Details Currently Unavailable
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AI-Generated Summary
Disclaimer: This summary is AI-generated based on limited data and may be speculative or contain inaccuracies. Detailed expression analysis for this entry is unavailable.
Raw Database JSON for Gene ID: 8689
{
"geneID": 8689,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AC019349.28"
]
},
"genePos": {
"start": 4955,
"end": 8729
},
"orientation": true,
"symbol": "KRT36",
"created": {
"$date": {
"$numberLong": "1738333349594"
}
},
"crossReference": {
"enseGeneID": "ENSG00000126337",
"enseRnaID": [
"ENST00000328119.11"
],
"enseProtID": [
"ENSP00000329165.6"
]
},
"chrom": {
"pos": "17",
"type": 1,
"loc": "17q21.2"
},
"desc": "keratin 36",
"geneType": 5,
"ontology": [
{
"id": "R-HSA-1266738",
"term": "Developmental Biology",
"cat": 10
},
{
"id": "R-HSA-6805567",
"term": "Keratinization",
"cat": 11
},
{
"id": "R-HSA-6809371",
"term": "Formation of the cornified envelope",
"cat": 12
},
{
"id": "GO:0005515",
"term": "protein binding",
"pubMed": [
32296183
],
"cat": 0
},
{
"id": "GO:0030280",
"term": "structural constituent of skin epidermis",
"cat": 0
},
{
"id": "GO:0030280",
"term": "structural constituent of skin epidermis",
"pubMed": [
9756910
],
"cat": 0
},
{
"id": "GO:0008150",
"term": "biological_process",
"cat": 1
},
{
"id": "GO:0030855",
"term": "epithelial cell differentiation",
"cat": 1
},
{
"id": "GO:0045109",
"term": "intermediate filament organization",
"cat": 1
},
{
"id": "GO:0045616",
"term": "regulation of keratinocyte differentiation",
"cat": 1
},
{
"id": "GO:0005829",
"term": "cytosol",
"cat": 2
},
{
"id": "GO:0045095",
"term": "keratin filament",
"pubMed": [
32296183
],
"cat": 2
},
{
"id": "GO:0045111",
"term": "intermediate filament cytoskeleton",
"cat": 2
},
{
"id": "GO:0070062",
"term": "extracellular exosome",
"pubMed": [
23533145
],
"cat": 2
}
],
"protein": [
{
"symbol": "KRT36_HUMAN",
"name": "Keratin, type I cuticular Ha6",
"accession": [
"O76013",
"Q86XG4"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"Y16792",
"CH471152",
"BC043581"
],
"CCDS": [
"CCDS11395.1"
],
"RefSeq": [
"NP_003762.1"
],
"AlphaFoldDB": [
"O76013"
],
"SMR": [
"O76013"
],
"BioGRID": [
"114236"
],
"ComplexPortal": [
"CPX-5663"
],
"IntAct": [
"O76013"
],
"STRING": [
"9606.ENSP00000329165"
],
"CarbonylDB": [
"O76013"
],
"GlyGen": [
"O76013"
],
"iPTMnet": [
"O76013"
],
"PhosphoSitePlus": [
"O76013"
],
"BioMuta": [
"KRT36"
],
"jPOST": [
"O76013"
],
"MassIVE": [
"O76013"
],
"PaxDb": [
"9606-ENSP00000329165"
],
"PeptideAtlas": [
"O76013"
],
"PRIDE": [
"O76013"
],
"ProteomicsDB": [
"50344",
"50345"
],
"Antibodypedia": [
"16678"
],
"DNASU": [
"8689"
],
"Ensembl": [
"ENST00000328119.11",
"ENST00000393986.2"
],
"KEGG": [
"hsa:8689"
],
"MANE-Select": [
"ENST00000328119.11"
],
"UCSC": [
"uc002hwt.3"
],
"AGR": [
"HGNC:6454"
],
"CTD": [
"8689"
],
"DisGeNET": [
"8689"
],
"GeneCards": [
"KRT36"
],
"HGNC": [
"HGNC:6454"
],
"HPA": [
"ENSG00000126337"
],
"MIM": [
"604540"
],
"neXtProt": [
"NX_O76013"
],
"OpenTargets": [
"ENSG00000126337"
],
"PharmGKB": [
"PA30243"
],
"VEuPathDB": [
"HostDB:ENSG00000126337"
],
"eggNOG": [
"ENOG502QQY9"
],
"GeneTree": [
"ENSGT00940000161311"
],
"HOGENOM": [
"CLU_012560_8_0_1"
],
"InParanoid": [
"O76013"
],
"OMA": [
"AVRVPYI"
],
"OrthoDB": [
"4640531at2759"
],
"PhylomeDB": [
"O76013"
],
"TreeFam": [
"TF332742"
],
"PathwayCommons": [
"O76013"
],
"Reactome": [
"R-HSA-6805567",
"R-HSA-6809371"
],
"SignaLink": [
"O76013"
],
"SIGNOR": [
"O76013"
],
"BioGRID-ORCS": [
"8689"
],
"GeneWiki": [
"KRT36"
],
"GenomeRNAi": [
"8689"
],
"Pharos": [
"O76013"
],
"PRO": [
"PR:O76013"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"O76013"
],
"Bgee": [
"ENSG00000126337"
],
"GO": [
"GO:0005829",
"GO:0070062",
"GO:0045111",
"GO:0045095",
"GO:0030280",
"GO:0030855",
"GO:0045109",
"GO:0045616"
],
"Gene3D": [
"1.20.5.170",
"1.20.5.500",
"1.20.5.1160"
],
"InterPro": [
"IPR018039",
"IPR039008",
"IPR002957"
],
"PANTHER": [
"PTHR23239",
"PTHR23239:SF204"
],
"Pfam": [
"PF00038"
],
"PRINTS": [
"PR01248"
],
"SMART": [
"SM01391"
],
"SUPFAM": [
"SSF64593",
"SSF46579"
],
"PROSITE": [
"PS00226",
"PS51842"
]
},
"citations": [
{
"title": "Characterization of a 190-kilobase pair domain of human type I hair keratin genes.",
"pubmedID": "9756910",
"doi": "10.1074/jbc.273.41.26683"
},
{
"title": "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).",
"pubmedID": "15489334",
"doi": "10.1101/gr.2596504"
}
],
"sequence": {
"length": 467,
"mass": 52247,
"checksum": "492B3B2DE3BCAECD",
"modified": {
"$date": {
"$numberLong": "909878400000"
}
},
"version": 1,
"sequence": "MATQTCTPTFSTGSIKGLCGTAGGISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGSCLPGSYLSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPVPCVPSVPCTPAPQVGTQIRTITEEIRDGKVISSREHVQSRPL"
},
"existence": 0,
"relevance": 1,
"proteinID": 556955348
}
],
"singleCellExpressions": {
"cellSignificanceIndex": []
}
}