Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 7484
{
"geneID": 7484,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC015855.13"
]
},
"genePos": {
"start": 46833189,
"end": 46886738
},
"orientation": true,
"symbol": "WNT9B",
"created": {
"$date": {
"$numberLong": "1738333349247"
}
},
"crossReference": {
"enseGeneID": "ENSG00000158955",
"enseRnaID": [
"ENST00000393461.2"
],
"enseProtID": [
"ENSP00000377105.2"
]
},
"chrom": {
"pos": "17",
"type": 1,
"loc": "17q21.32"
},
"desc": "Wnt family member 9B",
"geneType": 5,
"mim": [
{
"id": 602864,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-1266738",
"term": "Developmental Biology",
"cat": 10
},
{
"id": "R-HSA-162582",
"term": "Signal Transduction",
"cat": 10
},
{
"id": "R-HSA-195721",
"term": "Signaling by WNT",
"cat": 11
},
{
"id": "R-HSA-372790",
"term": "Signaling by GPCR",
"cat": 11
},
{
"id": "R-HSA-9830369",
"term": "Kidney development",
"cat": 11
},
{
"id": "R-HSA-3238698",
"term": "WNT ligand biogenesis and trafficking",
"cat": 12
},
{
"id": "R-HSA-500792",
"term": "GPCR ligand binding",
"cat": 12
},
{
"id": "R-HSA-9831926",
"term": "Nephron development",
"cat": 12
},
{
"id": "R-HSA-373080",
"term": "Class B/2 (Secretin family receptors)",
"cat": 13
},
{
"id": "GO:0005109",
"term": "frizzled binding",
"cat": 0
},
{
"id": "GO:0005125",
"term": "cytokine activity",
"cat": 0
},
{
"id": "GO:0039706",
"term": "co-receptor binding",
"cat": 0
},
{
"id": "GO:0048018",
"term": "receptor ligand activity",
"pubMed": [
28733458
],
"cat": 0
},
{
"id": "GO:0001658",
"term": "branching involved in ureteric bud morphogenesis",
"cat": 1
},
{
"id": "GO:0001701",
"term": "in utero embryonic development",
"cat": 1
},
{
"id": "GO:0003339",
"term": "regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis",
"cat": 1
},
{
"id": "GO:0009267",
"term": "cellular response to starvation",
"cat": 1
},
{
"id": "GO:0009786",
"term": "regulation of asymmetric cell division",
"cat": 1
},
{
"id": "GO:0030182",
"term": "neuron differentiation",
"cat": 1
},
{
"id": "GO:0030539",
"term": "male genitalia development",
"cat": 1
},
{
"id": "GO:0032526",
"term": "response to retinoic acid",
"pubMed": [
11604992
],
"cat": 1
},
{
"id": "GO:0035150",
"term": "regulation of tube size",
"cat": 1
},
{
"id": "GO:0035567",
"term": "non-canonical Wnt signaling pathway",
"pubMed": [
25640183
],
"cat": 1
},
{
"id": "GO:0045165",
"term": "cell fate commitment",
"cat": 1
},
{
"id": "GO:0048701",
"term": "embryonic cranial skeleton morphogenesis",
"cat": 1
},
{
"id": "GO:0060021",
"term": "roof of mouth development",
"cat": 1
},
{
"id": "GO:0060070",
"term": "canonical Wnt signaling pathway",
"cat": 1
},
{
"id": "GO:0060070",
"term": "canonical Wnt signaling pathway",
"pubMed": [
28733458
],
"cat": 1
},
{
"id": "GO:0060071",
"term": "Wnt signaling pathway, planar cell polarity pathway",
"cat": 1
},
{
"id": "GO:0061038",
"term": "uterus morphogenesis",
"cat": 1
},
{
"id": "GO:0061303",
"term": "cornea development in camera-type eye",
"pubMed": [
16258938
],
"cat": 1
},
{
"id": "GO:0071300",
"term": "cellular response to retinoic acid",
"cat": 1
},
{
"id": "GO:0072003",
"term": "kidney rudiment formation",
"cat": 1
},
{
"id": "GO:0072038",
"term": "mesenchymal stem cell maintenance involved in nephron morphogenesis",
"cat": 1
},
{
"id": "GO:0072044",
"term": "collecting duct development",
"cat": 1
},
{
"id": "GO:0072046",
"term": "establishment of planar polarity involved in nephron morphogenesis",
"cat": 1
},
{
"id": "GO:0072174",
"term": "metanephric tubule formation",
"cat": 1
},
{
"id": "GO:0072181",
"term": "mesonephric duct formation",
"cat": 1
},
{
"id": "GO:1902455",
"term": "negative regulation of stem cell population maintenance",
"pubMed": [
25640183
],
"cat": 1
},
{
"id": "GO:1904948",
"term": "midbrain dopaminergic neuron differentiation",
"pubMed": [
25640183
],
"cat": 1
},
{
"id": "GO:0005576",
"term": "extracellular region",
"cat": 2
},
{
"id": "GO:0005615",
"term": "extracellular space",
"cat": 2
}
],
"protein": [
{
"symbol": "WNT9B_HUMAN",
"name": "Protein Wnt-9b",
"accession": [
"O14905",
"Q6UXT4",
"Q96Q09"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AB063483",
"AY358217",
"AC015855",
"AF028703"
],
"CCDS": [
"CCDS11506.1"
],
"RefSeq": [
"NP_003387.1"
],
"AlphaFoldDB": [
"O14905"
],
"SMR": [
"O14905"
],
"BioGRID": [
"113321"
],
"IntAct": [
"O14905"
],
"STRING": [
"9606.ENSP00000290015"
],
"GlyCosmos": [
"O14905"
],
"GlyGen": [
"O14905"
],
"iPTMnet": [
"O14905"
],
"PhosphoSitePlus": [
"O14905"
],
"BioMuta": [
"WNT9B"
],
"MassIVE": [
"O14905"
],
"PaxDb": [
"9606-ENSP00000290015"
],
"PeptideAtlas": [
"O14905"
],
"Antibodypedia": [
"17705"
],
"DNASU": [
"7484"
],
"Ensembl": [
"ENST00000290015.7",
"ENST00000613753.2"
],
"KEGG": [
"hsa:7484"
],
"MANE-Select": [
"ENST00000290015.7"
],
"UCSC": [
"uc002ikw.2"
],
"AGR": [
"HGNC:12779"
],
"CTD": [
"7484"
],
"DisGeNET": [
"7484"
],
"GeneCards": [
"WNT9B"
],
"HGNC": [
"HGNC:12779"
],
"HPA": [
"ENSG00000158955"
],
"MalaCards": [
"WNT9B"
],
"MIM": [
"602864"
],
"neXtProt": [
"NX_O14905"
],
"OpenTargets": [
"ENSG00000158955"
],
"Orphanet": [
"1848"
],
"PharmGKB": [
"PA37380"
],
"VEuPathDB": [
"HostDB:ENSG00000158955"
],
"eggNOG": [
"KOG3913"
],
"GeneTree": [
"ENSGT00940000158599"
],
"HOGENOM": [
"CLU_033039_2_0_1"
],
"InParanoid": [
"O14905"
],
"OMA": [
"RLELWVP"
],
"OrthoDB": [
"2874082at2759"
],
"PhylomeDB": [
"O14905"
],
"TreeFam": [
"TF105310"
],
"PathwayCommons": [
"O14905"
],
"Reactome": [
"R-HSA-3238698",
"R-HSA-373080",
"R-HSA-9831926"
],
"SignaLink": [
"O14905"
],
"SIGNOR": [
"O14905"
],
"BioGRID-ORCS": [
"7484"
],
"GenomeRNAi": [
"7484"
],
"Pharos": [
"O14905"
],
"PRO": [
"PR:O14905"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"O14905"
],
"Bgee": [
"ENSG00000158955"
],
"ExpressionAtlas": [
"O14905"
],
"GO": [
"GO:0005576",
"GO:0005615",
"GO:0039706",
"GO:0005125",
"GO:0005109",
"GO:0048018",
"GO:0001658",
"GO:0060070",
"GO:0045165",
"GO:0071300",
"GO:0009267",
"GO:0072044",
"GO:0061303",
"GO:0048701",
"GO:0072046",
"GO:0001701",
"GO:0072003",
"GO:0030539",
"GO:0072038",
"GO:0072181",
"GO:0072174",
"GO:1904948",
"GO:1902455",
"GO:0030182",
"GO:0035567",
"GO:0009786",
"GO:0003339",
"GO:0001932",
"GO:0035150",
"GO:0032526",
"GO:0060021",
"GO:0061038",
"GO:0060071"
],
"CDD": [
"cd19354"
],
"Gene3D": [
"3.30.2460.20"
],
"InterPro": [
"IPR005817",
"IPR043158",
"IPR018161"
],
"PANTHER": [
"PTHR12027:SF84",
"PTHR12027"
],
"Pfam": [
"PF00110"
],
"PRINTS": [
"PR01349"
],
"SMART": [
"SM00097"
],
"PROSITE": [
"PS00246"
]
},
"citations": [
{
"title": "Molecular cloning and characterization of WNT14B, a novel member of the WNT gene family.",
"pubmedID": "11604992",
"doi": "10.3892/ijo.19.5.947"
},
{
"title": "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.",
"pubmedID": "12975309",
"doi": "10.1101/gr.1293003"
},
{
"title": "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.",
"pubmedID": "16625196",
"doi": "10.1038/nature04689"
},
{
"title": "Isolation of two novel WNT genes, WNT14 and WNT15, one of which (WNT15) is closely linked to WNT3 on human chromosome 17q21.",
"pubmedID": "9441749",
"doi": "10.1006/geno.1997.5041"
},
{
"title": "Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.",
"pubmedID": "20093360",
"doi": "10.1074/jbc.m109.092130"
},
{
"title": "Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin.",
"pubmedID": "26902720",
"doi": "10.7554/elife.11621"
},
{
"title": "The polycystin complex mediates Wnt/Ca(2+) signalling.",
"pubmedID": "27214281",
"doi": "10.1038/ncb3363"
}
],
"sequence": {
"length": 357,
"mass": 39001,
"checksum": "CC22162F9D294CB8",
"modified": {
"$date": {
"$numberLong": "1291075200000"
}
},
"version": 3,
"sequence": "MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRMGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGTAGRVCSREASCSSLCCGRGYDTQSRLVAFSCHCQVQWCCYVECQQCVQEELVYTCKH"
},
"existence": 0,
"relevance": 1,
"proteinID": 2602242990
},
{
"symbol": "E7EPC3_HUMAN",
"accession": [
"E7EPC3"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AC015855",
"AC019319",
"KC877662"
],
"RefSeq": [
"NP_001307387.1"
],
"IntAct": [
"E7EPC3"
],
"Antibodypedia": [
"17705"
],
"DNASU": [
"7484"
],
"Ensembl": [
"ENST00000393461.2",
"ENST00000633488.1",
"ENSP00000377105.2"
],
"UCSC": [
"uc060glo.1"
],
"CTD": [
"7484"
],
"DisGeNET": [
"7484"
],
"HGNC": [
"HGNC:12779"
],
"VEuPathDB": [
"HostDB:ENSG00000158955"
],
"GeneTree": [
"ENSGT00940000158599"
],
"OrthoDB": [
"2874082at2759"
],
"BioGRID-ORCS": [
"7484"
],
"Proteomes": [
"UP000005640",
"UP000005640"
],
"Bgee": [
"ENSG00000158955"
],
"GO": [
"GO:0005576",
"GO:0005102",
"GO:0016055"
],
"InterPro": [
"IPR005817",
"IPR018161"
],
"PANTHER": [
"PTHR12027:SF84",
"PTHR12027"
],
"Pfam": [
"PF00110"
],
"PRINTS": [
"PR01349"
],
"SMART": [
"SM00097"
],
"PROSITE": [
"PS00246"
],
"ARBA": [
"ARBA00004498",
"ARBA00005683",
"ARBA00022473",
"ARBA00022525",
"ARBA00022530",
"ARBA00022687",
"ARBA00022729",
"ARBA00023288"
],
"RuleBase": [
"RU003500"
],
"SAM": [
"SignalP"
],
"PeptideAtlas": [
"E7EPC3"
],
"ProteomicsDB": [
"E7EPC3"
]
},
"citations": [
{
"title": "Initial sequencing and analysis of the human genome.",
"pubmedID": "11237011",
"doi": "10.1038/35057062"
},
{
"title": "Finishing the euchromatic sequence of the human genome.",
"pubmedID": "15496913",
"doi": "10.1038/nature03001"
},
{
"title": "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.",
"pubmedID": "16625196",
"doi": "10.1038/nature04689"
}
],
"sequence": {
"length": 329,
"mass": 35637,
"checksum": "3280D468FD626662",
"modified": {
"$date": {
"$numberLong": "1299542400000"
}
},
"version": 1,
"sequence": "MRPPPALALAGLCLLALPAAAASYFGLTGREVLTPFPGLGTAAAPAQGGAHLKQCDLLKLSRRQKQLCRREPGLAETLRDAAHLGLLECQFQFRHERWNCSLEGRMGLLKRGFKETAFLYAVSSAALTHTLARACSAGRMERCTCDDSPGLESRQAWQWGVCGDNLKYSTKFLSNFLGSKRGNKDLRARADAHNTHVGIKAVKSGLRTTCKCHGVSGSCAVRTCWKQLSPFRETGQVLKLRYDSAVKVSSATNEALGRLELWAPARQGSLTKGLAPRSGDLVYMEDSPSFCRPSKYSPGTAGWSAVARSQLITTSTSRIQAILPSQLPE"
},
"existence": 0,
"relevance": 2,
"proteinID": 3421683996
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}