly-ADP-ribosyltransferase activity",
"cat": 0
},
{
"id": "GO:0016779",
"term": "nucleotidyltransferase activity",
"cat": 0
},
{
"id": "GO:0106274",
"term": "NAD+-protein-arginine ADP-ribosyltransferase activity",
"cat": 0
},
{
"id": "GO:0005886",
"term": "plasma membrane",
"cat": 2
},
{
"id": "GO:0009986",
"term": "cell surface",
"cat": 2
},
{
"id": "GO:0033017",
"term": "sarcoplasmic reticulum membrane",
"cat": 2
},
{
"id": "GO:0098552",
"term": "side of membrane",
"cat": 2
}
],
"protein": [
{
"symbol": "NAR1_HUMAN",
"name": "GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1",
"accession": [
"P52961",
"Q6NTD2",
"Q96KT9"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"Rhea": [
"RHEA:19149",
"RHEA-COMP:10532",
"RHEA-COMP:15087"
],
"ChEBI": [
"CHEBI:15378",
"CHEBI:17154",
"CHEBI:29965",
"CHEBI:57540",
"CHEBI:142554",
"CHEBI:57540",
"CHEBI:57540",
"CHEBI:57540"
],
"EC": [
"2.4.2.31",
"2.4.2.31"
],
"EMBL": [
"S74683",
"CH471158",
"BC069102",
"BC111729",
"AJ291430"
],
"CCDS": [
"CCDS7744.1"
],
"PIR": [
"A55966"
],
"RefSeq": [
"NP_004305.2",
"XP_011518416.1",
"XP_016873252.1"
],
"AlphaFoldDB": [
"P52961"
],
"SMR": [
"P52961"
],
"BioGRID": [
"106910"
],
"IntAct": [
"P52961"
],
"STRING": [
"9606.ENSP00000250693"
],
"ChEMBL": [
"CHEMBL2158"
],
"DrugBank": [
"DB01854"
],
"GlyCosmos": [
"P52961"
],
"GlyGen": [
"P52961"
],
"PhosphoSitePlus": [
"P52961"
],
"BioMuta": [
"ART1"
],
"DMDM": [
"206729882"
],
"MassIVE": [
"P52961"
],
"PaxDb": [
"9606-ENSP00000250693"
],
"PeptideAtlas": [
"P52961"
],
"Antibodypedia": [
"23357"
],
"DNASU": [
"417"
],
"Ensembl": [
"ENST00000250693.2"
],
"KEGG": [
"hsa:417"
],
"MANE-Select": [
"ENST00000250693.2"
],
"UCSC": [
"uc001lye.1"
],
"AGR": [
"HGNC:723"
],
"CTD": [
"417"
],
"DisGeNET": [
"417"
],
"GeneCards": [
"ART1"
],
"HGNC": [
"HGNC:723"
],
"HPA": [
"ENSG00000129744"
],
"MIM": [
"601625"
],
"neXtProt": [
"NX_P52961"
],
"OpenTargets": [
"ENSG00000129744"
],
"PharmGKB": [
"PA25014"
],
"VEuPathDB": [
"HostDB:ENSG00000129744"
],
"eggNOG": [
"ENOG502QUE9"
],
"GeneTree": [
"ENSGT01030000234601"
],
"HOGENOM": [
"CLU_059744_1_0_1"
],
"InParanoid": [
"P52961"
],
"OMA": [
"FETFQVV"
],
"OrthoDB": [
"2897283at2759"
],
"PhylomeDB": [
"P52961"
],
"TreeFam": [
"TF335356"
],
"BRENDA": [
"2.4.2.31"
],
"PathwayCommons": [
"P52961"
],
"Reactome": [
"R-HSA-1462054"
],
"SignaLink": [
"P52961"
],
"BioGRID-ORCS": [
"417"
],
"ChiTaRS": [
"ART1"
],
"GenomeRNAi": [
"417"
],
"Pharos": [
"P52961"
],
"PRO": [
"PR:P52961"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"P52961"
],
"Bgee": [
"ENSG00000129744"
],
"GO": [
"GO:0009986",
"GO:0005886",
"GO:0033017",
"GO:0098552",
"GO:0003950",
"GO:0106274",
"GO:0016779"
],
"InterPro": [
"IPR050999",
"IPR000768"
],
"PANTHER": [
"PTHR10339",
"PTHR10339:SF19"
],
"Pfam": [
"PF01129"
],
"PRINTS": [
"PR00970"
],
"SUPFAM": [
"SSF56399"
],
"PROSITE": [
"PS01291",
"PS51996"
]
},
"citations": [
{
"title": "Immunological and structural conservation of mammalian skeletal muscle glycosylphosphatidylinositol-linked ADP-ribosyltransferases.",
"pubmedID": "7947688",
"doi": "10.1021/bi00209a014"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
},
{
"title": "Toward a unified nomenclature for mammalian ADP-ribosyltransferases.",
"pubmedID": "20106667",
"doi": "10.1016/j.tibs.2009.12.003"
},
{
"title": "Glucagon like-peptide-1 receptor is covalently modified by endogenous mono-ADP-ribosyltransferase.",
"pubmedID": "21901419",
"doi": "10.1007/s11033-011-1225-0"
}
],
"sequence": {
"length": 327,
"mass": 36335,
"checksum": "8FDC568197031EA5",
"modified": {
"$date": {
"$numberLong": "1222128000000"
}
},
"version": 2,
"sequence": "MQMPAMMSLLLVSVGLMEALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNSAMGQSPLSAVWSLLLLLWFLVVRAFPDGPGLL"
},
"existence": 0,
"relevance": 1,
"proteinID": 1059495894
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}