Details for: FCGR2C

Gene ID: 9103

Symbol: FCGR2C

Description: Fc gamma receptor IIc (gene/pseudogene)

Associated with

Other Information

Genular Protein ID: 2504388969

Symbol: FCG2C_HUMAN

Name: Low affinity immunoglobulin gamma Fc region receptor II-c

UniProtKB Accession Codes:

P31995 O00523 O00524 O00525

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID 1 BioGRID-ORCS 2 BioMuta 1 CDD 2 CTD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 6 GO 8 Gene3D 1 GeneCards 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MIM 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 Orphanet 1 PANTHER 2 PDB 3 PDBsum 2 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 2 SMR 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2531080

Title: Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

PubMed ID: 2531080

DOI: 10.1002/j.1460-2075.1989.tb08540.x

PubMed ID: 9516136

Title: Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.

PubMed ID: 9516136

PubMed ID: 8756631

Title: In vivo and in vitro specificity of protein tyrosine kinases for immunoglobulin G receptor (FcgammaRII) phosphorylation.

PubMed ID: 8756631

DOI: 10.1128/mcb.16.9.4735

PubMed ID: 23744091

Title: Engineered antibody Fc variant with selectively enhanced FcgammaRIIb binding over both FcgammaRIIa(R131) and FcgammaRIIa(H131).

PubMed ID: 23744091

DOI: 10.1093/protein/gzt022

Sequence Information:

  • Length: 323
  • Mass: 35578
  • Checksum: DC4C1A22A0DE4572
  • Sequence:
    • MGILSFLPVL ATESDWADCK SPQPWGHMLL WTAVLFLAPV AGTPAAPPKA VLKLEPQWIN 
VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL 
SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN 
FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAPSSS PMGIIVAVVT GIAVAAIVAA 
VVALIYCRKK RISANSTDPV KAAQFEPPGR QMIAIRKRQP EETNNDYETA DGGYMTLNPR 
APTDDDKNIY LTLPPNDHVN SNN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.