No CSI details found for gene ID: 2862
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 1426992874
Symbol: MTLR_HUMAN
Name: Motilin receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9441746
Title: Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.
PubMed ID: 9441746
PubMed ID: 10381885
Title: Receptor for motilin identified in the human gastrointestinal system.
PubMed ID: 10381885
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 11322507
Title: Growth hormone secretagogue receptor family members and ligands.
PubMed ID: 11322507
Sequence Information:
- Length: 412
- Mass: 45344
- Checksum: C13FF6165012DEF3
- Sequence:
MGSPWNGSDG PEGAREPPWP ALPPCDERRC SPFPLGALVP VTAVCLCLFV VGVSGNVVTV MLIGRYRDMR TTTNLYLGSM AVSDLLILLG LPFDLYRLWR SRPWVFGPLL CRLSLYVGEG CTYATLLHMT ALSVERYLAI CRPLRARVLV TRRRVRALIA VLWAVALLSA GPFLFLVGVE QDPGISVVPG LNGTARIASS PLASSPPLWL SRAPPPSPPS GPETAEAAAL FSRECRPSPA QLGALRVMLW VTTAYFFLPF LCLSILYGLI GRELWSSRRP LRGPAASGRE RGHRQTVRVL LVVVLAFIIC WLPFHVGRII YINTEDSRMM YFSQYFNIVA LQLFYLSASI NPILYNLISK KYRAAAFKLL LARKSRPRGF HRSRDTAGEV AGDTGGDTVG YTETSANVKT MG
Details Unavailable
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{
"geneID": 2862,
"tax": {
"id": 9606,
"name": [
{
"name": "Homo sapiens Linnaeus 1758"
},
{
"name": "Homo sapiens",
"type": 0
},
{
"name": "human",
"type": 4
}
]
},
"accession": {
"gene": [
"AL137000.6"
]
},
"genePos": {
"start": 5001,
"end": 7040
},
"orientation": true,
"symbol": "MLNR",
"created": {
"$date": {
"$numberLong": "1738333348838"
}
},
"crossReference": {
"enseGeneID": "ENSG00000102539",
"enseRnaID": [
"ENST00000218721.1"
],
"enseProtID": [
"ENSP00000218721.1"
]
},
"chrom": {
"pos": "13",
"type": 1,
"loc": "13q14.2"
},
"desc": "motilin receptor",
"geneType": 5,
"mim": [
{
"id": 602885,
"relation": 0
}
],
"ontology": [
{
"id": "R-HSA-162582",
"term": "Signal Transduction",
"cat": 10
},
{
"id": "R-HSA-372790",
"term": "Signaling by GPCR",
"cat": 11
},
{
"id": "R-HSA-388396",
"term": "GPCR downstream signalling",
"cat": 12
},
{
"id": "R-HSA-500792",
"term": "GPCR ligand binding",
"cat": 12
},
{
"id": "R-HSA-373076",
"term": "Class A\/1 (Rhodopsin-like receptors)",
"cat": 13
},
{
"id": "R-HSA-416476",
"term": "G alpha (q) signalling events",
"cat": 13
},
{
"id": "R-HSA-375276",
"term": "Peptide ligand-binding receptors",
"cat": 14
},
{
"id": "GO:0008528",
"term": "G protein-coupled peptide receptor activity",
"cat": 0
},
{
"id": "GO:0008528",
"term": "G protein-coupled peptide receptor activity",
"pubMed": [
10381885
],
"cat": 0
},
{
"id": "GO:0042562",
"term": "hormone binding",
"pubMed": [
10381885
],
"cat": 0
},
{
"id": "GO:0007186",
"term": "G protein-coupled receptor signaling pathway",
"cat": 1
},
{
"id": "GO:0005829",
"term": "cytosol",
"cat": 2
},
{
"id": "GO:0005886",
"term": "plasma membrane",
"cat": 2
}
],
"protein": [
{
"symbol": "MTLR_HUMAN",
"name": "Motilin receptor",
"accession": [
"O43193"
],
"databaseIDs": {
"NCBI Taxonomy": [
"9606"
],
"EMBL": [
"AF034632",
"AY603964",
"AL137000"
],
"CCDS": [
"CCDS9414.1"
],
"RefSeq": [
"NP_001498.1"
],
"PDB": [
"8IBU",
"8IBV"
],
"PDBsum": [
"8IBU",
"8IBV"
],
"AlphaFoldDB": [
"O43193"
],
"EMDB": [
"EMD-35345",
"EMD-35346"
],
"SMR": [
"O43193"
],
"BioGRID": [
"109120"
],
"IntAct": [
"O43193"
],
"STRING": [
"9606.ENSP00000218721"
],
"BindingDB": [
"O43193"
],
"ChEMBL": [
"CHEMBL2203"
],
"DrugBank": [
"DB00199",
"DB06587"
],
"DrugCentral": [
"O43193"
],
"GuidetoPHARMACOLOGY": [
"297"
],
"GlyCosmos": [
"O43193"
],
"GlyGen": [
"O43193"
],
"iPTMnet": [
"O43193"
],
"PhosphoSitePlus": [
"O43193"
],
"BioMuta": [
"MLNR"
],
"MassIVE": [
"O43193"
],
"PaxDb": [
"9606-ENSP00000218721"
],
"PeptideAtlas": [
"O43193"
],
"ProteomicsDB": [
"48807",
"48808"
],
"Antibodypedia": [
"42284"
],
"DNASU": [
"2862"
],
"Ensembl": [
"ENST00000218721.1"
],
"KEGG": [
"hsa:2862"
],
"MANE-Select": [
"ENST00000218721.1"
],
"UCSC": [
"uc010tgj.2"
],
"AGR": [
"HGNC:4495"
],
"CTD": [
"2862"
],
"DisGeNET": [
"2862"
],
"GeneCards": [
"MLNR"
],
"HGNC": [
"HGNC:4495"
],
"HPA": [
"ENSG00000102539"
],
"MIM": [
"602885"
],
"neXtProt": [
"NX_O43193"
],
"OpenTargets": [
"ENSG00000102539"
],
"PharmGKB": [
"PA28884"
],
"VEuPathDB": [
"HostDB:ENSG00000102539"
],
"eggNOG": [
"KOG3656"
],
"GeneTree": [
"ENSGT01120000271823"
],
"HOGENOM": [
"CLU_009579_6_5_1"
],
"InParanoid": [
"O43193"
],
"OMA": [
"ERRCSPF"
],
"OrthoDB": [
"3471593at2759"
],
"PhylomeDB": [
"O43193"
],
"TreeFam": [
"TF336314"
],
"PathwayCommons": [
"O43193"
],
"Reactome": [
"R-HSA-375276",
"R-HSA-416476"
],
"SignaLink": [
"O43193"
],
"SIGNOR": [
"O43193"
],
"BioGRID-ORCS": [
"2862"
],
"GeneWiki": [
"Motilin_receptor"
],
"GenomeRNAi": [
"2862"
],
"Pharos": [
"O43193"
],
"PRO": [
"PR:O43193"
],
"Proteomes": [
"UP000005640"
],
"RNAct": [
"O43193"
],
"Bgee": [
"ENSG00000102539"
],
"GO": [
"GO:0005829",
"GO:0005886",
"GO:0008528",
"GO:0042562",
"GO:0007186"
],
"Gene3D": [
"1.20.1070.10"
],
"InterPro": [
"IPR003905",
"IPR000276",
"IPR017452"
],
"PANTHER": [
"PTHR24243",
"PTHR24243:SF3"
],
"Pfam": [
"PF00001"
],
"PRINTS": [
"PR01417",
"PR00237"
],
"SMART": [
"SM01381"
],
"SUPFAM": [
"SSF81321"
],
"PROSITE": [
"PS00237",
"PS50262"
]
},
"citations": [
{
"title": "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors.",
"pubmedID": "9441746",
"doi": "10.1006\/geno.1997.5069"
},
{
"title": "Receptor for motilin identified in the human gastrointestinal system.",
"pubmedID": "10381885",
"doi": "10.1126\/science.284.5423.2184"
},
{
"title": "The DNA sequence and analysis of human chromosome 13.",
"pubmedID": "15057823",
"doi": "10.1038\/nature02379"
},
{
"title": "Growth hormone secretagogue receptor family members and ligands.",
"pubmedID": "11322507",
"doi": "10.1385\/endo:14:1:009"
}
],
"sequence": {
"length": 412,
"mass": 45344,
"checksum": "C13FF6165012DEF3",
"modified": {
"$date": {
"$numberLong": "896659200000"
}
},
"version": 1,
"sequence": "MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG"
},
"existence": 0,
"relevance": 1,
"proteinID": 1426992874
}
]
}