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Raw Database JSON for Gene ID: 474343
{
"geneID": 474343,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AL022157.1"
]
},
"genePos": {
"start": 57119682,
"end": 57121548
},
"orientation": true,
"symbol": "SPIN2B",
"created": {
"$date": {
"$numberLong": "1738333350703"
}
},
"crossReference": {
"enseGeneID": "ENSG00000186787",
"enseRnaID": [
"ENST00000434397.3"
],
"enseProtID": [
"ENSP00000404314.2"
]
},
"chrom": {
"loc": "Xp11.21"
},
"desc": "spindlin family member 2B",
"geneType": 5,
"mim": [
{
"id": 300517,
"relation": 0
}
],
"ontology": [
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
29061846,
32814053
],
"cat": 0
},
{
"id": "GO:0035064",
"term": "methylated histone binding",
"cat": 0
},
{
"id": "GO:0035064",
"term": "methylated histone binding",
"pubMed": [
29061846
],
"cat": 0
},
{
"id": "GO:0006355",
"term": "regulation of DNA-templated transcription",
"cat": 1
},
{
"id": "GO:0006915",
"term": "apoptotic process",
"cat": 1
},
{
"id": "GO:0007276",
"term": "gamete generation",
"cat": 1
},
{
"id": "GO:0005654",
"term": "nucleoplasm",
"cat": 2
},
{
"id": "GO:0005829",
"term": "cytosol",
"cat": 2
}
],
"geneRelations": [
{
"type": 8,
"similarGenes": [
"100129997"
]
}
],
"protein": [
{
"symbol": "SPI2B_HUMAN",
"name": "Spindlin-2B",
"accession": [
"Q9BPZ2",
"Q7Z2M0"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AF356353",
"AL022157",
"BC000044",
"BC071974"
],
"CCDS": [
"CCDS35311.1"
],
"RefSeq": [
"NP_001006682.1",
"NP_001006683.1",
"NP_001006684.1",
"XP_005262066.2",
"XP_005262067.1",
"XP_011529090.1",
"XP_016885041.1"
],
"PDB": [
"5LUG"
],
"PDBsum": [
"5LUG"
],
"AlphaFoldDB": [
"Q9BPZ2"
],
"SMR": [
"Q9BPZ2"
],
"BioGRID": [
"138877"
],
"IntAct": [
"Q9BPZ2"
],
"STRING": [
"9606.ENSP00000335008"
],
"BindingDB": [
"Q9BPZ2"
],
"ChEMBL": [
"CHEMBL4523440"
],
"GlyGen": [
"Q9BPZ2"
],
"iPTMnet": [
"Q9BPZ2"
],
"PhosphoSitePlus": [
"Q9BPZ2"
],
"BioMuta": [
"SPIN2B"
],
"DMDM": [
"23822181"
],
"jPOST": [
"Q9BPZ2"
],
"MassIVE": [
"Q9BPZ2"
],
"PaxDb": [
"9606-ENSP00000335008"
],
"PeptideAtlas": [
"Q9BPZ2"
],
"ProteomicsDB": [
"78597"
],
"Pumba": [
"Q9BPZ2"
],
"Antibodypedia": [
"26988"
],
"DNASU": [
"474343"
],
"Ensembl": [
"ENST00000275988.5",
"ENST00000333933.3",
"ENST00000434397.3"
],
"KEGG": [
"hsa:474343"
],
"MANE-Select": [
"ENST00000434397.3"
],
"UCSC": [
"uc004duy.5"
],
"AGR": [
"HGNC:33147"
],
"CTD": [
"474343"
],
"GeneCards": [
"SPIN2B"
],
"HGNC": [
"HGNC:33147"
],
"HPA": [
"ENSG00000186787"
],
"MIM": [
"300517"
],
"neXtProt": [
"NX_Q9BPZ2"
],
"PharmGKB": [
"PA162404530"
],
"VEuPathDB": [
"HostDB:ENSG00000186787"
],
"eggNOG": [
"ENOG502QRYD"
],
"GeneTree": [
"ENSGT00950000182925"
],
"HOGENOM": [
"CLU_068595_0_0_1"
],
"InParanoid": [
"Q9BPZ2"
],
"OMA": [
"MKTPNVQ"
],
"OrthoDB": [
"5246248at2759"
],
"PhylomeDB": [
"Q9BPZ2"
],
"TreeFam": [
"TF332665"
],
"PathwayCommons": [
"Q9BPZ2"
],
"SignaLink": [
"Q9BPZ2"
],
"BioGRID-ORCS": [
"474343"
],
"GenomeRNAi": [
"474343"
],
"Pharos": [
"Q9BPZ2"
],
"PRO": [
"PR:Q9BPZ2"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"Q9BPZ2"
],
"Bgee": [
"ENSG00000186787"
],
"ExpressionAtlas": [
"Q9BPZ2"
],
"GO": [
"GO:0005829",
"GO:0005654",
"GO:0035064",
"GO:0006915",
"GO:0007276",
"GO:0006355"
],
"Gene3D": [
"2.80.10.70"
],
"InterPro": [
"IPR003671",
"IPR042567"
],
"PANTHER": [
"PTHR10405",
"PTHR10405:SF13"
],
"Pfam": [
"PF02513"
]
},
"citations": [
{
"title": "Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.",
"pubmedID": "12145692",
"doi": "10.1038/sj.leu.2402557"
},
{
"title": "The DNA sequence of the human X chromosome.",
"pubmedID": "15772651",
"doi": "10.1038/nature03440"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
},
{
"title": "A transcriptional coregulator, SPIN-DOC, attenuates the coactivator activity of Spindlin1.",
"pubmedID": "29061846",
"doi": "10.1074/jbc.m117.814913"
}
],
"sequence": {
"length": 258,
"mass": 29158,
"checksum": "CAD74289970B4BCD",
"modified": {
"$date": {
"$numberLong": "991353600000"
}
},
"version": 1,
"sequence": "MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQVPINPSLYLVKYDGIDCVYGLELHRDERVLSLKILSDRVASSHISDANLANTIIGKAVEHMFEGEHGSKDEWRGMVLAQAPIMKAWFYITYEKDPVLYMYQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKKS"
},
"existence": 0,
"relevance": 1,
"proteinID": 2559330985
},
{
"symbol": "Q5JZB7_HUMAN",
"accession": [
"Q5JZB7"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AL022157",
"CH471154",
"EAW93240.1"
],
"RefSeq": [
"NP_001269390.1",
"NP_001269391.1",
"XP_011529091.1"
],
"ProteomicsDB": [
"63528"
],
"Antibodypedia": [
"26988"
],
"DNASU": [
"474343"
],
"Ensembl": [
"ENST00000374910.3",
"ENSP00000364045.3"
],
"UCSC": [
"uc033ega.2"
],
"CTD": [
"474343"
],
"HGNC": [
"HGNC:33147"
],
"VEuPathDB": [
"HostDB:ENSG00000186787"
],
"GeneTree": [
"ENSGT00950000182925"
],
"HOGENOM": [
"CLU_068595_2_0_1"
],
"OrthoDB": [
"5246248at2759"
],
"BioGRID-ORCS": [
"474343"
],
"Proteomes": [
"UP000005640",
"UP000005640"
],
"Bgee": [
"ENSG00000186787"
],
"GO": [
"GO:0005829",
"GO:0005654",
"GO:0035064",
"GO:0007276"
],
"Gene3D": [
"2.80.10.70"
],
"InterPro": [
"IPR003671",
"IPR042567"
],
"PANTHER": [
"PTHR10405",
"PTHR10405:SF13"
],
"Pfam": [
"PF02513"
],
"ARBA": [
"ARBA00009467"
],
"SAM": [
"MobiDB-lite"
],
"PeptideAtlas": [
"Q5JZB7"
]
},
"citations": [
{
"title": "Initial sequencing and analysis of the human genome.",
"pubmedID": "11237011",
"doi": "10.1038/35057062"
},
{
"title": "The sequence of the human genome.",
"pubmedID": "11181995",
"doi": "10.1126/science.1058040"
},
{
"title": "Finishing the euchromatic sequence of the human genome.",
"pubmedID": "15496913",
"doi": "10.1038/nature03001"
},
{
"title": "The DNA sequence of the human X chromosome.",
"pubmedID": "15772651",
"doi": "10.1038/nature03440"
}
],
"sequence": {
"length": 157,
"mass": 17601,
"checksum": "6F1BD85A01B76F6A",
"modified": {
"$date": {
"$numberLong": "1108425600000"
}
},
"version": 1,
"sequence": "MKTPNAQEAEGQQTRAAAGRATGSANMTKKKVSQKKQRGRPSSQPRRNIVGCRISHGWKEGDEPITQWKGTVLDQLLDDYKEGDLRIMPESSESPPTEREPGGVVDGLIGKHVEYTKEDGSKRIGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKKS"
},
"existence": 0,
"relevance": 2,
"proteinID": 2698099539
}
],
"singleCellExpressions": {
"cellSignificanceIndex": [
{
"cell_id": "CL0000936",
"cell_term": "early lymphoid progenitor",
"context": "overall",
"pVal": 0.673430495735682,
"deltaVal": 1,
"csiScore": 3.9031079246859015,
"rCsiScore": 3.4280299556778235,
"prsScore": 99.0198
},
{
"cell_id": "CL0000751",
"cell_term": "rod bipolar cell",
"context": "overall",
"pVal": 0.6799218270513046,
"deltaVal": 1,
"csiScore": 3.1563272513243086,
"rCsiScore": 5.671714089597134,
"prsScore": 95.7924
},
{
"cell_id": "CL0000037",
"cell_term": "hematopoietic stem cell",
"context": "overall",
"pVal": 0.7048282565426909,
"deltaVal": 1,
"csiScore": 3.0419917237636525,
"rCsiScore": 2.0219117847310084,
"prsScore": 98.6013
},
{
"cell_id": "CL0002504",
"cell_term": "enteric smooth muscle cell",
"context": "overall",
"pVal": 0.6760284251570976,
"deltaVal": 1,
"csiScore": 2.697830452029971,
"rCsiScore": 3.850094632638056,
"prsScore": 98.5224
},
{
"cell_id": "CL0000050",
"cell_term": "megakaryocyte-erythroid progenitor cell",
"context": "overall",
"pVal": 0.7120694305278654,
"deltaVal": 1,
"csiScore": 2.4258333571367365,
"rCsiScore": 2.190668596822672,
"prsScore": 97.977
},
{
"cell_id": "CL4023064",
"cell_term": "caudal ganglionic eminence derived cortical interneuron",
"context": "overall",
"pVal": 0.7066488850626886,
"deltaVal": 1,
"csiScore": 1.6761139739314947,
"rCsiScore": 2.960117773019272,
"prsScore": 93.9722
},
{
"cell_id": "CL0008019",
"cell_term": "mesenchymal cell",
"context": "overall",
"pVal": 0.6617334483878652,
"deltaVal": 1,
"csiScore": 1.3194335682589402,
"rCsiScore": 3.3509896018058454,
"prsScore": 97.2354
},
{
"cell_id": "CL0000556",
"cell_term": "megakaryocyte",
"context": "overall",
"pVal": 0.7109108732852247,
"deltaVal": 1,
"csiScore": 0.7837071457319528,
"rCsiScore": 3.400271456578854,
"prsScore": 97.0778
},
{
"cell_id": "CL0000038",
"cell_term": "erythroid progenitor cell",
"context": "overall",
"pVal": 0.6973210999215742,
"deltaVal": 1,
"csiScore": 0.5337583276548535,
"rCsiScore": 3.0601814153548914,
"prsScore": 98.5275
}
]
}
}