Details Currently Unavailable

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AI-Generated Summary

Array

Raw Database JSON for Gene ID: 57821

{
    "geneID": 57821,
    "tax": {
        "id": 9606,
        "name": [
            {
                "name": "Homo sapiens Linnaeus 1758"
            },
            {
                "name": "Homo sapiens",
                "type": 0
            },
            {
                "name": "human",
                "type": 4
            }
        ]
    },
    "accession": {
        "gene": [
            "AL021068.2"
        ]
    },
    "genePos": {
        "start": 169394870,
        "end": 169460669
    },
    "orientation": true,
    "symbol": "CCDC181",
    "created": {
        "$date": {
            "$numberLong": "1738333350260"
        }
    },
    "crossReference": {
        "enseGeneID": "ENSG00000117477",
        "enseRnaID": [
            "ENST00000545005.5"
        ],
        "enseProtID": [
            "ENSP00000442297.1"
        ]
    },
    "chrom": {
        "pos": "1",
        "type": 1,
        "loc": "1q24.2"
    },
    "desc": "coiled-coil domain containing 181",
    "geneType": 5,
    "ontology": [
        {
            "id": "GO:0008017",
            "term": "microtubule binding",
            "cat": 0
        },
        {
            "id": "GO:0002177",
            "term": "manchette",
            "cat": 2
        },
        {
            "id": "GO:0005737",
            "term": "cytoplasm",
            "cat": 2
        },
        {
            "id": "GO:0005874",
            "term": "microtubule",
            "cat": 2
        },
        {
            "id": "GO:0036126",
            "term": "sperm flagellum",
            "cat": 2
        }
    ],
    "geneRelations": [
        {
            "type": 8,
            "similarGenes": [
                "103568124"
            ]
        }
    ],
    "protein": [
        {
            "symbol": "CC181_HUMAN",
            "accession": [
                "Q5TID7",
                "O60780",
                "Q53FD5",
                "Q5TID9",
                "Q8TC48"
            ],
            "databaseIDs": {
                "NCBI Taxonomy": [
                    "9606"
                ],
                "EMBL": [
                    "AL049687",
                    "AK223354",
                    "AL021068",
                    "BC026073"
                ],
                "CCDS": [
                    "CCDS1279.1",
                    "CCDS72979.1"
                ],
                "RefSeq": [
                    "NP_001287897.1",
                    "NP_001287898.1",
                    "NP_067002.1",
                    "XP_005245440.1",
                    "XP_011508129.1",
                    "XP_016857427.1",
                    "XP_016857428.1",
                    "XP_016857429.1"
                ],
                "AlphaFoldDB": [
                    "Q5TID7"
                ],
                "SMR": [
                    "Q5TID7"
                ],
                "BioGRID": [
                    "121780"
                ],
                "IntAct": [
                    "Q5TID7"
                ],
                "MINT": [
                    "Q5TID7"
                ],
                "STRING": [
                    "9606.ENSP00000356780"
                ],
                "GlyGen": [
                    "Q5TID7"
                ],
                "iPTMnet": [
                    "Q5TID7"
                ],
                "PhosphoSitePlus": [
                    "Q5TID7"
                ],
                "BioMuta": [
                    "CCDC181"
                ],
                "DMDM": [
                    "74746645"
                ],
                "jPOST": [
                    "Q5TID7"
                ],
                "MassIVE": [
                    "Q5TID7"
                ],
                "PaxDb": [
                    "9606-ENSP00000356780"
                ],
                "PeptideAtlas": [
                    "Q5TID7"
                ],
                "ProteomicsDB": [
                    "65189",
                    "65190",
                    "65191"
                ],
                "Antibodypedia": [
                    "34357"
                ],
                "DNASU": [
                    "57821"
                ],
                "Ensembl": [
                    "ENST00000367805.7",
                    "ENST00000367806.8",
                    "ENST00000545005.5"
                ],
                "KEGG": [
                    "hsa:57821"
                ],
                "MANE-Select": [
                    "ENST00000367806.8"
                ],
                "UCSC": [
                    "uc001gfz.2"
                ],
                "AGR": [
                    "HGNC:28051"
                ],
                "CTD": [
                    "57821"
                ],
                "DisGeNET": [
                    "57821"
                ],
                "GeneCards": [
                    "CCDC181"
                ],
                "HGNC": [
                    "HGNC:28051"
                ],
                "HPA": [
                    "ENSG00000117477"
                ],
                "neXtProt": [
                    "NX_Q5TID7"
                ],
                "OpenTargets": [
                    "ENSG00000117477"
                ],
                "PharmGKB": [
                    "PA142672498"
                ],
                "VEuPathDB": [
                    "HostDB:ENSG00000117477"
                ],
                "eggNOG": [
                    "ENOG502QV5R"
                ],
                "GeneTree": [
                    "ENSGT00390000018244"
                ],
                "HOGENOM": [
                    "CLU_040811_0_0_1"
                ],
                "InParanoid": [
                    "Q5TID7"
                ],
                "OMA": [
                    "KAWLMRK"
                ],
                "OrthoDB": [
                    "2964940at2759"
                ],
                "PhylomeDB": [
                    "Q5TID7"
                ],
                "TreeFam": [
                    "TF331115"
                ],
                "PathwayCommons": [
                    "Q5TID7"
                ],
                "SignaLink": [
                    "Q5TID7"
                ],
                "BioGRID-ORCS": [
                    "57821"
                ],
                "ChiTaRS": [
                    "CCDC181"
                ],
                "GenomeRNAi": [
                    "57821"
                ],
                "Pharos": [
                    "Q5TID7"
                ],
                "PRO": [
                    "PR:Q5TID7"
                ],
                "Proteomes": [
                    "UP000005640"
                ],
                "RNAct": [
                    "Q5TID7"
                ],
                "Bgee": [
                    "ENSG00000117477"
                ],
                "ExpressionAtlas": [
                    "Q5TID7"
                ],
                "GO": [
                    "GO:0005737",
                    "GO:0002177",
                    "GO:0005874",
                    "GO:0036126",
                    "GO:0008017"
                ],
                "InterPro": [
                    "IPR026687"
                ],
                "PANTHER": [
                    "PTHR14320",
                    "PTHR14320:SF2"
                ]
            },
            "citations": [
                {
                    "title": "The DNA sequence and biological annotation of human chromosome 1.",
                    "pubmedID": "16710414",
                    "doi": "10.1038/nature04727"
                },
                {
                    "title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
                    "pubmedID": "15489334",
                    "doi": "10.1101/gr.2596504"
                }
            ],
            "sequence": {
                "length": 509,
                "mass": 60103,
                "checksum": "F3FE11900539F24E",
                "modified": {
                    "$date": {
                        "$numberLong": "1103587200000"
                    }
                },
                "version": 1,
                "sequence": "MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTFKNYFENERNMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRQENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFRFTDHYN"
            },
            "existence": 0,
            "relevance": 1,
            "proteinID": 555724
        },
        {
            "symbol": "B2R917_HUMAN",
            "accession": [
                "B2R917"
            ],
            "databaseIDs": {
                "NCBI Taxonomy": [
                    "9606"
                ],
                "EMBL": [
                    "AK313598",
                    "BAG36364.1"
                ],
                "RefSeq": [
                    "NP_001287897.1"
                ],
                "AlphaFoldDB": [
                    "B2R917"
                ],
                "PeptideAtlas": [
                    "B2R917"
                ],
                "DNASU": [
                    "57821"
                ],
                "CTD": [
                    "57821"
                ],
                "DisGeNET": [
                    "57821"
                ],
                "OrthoDB": [
                    "2964940at2759"
                ],
                "BioGRID-ORCS": [
                    "57821"
                ],
                "GO": [
                    "GO:0005737",
                    "GO:0005856",
                    "GO:0031514",
                    "GO:0008017"
                ],
                "InterPro": [
                    "IPR026687"
                ],
                "PANTHER": [
                    "PTHR14320",
                    "PTHR14320:SF2"
                ],
                "ARBA": [
                    "ARBA00002213",
                    "ARBA00004230",
                    "ARBA00004245",
                    "ARBA00005737",
                    "ARBA00022306",
                    "ARBA00022490",
                    "ARBA00023054",
                    "ARBA00023212",
                    "ARBA00023273"
                ],
                "SAM": [
                    "MobiDB-lite"
                ]
            },
            "sequence": {
                "length": 508,
                "mass": 59915,
                "checksum": "5DEBB60ED87BAC1E",
                "modified": {
                    "$date": {
                        "$numberLong": "1214870400000"
                    }
                },
                "version": 1,
                "sequence": "MNENKDTDSKKSEEYEDDFEKDLEWLINENEKSDASIIEMACEKEENINQDLKENETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGIQPLDPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQEPVNDKRERKLKFKDQLVDLEVPPLEDTTTSKNYFENERNMFGKLSQLCISNDFGQEDVLLSLTNGSCEENKDRTILVERDGKFELLNLQDIASQGFLPPINNANSTENDPQQLLPRSSNSSVSGTKKEDSTAKIHAVTHSSTGEPLAYIAQPPLNRKTCPSSAVNSDRSKGNGKSNHRTQSAHISPVTSTYCLSPRQKELQKQLEEKREKLKREEERRKIEEEKEKKRENDIVFKAWLQKKREQVLEMRRIQRAKEIEDMNSRENRDPQQAFRLWLKKKHEEQMKERQTEELRKQEECLFFLKGTEGRERAFKQWLRRKRMEKMAEQQAVRERTRQLRLEAKRSKQLQHHLYMSEAKPFRFTDHYN"
            },
            "existence": 1,
            "relevance": 2,
            "proteinID": 3390952702
        }
    ],
    "mRNAExpressions": {
        "proteinAtlas": [
            {
                "l": "Granulocytes",
                "c": "basophil",
                "e": 1
            }
        ]
    },
    "singleCellExpressions": {
        "cellSignificanceIndex": [
            {
                "cell_id": "CL0000067",
                "cell_term": "ciliated epithelial cell",
                "context": "overall",
                "pVal": 0.4388790266050768,
                "deltaVal": 1,
                "csiScore": 12.899758958701591,
                "rCsiScore": 11.343746237602105,
                "prsScore": 92.0276
            },
            {
                "cell_id": "CL1000271",
                "cell_term": "lung ciliated cell",
                "context": "overall",
                "pVal": 0.5610772487048612,
                "deltaVal": 1,
                "csiScore": 5.970408107961627,
                "rCsiScore": 6.903782603545771,
                "prsScore": 93.8521
            },
            {
                "cell_id": "CL0000750",
                "cell_term": "OFF-bipolar cell",
                "context": "overall",
                "pVal": 0.6191411359018746,
                "deltaVal": 1,
                "csiScore": 4.824714042346072,
                "rCsiScore": 6.596897838303254,
                "prsScore": 95.2883
            },
            {
                "cell_id": "CL0011012",
                "cell_term": "neural crest cell",
                "context": "overall",
                "pVal": 0.6797413501572225,
                "deltaVal": 1,
                "csiScore": 4.124836751939771,
                "rCsiScore": 3.2602781981001696,
                "prsScore": 94.3704
            },
            {
                "cell_id": "CL0005012",
                "cell_term": "multi-ciliated epithelial cell",
                "context": "overall",
                "pVal": 0.6546271637523418,
                "deltaVal": 1,
                "csiScore": 3.7539724732707187,
                "rCsiScore": 3.7464636121236126,
                "prsScore": 93.7013
            },
            {
                "cell_id": "CL0000706",
                "cell_term": "choroid plexus epithelial cell",
                "context": "overall",
                "pVal": 0.6956279328181929,
                "deltaVal": 1,
                "csiScore": 2.87075155576831,
                "rCsiScore": 4.7011972492077465,
                "prsScore": 93.7168
            },
            {
                "cell_id": "CL4023051",
                "cell_term": "vascular leptomeningeal cell",
                "context": "overall",
                "pVal": 0.6943204055242898,
                "deltaVal": 1,
                "csiScore": 2.7777809641249176,
                "rCsiScore": 4.869705808716846,
                "prsScore": 95.2908
            },
            {
                "cell_id": "CL4023018",
                "cell_term": "pvalb GABAergic cortical interneuron",
                "context": "overall",
                "pVal": 0.672564853454366,
                "deltaVal": 1,
                "csiScore": 2.735035275292749,
                "rCsiScore": 3.4025862937410527,
                "prsScore": 89.575
            },
            {
                "cell_id": "CL0000338",
                "cell_term": "neuroblast (sensu Nematoda and Protostomia)",
                "context": "overall",
                "pVal": 0.6844924995908843,
                "deltaVal": 1,
                "csiScore": 2.68309313497598,
                "rCsiScore": 3.098560125798845,
                "prsScore": 92.6455
            },
            {
                "cell_id": "CL0000064",
                "cell_term": "ciliated cell",
                "context": "overall",
                "pVal": 0.6720688785356272,
                "deltaVal": 1,
                "csiScore": 2.6160068409253743,
                "rCsiScore": 4.238410199264292,
                "prsScore": 92.7465
            },
            {
                "cell_id": "CL0002586",
                "cell_term": "retinal pigment epithelial cell",
                "context": "overall",
                "pVal": 0.676986798813143,
                "deltaVal": 1,
                "csiScore": 2.5899808324853884,
                "rCsiScore": 5.142829218600079,
                "prsScore": 94.9532
            },
            {
                "cell_id": "CL0000681",
                "cell_term": "radial glial cell",
                "context": "overall",
                "pVal": 0.6790705591893764,
                "deltaVal": 1,
                "csiScore": 2.5864499424626013,
                "rCsiScore": 3.593217629367625,
                "prsScore": 96.2785
            },
            {
                "cell_id": "CL0000030",
                "cell_term": "glioblast",
                "context": "overall",
                "pVal": 0.6591606306505571,
                "deltaVal": 1,
                "csiScore": 2.5700895646740265,
                "rCsiScore": 4.099894005495765,
                "prsScore": 92.7577
            },
            {
                "cell_id": "CL0000751",
                "cell_term": "rod bipolar cell",
                "context": "overall",
                "pVal": 0.7089574469249489,
                "deltaVal": 1,
                "csiScore": 2.558917010005886,
                "rCsiScore": 4.598206872773002,
                "prsScore": 94.1211
            },
            {
                "cell_id": "CL0000604",
                "cell_term": "retinal rod cell",
                "context": "overall",
                "pVal": 0.6927124083350482,
                "deltaVal": 1,
                "csiScore": 2.513130898645876,
                "rCsiScore": 4.429433365939035,
                "prsScore": 94.2802
            },
            {
                "cell_id": "CL2000032",
                "cell_term": "peripheral nervous system neuron",
                "context": "overall",
                "pVal": 0.6728620199055033,
                "deltaVal": 1,
                "csiScore": 2.4320926313970324,
                "rCsiScore": 3.3138808940861484,
                "prsScore": 93.7074
            },
            {
                "cell_id": "CL0013000",
                "cell_term": "forebrain radial glial cell",
                "context": "overall",
                "pVal": 0.602197001345897,
                "deltaVal": 1,
                "csiScore": 2.394605230794458,
                "rCsiScore": 7.683370191810228,
                "prsScore": 96.7282
            },
            {
                "cell_id": "CL0000065",
                "cell_term": "ependymal cell",
                "context": "overall",
                "pVal": 0.697206413318624,
                "deltaVal": 1,
                "csiScore": 2.3607087750734164,
                "rCsiScore": 4.790237123251976,
                "prsScore": 86.204
            },
            {
                "cell_id": "CL0000748",
                "cell_term": "retinal bipolar neuron",
                "context": "overall",
                "pVal": 0.7089285920453552,
                "deltaVal": 1,
                "csiScore": 2.327330139955578,
                "rCsiScore": 4.358782367605181,
                "prsScore": 92.5429
            },
            {
                "cell_id": "CL4023016",
                "cell_term": "VIP GABAergic cortical interneuron",
                "context": "overall",
                "pVal": 0.7043214767289414,
                "deltaVal": 1,
                "csiScore": 2.2934372770814226,
                "rCsiScore": 2.7394900802961337,
                "prsScore": 91.0434
            },
            {
                "cell_id": "CL0000573",
                "cell_term": "retinal cone cell",
                "context": "overall",
                "pVal": 0.6656468914811022,
                "deltaVal": 1,
                "csiScore": 2.246811260858821,
                "rCsiScore": 3.616351816406155,
                "prsScore": 92.3077
            },
            {
                "cell_id": "CL4023017",
                "cell_term": "sst GABAergic cortical interneuron",
                "context": "overall",
                "pVal": 0.7012178869244274,
                "deltaVal": 1,
                "csiScore": 2.1686678909450485,
                "rCsiScore": 2.795735738141979,
                "prsScore": 91.6743
            },
            {
                "cell_id": "CL0002145",
                "cell_term": "ciliated columnar cell of tracheobronchial tree",
                "context": "overall",
                "pVal": 0.5905568063260191,
                "deltaVal": 1,
                "csiScore": 2.124346455264083,
                "rCsiScore": 4.842469160314659,
                "prsScore": 92.2141
            },
            {
                "cell_id": "CL4023064",
                "cell_term": "caudal ganglionic eminence derived cortical interneuron",
                "context": "overall",
                "pVal": 0.6770715948326682,
                "deltaVal": 1,
                "csiScore": 2.0723325250075786,
                "rCsiScore": 3.659863490364026,
                "prsScore": 90.7949
            },
            {
                "cell_id": "CL4033044",
                "cell_term": "deuterosomal cell",
                "context": "overall",
                "pVal": 0.6206165603402192,
                "deltaVal": 1,
                "csiScore": 1.91588056063376,
                "rCsiScore": 6.4771566074430575,
                "prsScore": 92.6508
            },
            {
                "cell_id": "CL4023011",
                "cell_term": "lamp5 GABAergic cortical interneuron",
                "context": "overall",
                "pVal": 0.7057049638998858,
                "deltaVal": 1,
                "csiScore": 1.5705069449340758,
                "rCsiScore": 2.6361665313542213,
                "prsScore": 91.1521
            },
            {
                "cell_id": "CL0000287",
                "cell_term": "eye photoreceptor cell",
                "context": "overall",
                "pVal": 0.6311543280891698,
                "deltaVal": 1,
                "csiScore": 1.2040079702097082,
                "rCsiScore": 13.544813140778306,
                "prsScore": 96.5975
            },
            {
                "cell_id": "CL0000700",
                "cell_term": "dopaminergic neuron",
                "context": "overall",
                "pVal": 0.6880355304562165,
                "deltaVal": 1,
                "csiScore": 1.0564290778662886,
                "rCsiScore": 5.969895980513581,
                "prsScore": 90.7096
            },
            {
                "cell_id": "CL4023040",
                "cell_term": "L2/3-6 intratelencephalic projecting glutamatergic neuron",
                "context": "overall",
                "pVal": 0.7054329754214037,
                "deltaVal": 1,
                "csiScore": 1.0237710275551275,
                "rCsiScore": 2.4881389790603934,
                "prsScore": 89.4535
            },
            {
                "cell_id": "CL4023036",
                "cell_term": "chandelier pvalb GABAergic cortical interneuron",
                "context": "overall",
                "pVal": 0.7117872704680672,
                "deltaVal": 1,
                "csiScore": 0.8266477592804833,
                "rCsiScore": 2.5853458792423853,
                "prsScore": 92.6663
            },
            {
                "cell_id": "CL4023041",
                "cell_term": "L5 extratelencephalic projecting glutamatergic cortical neuron",
                "context": "overall",
                "pVal": 0.7245512402266456,
                "deltaVal": 1,
                "csiScore": 0.6285099305351727,
                "rCsiScore": 2.2617183167849144,
                "prsScore": 89.6812
            }
        ]
    }
}