Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 6757
{
"geneID": 6757,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC244505.1"
]
},
"genePos": {
"start": 52696896,
"end": 52707227
},
"orientation": true,
"symbol": "SSX2",
"created": {
"$date": {
"$numberLong": "1738333349190"
}
},
"crossReference": {
"enseGeneID": "ENSG00000241476",
"enseRnaID": [
"ENST00000336777.9"
],
"enseProtID": [
"ENSP00000338796.5"
]
},
"chrom": {
"loc": "Xp11.22"
},
"desc": "SSX family member 2",
"geneType": 5,
"mim": [
{
"id": 300192,
"relation": 0
},
{
"id": 300813,
"relation": 1,
"cui": 39101
}
],
"ontology": [
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
12007189,
25416956,
28514442,
32296183,
32814053
],
"cat": 0
},
{
"id": "GO:0006355",
"term": "regulation of DNA-templated transcription",
"pubMed": [
7539744
],
"cat": 1
},
{
"id": "GO:0005634",
"term": "nucleus",
"cat": 2
}
],
"geneRelations": [
{
"type": 8,
"similarGenes": [
"326337"
]
}
],
"protein": [
{
"symbol": "SSX2_HUMAN",
"name": "Protein SSX2",
"accession": [
"Q16385",
"Q16404",
"Q5JS26",
"Q96IP7",
"Q9BU88"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"X86175",
"AL445236",
"AL450023",
"AL445236",
"AL450023",
"BC002818",
"BC007343",
"BC016957",
"BC069313",
"BC071827",
"BC103863",
"S79332",
"X79200",
"S79894"
],
"CCDS": [
"CCDS14344.2",
"CCDS14345.2",
"CCDS48129.1",
"CCDS65267.1"
],
"PIR": [
"S55058"
],
"RefSeq": [
"NP_001157889.1",
"NP_001265626.1",
"NP_001265630.1",
"NP_001265631.1",
"NP_003138.3",
"NP_783629.1"
],
"PDB": [
"8HQY"
],
"PDBsum": [
"8HQY"
],
"AlphaFoldDB": [
"Q16385"
],
"EMDB": [
"EMD-34954"
],
"SMR": [
"Q16385"
],
"BioGRID": [
"112635",
"608281"
],
"IntAct": [
"Q16385"
],
"BindingDB": [
"Q16385"
],
"iPTMnet": [
"Q16385"
],
"PhosphoSitePlus": [
"Q16385"
],
"BioMuta": [
"SSX2"
],
"DMDM": [
"3915028"
],
"MassIVE": [
"Q16385"
],
"PeptideAtlas": [
"Q16385"
],
"ProteomicsDB": [
"60867",
"60868"
],
"Pumba": [
"Q16385"
],
"Antibodypedia": [
"43485",
"73920"
],
"DNASU": [
"6757"
],
"Ensembl": [
"ENST00000336777.9",
"ENST00000337502.6",
"ENST00000596480.6",
"ENST00000612490.1",
"ENST00000616191.4"
],
"KEGG": [
"hsa:6757",
"hsa:727837"
],
"MANE-Select": [
"ENST00000337502.6",
"ENST00000596480.6"
],
"UCSC": [
"uc004dqy.3"
],
"AGR": [
"HGNC:11336",
"HGNC:22263"
],
"CTD": [
"6757",
"727837"
],
"DisGeNET": [
"6757",
"727837"
],
"GeneCards": [
"SSX2",
"SSX2B"
],
"HGNC": [
"HGNC:11336",
"HGNC:22263"
],
"HPA": [
"ENSG00000241476",
"ENSG00000268447"
],
"MalaCards": [
"SSX2"
],
"MIM": [
"300192"
],
"neXtProt": [
"NX_Q16385"
],
"OpenTargets": [
"ENSG00000241476"
],
"Orphanet": [
"3273"
],
"PharmGKB": [
"PA162404839"
],
"VEuPathDB": [
"HostDB:ENSG00000241476",
"HostDB:ENSG00000268447"
],
"GeneTree": [
"ENSGT00390000012484"
],
"HOGENOM": [
"CLU_097196_0_0_1"
],
"InParanoid": [
"Q16385"
],
"OMA": [
"KAWEYSH"
],
"OrthoDB": [
"4679389at2759"
],
"PhylomeDB": [
"Q16385"
],
"TreeFam": [
"TF338517"
],
"PathwayCommons": [
"Q16385"
],
"SignaLink": [
"Q16385"
],
"BioGRID-ORCS": [
"6757",
"727837"
],
"ChiTaRS": [
"SSX2",
"SSX2B"
],
"GeneWiki": [
"SSX2"
],
"Pharos": [
"Q16385"
],
"PRO": [
"PR:Q16385"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"Q16385"
],
"Bgee": [
"ENSG00000241476"
],
"GO": [
"GO:0005634",
"GO:0006355"
],
"InterPro": [
"IPR003655",
"IPR001909",
"IPR036051",
"IPR019041"
],
"PANTHER": [
"PTHR14112:SF24",
"PTHR14112"
],
"Pfam": [
"PF01352",
"PF09514"
],
"SMART": [
"SM00349"
],
"SUPFAM": [
"SSF109640"
],
"PROSITE": [
"PS50806"
]
},
"citations": [
{
"title": "Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.",
"pubmedID": "7539744",
"doi": "10.1002/j.1460-2075.1995.tb07228.x"
},
{
"title": "The DNA sequence of the human X chromosome.",
"pubmedID": "15772651",
"doi": "10.1038/nature03440"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
},
{
"title": "Identification of two alternative fusion genes, SYT-SSX1 and SYT-SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas.",
"pubmedID": "7655467",
"doi": "10.1093/hmg/4.6.1097"
},
{
"title": "Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma.",
"pubmedID": "7951320",
"doi": "10.1038/ng0894-502"
},
{
"title": "Molecular diagnosis of synovial sarcoma and characterization of a variant SYT-SSX2 fusion transcript.",
"pubmedID": "7495284"
},
{
"title": "The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.",
"pubmedID": "12007189",
"doi": "10.1002/gcc.10073"
},
{
"title": "Toward a comprehensive characterization of a human cancer cell phosphoproteome.",
"pubmedID": "23186163",
"doi": "10.1021/pr300630k"
}
],
"sequence": {
"length": 188,
"mass": 21620,
"checksum": "BF5D18AA5F45B1B1",
"modified": {
"$date": {
"$numberLong": "913680000000"
}
},
"version": 2,
"sequence": "MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE"
},
"existence": 0,
"relevance": 1,
"proteinID": 705995035
},
{
"symbol": "R9QTR3_HUMAN",
"accession": [
"R9QTR3"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"JX014236",
"AGC59876.1"
],
"RefSeq": [
"NP_001265626.1",
"NP_001265631.1"
],
"AlphaFoldDB": [
"R9QTR3"
],
"PeptideAtlas": [
"R9QTR3"
],
"DNASU": [
"6757"
],
"CTD": [
"6757",
"727837"
],
"DisGeNET": [
"6757",
"727837"
],
"OrthoDB": [
"4679389at2759"
],
"BioGRID-ORCS": [
"6757",
"727837"
],
"GO": [
"GO:0005634",
"GO:0006355"
],
"InterPro": [
"IPR003655",
"IPR001909",
"IPR036051",
"IPR019041"
],
"PANTHER": [
"PTHR14112:SF24",
"PTHR14112"
],
"Pfam": [
"PF09514"
],
"SMART": [
"SM00349"
],
"SUPFAM": [
"SSF109640"
],
"PROSITE": [
"PS50806",
"PS50806"
],
"SAM": [
"MobiDB-lite"
]
},
"sequence": {
"length": 214,
"mass": 24695,
"checksum": "B4E6E903C03B92A8",
"modified": {
"$date": {
"$numberLong": "1379462400000"
}
},
"version": 1,
"sequence": "MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVYMKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMTFGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEKIHERSGNREAQEKEERRGTAHRWSSQNTHNIGPKRGEHAWTHRLRERKQLVIYEEISDPEEDDE"
},
"existence": 1,
"relevance": 2,
"proteinID": 2893855820
}
]
}