Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 5232
{
"geneID": 5232,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AL121974.16"
]
},
"genePos": {
"start": 49785660,
"end": 49787285
},
"orientation": false,
"symbol": "PGK2",
"created": {
"$date": {
"$numberLong": "1738333349081"
}
},
"crossReference": {
"enseGeneID": "ENSG00000170950",
"enseRnaID": [
"ENST00000304801.6"
],
"enseProtID": [
"ENSP00000305995.3"
]
},
"chrom": {
"pos": "6",
"type": 1,
"loc": "6p12.3"
},
"desc": "phosphoglycerate kinase 2",
"geneType": 5,
"mim": [
{
"id": 172270,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-1430728",
"term": "Metabolism",
"cat": 10
},
{
"id": "R-HSA-71387",
"term": "Metabolism of carbohydrates",
"cat": 11
},
{
"id": "R-HSA-70326",
"term": "Glucose metabolism",
"cat": 12
},
{
"id": "R-HSA-70171",
"term": "Glycolysis",
"cat": 13
},
{
"id": "R-HSA-70263",
"term": "Gluconeogenesis",
"cat": 13
},
{
"id": "GO:0004618",
"term": "phosphoglycerate kinase activity",
"pubMed": [
1278465,
5009693
],
"cat": 0
},
{
"id": "GO:0004618",
"term": "phosphoglycerate kinase activity",
"cat": 0
},
{
"id": "GO:0004618",
"term": "phosphoglycerate kinase activity",
"pubMed": [
3453121
],
"cat": 0
},
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
28514442,
33961781,
35271311
],
"cat": 0
},
{
"id": "GO:0005524",
"term": "ATP binding",
"cat": 0
},
{
"id": "GO:0043531",
"term": "ADP binding",
"cat": 0
},
{
"id": "GO:0006094",
"term": "gluconeogenesis",
"cat": 1
},
{
"id": "GO:0006096",
"term": "glycolytic process",
"cat": 1
},
{
"id": "GO:0006096",
"term": "glycolytic process",
"pubMed": [
3453121
],
"cat": 1
},
{
"id": "GO:0016310",
"term": "phosphorylation",
"cat": 1
},
{
"id": "GO:0016310",
"term": "phosphorylation",
"pubMed": [
3453121
],
"cat": 1
},
{
"id": "GO:0030317",
"term": "flagellated sperm motility",
"cat": 1
},
{
"id": "GO:0061621",
"term": "canonical glycolysis",
"cat": 1
},
{
"id": "GO:0005634",
"term": "nucleus",
"pubMed": [
21630459
],
"cat": 2
},
{
"id": "GO:0005829",
"term": "cytosol",
"cat": 2
},
{
"id": "GO:0035686",
"term": "sperm fibrous sheath",
"cat": 2
},
{
"id": "GO:0070062",
"term": "extracellular exosome",
"pubMed": [
23533145
],
"cat": 2
}
],
"protein": [
{
"symbol": "PGK2_HUMAN",
"name": "Phosphoglycerate kinase 2",
"accession": [
"P07205",
"B2R6Y8",
"Q9H107"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"Rhea": [
"RHEA:14801"
],
"ChEBI": [
"CHEBI:30616",
"CHEBI:57604",
"CHEBI:58272",
"CHEBI:456216",
"CHEBI:30616",
"CHEBI:30616",
"CHEBI:30616",
"CHEBI:30616"
],
"EC": [
"2.7.2.3",
"2.7.2.3"
],
"EMBL": [
"X05246",
"AK312770",
"AL121974",
"BC038843"
],
"CCDS": [
"CCDS4930.1"
],
"PIR": [
"A24030",
"A27816"
],
"RefSeq": [
"NP_620061.2"
],
"AlphaFoldDB": [
"P07205"
],
"SMR": [
"P07205"
],
"BioGRID": [
"111253"
],
"IntAct": [
"P07205"
],
"MINT": [
"P07205"
],
"STRING": [
"9606.ENSP00000305995"
],
"BindingDB": [
"P07205"
],
"ChEMBL": [
"CHEMBL2096677"
],
"DrugBank": [
"DB00787"
],
"GlyGen": [
"P07205"
],
"iPTMnet": [
"P07205"
],
"PhosphoSitePlus": [
"P07205"
],
"SwissPalm": [
"P07205"
],
"BioMuta": [
"PGK2"
],
"DMDM": [
"21264485"
],
"jPOST": [
"P07205"
],
"MassIVE": [
"P07205"
],
"PaxDb": [
"9606-ENSP00000305995"
],
"PeptideAtlas": [
"P07205"
],
"PRIDE": [
"P07205"
],
"ProteomicsDB": [
"51974"
],
"Pumba": [
"P07205"
],
"Antibodypedia": [
"30847"
],
"DNASU": [
"5232"
],
"Ensembl": [
"ENST00000304801.6"
],
"KEGG": [
"hsa:5232"
],
"MANE-Select": [
"ENST00000304801.6"
],
"UCSC": [
"uc003ozu.4"
],
"AGR": [
"HGNC:8898"
],
"CTD": [
"5232"
],
"DisGeNET": [
"5232"
],
"GeneCards": [
"PGK2"
],
"HGNC": [
"HGNC:8898"
],
"HPA": [
"ENSG00000170950"
],
"MIM": [
"172270"
],
"neXtProt": [
"NX_P07205"
],
"OpenTargets": [
"ENSG00000170950"
],
"PharmGKB": [
"PA33237"
],
"VEuPathDB": [
"HostDB:ENSG00000170950"
],
"eggNOG": [
"KOG1367"
],
"GeneTree": [
"ENSGT00390000008820"
],
"HOGENOM": [
"CLU_025427_0_0_1"
],
"InParanoid": [
"P07205"
],
"OMA": [
"DMIFDIG"
],
"OrthoDB": [
"5477183at2759"
],
"PhylomeDB": [
"P07205"
],
"TreeFam": [
"TF300489"
],
"BioCyc": [
"MetaCyc:HS10215-MONOMER"
],
"BRENDA": [
"2.7.2.3"
],
"PathwayCommons": [
"P07205"
],
"Reactome": [
"R-HSA-70171",
"R-HSA-70263"
],
"SignaLink": [
"P07205"
],
"SIGNOR": [
"P07205"
],
"UniPathway": [
"UPA00109"
],
"BioGRID-ORCS": [
"5232"
],
"GenomeRNAi": [
"5232"
],
"Pharos": [
"P07205"
],
"PRO": [
"PR:P07205"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"P07205"
],
"Bgee": [
"ENSG00000170950"
],
"ExpressionAtlas": [
"P07205"
],
"GO": [
"GO:0005829",
"GO:0070062",
"GO:0005634",
"GO:0035686",
"GO:0043531",
"GO:0005524",
"GO:0004618",
"GO:0061621",
"GO:0030317",
"GO:0006094",
"GO:0006096",
"GO:0016310"
],
"CDD": [
"cd00318"
],
"Gene3D": [
"3.40.50.1260"
],
"HAMAP": [
"MF_00145"
],
"InterPro": [
"IPR001576",
"IPR015911",
"IPR015824",
"IPR036043"
],
"PANTHER": [
"PTHR11406",
"PTHR11406:SF10"
],
"Pfam": [
"PF00162"
],
"PIRSF": [
"PIRSF000724"
],
"PRINTS": [
"PR00477"
],
"SUPFAM": [
"SSF53748"
],
"PROSITE": [
"PS00111"
]
},
"citations": [
{
"title": "Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.",
"pubmedID": "3453121",
"doi": "10.1038/326501a0"
},
{
"title": "Complete sequencing and characterization of 21,243 full-length human cDNAs.",
"pubmedID": "14702039",
"doi": "10.1038/ng1285"
},
{
"title": "The DNA sequence and analysis of human chromosome 6.",
"pubmedID": "14574404",
"doi": "10.1038/nature02055"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
},
{
"title": "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.",
"pubmedID": "19690332",
"doi": "10.1126/scisignal.2000007"
},
{
"title": "Initial characterization of the human central proteome.",
"pubmedID": "21269460",
"doi": "10.1186/1752-0509-5-17"
},
{
"title": "Characteristics of testis-specific phosphoglycerate kinase 2 and its association with human sperm quality.",
"pubmedID": "26677959",
"doi": "10.1093/humrep/dev301"
}
],
"sequence": {
"length": 417,
"mass": 44796,
"checksum": "0CD5C71C2D3A9272",
"modified": {
"$date": {
"$numberLong": "1169510400000"
}
},
"version": 3,
"sequence": "MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVLMSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLENLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGKATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIVKATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM"
},
"existence": 0,
"relevance": 1,
"proteinID": 719043473
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}